Overexpression of leucyl aminopeptidase in Plasmodium falciparum parasites: Target for the antimalarial activity of bestatin

Journal of Biological Chemistry

Volumn 281, Issue 3, 2006, Pages 1741-1745

  Gardiner, Donald L ^a   Trenholme, Katharine R ^a   Skinner Adams, Tina S ^a   Stack, Colin M ^b   Dalton, John P ^a,b  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; DRUG PRODUCTS; OSMOSIS; POLYPEPTIDES;

BESTATIN; MALARIA CELLS; OSMOTIC STABILITY;

ENZYMES;

BESTATIN; CYTOSOL AMINOPEPTIDASE; ANTIMALARIAL AGENT; DRUG DERIVATIVE; LEUCINE; PRIMER DNA; PROTEINASE INHIBITOR; PROTOZOAL PROTEIN; RECOMBINANT PROTEIN;

ANTIMALARIAL ACTIVITY; ARTICLE; CYTOSOL; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IN VITRO STUDY; MALARIA; NONHUMAN; NORTHERN BLOTTING; PARASITE DEVELOPMENT; PLASMID; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; TRANSGENE; TRANSGENIC ORGANISM; WILD TYPE; ANIMAL; ENZYMOLOGY; EXON; GENETICS; KINETICS; METABOLISM; NUCLEOTIDE SEQUENCE; TRANSGENIC ANIMAL;

PLASMODIUM FALCIPARUM;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIMALARIALS; BASE SEQUENCE; DNA PRIMERS; EXONS; KINETICS; LEUCINE; LEUCYL AMINOPEPTIDASE; PLASMODIUM FALCIPARUM; PROTEASE INHIBITORS; PROTOZOAN PROTEINS; RECOMBINANT PROTEINS; TRANSFECTION;

EID: 33644978572     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M508955200     Document Type: Article

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