Insights into the hydrogen-abstraction reactions of diol dehydratase: Relevance to the catalytic mechanism and suicide inactivation

Journal of the American Chemical Society

Volumn 128, Issue 10, 2006, Pages 3433-3444

  Sandala, Gregory M ^a,b   Smith, David M ^c   Coote, Michelle L ^b,e   Golding, Bernard T ^d   Radom, Leo ^a,b,e  

^a UNIVERSITY OF SYDNEY   (Australia)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^c RUDER BO KOVI INSTITUTE   (Croatia)

^d NEWCASTLE UNIVERSITY   (United Kingdom)

^e Australian Government Australian Research Council   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC HYDROGEN-ABSTRACTION REACTIONS; HYDROGEN RE-ABSTRACTION; SUBSTRATE ANALOGUES;

ALCOHOLS; CATALYSIS; HYDROGEN; PARAFFINS; SUBSTRATES;

ENZYMES;

CHLOROACETALDEHYDE; COBAMAMIDE; DIOL DEHYDRATASE; GLYOXAL; HYDROGEN; HYDROLYASE; ISOTOPE; PROPYLENE GLYCOL; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL REACTION; DENSITY FUNCTIONAL THEORY; ENTHALPY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SUBSTRATE; QUANTUM MECHANICS;

ACETALDEHYDE; CATALYSIS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME ACTIVATION; ETHYLENE GLYCOL; FREE RADICALS; GLYOXAL; HYDROGEN; KINETICS; PROPANEDIOL DEHYDRATASE; PROPYLENE GLYCOL; QUANTUM THEORY; THERMODYNAMICS;

EID: 33644937821     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja057902q     Document Type: Article

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