3-D structure of multilaminar lysosomes in antigen presenting cells reveals trapping of MHC II on the internal membranes

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Volumn 5, Issue 12, 2004, Pages 936-945

  Murk, Jean Luc A N ^a   Lebbink, Misjaèl N ^b   Humbel, Bruno M ^b   Geerts, Willie J C ^b   Griffith, Janice M ^a   Langenberg, Dennis M L ^c   Verreck, Frank A W ^c   Verkleij, Arie J ^b   Koster, Abraham J ^b   Geuze, Hans J ^a   Kleijmeer, Monique J ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Antigen presentation; Electron tomography; MHC II; Multilaminar lysosome; Organelle biogenesis

Indexed keywords

ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDE;

ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CELL ACTIVATION; CELL MEMBRANE; CELL SURFACE; CELL VACUOLE; CONTROLLED STUDY; DENDRITIC CELL; ENDOSOME; HELPER CELL; HUMAN; HUMAN CELL; IMAGE RECONSTRUCTION; IMMOBILIZED CELL; IMMUNE RESPONSE; INTERNALIZATION; LYSOSOME; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN TRANSPORT; STRUCTURE ANALYSIS; T LYMPHOCYTE ACTIVATION; THREE DIMENSIONAL IMAGING; TOMOGRAPHY;

ANTIGEN-PRESENTING CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; INTRACELLULAR MEMBRANES; LYSOSOMES; MICROSCOPY, ELECTRON; RIBOSOMAL PROTEINS;

EID: 8844276804     PISSN: 13989219     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2004.00235.x     Document Type: Article

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