Orthostatic intolerance after spaceflight

Journal of Applied Physiology

Volumn 81, Issue 1, 1996, Pages 7-18

  Buckey Jr , Jay C ^a,b   Lane, Lynda D ^a   Levine, Benjamin D ^a,c   Watenpaugh, Donald E ^a,d   Wright, Sheryl J ^a   Moore, Willie E ^a   Gaffney, F Andrew ^a,e   Blomqvist, C Gunnar ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^c Institute for Exercise and Environmental Medicine Dallas   (United States)

^d NASA AMES RESEARCH CENTER   (United States)

^e VANDERBILT UNIVERSITY   (United States)

Author keywords

orthostatic hypotension; syncope

Indexed keywords

ADULT; ARTICLE; BODY POSTURE; COSMONAUT; FEMALE; HEART OUTPUT; HEART STROKE VOLUME; HEMODYNAMIC MONITORING; HUMAN; HUMAN EXPERIMENT; MALE; MEAN ARTERIAL PRESSURE; NORMAL HUMAN; ORTHOSTATIC HYPOTENSION; PRIORITY JOURNAL; SPACE FLIGHT; SYNCOPE; SYSTOLIC BLOOD PRESSURE;

EID: 0030038559     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1996.81.1.7     Document Type: Article

References (34)

1. Abboud, F. Ventricular syncope. Is the heart a sensory organ? N. Engl. J. Med. 320: 390-392, 1989.
2. Beck, L., F. Baisch, F. A. Gaffney, J. C. Buckey, P. Arbeille, F. Patat, A. D. J. Ten Harkel, A. Hillebrecht, H. Schulz, J. M. Karemaker, M. Meyer, and C. G. Blomqvist. Cardiovascular response to lower body negative pressure before, during and after ten days head-down tilt bedrest. Acta Physiol. Scand. 144, Suppl. 604: 43-52, 1992.
3. Blomqvist, C. G. Orthostatic intolerance. In: Cardiology, edited by W. W. Parmley and K. Chatterjee. Philadelphia, PA: Lippincott, 1990, p. 1-37.
4. Blomqvist, C. G., and H. L. Stone. Cardiovascular adjustments to gravitational stress. In: Handbook of Physiology. The Cardiovascular System. Peripheral Circulation and Organ Blood Flow. Bethesda, MD: Am. Physiol. Soc., 1983, sect. 2, vol. III, pt. 2, chapt. 28, p. 1025-1063.
5. Buckey, J. C., R. L. Goble, and C. G. Blomqvist. A new device for continuous ambulatory central venous pressure measurement. Med. Instrum. 21: 238-243, 1987.
6. Buckey, J. C., L. D. Lane, G. Plath, F. A. Gaffney, F. Baisch, and C. G. Blomqvist. Effects of head-down tilt for 10 days on the compliance of the leg. Acta Physiol. Scand. 144, Suppl. S604: 53-60, 1992.
7. Bungo, M. W., J. B. Charles, and P. C. Johnson, Jr. Cardiovascular deconditioning during space flight and the use of saline as a countermeasure to Orthostatic intolerance. Aviat. Space Environ. Med. 56: 985-990, 1985.
8. Charles, J. B., and M. M. Jones. Cardiovascular Orthostatic function of space shuttle astronauts during and after return from orbit. Congr. Int. Astronaut. Fed. 43rd Paris, France 1992, p. 1-7. (International Astronautical Federation/International Astronautical Association Reprint 92-0262)
9. Convertino, V. A., D. F. Doerr, and S. L. Stein. Changes in the size and compliance of the calf after 30 days of simulated microgravity. J. Appl. Physiol. 66: 1509-1512, 1989.
10. Fritsch, J. M., J. B. Charles, B. S. Bennett, M. M. Jones, and D. L. Eckberg. Short-duration spaceflight impairs human carotid baroreceptor-cardiac reflex responses. J. Appl. Physiol. 73: 664-671, 1992.
11. Fritsch-Yelle, J. M., J. B. Charles, M. M. Jones, L. A. Beightol, and D. L. Eckberg. Spaceflight alters autonomic regulation of arterial pressure in humans. J. Appl. Physiol. 77: 1776-1783, 1994.
12. Gaffney, F. A., E. R. Thal, W. F. Taylor, B. C. Bastian, J. A. Weigelt, J. M. Atkins, and C. G. Blomqvist, Hemodynamic effects of medical anti-shock trousers (MAST garment). J. Trauma 21: 931-937, 1981.
13. Hainsworth, R. Syncope and fainting. In: Autonomic Failure: A Textbook of Clinical Disorders of the Autonomic Nervous System (3rd ed.), edited by R. Bannister and C. J. Mathias. New York: Oxford Medical Publications, 1992, chapt. 39, p. 761-781.
14. Johnson, P. C., T. B. Driscoll, and A. D. LeBlanc. Blood volume changes. In: Biomedical Results from Skylab, edited by R. S. Johnston and L. F. Dietlein. Washington, DC:0 NASA, 1977, p. 235-241. (NASA Spec. Rep. SP-733)
15. Jones, M. M., and J. B. Charles. Human blood pressure and heart rate changes during space shuttle landing and crew egress (Abstract). FASEB J. 7: A665, 1993.
16. Levine, B. D. Regulation of central blood volume and cardiac filling in endurance athletes: the Frank-Starling mechanism as a determinant of orthostatic tolerance. Med. Sci. Sports Exercise 25: 727-732, 1993.
17. Levine, B. D., J. C. Buckey, D. B. Friedman, L. D. Lane, D. E. Watenpaugh, and C. G. Blomqvist. Right atrial pressure (RA) vs. pulmonary capillary wedge pressure (PCW) in normal man (Abstract). Circulation 80, Suppl. 2: II-250, 1989.
18. Levine, B. D., C.A. Giller, L. D. Lane, J. C. Buckey, and C. G. Blomqvist. Cerebral versus systemic hemodynamics during graded orthostatic stress in humans. Circulation 90: 298-306, 1994.
19. Levine, B. D., L. D. Lane, F. A. Gaffney, J. C. Buckey, and C. G. Blomqvist. Maximal exercise performance after adaptation to microgravity (Abstract). Med. Sci. Sports Exercise 26, Suppl. 5: S112, 1994.
20. Mulvagh, S. L., J. B. Charles, J. M. Riddle, T. L. Rehbein, and M. W. Bungo. Echocardiographic evaluation of the cardiovascular effects of short-duration spaceflight. J. Clin. Pharmacol. 31: 1024-1026, 1991.
21. Pawelczyk, J. A., R. Query, J. Zuckerman, S. B. McMinn, and P. B. Raven. Sympathetic activation with abdominal compression: a mechanism for the action medical anti-shock trousers (Abstract). FASEB J. 8: A604, 1994.
22. Pool, S. L., R. D. Billica, and J. B. Charles. Medical risk assessment for space shuttle missions. Proc. IAA Man in Space Symposium 10th Paris France 1993, p. 20. (International Astronautical Association Preprint T-0303)
23. Pool, S. L., A. E. Nicogossian, E. C. Moseley, J. J. Uri, and L. J. Pepper. Medical evaluations for astronaut selection and longitudinal studies. In: Space Physiology and Medicine (3rd ed.), edited by A. Nicogossian. Philadelphia, PA: Lea & Febiger, 1994, p. 375-393.
24. Prisk, G. K., H. J. B. Guy, A. R. Elliot, R. A. Deutsehman, and J. B. West. Pulmonary diffusing capacity, capillary blood volume, and cardiac output during sustained microgravity. J. Appl. Physiol. 75: 15-26, 1993.
25. Raven, P. B., M. Saito, F. A. Gaffney, J. Schutte, and C. G. Blomqvist. Interactions between surface cooling and LBNP-induced central hypovolemia. Aviat. Space Environ. Med. 51: 497-503, 1980.
26. Rowell, L. B. The venous system. In: Human Circulation: Regulation During Physical Stress. New York: Oxford Univ. Press, 1986, chapt. 3, p. 44-77.
27. Sutton, R. Vasodepressor syncope. Herz 18: 155-163, 1993.
28. Thornton, W., V. Hedge, E. Coleman, J. Uri, and T. Moore. Changes in leg volumes during microgravity simulation. Aviat. Space Environ. Med. 63: 789-794, 1992.
29. Triebwasser, J. H., R. L. Johnson, R. P. Burpo, J. C. Campbell, W. C. Reardon, and C. G. Blomqvist. Noninvasive determination of cardiac output by a modified acetylene rebreathing procedure utilizing mass spectrometer measurements. Aviat. Space Environ. Med. 48: 203-209, 1977.
30. Udden, M. M., T. B. Driscoll, M. H. Pickett, C. S. Leach-Huntoon, and C. P. Alfrey. Decreased production of red blood cells in human subjects exposed to microgravity. J. Lab. Clin. Med. 125: 442-449, 1995.
31. Watenpaugh, D. E., J. C. Buckey, L. D. Lane, F. A. Gaffney, W. E. Moore, B. D. Levine, S. J. Wright, and C. G. Blomqvist. Human leg blood flow and compliance during spaceflight (Abstract). Am. Soc. Gravitat. Space Biol. Bull. 6: 35, 1992.
32. Whinnery, J. E. +Gz tolerance correlation with clinical parameters. Aviat. Space Environ. Med. 50: 736-741, 1979.
33. Whitson, P. A., J. B. Charles, W. J. Williams, and M. Cintión. Changes in sympathoadrenal response to standing in humans after spaceflight. J. Appl. Physiol. 79: 428-433, 1995.
34. Young, L. R., C. M. Oman, D. G. Watt, K. E. Money, B. K. Lichtenberg, R. V. Kenyon, and A. P. Arrott. M. I. T./Canadian vestibular experiments on the Spacelab-1 mission: 1. Sensory adaptation to weightlessness and readaptation to one-g: an overview. Exp. Brain Res. 64: 291-298, 1986.