Comparative pharmacokinetics of [14C]metosulam (N-[2,6-dichloro-3-methylphenyl]-5,7-dimethoxy-1,2,4- triazolo-[1,5α]-pyrimidine-2-sulfonamide) in rats, mice and dogs

Journal of Applied Toxicology

Volumn 17, Issue 1, 1997, Pages 9-21

  Timchalk, C ^a   Dryzga, M D ^a   Johnson, K A ^a   Eddy, S L ^a   Freshour, N L ^a   Kropscott, B E ^a   Nolan, R J ^a  

^a DOW CHEMICAL COMPANY   (United States)

Author keywords

Comparative sciences; Dog; Metabolism; Metosulam; Mouse; Pharmacokinetics; Rat

Indexed keywords

HERBICIDE; METOSULAM; SULFONAMIDE; UNCLASSIFIED DRUG; CARBON; PYRIMIDINE DERIVATIVE; TRIAZOLE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOG; HUMAN EXPERIMENT; MALE; MOUSE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE; TOXICOKINETICS; XENOBIOTIC METABOLISM; ANIMAL; AREA UNDER THE CURVE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; FECES; HALF LIFE TIME; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; ORAL DRUG ADMINISTRATION; RETINA; TISSUE DISTRIBUTION;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; CARBON RADIOISOTOPES; DOGS; FECES; HALF-LIFE; HERBICIDES; INJECTIONS, INTRAVENOUS; MALE; MICE; PYRIMIDINES; RATS; RETINA; SPECIES SPECIFICITY; TISSUE DISTRIBUTION; TRIAZOLES;

EID: 0030614897     PISSN: 0260437X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1263(199701)17:1<9::AID-JAT390>3.0.CO;2-S     Document Type: Article

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