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Volumn 59, Issue 3-4, 2006, Pages 124-129

Rationale for the use of melatonin as a protective agent against cosmic radiation and ischemia-reperfusion damage in long term spaceflight

Author keywords

Cosmic radiation; Hibernation; Ischemia reperfusion; Melatonin; Organ transplantation

Indexed keywords

FREE RADICAL SCAVENGERS; HIBERNATION; ISCHEMIA REPERFUSION; MAMMALIAN HIBERNATION; MELATONIN; PROTECTIVE AGENTS; RADIATION-INDUCED; SPACE MEDICINES;

EID: 33644892460     PISSN: 0007084X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (4)

References (87)
  • 1
    • 20044396413 scopus 로고    scopus 로고
    • Mutations induced by heavy charged particles
    • F. Yatagai, "Mutations induced by heavy charged particles", Biol. Sci. Space, 18, pp.224-434, 2004.
    • (2004) Biol. Sci. Space , vol.18 , pp. 224-434
    • Yatagai, F.1
  • 2
  • 3
    • 20044385122 scopus 로고    scopus 로고
    • The biological effects of space radiation during long stays in space
    • K. Ohnishi, and T. Ohnishi "The biological effects of space radiation during long stays in space", Biol. Sci. Space, 18, pp.201-205, 2004.
    • (2004) Biol. Sci. Space , vol.18 , pp. 201-205
    • Ohnishi, K.1    Ohnishi, T.2
  • 4
    • 11244320385 scopus 로고    scopus 로고
    • Cosmic radiation exposure and cancer risk among flight crew
    • A.J. Sigurdson and E. Ron, "Cosmic radiation exposure and cancer risk among flight crew", Cancer Invest., 22, pp.743-761, 2004.
    • (2004) Cancer Invest. , vol.22 , pp. 743-761
    • Sigurdson, A.J.1    Ron, E.2
  • 5
    • 4644340882 scopus 로고    scopus 로고
    • Environmental health physics-50 years of progress
    • D.W. Moeller, "Environmental health physics-50 years of progress", Health Phys., 87, pp.337-357, 2004.
    • (2004) Health Phys. , vol.87 , pp. 337-357
    • Moeller, D.W.1
  • 6
    • 0142025061 scopus 로고    scopus 로고
    • Fundamental space radiobiology
    • g.A. Nelson, "Fundamental space radiobiology", Gravit. Space Biol. Bull., 16, pp.29-36, 2003.
    • (2003) Gravit. Space Biol. Bull. , vol.16 , pp. 29-36
    • Nelson, G.A.1
  • 9
    • 4444347121 scopus 로고    scopus 로고
    • Radiation protection aspects of the cosmic radiation exposure of aircraft crew
    • D.T. Bartlett "Radiation protection aspects of the cosmic radiation exposure of aircraft crew", Radial. Prot. Dosimetry, 109, pp.349-355, 2004.
    • (2004) Radial. Prot. Dosimetry , vol.109 , pp. 349-355
    • Bartlett, D.T.1
  • 10
    • 0024195429 scopus 로고
    • DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation, and reparability
    • J.F. Ward "DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability", Prog. Nucleic Acid Res. Mol. Biol., 35, pp.95-125, 1988.
    • (1988) Prog. Nucleic Acid Res. Mol. Biol. , vol.35 , pp. 95-125
    • Ward, J.F.1
  • 11
    • 0025045198 scopus 로고
    • The role of 8-hydroxydeoxyguanosine in carcinogenesis
    • RA. Floyd "The role of 8-hydroxydeoxyguanosine in carcinogenesis", Carcinogenesis, 11, pp.1447-1450, 1990.
    • (1990) Carcinogenesis , vol.11 , pp. 1447-1450
    • Floyd, R.A.1
  • 12
    • 0031901226 scopus 로고    scopus 로고
    • X-radiation induced 8-hydroxy-2[prime]-deoxyguanosine formation in vivo in rat mammary gland DNA
    • A.D. Haegele, P. Wolfe and H.J. Thompson "X-radiation induced 8-hydroxy-2[prime]-deoxyguanosine formation in vivo in rat mammary gland DNA", Carcinogenesis, 19, pp.319-1321, 1998.
    • (1998) Carcinogenesis , vol.19 , pp. 319-1321
    • Haegele, A.D.1    Wolfe, P.2    Thompson, H.J.3
  • 13
    • 0028927261 scopus 로고
    • Reactions of oxyl radicals with DNA
    • A.P. Breen and J.A. Murphy, "Reactions of oxyl radicals with DNA", Free Radic. Biol. Med., 18, pp.1033-1077, 1995.
    • (1995) Free Radic. Biol. Med. , vol.18 , pp. 1033-1077
    • Breen, A.P.1    Murphy, J.A.2
  • 15
    • 0025972738 scopus 로고
    • DNA damage by oxygen-derived species
    • B. Halliwell and Aruoma O.I. "DNA damage by oxygen-derived species", FEBS Lett., 281, pp.9-19, 1990.
    • (1990) FEBS Lett. , vol.281 , pp. 9-19
    • Halliwell, B.1    Aruoma, O.I.2
  • 16
    • 0026347249 scopus 로고
    • Significance and measurement of DNA double strand breaks in mammalian cellA
    • M.C. Elia, J.G, DeLuca and M.O. Bradley, "Significance and measurement of DNA double strand breaks in mammalian cellA", Pharmacol. Ther., 51, pp.291-327, 1991.
    • (1991) Pharmacol. Ther. , vol.51 , pp. 291-327
    • Elia, M.C.1    DeLuca, J.G.2    Bradley, M.O.3
  • 17
    • 0032856296 scopus 로고    scopus 로고
    • Ionizing radiation and genetic risks. X. The potential "disease phenotypes" of radiation-induced genetic damage in humans: Perspectives from human molecular biology and radiation genetic
    • K. Sankaranarayanan, "Ionizing radiation and genetic risks. X. The potential "disease phenotypes" of radiation-induced genetic damage in humans: Perspectives from human molecular biology and radiation genetic", Mutat. Res., 429, pp.45-83, 1999.
    • (1999) Mutat. Res. , vol.429 , pp. 45-83
    • Sankaranarayanan, K.1
  • 18
  • 19
    • 0025803728 scopus 로고
    • Structural changes in plasma membranes prepared from irradiated Chinese hamster V79 cells as revealed by Raman spectroscop
    • S.P. Verma and N.A. Sonwalker, "Structural changes in plasma membranes prepared from irradiated Chinese hamster V79 cells as revealed by Raman spectroscop", Radiat. Res., 126, pp.27-35, 1991.
    • (1991) Radiat. Res. , vol.126 , pp. 27-35
    • Verma, S.P.1    Sonwalker, N.A.2
  • 20
    • 0028346769 scopus 로고
    • Evidence for an increase in water concentration in bilayers after oxidative damage of phospholipids induced by ionizing radiation
    • T. Parasassi, A.M. Giusti, E. Gratton, E. Monaco, M. Raimondi, G. Ravagnan and O.A. Sapora, "Evidence for an increase in water concentration in bilayers after oxidative damage of phospholipids induced by ionizing radiation", Int. J. Radiat. Biol., 65, pp.329-334, 1994.
    • (1994) Int. J. Radiat. Biol. , vol.65 , pp. 329-334
    • Parasassi, T.1    Giusti, A.M.2    Gratton, E.3    Monaco, E.4    Raimondi, M.5    Ravagnan, G.6    Sapora, O.A.7
  • 21
    • 0031792184 scopus 로고    scopus 로고
    • Human cell membrane oxidative damage induced by single and fractionated doses of ionizing radiation: A fluorescence spectroscopy study
    • A.M. Giusti, M. Raimondi, G. Rahavan, O. Sapora and T. Parasassi, "Human cell membrane oxidative damage induced by single and fractionated doses of ionizing radiation: A fluorescence spectroscopy study", Int. J. Radial. Biol., 74, pp.595-605, 1998.
    • (1998) Int. J. Radial. Biol. , vol.74 , pp. 595-605
    • Giusti, A.M.1    Raimondi, M.2    Rahavan, G.3    Sapora, O.4    Parasassi, T.5
  • 22
    • 0025866919 scopus 로고
    • Direct effects of ionizing radiation on integral membrane proteins
    • E. Jhun, B.H. Jhun and L.R. Jones, "Direct effects of ionizing radiation on integral membrane proteins", J. Biol. Chem., 266, pp.9403-9407, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 9403-9407
    • Jhun, E.1    Jhun, B.H.2    Jones, L.R.3
  • 23
    • 0027422270 scopus 로고
    • An immunochemical approach of identifying and characterizing protein targets of toxic reactive metabolites
    • L.R. Pohl, "An immunochemical approach of identifying and characterizing protein targets of toxic reactive metabolites", Chem. Res. Toxicol., 6, pp.786-793, 1993.
    • (1993) Chem. Res. Toxicol. , vol.6 , pp. 786-793
    • Pohl, L.R.1
  • 24
    • 0027528412 scopus 로고
    • Repair of DNA containing the oxidatively damaged base, 8-oxyguanine
    • J. Tchou and A.P. Grollman, "Repair of DNA containing the oxidatively damaged base, 8-oxyguanine". Mutat. Res., 299, pp.277-287, 1993.
    • (1993) Mutat. Res. , vol.299 , pp. 277-287
    • Tchou, J.1    Grollman, A.P.2
  • 25
    • 0031773901 scopus 로고    scopus 로고
    • Enzymatic processing of radiation-induced free radical damage in DNA
    • S.S. Wallace, "Enzymatic processing of radiation-induced free radical damage in DNA", Radiat. Res., 150, pp.S60-S79, 1998.
    • (1998) Radiat. Res. , vol.150
    • Wallace, S.S.1
  • 26
    • 0027209389 scopus 로고
    • Strategies of antioxidant defense
    • H. Sies, "Strategies of antioxidant defense", Eur. J. Biochem., 215, pp.213-219, 1993.
    • (1993) Eur. J. Biochem. , vol.215 , pp. 213-219
    • Sies, H.1
  • 27
    • 0032990005 scopus 로고    scopus 로고
    • The antioxidant status of patients subjected to total body irradiation
    • S. Chevion, R Or and E.M. Berry, "The antioxidant status of patients subjected to total body irradiation", Biochem. Mol. Biol. Int, 47, pp.1019-1027, 1999.
    • (1999) Biochem. Mol. Biol. Int , vol.47 , pp. 1019-1027
    • Chevion, S.1    Or, R.2    Berry, E.M.3
  • 28
    • 20744456913 scopus 로고    scopus 로고
    • Rationale for using multiple antioxidants in protecting humans against low doses of ionizing radiation
    • K.M. Prasad, "Rationale for using multiple antioxidants in protecting humans against low doses of ionizing radiation", Br. J. Radiol., 78, pp.485-492, 2005.
    • (2005) Br. J. Radiol. , vol.78 , pp. 485-492
    • Prasad, K.M.1
  • 30
    • 0141528621 scopus 로고    scopus 로고
    • Mammalian hibernation: Cellular and molecular responses to depressed metabolism and low temperature
    • H.V. Carey, M.T. Andrews and S.L. Martin, "Mammalian hibernation: cellular and molecular responses to depressed metabolism and low temperature", Physiol. Rev., 83, pp.1153-1181, 2003.
    • (2003) Physiol. Rev. , vol.83 , pp. 1153-1181
    • Carey, H.V.1    Andrews, M.T.2    Martin, S.L.3
  • 31
    • 20244390001 scopus 로고    scopus 로고
    • 2S induces a suspended animation-like status in mice
    • 2S induces a suspended animation-like status in mice", Science, 308, p.518, 2005.
    • (2005) Science , vol.308 , pp. 518
    • Blackstone, E.1    Morrison, M.2    Roth, M.B.3
  • 32
    • 0034741612 scopus 로고    scopus 로고
    • Changes in gut function during hibernation: Implications for bowel transplantation and surgery
    • H.V. Carey, M.J. Mangino and J.H. Southard, "Changes in gut function during hibernation: implications for bowel transplantation and surgery", Gut, 49, pp.459-461, 2001
    • (2001) Gut , vol.49 , pp. 459-461
    • Carey, H.V.1    Mangino, M.J.2    Southard, J.H.3
  • 33
    • 0034008364 scopus 로고    scopus 로고
    • Mammalian hibernation. Lessons for organ preservation
    • C. Green "Mammalian hibernation. Lessons for organ preservation", Cryo Lett., 21, pp.91-98, 2000.
    • (2000) Cryo Lett. , vol.21 , pp. 91-98
    • Green, C.1
  • 35
    • 0037116827 scopus 로고    scopus 로고
    • Liver and kidney preservation by perfusion
    • S.D. St Peter, C.J. Imber and P.J. Friend, "Liver and kidney preservation by perfusion", Lancet, 359, pp.604-613, 2002.
    • (2002) Lancet , vol.359 , pp. 604-613
    • Peter, S.D.St.1    Imber, C.J.2    Friend, P.J.3
  • 36
    • 0012921289 scopus 로고    scopus 로고
    • Hypoxie, ischemic, and reperfusion injury to liver
    • eds. I.M. Arias, J.L. Boyer, F.V. Chisari, N. Fausto, D. Schachter and D.A. Shafritz, Lippincott, Williams & Wilkins, Philadelphia
    • J.J. Lemasters, "Hypoxie, ischemic, and reperfusion injury to liver", in The Liver: Biology and Pathobiology, eds. I.M. Arias, J.L. Boyer, F.V. Chisari, N. Fausto, D. Schachter and D.A. Shafritz, Lippincott, Williams & Wilkins, Philadelphia, pp.257-279, 2001.
    • (2001) The Liver: Biology and Pathobiology , pp. 257-279
    • Lemasters, J.J.1
  • 38
    • 0035013437 scopus 로고    scopus 로고
    • Role of hepatocytes and bile duct cells in preservation-reperfusion injury of liver grafts
    • M. Kukan and P.S. Haddad, "Role of hepatocytes and bile duct cells in preservation-reperfusion injury of liver grafts", Liver Transpl., 7, pp.381 - 400, 2001.
    • (2001) Liver Transpl. , vol.7 , pp. 381-400
    • Kukan, M.1    Haddad, P.S.2
  • 39
    • 0027529364 scopus 로고
    • Role of sinusoidal lining cells in hepatic reperfusion injury following cold storage and transplantation
    • R.G. Thurman, H. Bunzendahl and J.J. Lemasters, "Role of sinusoidal lining cells in hepatic reperfusion injury following cold storage and transplantation", Semin. Liver Dis., 13, pp.93-100, 1993.
    • (1993) Semin. Liver Dis. , vol.13 , pp. 93-100
    • Thurman, R.G.1    Bunzendahl, H.2    Lemasters, J.J.3
  • 40
    • 0038567628 scopus 로고    scopus 로고
    • Protective strategies against ischemic injury of the liver
    • S. N.elzner, R. H.udiger, R. Graf and P. Clavien, "Protective strategies against ischemic injury of the liver", Gastroenterology, 125, pp.917-936, 2003.
    • (2003) Gastroenterology , vol.125 , pp. 917-936
    • Elzner, S.N.1    Udiger, R.H.2    Graf, R.3    Clavien, P.4
  • 42
    • 0033853801 scopus 로고    scopus 로고
    • Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury
    • A.B. Lentsch, A. Kato, H. Yoshidome, K.M. McMasters and M.J. Edwards, "Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury". Hepatology, 32, pp. 169-173, 2000.
    • (2000) Hepatology , vol.32 , pp. 169-173
    • Lentsch, A.B.1    Kato, A.2    Yoshidome, H.3    McMasters, K.M.4    Edwards, M.J.5
  • 43
    • 0030220572 scopus 로고    scopus 로고
    • Mechanisms of inflammatory liver injury: Adhesion molecules and cytotoxicity of neutrophils
    • H. Jaeschke, C.W. Smith, M.G. Clemens, P.E. Ganey and R.A. Roth, "Mechanisms of inflammatory liver injury: adhesion molecules and cytotoxicity of neutrophils", Toxicol. Appl. Pharmacol., 139, pp.213-226, 1996.
    • (1996) Toxicol. Appl. Pharmacol. , vol.139 , pp. 213-226
    • Jaeschke, H.1    Smith, C.W.2    Clemens, M.G.3    Ganey, P.E.4    Roth, R.A.5
  • 45
    • 11144285926 scopus 로고    scopus 로고
    • UW is superior to Celsior and HTK in the protection of human liver endothelial cells against preservation injury
    • H. Janssen, P.H. Janssen and C.E. Broelsch, "UW is superior to Celsior and HTK in the protection of human liver endothelial cells against preservation injury", Liver Transpl., 10, pp.1514-1523, 2004.
    • (2004) Liver Transpl. , vol.10 , pp. 1514-1523
    • Janssen, H.1    Janssen, P.H.2    Broelsch, C.E.3
  • 46
    • 0242552333 scopus 로고    scopus 로고
    • Effects of exogenous melatonin - A review
    • V.N. Anisimov, "Effects of exogenous melatonin - a review", Toxicologic Pathology, 31, pp.589-603, 2003.
    • (2003) Toxicologic Pathology , vol.31 , pp. 589-603
    • Anisimov, V.N.1
  • 47
    • 2942690306 scopus 로고    scopus 로고
    • Melatonin and energy homeostasis: Peripheral versus central regulation
    • P. Delagrange and R. Jockers, "Melatonin and energy homeostasis: peripheral versus central regulation", Minerva Endocrinol., 28, pp.313-320, 2003.
    • (2003) Minerva Endocrinol. , vol.28 , pp. 313-320
    • Delagrange, P.1    Jockers, R.2
  • 51
    • 2342613645 scopus 로고    scopus 로고
    • Potential therapeutic effect of antioxidant therapy in shock and inflammation
    • S. Cuzzocrea, C. Thiemermann and D. Salvemini, "Potential therapeutic effect of antioxidant therapy in shock and inflammation", Curr. Med. Chem., 11, pp.1147-1162, 2004.
    • (2004) Curr. Med. Chem. , vol.11 , pp. 1147-1162
    • Cuzzocrea, S.1    Thiemermann, C.2    Salvemini, D.3
  • 54
    • 2942625711 scopus 로고    scopus 로고
    • Melatonin and mitochondrial function
    • J. Leon, R.M. Sainz, J.C. Mayo, and D.X. Tan, "Melatonin and mitochondrial function", Life Sci., 75, pp.765-769, 2004.
    • (2004) Life Sci. , vol.75 , pp. 765-769
    • Leon, J.1    Sainz, R.M.2    Mayo, J.C.3    Tan, D.X.4
  • 55
    • 0029382404 scopus 로고
    • Permeability of pure lipid bilayers to melatonin
    • E.J.X. Costa, R.H. Lopes and M.T. Lamy-Freund, "Permeability of pure lipid bilayers to melatonin", J. Pineal Res., 19, pp.123-126, 1995.
    • (1995) J. Pineal Res. , vol.19 , pp. 123-126
    • Costa, E.J.X.1    Lopes, R.H.2    Lamy-Freund, M.T.3
  • 57
    • 0036798932 scopus 로고    scopus 로고
    • Melatonin: Localization, function, and clinical relevance
    • G.A. Bubenik, "Melatonin: localization, function, and clinical relevance", Dig. Dis. Sci., 47, pp.2336-2348, 2002.
    • (2002) Dig. Dis. Sci. , vol.47 , pp. 2336-2348
    • Bubenik, G.A.1
  • 58
    • 0035933387 scopus 로고    scopus 로고
    • Presence of melatonin in the human hepatobiliary-gastrointestinal tract
    • M. Messner, G. Huether, T. Lorf, G. Ramadori and H. Schworer, "Presence of melatonin in the human hepatobiliary-gastrointestinal tract", Life Sci., 69, pp.543-551, 2001.
    • (2001) Life Sci. , vol.69 , pp. 543-551
    • Messner, M.1    Huether, G.2    Lorf, T.3    Ramadori, G.4    Schworer, H.5
  • 61
    • 0033798633 scopus 로고    scopus 로고
    • Antioxidative effects of melatonin in protection against cellular damage caused by ionizing radiation
    • M. Karbownik and R.J. Reiter, "Antioxidative effects of melatonin in protection against cellular damage caused by ionizing radiation", Proc. Soc. Exp. Biol. Med., 225, pp.9-22, 2000.
    • (2000) Proc. Soc. Exp. Biol. Med. , vol.225 , pp. 9-22
    • Karbownik, M.1    Reiter, R.J.2
  • 62
    • 0029762091 scopus 로고    scopus 로고
    • Suppression of UV-induced erythemia by topical treatment with melatonin (N-acetyl-5-methoxytryptamine). A dose-response study
    • E. Bangha, P, Elsner and GZ. Kistlet, "Suppression of UV-induced erythemia by topical treatment with melatonin (N-acetyl-5-methoxytryptamine). A dose-response study", Arch. Dermatol. Res., 288, pp.522-526, 1996.
    • (1996) Arch. Dermatol. Res. , vol.288 , pp. 522-526
    • Bangha, E.1    Elsner, P.2    Kistlet, G.Z.3
  • 63
    • 0031816167 scopus 로고    scopus 로고
    • Topical melatonin in combination with vitamins e and C protects skin from ultraviolet-induced erythemia: A human study in vivo
    • F. Dreher, B. Gabard, D.A. Schwardt and H.I. Maibach, "Topical melatonin in combination with vitamins E and C protects skin from ultraviolet-induced erythemia: A human study in vivo", Br. J. Dermatol., 139, pp.332-339, 1998.
    • (1998) Br. J. Dermatol. , vol.139 , pp. 332-339
    • Dreher, F.1    Gabard, B.2    Schwardt, D.A.3    Maibach, H.I.4
  • 64
    • 0034940972 scopus 로고    scopus 로고
    • Melatonin reduces UV-induced reactive oxygen species in a dose-dependent manner in IL-3-stimulated leukocytes
    • T.W. Fischer, G. Acholz, B. Knoll, U.C. Hipler and P. Elsner, "Melatonin reduces UV-induced reactive oxygen species in a dose-dependent manner in IL-3-stimulated leukocytes", J. Pineal Res., 31, pp.39-45, 2001.
    • (2001) J. Pineal Res. , vol.31 , pp. 39-45
    • Fischer, T.W.1    Acholz, G.2    Knoll, B.3    Hipler, U.C.4    Elsner, P.5
  • 65
    • 0028983511 scopus 로고    scopus 로고
    • Melatonin protects human blood lymphocytes from radiation-induced chromosome damage
    • 995
    • Vijayalaxmi, R.J. Reiter and M.L. Meltz, "Melatonin protects human blood lymphocytes from radiation-induced chromosome damage", Mutat. Res., 346, pp.23-31, 995.
    • Mutat. Res. , vol.346 , pp. 23-31
    • Vijayalaxmi1    Reiter, R.J.2    Meltz, M.L.3
  • 66
    • 0029074197 scopus 로고
    • Marked reduction of radiation-induced micronuclei in human blood lymphocytes pretreated with melatonin
    • Vijayalaxmi, R.J. Reiter, E. Sewerynek, B. Poeggeler, B.Z. Leal and M.L. Meltz, "Marked reduction of radiation-induced micronuclei in human blood lymphocytes pretreated with melatonin", Radiat. Res., 143, pp.102-106, 1995.
    • (1995) Radiat. Res. , vol.143 , pp. 102-106
    • Vijayalaxmi1    Reiter, R.J.2    Sewerynek, E.3    Poeggeler, B.4    Leal, B.Z.5    Meltz, M.L.6
  • 67
    • 0029976012 scopus 로고    scopus 로고
    • Effect of melatonin on mitotic and proliferation indices and sister chromatid exchange in human blood lymphocytes
    • Vijayalaxmi, R.J. Reiter, B.Z. Leal and M.L. Meltz, "Effect of melatonin on mitotic and proliferation indices and sister chromatid exchange in human blood lymphocytes", Mutat Res, 351, pp.187-192, 1996.
    • (1996) Mutat Res , vol.351 , pp. 187-192
    • Vijayalaxmi1    Reiter, R.J.2    Leal, B.Z.3    Meltz, M.L.4
  • 68
    • 0032472921 scopus 로고    scopus 로고
    • Melatonin reduces gamma radiation-induced primary DNA damage in human blood lymphocytes
    • Vijayalaxmi, R.J. Reiter, T.S. Herman and M.L. Meltz, "Melatonin reduces gamma radiation-induced primary DNA damage in human blood lymphocytes", Mutat. Res., 397, pp.203-208, 1998.
    • (1998) Mutat. Res. , vol.397 , pp. 203-208
    • Vijayalaxmi1    Reiter, R.J.2    Herman, T.S.3    Meltz, M.L.4
  • 69
    • 0031714160 scopus 로고    scopus 로고
    • Modulatory effects of melatonin on genotoxic response of reference mutagens in the Ames test and the comet assay
    • S.A. Musatov, V.N. Anisimov, V. Andre, C. Vigreux, T. Godard, P. Gauduchon and F. Sichel, "Modulatory effects of melatonin on genotoxic response of reference mutagens in the Ames test and the comet assay", Mutat Res., 417, pp.75-84, 1998.
    • (1998) Mutat Res. , vol.417 , pp. 75-84
    • Musatov, S.A.1    Anisimov, V.N.2    Andre, V.3    Vigreux, C.4    Godard, T.5    Gauduchon, P.6    Sichel, F.7
  • 70
    • 0032872264 scopus 로고    scopus 로고
    • Radioprotective effect of melatonin assayed by measuring chromosomal damage in mitotic and meiotic cells
    • F.M. Badr, O.H.M. Habit and M.M. Harraz, "Radioprotective effect of melatonin assayed by measuring chromosomal damage in mitotic and meiotic cells". Mutat. Res., 444, pp.367-372, 1999.
    • (1999) Mutat. Res. , vol.444 , pp. 367-372
    • Badr, F.M.1    Habit, O.H.M.2    Harraz, M.M.3
  • 71
    • 0026412296 scopus 로고
    • Morphometric aspects of seminiferous tubules in rats treated with melatonin and whole body irradiation
    • Z. Mornjakovic, M. Scepovic and Z. Kundurovic, "Morphometric aspects of seminiferous tubules in rats treated with melatonin and whole body irradiation", Med. Arch., 45, pp.9-10, 1991.
    • (1991) Med. Arch. , vol.45 , pp. 9-10
    • Mornjakovic, Z.1    Scepovic, M.2    Kundurovic, Z.3
  • 72
    • 0032250811 scopus 로고    scopus 로고
    • Morphometric characteristics of Leydig cells after total body irradiation of rats treated with melatonin
    • Z. Mornjakovic, S. Alicelebic, N. Bilalovic and I.Susko "Morphometric characteristics of Leydig cells after total body irradiation of rats treated with melatonin", Med. Arch., 52, pp.183-184, 1998.
    • (1998) Med. Arch. , vol.52 , pp. 183-184
    • Mornjakovic, Z.1    Alicelebic, S.2    Bilalovic, N.3    Susko, I.4
  • 73
    • 0032945370 scopus 로고    scopus 로고
    • G-radiation accelerates follicular atresia in immature mice
    • J.K. Kim, C.J. Lee, K.W. Son, and Y.D. Yoon, "g-radiation accelerates follicular atresia in immature mice", In Vivo, 23, pp.21-24, 1999.
    • (1999) Vivo , vol.23 , pp. 21-24
    • Kim, J.K.1    Lee, C.J.2    Son, K.W.3    Yoon, Y.D.4
  • 74
    • 0343527385 scopus 로고    scopus 로고
    • Effect of exogenous melatonin on the ovarian follicles in irradiated mouse
    • J.K. Kim and C.J. Lee, "Effect of exogenous melatonin on the ovarian follicles in irradiated mouse", Mutat. Res., 449, pp.33-39, 2000.
    • (2000) Mutat. Res. , vol.449 , pp. 33-39
    • Kim, J.K.1    Lee, C.J.2
  • 75
    • 0024848267 scopus 로고
    • Histoenzymological reactions of the thyroid gland in irradiated and previously melatonin untreated irradiated rats
    • Z. Kundurovic and M. Scepovic, "Histoenzymological reactions of the thyroid gland in irradiated and previously melatonin untreated irradiated rats", Acta Med. Jugosl., 43, pp.337-347, 1989.
    • (1989) Acta Med. Jugosl. , vol.43 , pp. 337-347
    • Kundurovic, Z.1    Scepovic, M.2
  • 76
    • 0027026082 scopus 로고
    • Morphometric characteristics of thyroid cells in irradiation-stressed rats treated with pinealectomy and melatonin
    • Z. Kundurovic and Z. Mornjakovic, "Morphometric characteristics of thyroid cells in irradiation-stressed rats treated with pinealectomy and melatonin", Med. Arch., 46, pp.9-10, 1992.
    • (1992) Med. Arch. , vol.46 , pp. 9-10
    • Kundurovic, Z.1    Mornjakovic, Z.2
  • 77
    • 0033798101 scopus 로고    scopus 로고
    • Protective effects of melatonin against oxidation of guanine bases in DNA and decreased microsomal membrane fluidity in rat liver induced by whole body ionizing radiation
    • M. Karbownik, R.J. Reiter, W. Qi, J.J. Garcia, D.X. Tan, L.C. Manchester and Vijayalaxmi, "Protective effects of melatonin against oxidation of guanine bases in DNA and decreased microsomal membrane fluidity in rat liver induced by whole body ionizing radiation", Mol. Cell. Biochem., 211, pp.137-144, 2000.
    • (2000) Mol. Cell. Biochem. , vol.211 , pp. 137-144
    • Karbownik, M.1    Reiter, R.J.2    Qi, W.3    Garcia, J.J.4    Tan, D.X.5    Manchester, L.C.6    Vijayalaxmi7
  • 79
    • 0029793307 scopus 로고    scopus 로고
    • Oxidative damage in the liver induced by ischemia-reperfusion: Protection by melatonin
    • E. Sewerynek, R.J. Reiter, D. Melchiorri, G.G Ortiz. and A. Lewinski, "Oxidative damage in the liver induced by ischemia-reperfusion: protection by melatonin", Hepatogastroenterology, 43, pp.898-905, 1996.
    • (1996) Hepatogastroenterology , vol.43 , pp. 898-905
    • Sewerynek, E.1    Reiter, R.J.2    Melchiorri, D.3    Ortiz, G.G.4    Lewinski, A.5
  • 80
    • 0034781638 scopus 로고    scopus 로고
    • Effect of exogenous melatonin on hepatic energetic status during ischemia/reperfusion: Possible role of tumor necrosis factor-alpha and nitric oxide
    • S. Rodriguez-Reynoso, C. Leal, E. Portilla, N. Olivares and J.J. Muniz, "Effect of exogenous melatonin on hepatic energetic status during ischemia/reperfusion: possible role of tumor necrosis factor-alpha and nitric oxide", Surg. Res., 100, pp.141-149, 2001.
    • (2001) Surg. Res. , vol.100 , pp. 141-149
    • Rodriguez-Reynoso, S.1    Leal, C.2    Portilla, E.3    Olivares, N.4    Muniz, J.J.5
  • 81
    • 33644905199 scopus 로고    scopus 로고
    • Melatonin limits ischemia-reperfusion injury: Implications for aging and organ transplantation
    • ed. M. Karasek, Nova Science Publishers, New York., (in press)
    • R.J Reiter., D.-X. Tan, M. Vairetti, M.D. Maldonado and I. Freitas, "Melatonin limits ischemia-reperfusion injury: implications for aging and organ transplantation", In: Aging and Age-related Diseases: The Basics, ed. M. Karasek, Nova Science Publishers, New York., 2005 (in press).
    • (2005) Aging and Age-related Diseases: The Basics
    • Reiter, R.J.1    Tan, D.-X.2    Vairetti, M.3    Maldonado, M.D.4    Freitas, I.5
  • 82
    • 22844452666 scopus 로고    scopus 로고
    • Exogenous melatonin enhances bile flow and ATP levels after cold storage and reperfusion in rat liver: Implications for liver transplantation
    • M. Vairetti, A. Ferrigno, R. Bertone, V. Rizzo, P. Richelmi, F Berté, R.J. Reiter and I. Freitas, "Exogenous melatonin enhances bile flow and ATP levels after cold storage and reperfusion in rat liver: implications for liver transplantation", J. Pineal Res., 38, pp.223-230, 2005.
    • (2005) J. Pineal Res. , vol.38 , pp. 223-230
    • Vairetti, M.1    Ferrigno, A.2    Bertone, R.3    Rizzo, V.4    Richelmi, P.5    Berté, F.6    Reiter, R.J.7    Freitas, I.8
  • 83
    • 0030983191 scopus 로고    scopus 로고
    • In situ detection of spontaneous superoxide anion and singlet oxygen production by mitochondria in rat liver and small intestine
    • E.D. Kerver, I.M. Vogels, K.S. Bosch, H. Vreeling-Sindelarova, R.J. Van den Munckhof, W.M. Frederiks, "In situ detection of spontaneous superoxide anion and singlet oxygen production by mitochondria in rat liver and small intestine", Histochem. J., 29, pp.229-237, 1997.
    • (1997) Histochem. J. , vol.29 , pp. 229-237
    • Kerver, E.D.1    Vogels, I.M.2    Bosch, K.S.3    Vreeling-Sindelarova, H.4    Van Den Munckhof, R.J.5    Frederiks, W.M.6
  • 84
    • 0036163790 scopus 로고    scopus 로고
    • In situ detection of reactive oxygen species and nitric oxide production in normal and pathological tissues: Improvement by differential interference contrast
    • I. Freitas, P. Griffini, V. Bertone, R. Bertone, C. Fenoglio, R. Milliery and M. Vairetti, "In situ detection of reactive oxygen species and nitric oxide production in normal and pathological tissues: improvement by differential interference contrast", Exp. Gerontol., 37, pp.591-602, 2002.
    • (2002) Exp. Gerontol. , vol.37 , pp. 591-602
    • Freitas, I.1    Griffini, P.2    Bertone, V.3    Bertone, R.4    Fenoglio, C.5    Milliery, R.6    Vairetti, M.7
  • 85
    • 0033960898 scopus 로고    scopus 로고
    • Oxygen: Modulator of metabolic zonation and disease of the liver
    • K. Jungermann and T. Kietzmann, "Oxygen: modulator of metabolic zonation and disease of the liver", Hepatology, 31, pp.255-260, 2000.
    • (2000) Hepatology , vol.31 , pp. 255-260
    • Jungermann, K.1    Kietzmann, T.2
  • 87
    • 0141646551 scopus 로고    scopus 로고
    • Melatonin attenuates the sympathetic nerve responses to orthostatic stress in humans
    • C.A. Ray, "Melatonin attenuates the sympathetic nerve responses to orthostatic stress in humans", J. Physiol., 551, pp.1043-1048, 2003.
    • (2003) J. Physiol. , vol.551 , pp. 1043-1048
    • Ray, C.A.1


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