Immunohistochemical analysis of platelet-derived growth factor and basic fibroblast growth factor in cardiac biopsy and autopsy specimens of heart transplant patients

American Journal of Cardiology

Volumn 77, Issue 14, 1996, Pages 1210-1215

  Shaddy, Robert E ^a,b   Hammond, Elizabeth H ^a   Yowell, Robert L ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b PRIMARY CHILDREN'S MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR;

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOPSY; GRAFT FAILURE; GRAFT REJECTION; HEART MUSCLE BIOPSY; HEART MUSCLE ISCHEMIA; HEART TRANSPLANTATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; PREVALENCE; PRIORITY JOURNAL; SCHOOL CHILD; VASCULAR DISEASE;

EID: 0029948991     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(96)00164-6     Document Type: Article

References (29)

1. O'Neill BJ, Pflugfelder PW, Singh NR, Menkis AH, McKenzie FN, Kostuk WJ, Frequency of angiographic detection and quantitative assessment of coronary arterial disease one and three years after cardiac transplantation. Am J Cardiol 1989;63:1221-1226.
2. Hosenpud JD, Shipley GD, Wagner CR. Cardiac allograft vasculopathy: current concepts, recent developments, and future directions. J Heart Lung Transplant 1992:11:9-23.
3. Miller LW. Allograft vascular disease: a disease not limited to hearts. J Heart Lung Transplant 1992;11:S32-S37.
4. Ross RR, Raines EW, Bowen-Pope DF. The biology of platelet-derived growth factor. Cell 1986;46:155-169.
5. Harlan JM, Thompson RL, Ross RR, Bowen-Pope DF. Alpha-thrombin induces release of platelet-derived growth factor-like molecules by cultured endothelial cells. J Cell Biol 1986;103:1129-1133.
6. Raines EW, Dower SK, Ross R. Interleukin-1 activity for fibroblasts and smooth muscle cells is due to PDGF-AA. Science 1989;243:393-396.
7. Hajjar KA, Hajjar DP, Silverstein RL, Nachman RL. Tumor necrosis-mediated release of platelet-derived growth factor from cultured endothelial cells. J Exp Med 1987;66:235-245.
8. Bradham DM, Igarashi A, Potter RL, Grotendorst GR. Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10. J Cell Biol 1991;114:1285-1294.
9. Libby P, Warner SJC, Salomon RN, Birinyi LK. Production of platelet-derived growth factor-like mitogen by smooth-muscle cells from human atheroma. N Engl J Med 1988;318:1493-1498.
10. Ross R, Masuda J, Raines E, Gown AM, Katsuda S, Sasahara M, Maiden LT, Masuko H, Sato H. Localization of PDGF-B protein in macrophages in all phases of atherogenesis. Science 1990;248:1009-1012.
11. Rubin K, Hansson GK, Ronnstrand L, Claesson-Welch L, Fellstrom B, Tingstrom A, Lanson E, Klareskog L, Heldin C-H, Terracio L. Induction of B-type receptors for platelet-derived growth factor in vascular inflammation: possible implications for development of vascular proliferative lesions. Lancet 1988;1:1353-1359.
12. Higgy NA, Davidoff AW, Grothman GT, Hollenberg MD, Benediktsson H, Paul LC. Expression of platelet-derived growth factor receptor in rat heart allografts. J Heart Lung Transplant 1991;10:1012-1022.
13. Gospodarowicz D, Neufeld G, Schweigerer L. Fibroblast growth factor: structural and biological properties. J Cell Physiol 1987;5(suppl):15-26.
14. Gordon D. Growth factors and cell proliferation in human transplant arteriosclerosis. J Heart Lung Transplant 1992;11:S7.
15. Schoen FJ, Libby P. Cardiac transplant graft arteriosclerosis. Trends Cardiovasc Med 1991;1:216-223.
16. Salomon RN, Hughes CCW, Schoen FJ, Payne DD, Pober JS, Libby P. Human coronary transplantation-associated arteriosclerosis. Am J Pathol 1991;138:791-798.
17. Kottke-Marchant K, Newman WE, Ratliff NB. Cardiac transplant-associated vascular disease: evolution, immunophenotype, and evidence of endothelial activation. Cardiovasc Pathol 1992;1:177-188.
18. Gadjusek C, Carbon S. Injury-induced release of basic fibroblast growth factor from bovine aortic endothelium. J Cell Physiol 1989;139:570-579.
19. Billingham ME, Cary NRB, Hammond EH, Kemnitz J, Marboe C, McAllister HA, Snovar DC, Winters GL, Zerbe A. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart Rejection Study Group. J Heart Transplant 1990;9:587-593.
20. Hammond EH, Yowell RL, Nunoda S, Menlove RL, Renlund DG, Bristow MR, Gay WA, Jones KW, O'Connell JB. Vascular (humoral) rejection in heart transplantation: pathologic observations and clinical implications. J Heart Transplant 1989;8:430-443.
21. Reilly TM, Taylor DS, Herblin WF, Thoolen MJ, Chiu AT, Watson DW, Timmermans PB. Monoclonal antibodies directed against basic fibroblast growth factor which inhibit its biological activity in vitro and in vivo. Biochem Biophys Res Commun 1989;164:736-743.
22. Hammond EH, Hansen JK, Spencer LS, Jensen A, Yowell RL. Immunofluorescence on endomyocardial biopsy specimens: methods and interpretation. J Heart Lung Transplant 1993;12:S113-S124.
23. Carlquist JF, Hammond EH, Yowell RL, O'Connell JB, Anderson JL. Correlation between class II antigen (DR) expression and interleukin-2-induced lymphocyte proliferation during acute cardiac allograft rejection. Transplantation 1990;50:582-588.
24. Gesualdo L, Pinzani M, Floriano JJ, Hassan MO, Nagy NU, Schena FP, Emancipator SN, Abboud HE. Platelet-derived growth factor expression in mesangial proliferative glomerulonephritis. Lab Invest 1991;65:160-167.
25. Cordon-Cardo C. Vlodavsky I, Haimovitz-Friedman A, Hicklin D, Fuks Z. Expression of basic fibroblast growth factor in normal human tissues. Lab Invest 1990;63:832-839.
26. Kardami E, Fandrich RR. Basic fibroblast growth factor in atria and ventricles of vertebrate heart. J Cell Biol 1989;109:1865-1875.
27. Vlodavsky I, Fridman R, Sullivan R, Sasse J, Klagsbrun M. Aortic endothelial cells synthesize basic fibroblast growth factor which remains cell-associated and platelet-derived growth factor which is secreted. J Cell Physiol 1987;131:402-408.
28. Hammond EH, Hansen JK, Spencer LS, Jensen A, Riddell D, Craven CM, Yowell RL. Vascular rejection in cardiac transplantation: histologic, immunopathologic, and ultrastructural features. Cardiovasc Pathol 1993;2:21-34.
29. Zhao X-M, Yeoh T-K, Frist WH, Porterfield DL, Miller GG. Induction of acidic fibroblast growth factor and full-length platelet-derived growth factor expression in human cardiac allografts. Circulation 1994;90:677-685.