Complement mediated cell death is associated with DNA fragmentation

Cell Death and Differentiation

Volumn 7, Issue 1, 2000, Pages 48-58

  Cragg, M S ^a   Howatt, W J ^a   Bloodworth, L ^a   Anderson, V A ^a   Morgan, B P ^b   Glennie, M J ^a  

^a UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Apoptosis; Cell death; Complement; DNA fragmentation; DNases

Indexed keywords

COMPLEMENT; COMPLEMENT MEMBRANE ATTACK COMPLEX; DNA FRAGMENT;

APOPTOSIS; ARTICLE; CHROMATIN CONDENSATION; COMPLEMENT ACTIVATION; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; DNA DEGRADATION; ELECTRON MICROSCOPY; HUMAN; HUMAN CELL; MEMBRANE PERMEABILITY; NICK END LABELING; NUCLEOSOME; PRIORITY JOURNAL; SERUM;

EID: 0034019873     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400627     Document Type: Article

References (48)

1. Kerr JFR, Wyllie AH and Currie AR (1972) Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J. Cancer. 26: 239-257
2. Hughes MF and Cidlowski JA (1996) Enzymology of apoptosis. In Apoptosis in normal development and cancer, Sluyser M, ed (London: Taylor and Francis Press Ltd) pp. 20-31
3. Wyllie AH, Kerr JFR and Currie AR (1980) Cell Death: the significance of apoptosis. Intl. Rev. Cytol. 68: 251-306
4. Umansky SH (1996) Apoptosis: molecular and cellular mechanisms: A review. Mol. Biol. 30: 285-295
5. Kerr JFR, Winterford CM and Harmon BV (1994) Apoptosis: its significance in cancer and cancer therapy. Cancer. 73: 2013-2026
6. Kerr JFR and Harmon BV (1991) Definition and incidence of apoptosis: an historical perspective. In Apoptosis: the Molecular Basis of Cell Death, Tomei LD and Cope OF, eds. (New York: Cold Spring Harbor Laboratory Press) pp. 5-29
7. Darzynkiewicz Z, Juan G, Li X, Gorczyca W, Murakami T and Traganos F (1997) Cytometry in cell Necrobiology: analysis of apoptosis and accidental cell death (necrosis). Cytometry 27: 1-20
8. Arends MJ, Morris RG and Wyllie AH (1990) Apoptosis: the role of the endonuclease. Am. J. Pathol. 136: 593-608
9. Ishigami T, Kim KM, Horiguchi Y, Higaki Y, Hata D, Heike T, Katamura K, Mayumi M and Mikawa H (1992) Anti-IgM antibody-induced cell death in a human B lymphoma cell line, B104, represents a novel programmed cell death. J. Immunol. 148: 360-368
10. Matsuoka S, Asano Y, Sano K, Kishimoto I, Yorifuji H, Utsuyama M, Hirokavita K and Tada T (1995) A novel type of cell-death of lymphocytes induced by a monoclonal antibody without participation of complement. J. Exp. Med. 181: 2007-2015
11. Bhat NM, Bieber MM, Stevenson FK and Teng NNH (1996) Rapid cytotoxicity of human B lymphocytes induced by VH4-34 (VH4.21) gene-enccded monoclonal antibodies. Clin. Exp. Immunol. 105: 1-8
12. Hagar H, Ueda N and Shah SV (1997) Tyrosine phosphorylation in DNA damage and cell death in hypoxic injury to LLC-PK1 cells. Kidney Intl. 51: 1747-1753
13. Papadimitriou JC, Drachenberg CB, Shin ML and Trump BF (1994) Ultrastructural studies of complement mediated cell death: a biological reaction model to plasma membrane injury. Virch. Arch. 424: 677-685
14. Kim SH, Carney DF, Papadimitriou JC and Shin ML (1989) Effect of osmotic protection on nucleated cell killing by C5b-9: Cell death is not affected by the prevention of cell swelling. Mol. Immunol. 26: 323-331
15. Green HR, Barrow P and Goldberg B (1959) Effect of antibody and complement on permeability control in ascites tumour cells and erythrocytes. J. Ex. Med. 110: 699-713
16. Shipley WU, Baker AR and Colten HR (1971) DNA degradation in mammalian cells following complement-mediated cytolysis. J. Immunol. 106: 576-579
17. Nicoletti I, Migliorati G, Pagliacci MC, Grignani F and Riccardi C (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Meths. 139: 271-279
18. Gold R, Schmied M, Giegerich G, Breitschopf H, Hartung HP, Toyka KV and Lassman H (1994) Differentiation between cellular apoptosis and necrosis by the combined use of in-situ tailing and nick translation techniques. Lab. Invest. 71: 219-225
19. 2+ induced by antibody plus complement. FEBS. Lett. 107: 55-60
20. Campbell AK, Daw RA, Hallett MB and Luzio JP (1981) Direct measurement of the increase in intracellular free calcium ion concentration in response to the action of complement. Biochem. J. 194: 551-560
21. 2+ on the lytic process. J. Immunol. 138: 1530-1536
22. Gaido ML and Cidlowski JA (1991) Identification, purification and characterisation of a calcium-dependent endonuclease (NUC18) from apoptotic rat thymocytes. J. Biol. Chem. 266: 18580-18585
23. Peitsch MC, Hesterkamp T, Polzar B, Mannherz HG and Tschopp J (1992) Functional characterisation of serum DNase 1 in MRL-lpr/lpr mice. Biochem. Biophys. Res. Commun. 186: 739-745
24. Wyllie AH (1980) Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 284: 555-556
25. Wyngaarden JB and Smith LH (1988) Cecil Textbook of Medicine (Philadelphia: W.B. Saunders Company) pp. 2395
26. Peitsch MC, Mannherz HG and Tschopp J (1994) The apoptosis endonucleases: cleaning up after cell death? Trends Cell Biol. 4: 37-41
27. Kishi K, Yasuda T, Ikehara Y, Sawazaki K, Sato W and Iida R (1990) Human serum deoxyribonuclease 1 (DNase I) polymorphism: Pattern similarities among isozymes from serum, urine, kidney, liver and pancreas. Am. J. Hum. Genet. 47: 121-126
28. Love JD and Hewitt RR (1979) The relationship between human serum and human pancreatic DNase I. J. Biol. Chem. 254: 12588-12594
29. Paddenberg R, Wulf S, Weber A, Heimann P, Beck L and Mannherz HG (1996) Internucleosomal DNA fragmentation in cultured cells under conditions reported to induce apoptosis may be caused by mycoplasma endonucleases. Eur. J. Cell Biol. 71: 105-119
30. Lacks SA (1981) Deoxyribonuclease 1 in mammalian tissues - specificity of inhibition by actin. J. Biol. Chem. 256: 2644-2648
31. Shack J (1957) Deoxyribonucleases of mouse tissues. J. Biol. Chem. 226: 573-581
32. Herriot RM, Connolly JH and Gupta S (1961) Blood nucleases and infectious viral nucleic acids. Nature 189: 817-820
33. Polzar B and Mannherz HG (1990) Nucleotide sequence of a full length cDNA clone encoding the deoxyribonuclease 1 from the rat parotid gland. Nuc. Acids Res. 18: 7151
34. Sakahira H, Enari M and Nagata S (1998) Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391: 96-99
35. Booth C and Koch GL (1989) Perturbation of cellular calcium induces secretion of luminal ER proteins. Cell 59: 729-737
36. Henkart PA (1985) Mechanism of lymphocyte-mediated cytotoxicity. Ann. Rev. Immunol. 3: 31-58
37. Lowrey DM, Aebischer T, Olsen KJ, Lichtenhelf M, Rupp F, Hentgartner H and Podack ER (1989) Cloning, analysis and expression of murine perforin 1 cDNA, a component of cytotoxic T-cell granules with homology to complement component C9. Proc. Natl. Acad. Sci. U.S.A. 86: 247-251
38. Selsted ME and Oullette AJ (1995) Defensins in granules of phagocytic and nonphagocytic cells. Trends Cell Biol. 5: 114-119
39. Collins RJ, Harmon BV, Gobe GC and Kerr JFR (1992) Internucleosomal DNA cleavage should not be the sole criterion for identifying apoptosis. Intl. J. Radiat. Biol. 61: 451-453
40. Peitsch MC, Muller C and Tschopp J (1993) DNA fragmentation during apoptosis is caused by frequent single-strand cuts. Nucl. Acids Res. 18: 4206-4209
41. Chitrabamrung S, Rubin RL and Tan EM (1981) Serum deoxyribonuclease-1 and clinical activity in systemic lupus erythematosus. Rheumatol. Int. 1: 55-60
42. Matsui H, Tsuji S, Nishimura H and Nagasawa S (1994) Activation of the alternative pathway of complement by apoptotic Jurkat cells. FEBS Lett. 351: 419-422
43. Tsuji S, Kaji K and Nagasawa S (1994) Activation of the alternative pathway of human complement by apoptotic human umbilical vein endothelial cells. J. Biochem. 116: 794-800
44. Botto M, DellAgnola C, Bygrave AE, Thompson EM, Cook HT, Retry F, Loos M, Pandolfi PP and Walport MJ (1998) Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nature Genet. 19: 56-59
45. Abraha A, Morgan BP and Luzio JP (1988) The preparation and characterisation of monoclonal antibodies to human complement component C8 and their use in purification of C8 and C8 subunits. Biochem. J. 251: 285-292
46. Clark EA, Shu G and Ledbetter JA (1985) Role of the Bp35 cell surface polypeptide in human B-cell activation. Proc. Natl. Acad. Sci. U.S.A. 82: 1766-1770
47. 3 antibody derivatives. In Tumour Immunobiology, a Practical Approach, Rees RC, Reynolds CW, eds. (Oxford: Oxford University Press) pp. 225-244
48. Nieto MA and Lopez-Rivas A (1989) IL-2 protects T lymphocytes from glucocorticoid-induced DNA fragmentation and cell death. J. Immunol. 143: 4166-4170