A Plasmodium falciparum aminopeptidase gene belonging to the M1 family of zinc-metallopeptidases is expressed in erythrocytic stages

Molecular and Biochemical Parasitology

Volumn 97, Issue 1-2, 1998, Pages 149-160

  Florent, Isabelle ^a   Derhy, Zakia ^a   Allary, Marina ^a   Monsigny, Michel ^b   Mayer, Roger ^b   Schrével, Joseph ^a  

^a MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^b CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

Author keywords

Gene; Malaria; Plasmodium falciparum; Zinc metallopeptidase

Indexed keywords

AMINOPEPTIDASE; ANTISERUM; METALLOPROTEINASE; ZINC ION;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ERYTHROCYTE; GENE LIBRARY; IMMUNOBLOTTING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMODIUM FALCIPARUM; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SCHIZONT;

AMINO ACID SEQUENCE; AMINOPEPTIDASES; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; ERYTHROCYTES; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE LIBRARY; GENES, PROTOZOAN; LIFE CYCLE STAGES; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT;

ESCHERICHIA COLI; EUKARYOTA; PLASMODIUM FALCIPARUM; PROKARYOTA;

EID: 0032583101     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(98)00143-1     Document Type: Article

References (40)

1. Wellems T.E. Molecular genetics of drug resistance in Plasmodium falciparum malaria. Parasitol. Today. 10:1991;110-121.
2. Schrével J., Deguercy A., Mayer R., Monsigny M. Proteases in malaria-infected red cells. Blood Cells. 16:1990;563-584.
3. Braun-Breton C., Pereira da Silva L. Plasmodium and the infected erythrocyte-malaria proteases and the red blood cell invasion. Parasitol. Today. 9:1993;92-96.
4. Francis S.E., Sullivan D.J., Goldberg D.E. Haemoglobin metabolism in the malaria parasite Plasmodium falciparum. Annu. Rev. Microbiol. 51:1997;97-123.
5. Rosenthal P.J. Proteases of malarial parasites: new targets for chemotherapy. Emerg. Infect. Dis. 4:1998;49-57.
6. Ring C.S., Sun E., McKerrow J.H. et al. Structure-based inhibitor design by using protein models for the development of antiparasitic agents. Proc. Natl. Acad. Sci. USA. 90:1993;3583-3587.
7. Silva A.M., Lee A.Y., Gulnik S.V. et al. Structure and inhibition of Plasmepsin II, a haemoglobin-degrading enzyme from Plasmodium falciparum. Proc. Natl. Acad. Sci. USA. 93:1996;10034-10039.
8. Grellier P., Picard I., Bernard F., Mayer R., Heidrich H.G., Monsigny M., Schrével J. Purification and identification of a neutral endopeptidase in Plasmodium falciparum schizonts and merozoites. Parasitol. Res. 75:1989;455-460.
9. Bonnefoy S., Gysin J., Blisnick T., Guillotte M., Carcy B., Pereira da Silva L., Mercereau-Puijalon O. Immunogenicity and antigenicity of a Plasmodium falciparum protein fraction (90-110 kDa) able to protect squirrel monkeys against asexual blood stages. Vaccine. 12:1994;32-40.
10. Trager W., Jensen J.B. Human malarial parasites in continuous culture. Science. 193:1976;673-675.
11. Sambrook J., Fritsch E.F., Maniatis T. Molecular Cloning, A Laboratory Manual. 2nd:1989;Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.
12. Ochman H., Medhora M.M., Garza D., Hartl D.L. Amplification of flanking sequences by inverse PCR. PCR Protocols, A Guide to Methods and Applications. 1990;Academic Press/Harcourt Brace Jovanovich, New York.
13. Sanger F., Nicklen S., Coulson A.R. DNA sequencing with chain terminating inhibitors. Proc. Natl. Acad. Sci. USA. 74:1977;5463-5467.
14. Dessen P., Fondrat C., Valencien C., Mugnier C. Bisance, a French service for access to biomolecular sequence databases. Cabios. 6:1990;355-356.
15. Pearson W.R., Lipman D.J. Improved tools for biological sequence comparison. Proc. Natl. Acad. Sci. USA. 85:1988;2444-2448.
16. Higgins D.G. Clustal V: multiple alignments of DNA and protein sequences. Methods Mol. Biol. 25:1994;307-318.
17. Tam J.P. Synthetic peptide vaccine design: synthesis and properties of a high-density multiple antigenic peptide system. Proc. Natl. Acad. Sci. USA. 85:1988;5409-5413.
18. Weber J.L. Analysis of sequences from the extremely A+T rich genome of Plasmodium falciparum. Gene. 52:1987;103-109.
19. Saul A., Battistutta D. Codon usage in Plasmodium falciparum. Mol. Biochem. Parasitol. 27:1988;35-42.
20. Rawlings N.D., Barrett A.J. Evolutionary families of metallopeptidases. Methods Enzymol. 248:1995;183-228.
21. Foglino M., Gharbi S., Lazdzunski A. Nucleotide sequence of the pepN gene encoding aminopeptidase N of Escherichia coli. Gene. 49:1986;303-309.
22. Fleishman R.D., Adams M.D., White O. et al. Complete genome of Haemophilius influenza. Science. 269:1995;496-512.
23. Kester W.R., Matthews B.W. Crystallographic study of the binding of dipeptide inhibitors to thermolysin: implications for the mechanism of catalysis. Biochemistry. 16:1977;2506-2516.
24. Vazeux G., Itturioz X., Corvol P., Llorenscortes C. A tyrosine residue essential for catalytic activity in aminopeptidase A. Biochem. J. 327:1997;883-889.
25. Laustsen P.G., Rasmussen T.E., Petersen K. et al. The complete amino acid sequence of human placental oxytocinase. Biochim. Biophys. Acta. 1352:1997;1-7.
26. Curley G.P., O'Donovan S.M., McNally J. et al. Aminopeptidases from Plasmodium falciparum, Plasmodium chabaudi chabaudi and Plasmodium berghei. J. Eukaryot. Microbiol. 41:1993;119-123.
27. Kyte J., Doolitle R.F. A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157:1982;105-132.
28. Jameson B.A., Wolf H. The antigenic index: a novel algorithm for predicting antigenic determinants. Comput. Appl. Biosci. 4:1988;181-186.
29. Vander Jagt D.L., Baack B.R., Hunsaker L.A. Purification and characterisation of an aminopeptidase from Plasmodium falciparum. Mol. Biochem. Parasitol. 10:1984;45-54.
30. Gyang F.N., Poole B., Trager W. Peptidases from Plasmodium falciparum cultured in vitro. Mol. Biochem. Parasitol. 5:1982;263-273.
31. Nankya-Kitaka M.F., Curley G.P., Gavigan C.S., Bell A., Dalton J.P. Plasmodium chabaudi chabaudi and P. falciparum: inhibition of aminopeptidase and parasite growth by bestatin and nitrobestatin. Parasitol. Res. 84:1998;552-558.
32. Charet P., Aissi E., Maurois P., Bouquelet S., Biguet J. Aminopeptidases in rodent Plasmodium. Comp. Biochem. Physiol. B65:1980;519-524.
33. Vander Jagt D.L. Parasite proteases and. antimalarial activities of the protease inhibitors. Malaria Red Cell. 2:1989;105-118.
34. Kolakovich K.A., Gluzman I.Y., Duffin K.L., Goldberg D.E. Generation of haemoglobin peptides in the acidic digestive vacuole of Plasmodium falciparum implicates peptides transport in amino acid production. Mol. Biochem. Parasitol. 87:1997;123-135.
35. Umezawa H., Aoyagi T. Trends in research in low molecular weight proteinase inhibitor of microbial origin. Katunuma N., Umezawa H., Holzer H. Proteinase Inhibitors. 1983;3-15 Jpn Sci Soc Press/Springer, Tokyo/Berlin.
36. Olaya P., Wasserman M. Effect of calpain inhibitors on the invasion of human erythrocytes by the parasite Plasmodium falciparum. Biochim. Biophys. Acta. 1096:1991;217-222.
37. Klein J.K., Klein U., Schad M., Plapp R. Cloning, DNA sequence analysis and partial characterisation of pepN, a lysyl aminopeptidase from Lactobacillus delbrückii ssp. lactis DSM7290. Eur. J. Biochem. 217:1993;105-114.
38. Garcia-Alvarez N., Cueva R., Suarez-Rendueles P. Molecular cloning of soluble aminopeptidases from Saccharomyces cerevisiae. Eur. J. Biochem. 202:1991;993-1002.
39. Olsen J., Cowell G.M., Koenigshoefer E. et al. Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA. FEBS Lett. 238:1988;307-314.
40. Minami M., Ohno S., Kawasaki H. et al. Molecular cloning of a cDNA coding for human leukotriene A4 hydrolase. Complete primary structure of an enzyme involved in eicosanoid synthesis. J. Biol. Chem. 262:1987;13873-13876.