메뉴 건너뛰기




Volumn 273, Issue 3, 2006, Pages 577-587

Major phosphorylation of SF1 on adjacent Ser-Pro motifs enhances interaction with U2AF65

Author keywords

Kinase KIS; Protein phosphorylation; RNA splicing; SF1; U2AF homology motif

Indexed keywords

PROLINE; PROTEIN; PROTEIN KINASE; PROTEIN SPLICING FACTOR 1; PROTEIN SUBUNIT; RNA; SERINE; UNCLASSIFIED DRUG;

EID: 33644944537     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.05091.x     Document Type: Article
Times cited : (48)

References (54)
  • 1
    • 0036948420 scopus 로고    scopus 로고
    • Allosteric cascade of spliceosome activation
    • Brow DA 2002 Allosteric cascade of spliceosome activation Annu Rev Genet 36 333 360
    • (2002) Annu Rev Genet , vol.36 , pp. 333-360
    • Brow, D.A.1
  • 2
    • 0026731973 scopus 로고
    • Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing
    • Mermoud JE Cohen P Lamond AI 1992 Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing Nucl Acids Res 20 5263 5269
    • (1992) Nucl Acids Res , vol.20 , pp. 5263-5269
    • Mermoud, J.E.1    Cohen, P.2    Lamond, A.I.3
  • 3
    • 0028043718 scopus 로고
    • Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism
    • Mermoud JE Cohen PT Lamond AI 1994 Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism EMBO J 13 5679 5688
    • (1994) EMBO J , vol.13 , pp. 5679-5688
    • Mermoud, J.E.1    Cohen, P.T.2    Lamond, A.I.3
  • 5
    • 14644445227 scopus 로고    scopus 로고
    • SRprises along a messenger's journey
    • Huang Y Steitz JA 2005 SRprises along a messenger's journey Mol Cell 17 613 615
    • (2005) Mol Cell , vol.17 , pp. 613-615
    • Huang, Y.1    Steitz, J.A.2
  • 6
    • 0027962510 scopus 로고
    • Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors
    • Gui JF Tronchere H Chandler SD Fu XD 1994 Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors Proc Natl Acad Sci USA 91 10824 10828
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10824-10828
    • Gui, J.F.1    Tronchere, H.2    Chandler, S.D.3    Fu, X.D.4
  • 7
    • 0032559642 scopus 로고    scopus 로고
    • SRPK2: A differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells
    • Wang HY Lin W Dyck JA Yeakley JM Songyang Z Cantley LC Fu XD 1998 SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells J Cell Biol 140 737 750
    • (1998) J Cell Biol , vol.140 , pp. 737-750
    • Wang, H.Y.1    Lin, W.2    Dyck, J.A.3    Yeakley, J.M.4    Songyang, Z.5    Cantley, L.C.6    Fu, X.D.7
  • 8
    • 0030028882 scopus 로고    scopus 로고
    • The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution
    • Colwill K Pawson T Andrews B Prasad J Manley JL Bell JC Duncan PI 1996 The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution EMBO J 15 265 275
    • (1996) EMBO J , vol.15 , pp. 265-275
    • Colwill, K.1    Pawson, T.2    Andrews, B.3    Prasad, J.4    Manley, J.L.5    Bell, J.C.6    Duncan, P.I.7
  • 9
    • 0031877713 scopus 로고    scopus 로고
    • Cyclin e associates with components of the pre-mRNA splicing machinery in mammalian cells
    • Seghezzi W Chua K Shanahan F Gozani O Reed R Lees E 1998 Cyclin E associates with components of the pre-mRNA splicing machinery in mammalian cells Mol Cell Biol 18 4526 4536
    • (1998) Mol Cell Biol , vol.18 , pp. 4526-4536
    • Seghezzi, W.1    Chua, K.2    Shanahan, F.3    Gozani, O.4    Reed, R.5    Lees, E.6
  • 10
    • 0032523934 scopus 로고    scopus 로고
    • Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis
    • Wang C Chua K Seghezzi W Lees E Gozani O Reed R 1998 Phosphorylation of spliceosomal protein SAP 155 coupled with splicing catalysis Genes Dev 12 1409 1414
    • (1998) Genes Dev , vol.12 , pp. 1409-1414
    • Wang, C.1    Chua, K.2    Seghezzi, W.3    Lees, E.4    Gozani, O.5    Reed, R.6
  • 11
    • 4444272979 scopus 로고    scopus 로고
    • Cell signalling and the control of pre-mRNA splicing
    • Shin C Manley JL 2004 Cell signalling and the control of pre-mRNA splicing Nat Rev Mol Cell Biol 5 727 738
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 727-738
    • Shin, C.1    Manley, J.L.2
  • 13
    • 0026668641 scopus 로고
    • Purification of splicing factor SF1, a heat-stable protein that functions in the assembly of a presplicing complex
    • Kramer A 1992 Purification of splicing factor SF1, a heat-stable protein that functions in the assembly of a presplicing complex Mol Cell Biol 12 4545 4552
    • (1992) Mol Cell Biol , vol.12 , pp. 4545-4552
    • Kramer, A.1
  • 14
    • 0030911051 scopus 로고    scopus 로고
    • Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals
    • Abovich N Rosbash M 1997 Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals Cell 89 403 412
    • (1997) Cell , vol.89 , pp. 403-412
    • Abovich, N.1    Rosbash, M.2
  • 15
    • 0032521186 scopus 로고    scopus 로고
    • A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition
    • Berglund JA Abovich N Rosbash M 1998 A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition Genes Dev 12 858 867
    • (1998) Genes Dev , vol.12 , pp. 858-867
    • Berglund, J.A.1    Abovich, N.2    Rosbash, M.3
  • 16
    • 0031958545 scopus 로고    scopus 로고
    • Conservation of functional domains involved in RNA binding and protein-protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1
    • Rain JC Rafi Z Rhani Z Legrain P Kramer A 1998 Conservation of functional domains involved in RNA binding and protein-protein interactions in human and Saccharomyces cerevisiae pre-mRNA splicing factor SF1 RNA 4 551 565
    • (1998) RNA , vol.4 , pp. 551-565
    • Rain, J.C.1    Rafi, Z.2    Rhani, Z.3    Legrain, P.4    Kramer, A.5
  • 17
    • 0030696675 scopus 로고    scopus 로고
    • The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC
    • Berglund JA Chua K Abovich N Reed R Rosbash M 1997 The splicing factor BBP interacts specifically with the pre-mRNA branchpoint sequence UACUAAC Cell 89 781 787
    • (1997) Cell , vol.89 , pp. 781-787
    • Berglund, J.A.1    Chua, K.2    Abovich, N.3    Reed, R.4    Rosbash, M.5
  • 18
    • 0031878108 scopus 로고    scopus 로고
    • A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site
    • Gozani O Potashkin J Reed R 1998 A potential role for U2AF-SAP 155 interactions in recruiting U2 snRNP to the branch site Mol Cell Biol 18 4752 4760
    • (1998) Mol Cell Biol , vol.18 , pp. 4752-4760
    • Gozani, O.1    Potashkin, J.2    Reed, R.3
  • 19
    • 0024743838 scopus 로고
    • Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing
    • Wu J Manley JL 1989 Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing Genes Dev 3 1553 1561
    • (1989) Genes Dev , vol.3 , pp. 1553-1561
    • Wu, J.1    Manley, J.L.2
  • 20
    • 0024744567 scopus 로고
    • A compensatory base change in human U2 snRNA can suppress a branch site mutation
    • Zhuang Y Weiner AM 1989 A compensatory base change in human U2 snRNA can suppress a branch site mutation Genes Dev 3 1545 1552
    • (1989) Genes Dev , vol.3 , pp. 1545-1552
    • Zhuang, Y.1    Weiner, A.M.2
  • 21
    • 0033575670 scopus 로고    scopus 로고
    • Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly
    • Wang X Bruderer S Rafi Z Xue J Milburn PJ Kramer A Robinson PJ 1999 Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly EMBO J 18 4549 4559
    • (1999) EMBO J , vol.18 , pp. 4549-4559
    • Wang, X.1    Bruderer, S.2    Rafi, Z.3    Xue, J.4    Milburn, P.J.5    Kramer, A.6    Robinson, P.J.7
  • 22
    • 0035823011 scopus 로고    scopus 로고
    • A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer
    • Kielkopf CL Rodionova NA Green MR Burley SK 2001 A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer Cell 106 595 605
    • (2001) Cell , vol.106 , pp. 595-605
    • Kielkopf, C.L.1    Rodionova, N.A.2    Green, M.R.3    Burley, S.K.4
  • 23
  • 24
    • 3042737403 scopus 로고    scopus 로고
    • U2AF homology motifs: Protein recognition in the RRM world
    • Kielkopf CL Lucke S Green MR 2004 U2AF homology motifs: protein recognition in the RRM world Genes Dev 18 1513 1526
    • (2004) Genes Dev , vol.18 , pp. 1513-1526
    • Kielkopf, C.L.1    Lucke, S.2    Green, M.R.3
  • 25
    • 0028943627 scopus 로고
    • Stathmin interaction with a putative kinase and coiled-coil-forming protein domains
    • Maucuer A Camonis JH Sobel A 1995 Stathmin interaction with a putative kinase and coiled-coil-forming protein domains Proc Natl Acad Sci USA 92 3100 3104
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3100-3104
    • Maucuer, A.1    Camonis, J.H.2    Sobel, A.3
  • 27
    • 0033942006 scopus 로고    scopus 로고
    • Specific Ser-Pro phosphorylation by the RNA-recognition motif containing kinase KIS
    • Maucuer A Le Caer JP Manceau V Sobel A 2000 Specific Ser-Pro phosphorylation by the RNA-recognition motif containing kinase KIS Eur J Biochem 267 4456 4464
    • (2000) Eur J Biochem , vol.267 , pp. 4456-4464
    • Maucuer, A.1    Le Caer, J.P.2    Manceau, V.3    Sobel, A.4
  • 28
    • 0036645678 scopus 로고    scopus 로고
    • A growth factor-dependent nuclear kinase phosphorylates p27 (Kip1) and regulates cell cycle progression
    • Boehm M Yoshimoto T Crook MF Nallamshetty S True A Nabel GJ Nabel EG 2002 A growth factor-dependent nuclear kinase phosphorylates p27 (Kip1) and regulates cell cycle progression EMBO J 21 3390 3401
    • (2002) EMBO J , vol.21 , pp. 3390-3401
    • Boehm, M.1    Yoshimoto, T.2    Crook, M.F.3    Nallamshetty, S.4    True, A.5    Nabel, G.J.6    Nabel, E.G.7
  • 30
    • 0030595187 scopus 로고    scopus 로고
    • Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA [corrected]
    • Valcarcel J Gaur RK Singh R Green MR 1996 Interaction of U2AF65 RS region with pre-mRNA branch point and promotion of base pairing with U2 snRNA [corrected] Science 273 1706 1709
    • (1996) Science , vol.273 , pp. 1706-1709
    • Valcarcel, J.1    Gaur, R.K.2    Singh, R.3    Green, M.R.4
  • 31
    • 8644268780 scopus 로고    scopus 로고
    • A pathway of sequential arginine-serine-rich domain-splicing signal interactions during mammalian spliceosome assembly
    • Shen H Green MR 2004 A pathway of sequential arginine-serine-rich domain-splicing signal interactions during mammalian spliceosome assembly Mol Cell 16 363 373
    • (2004) Mol Cell , vol.16 , pp. 363-373
    • Shen, H.1    Green, M.R.2
  • 32
    • 0029949698 scopus 로고    scopus 로고
    • Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA
    • Arning S Gruter P Bilbe G Kramer A 1996 Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA RNA 2 794 810
    • (1996) RNA , vol.2 , pp. 794-810
    • Arning, S.1    Gruter, P.2    Bilbe, G.3    Kramer, A.4
  • 34
    • 2642521977 scopus 로고    scopus 로고
    • Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line
    • Shu H Chen S Bi Q Mumby M Brekken DL 2004 Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line Mol Cell Proteomics 3 279 286
    • (2004) Mol Cell Proteomics , vol.3 , pp. 279-286
    • Shu, H.1    Chen, S.2    Bi, Q.3    Mumby, M.4    Brekken, D.L.5
  • 35
    • 0036535975 scopus 로고    scopus 로고
    • Pinning down proline-directed phosphorylation signaling
    • Lu KP Liou YC Zhou XZ 2002 Pinning down proline-directed phosphorylation signaling Trends Cell Biol 12 164 172
    • (2002) Trends Cell Biol , vol.12 , pp. 164-172
    • Lu, K.P.1    Liou, Y.C.2    Zhou, X.Z.3
  • 36
    • 0026661948 scopus 로고
    • Protein components specifically associated with prespliceosome and spliceosome complexes
    • Bennett M Michaud S Kingston J Reed R 1992 Protein components specifically associated with prespliceosome and spliceosome complexes Genes Dev 6 1986 2000
    • (1992) Genes Dev , vol.6 , pp. 1986-2000
    • Bennett, M.1    Michaud, S.2    Kingston, J.3    Reed, R.4
  • 37
    • 0034948027 scopus 로고    scopus 로고
    • Recognition of RNA branch point sequences by the KH domain of splicing factor 1 (mammalian branch point binding protein) in a splicing factor complex
    • Peled-Zehavi H Berglund JA Rosbash M Frankel AD 2001 Recognition of RNA branch point sequences by the KH domain of splicing factor 1 (mammalian branch point binding protein) in a splicing factor complex Mol Cell Biol 21 5232 5241
    • (2001) Mol Cell Biol , vol.21 , pp. 5232-5241
    • Peled-Zehavi, H.1    Berglund, J.A.2    Rosbash, M.3    Frankel, A.D.4
  • 38
    • 0024408832 scopus 로고
    • Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor
    • Zamore PD Green MR 1989 Identification, purification, and biochemical characterization of U2 small nuclear ribonucleoprotein auxiliary factor Proc Natl Acad Sci USA 86 9243 9247
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9243-9247
    • Zamore, P.D.1    Green, M.R.2
  • 39
    • 0026569967 scopus 로고
    • Cloning and domain structure of the mammalian splicing factor U2AF
    • Zamore PD Patton JG Green MR 1992 Cloning and domain structure of the mammalian splicing factor U2AF Nature 355 609 614
    • (1992) Nature , vol.355 , pp. 609-614
    • Zamore, P.D.1    Patton, J.G.2    Green, M.R.3
  • 40
    • 0037107372 scopus 로고    scopus 로고
    • Pre-spliceosome formation in S. pombe requires a stable complex of SF1-U2AF(59)-U2AF(23)
    • Huang T Vilardell J Query CC 2002 Pre-spliceosome formation in S. pombe requires a stable complex of SF1-U2AF(59)-U2AF(23) EMBO J 21 5516 5526
    • (2002) EMBO J , vol.21 , pp. 5516-5526
    • Huang, T.1    Vilardell, J.2    Query, C.C.3
  • 41
    • 0028273768 scopus 로고
    • The yeast MUD2 protein: An interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition
    • Abovich N Liao XC Rosbash M 1994 The yeast MUD2 protein: an interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition Genes Dev 8 843 854
    • (1994) Genes Dev , vol.8 , pp. 843-854
    • Abovich, N.1    Liao, X.C.2    Rosbash, M.3
  • 42
    • 0345593813 scopus 로고    scopus 로고
    • Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly
    • Rutz B Seraphin B 1999 Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly RNA 5 819 831
    • (1999) RNA , vol.5 , pp. 819-831
    • Rutz, B.1    Seraphin, B.2
  • 43
    • 0030934772 scopus 로고    scopus 로고
    • In vivo commitment to splicing in yeast involves the nucleotide upstream from the branch site conserved sequence and the Mud2 protein
    • Rain JC Legrain P 1997 In vivo commitment to splicing in yeast involves the nucleotide upstream from the branch site conserved sequence and the Mud2 protein EMBO J 16 1759 1771
    • (1997) EMBO J , vol.16 , pp. 1759-1771
    • Rain, J.C.1    Legrain, P.2
  • 44
    • 14844312915 scopus 로고    scopus 로고
    • Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo
    • Tanackovic G Kramer A 2005 Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo Mol Biol Cell 16 1366 1377
    • (2005) Mol Biol Cell , vol.16 , pp. 1366-1377
    • Tanackovic, G.1    Kramer, A.2
  • 45
    • 0034529379 scopus 로고    scopus 로고
    • Kinetic role for mammalian SF1/BBP in spliceosome assembly and function after polypyrimidine tract recognition by U2AF
    • Guth S Valcarcel J 2000 Kinetic role for mammalian SF1/BBP in spliceosome assembly and function after polypyrimidine tract recognition by U2AF J Biol Chem 275 38059 38066
    • (2000) J Biol Chem , vol.275 , pp. 38059-38066
    • Guth, S.1    Valcarcel, J.2
  • 46
    • 1642540276 scopus 로고    scopus 로고
    • The conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF 65) is essential in vivo but dispensable for activity in vitro
    • Banerjee H Rahn A Gawande B Guth S Valcarcel J Singh R 2004 The conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF 65) is essential in vivo but dispensable for activity in vitro RNA 10 240 253
    • (2004) RNA , vol.10 , pp. 240-253
    • Banerjee, H.1    Rahn, A.2    Gawande, B.3    Guth, S.4    Valcarcel, J.5    Singh, R.6
  • 47
    • 0343729923 scopus 로고    scopus 로고
    • A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing
    • Rutz B Seraphin B 2000 A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing EMBO J 19 1873 1886
    • (2000) EMBO J , vol.19 , pp. 1873-1886
    • Rutz, B.1    Seraphin, B.2
  • 48
    • 0032549661 scopus 로고    scopus 로고
    • Human ZFM1 protein is a transcriptional repressor that interacts with the transcription activation domain of stage-specific activator protein
    • Zhang D Childs G 1998 Human ZFM1 protein is a transcriptional repressor that interacts with the transcription activation domain of stage-specific activator protein J Biol Chem 273 6868 6877
    • (1998) J Biol Chem , vol.273 , pp. 6868-6877
    • Zhang, D.1    Childs, G.2
  • 49
    • 0032541042 scopus 로고    scopus 로고
    • The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription
    • Zhang D Paley AJ Childs G 1998 The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription J Biol Chem 273 18086 18091
    • (1998) J Biol Chem , vol.273 , pp. 18086-18091
    • Zhang, D.1    Paley, A.J.2    Childs, G.3
  • 50
    • 0034774728 scopus 로고    scopus 로고
    • The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1
    • Goldstrohm AC Albrecht TR Sune C Bedford MT Garcia-Blanco MA 2001 The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1 Mol Cell Biol 21 7617 7628
    • (2001) Mol Cell Biol , vol.21 , pp. 7617-7628
    • Goldstrohm, A.C.1    Albrecht, T.R.2    Sune, C.3    Bedford, M.T.4    Garcia-Blanco, M.A.5
  • 52
    • 2942648436 scopus 로고    scopus 로고
    • Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs
    • Blanchette M Labourier E Green RE Brenner SE Rio DC 2004 Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs Mol Cell 14 775 786
    • (2004) Mol Cell , vol.14 , pp. 775-786
    • Blanchette, M.1    Labourier, E.2    Green, R.E.3    Brenner, S.E.4    Rio, D.C.5
  • 53
    • 0032574663 scopus 로고    scopus 로고
    • Diverse modes of alternative splicing of human splicing factor SF1 deduced from the exon-intron structure of the gene
    • Kramer A Quentin M Mulhauser F 1998 Diverse modes of alternative splicing of human splicing factor SF1 deduced from the exon-intron structure of the gene Gene 211 29 37
    • (1998) Gene , vol.211 , pp. 29-37
    • Kramer, A.1    Quentin, M.2    Mulhauser, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.