SARS coronavirus nucleocapsid immunodominant T-cell epitope cluster is common to both exogenous recombinant and endogenous DNA-encoded immunogens

Virology

Volumn 347, Issue 1, 2006, Pages 127-139

  Gupta, Vandana ^a   Tabiin, Tani M ^a   Sun, Kai ^a   Chandrasekaran, Ananth ^a   Anwar, Azlinda ^a   Yang, Kun ^b   Chikhlikar, Priya ^b   Salmon, Jerome ^b   Brusic, Vladimir ^c,d   Marques, Ernesto T A ^b,e   Kellathur, Srinivasan N ^a,b   August, Thomas J ^a,b  

^a Johns Hopkins Singapore   (Singapore)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUTE FOR INFOCOMM RESEARCH   (Singapore)

^d UNIVERSITY OF QUEENSLAND   (Australia)

^e Aggeu Magalhaes Research Center   (Brazil)

Author keywords

Antigen peptide epitopes; ELISpot; LAMP N DNA construct; N DNA construct; Nucleocapsid protein; Recombinant N; Rodent; SARS coronavirus; T cells

Indexed keywords

CYTOPLASM PROTEIN; DNA; EPITOPE; FREUND ADJUVANT; GAMMA INTERFERON; NUCLEOCAPSID GLUTATHIONE S TRANFERASE; NUCLEOCAPSID LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; NUCLEOCAPSID PROTEIN; PEPTIDE DERIVATIVE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CHIMERA; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENZYME LINKED IMMUNOSPOT ASSAY; GENETIC TRANSFECTION; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOELECTRON MICROSCOPY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; SARS CORONAVIRUS; SCORING SYSTEM; T LYMPHOCYTE; VIRUS NUCLEOCAPSID;

AMINO ACID SEQUENCE; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, VIRAL; BASE SEQUENCE; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; DNA, VIRAL; IMMUNODOMINANT EPITOPES; MICE; MICROSCOPY, IMMUNOELECTRON; MOLECULAR SEQUENCE DATA; NUCLEOCAPSID PROTEINS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SARS VIRUS; SPODOPTERA; T-LYMPHOCYTES; TRANSFECTION; VIRAL VACCINES;

ANIMALIA; RODENTIA; SARS CORONAVIRUS;

EID: 33645033681     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2005.11.042     Document Type: Article

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