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4644237821
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For a description of biological assays and additional data on compounds 1 and 2, see: T.-A. Lin, K.W. McIntyre, J. Das, C. Liu, K.D. O'Day, B. Penhallow, C.-Y. Hung, G.S. Whitney, D.J. Shuster, X. Yang, R. Townsend, J. Postelnek, S.H. Spergel, J. Lin, R.V. Moquin, J.A. Furch, A.V. Kamath, H. Zhang, P.H. Marathe, J.J. Perez-Villar, A. Doweyko, L. Killar, J.H. Dodd, J.C. Barrish, J. Wityak, and S.B. Kanner Biochemistry 43 2004 11056
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Shan, W.10
Mitt, T.11
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Poss, M.A.13
Zhu, H.14
Sack, J.S.15
Tokarski, J.S.16
Chang, C.Y.17
Pavelitch, N.18
Kamath, A.19
Humphreys, W.G.20
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Burusker, I.22
Kellar, K.A.23
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more..
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33644968747
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note
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Methyl 5-chloromethyl-2,3-dimethylbenzoate was prepared from methyl 2,3-dimethylbenzoate by treatment with methoxymethyl chloride and thionyl chloride in the presence of ferric chloride at 55°C for 2 h (42% yield).
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