Dictyostelium transcriptional host cell response upon infection with Legionella

Cellular Microbiology

Volumn 8, Issue 3, 2006, Pages 438-456

  Farbrother, Patrick ^a   Wagner, Carina ^b   Na, Jianbo ^a   Tunggal, Budi ^a   Morio, Takahiro ^c   Urushihara, Hideko ^c   Tanaka, Yoshimasa ^c   Schleicher, Michael ^d   Steinert, Michael ^b   Eichinger, Ludwig ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DICTYOSTELIUM DISCOIDEUM; DNA MICROARRAY; DOWN REGULATION; GENE CONTROL; GENE EXPRESSION; GENE IDENTIFICATION; HOST CELL; HOST PATHOGEN INTERACTION; LEGIONELLA PNEUMOPHILA; LEGIONNAIRE DISEASE; METABOLISM; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; STRESS; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; DICTYOSTELIUM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; LEGIONELLA; LEGIONELLA PNEUMOPHILA; MICROSCOPY, ELECTRON; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTOZOAN PROTEINS; TRANSCRIPTION, GENETIC;

BACTERIA (MICROORGANISMS); DICTYOSTELIUM; DICTYOSTELIUM DISCOIDEUM; LEGIONELLA; LEGIONELLA HACKELIAE; LEGIONELLA PNEUMOPHILA;

EID: 33644829758     PISSN: 14625814     EISSN: 14625822     Source Type: Journal    
DOI: 10.1111/j.1462-5822.2005.00633.x     Document Type: Article

References (60)

1. Alizadeh, A. A., Eisen, M. B., Davis, R. E., Ma, C., Lossos, I. S., Rosenwald, A., et al. (2000) Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403: 503-511.
2. Alli, O. A., Zink, S., Von Lackum, N. K., Abu-Kwaik, Y. (2003) Comparative assessment of virulence traits in Legionella spp. Microbiology 149: 631-641.
3. Anes, E., Kuhnel, M. P., Bos, E., Moniz-Pereira, J., Habermann, A., Griffiths, G. (2003) Selected lipids activate phagosome actin assembly and maturation resulting in killing of pathogenic mycobacteria. Nat Cell Biol 5: 793-802.
4. Blader, I. J., Manger, I. D., Boothroyd, J. C. (2001) Microarray analysis reveals previously unknown changes in Toxoplasma gondii -infected human cells. J Biol Chem 276: 24223-24231.
5. Brazill, D. T., Caprette, D. R., Myler, H. A., Hatton, R. D., Ammann, R. R., Lindsey, D. F., et al. (2000) A protein containing a serine-rich domain with vesicle fusing properties mediates cell cycle-dependent cytosolic pH regulation. J Biol Chem 275: 19231-19240.
6. Cazalet, C., Rusniok, C., Bruggemann, H., Zidane, N., Magnier, A., Ma, L., et al. (2004) Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity. Nat Genet 36: 1165-1173.
7. Chien, M., Morozova, I., Shi, S., Sheng, H., Chen, J., Gomez, S. M., et al. (2004) The genomic sequence of the accidental pathogen Legionella pneumophila. Science 305: 1966-1968.
8. Chisholm, R. L., Firtel, R. A. (2004) Insights into morphogenesis from a simple developmental system. Nat Rev Mol Cell Biol 5: 531-541.
9. Cho, R. J., Huang, M., Campbell, M. J., Dong, H., Steinmetz, L., Sapinoso, L., et al. (2001) Transcriptional regulation and function during the human cell cycle. Nat Genet 27: 48-54.
10. Churchill, G. A. (2002) Fundamentals of experimental design for cDNA microarrays. Nat Genet 32 (Suppl.): 490-495.
11. Cohen, P., Bouaboula, M., Bellis, M., Baron, V., Jbilo, O., Poinot-Chazel, C., et al. (2000) Monitoring cellular responses to Listeria monocytogenes with oligonucleotide arrays. J Biol Chem 275: 11181-11190.
12. Cordevant, C., Tang, J. S., Cleland, D., Lange, M. (2003) Characterization of members of the Legionellaceae family by automated ribotyping. J Clin Microbiol 41: 34-43.
13. Doring, V., Veretout, F., Albrecht, R., Muhlbauer, B., Schlatterer, C., Schleicher, M., Noegel, A. A. (1995) The in vivo role of annexin VII (synexin): Characterization of an annexin VII-deficient Dictyostelium mutant indicates an involvement in Ca (2+) -regulated processes. J Cell Sci 108: 2065-2076.
14. Dowd, C., Wilson, I. W., McFadden, H. (2004) Gene expression profile changes in cotton root and hypocotyl tissues in response to infection with Fusarium oxysporum f. sp. vasinfectum. Mol Plant Microbe Interact 17: 654-667.
15. Dudoit, S., Yang, Y. H. (2003) Bioconductor R packages for exploratory analysis and normalization of cDNA microarray data. In The Analysis of Gene Expression Data: Methods and Software. Parmigiani, G., Garrett, E. S., Irizarray, R. A., Zeger, S. L. (eds). New York: Springer, pp. 42-65.
16. Dudoit, S., Yang, Y. H., Bolstad, B. (2002) Using R for the analysis of DNA microarray data. R News 2: 24-32.
17. Eichinger, L. (2003) Revamp a model-status and prospects of the Dictyostelium genome project. Curr Genet 44: 59-72.
18. Eichinger, L., Pachebat, J. A., Glockner, G., Rajandream, M. A., Sucgang, R., Berriman, M., et al. (2005) The genome of the social amoeba Dictyostelium discoideum. Nature 435: 43-57.
19. Eisen, M. B., Spellman, P. T., Brown, P. O., Botstein, D. (1998) Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 95: 14863-14868.
20. Fajardo, M., Schleicher, M., Noegel, A., Bozzaro, S., Killinger, S., Heuner, K., et al. (2004) Calnexin, calreticulin and cytoskeleton-associated proteins modulate uptake and growth of Legionella pneumophila in Dictyostelium discoideum. Microbiology 150: 2825-2835.
21. Farbrother, P., Müller, S., Noegel, A. A., Eichinger, L. (2002) Comparison of probe preparation methods for DNA microarrays. Biotechniques 33: 884-888.
22. Fraser, D. W., Tsai, T. R., Orenstein, W., Parkin, W. E., Beecham, H. J., Sharrar, R. G., et al. (1977) Legionnaires' disease: Description of an epidemic of pneumonia. N Engl J Med 297: 1189-1197.
23. Gao, L. Y., Abu Kwaik, Y. (1999) Apoptosis in macrophages and alveolar epithelial cells during early stages of infection by Legionella pneumophila and its role in cytopathogenicity. Infect Immun 67: 862-870.
24. Hägele, S., Köhler, R., Merkert, H., Schleicher, M., Hacker, J., Steinert, M. (2000) Dictyostelium discoideum: A new host model system for intracellular pathogens of the genus Legionella. Cell Microbiol 2: 165-171.
25. Harris, M. A., Clark, J., Ireland, A., Lomax, J., Ashburner, M., Foulger, R., et al. (2004) The gene ontology (GO) database and informatics resource. Nucleic Acids Res 32: D258-D261.
26. Horwitz, M. A. (1983) The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion human monocytes. J Exp Med 158: 2108-2126.
27. Horwitz, M. A., Maxfield, F. R. (1984) Legionella pneumophila inhibits acidification of its phagosome in human monocytes. J Cell Biol 99: 1936-1943.
28. Ichikawa, J. K., Norris, A., Bangera, M. G., Geiss, G. K., van't Wout, A. B., Bumgarner, R. E., Lory, S. (2000) Interaction of Pseudomonas aeruginosa with epithelial cells: Identification of differentially regulated genes by expression microarray analysis of human cDNAs. Proc Natl Acad Sci USA 97: 9659-9664.
29. Jones, J. O., Arvin, A. M. (2003) Microarray analysis of host cell gene transcription in response to varicella-zoster virus infection of human T cells and fibroblasts in vitro and SCIDhu skin xenografts in vivo. J Virol 77: 1268-1280.
30. Kwaik, Y. A. (1998) Fatal attraction of mammalian cells to Legionella pneumophila. Mol Microbiol 30: 689-695.
31. Li, Z., Solomon, J. M., Isberg, R. R. (2005) Dictyostelium discoideum strains lacking the RtoA protein are defective for maturation of the Legionella pneumophila replication vacuole. Cell Microbiol 7: 431-442.
32. Lu, H., Clarke, M. (2005) Dynamic properties of Legionella -containing phagosomes in Dictyostelium amoebae. Cell Microbiol 7: 995-1007.
33. Manger, I. D., Relman, D. A. (2000) How the host 'sees' pathogens: global gene expression responses to infection. Curr Opin Immunol 12: 215-218.
34. Noegel, A. A., Schleicher, M. (2000) The actin cytoskeleton of Dictyostelium: A story told by mutants. J Cell Sci 113: 759-766.
35. Noegel, A., Welker, D. L., Metz, B. A., Williams, K. L. (1985) Presence of nuclear associated plasmids in the lower eukaryote Dictyostelium discoideum. J Mol Biol 185: 447-450.
36. Otto, G. P., Wu, M. Y., Clarke, M., Lu, H., Anderson, O. R., Hilbi, H., et al. (2004) Macroautophagy is dispensable for intracellular replication of Legionella pneumophila in Dictyostelium discoideum. Mol Microbiol 51: 63-72.
37. Rosenberger, C. M., Scott, M. G., Gold, M. R., Hancock, R. E., Finlay, B. B. (2000) Salmonella typhimurium infection and lipopolysaccharide stimulation induce similar changes in macrophage gene expression. J Immunol 164: 5894-5904.
38. Roy, C. R., Berger, K. H., Isberg, R. R. (1998) Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake. Mol Microbiol 28: 663-674.
39. Sadosky, A. B., Wiater, L. A., Shuman, H. A. (1993) Identification of Legionella pneumophila genes required for growth within and killing of human macrophages. Infect Immun 61: 5361-5373.
40. Schena, M., Shalon, D., Davis, R. W., Brown, P. O. (1995) Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270: 467-470.
41. Schulze, A., Downward, J. (2001) Navigating gene expression using microarrays - a technology review. Nat Cell Biol 3: E190-E195.
42. Segal, G., Shuman, H. A. (1999) Intracellular multiplication of Legionella pneumophila in human and environmental hosts. In Microbial Ecology and Infectious Disease. Rosenberg, E. (ed.). Washington, DC: American Society for Microbiology Press, pp. 170-186.
43. Smyth, G. K., Yang, Y. H., Speed, T., eds. (2002) Statistical issues in cDNA microarray data analysis.
44. Solomon, J. M., Isberg, R. R. (2000) Growth of Legionella pneumophila in Dictyostelium discoideum: A novel system for genetic analysis of host-pathogen interactions. Trends Microbiol 8: 478-480.
45. Solomon, J. M., Rupper, A., Cardelli, J. A., Isberg, R. R. (2000) Intracellular growth of Legionella pneumophila in Dictyostelium discoideum, a system for genetic analysis of host-pathogen interactions. Infect Immun 68: 2939-2947.
46. Steinert, M., Heuner, K. (2005) Dictyostelium as host model for pathogenesis. Cell Microbiol 7: 307-314.
47. Steinert, M., Leippe, M., Roeder, T. (2003) Surrogate hosts: Protozoa and invertebrates as models for studying pathogen-host interactions. Int J Med Microbiol 293: 321-332.
48. Swanson, M. S., Hammer, B. K. (2000) Legionella pneumophila pathogesesis: A fateful journey from amoebae to macrophages. Annu Rev Microbiol 54: 567-613.
49. Tabor, S. (1990) Expression using the T7 RNA polymerase/promoter system. In Current Protocols in Molecular Biology. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., Struhl, K. (eds). New York: Greene Publishing and Wiley Interscience, pp. 16.2.1-16. 2.11.
50. Tusher, V. G., Tibshirani, R., Chu, G. (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98: 5116-5121.
51. Urushihara, H., Morio, T., Saito, T., Kohara, Y., Koriki, E., Ochiai, H., et al. (2004) Analyses of cDNAs from growth and slug stages of Dictyostelium discoideum. Nucleic Acids Res 32: 1647-1653.
52. Van Haastert, P. J., Devreotes, P. N. (2004) Chemotaxis: Signalling the way forward. Nat Rev Mol Cell Biol 5: 626-634.
53. Vogel, J. P., Andrews, H. L., Wong, S. K., Isberg, R. R. (1998) Conjugative transfer by the virulence system of Legionella pneumophila. Science 279: 873-876.
54. Wiater, L. A., Sadosky, A. B., Shuman, H. A. (1994) Mutagenesis of Legionella pneumophila using Tn903 dlllacZ: Identification of a growth-phase-regulated pigmentation gene. Mol Microbiol 11: 641-653.
55. Wiater, L. A., Dunn, K., Maxfield, F. R., Shuman, H. A. (1998) Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila. Infect Immun 66: 4450-4460.
56. Wintermeyer, E., Ludwig, B., Steinert, M., Schmidt, B., Fischer, G., Hacker, J. (1995) Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells. Infect Immun 63: 4576-4583.
57. van't Wout, A. B., Lehrman, G. K., Mikheeva, S. A., O'Keeffe, G. C., Katze, M. G., Bumgarner, R. E., et al. (2003) Cellular gene expression upon human immunodeficiency virus type 1 infection of CD4 (+) -T-cell lines. J Virol 77: 1392-1402.
58. Xu, Q., Shaulsky, G. (2005) goat: An R tool for analyzing gene ontology term enrichment. Appl Bioinformatics (in press).
59. Yale, J., Bohnert, H. J. (2001) Transcript expression in Saccharomyces cerevisiae at high salinity. J Biol Chem 276: 15996-16007.
60. Yang, Y. H., Speed, T. (2002) Design issues for cDNA microarray experiments. Nat Rev Genet 3: 579-588.