The actin cytoskeleton of Dictyostelium: A story told by mutants

Journal of Cell Science

Volumn 113, Issue 5, 2000, Pages 759-766

  Noegel, Angelika A ^a   Schleicher, Michael ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Actin binding protein; Cell signalling; Chemotaxis; GFP fusion protein; Morphogenesis

Indexed keywords

ACTIN; ACTIN BINDING PROTEIN; CYTOSKELETON PROTEIN; GREEN FLUORESCENT PROTEIN; GUANOSINE TRIPHOSPHATASE; HYBRID PROTEIN;

CELL COMMUNICATION; CHEMOTAXIS; CYTOSKELETON; DICTYOSTELIUM; MORPHOGENESIS; MUTANT; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

DICTYOSTELIUM;

EID: 0034102883     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (12)

1. Adachi, H., Takahashi, Y., Hasebe, T., Shirouzu, M., Yokoyama, S. and Sutoh, K. (1997). Dictyostelium IQGAP-related protein specifically involved in the completion of cytokinesis. J. Cell Biol. 137, 891-898.
2. Aizawa, H., Sutoh, K. and Yahara, I. (1996). Overexpression of cofilin stimulates bundling of actin filaments, membrane ruffling, and cell movement in Dictyostelium. J. Cell Biol. 132, 335-344.
3. Aizawa, H., Fukui, Y. and Yahara, I. (1997). Live dynamics of Dictyostelium cofilin suggests a role in remodeling actin latticework into bundles. J. Cell Sci. 110, 2333-2344.
4. Aizawa, H., Katadae, M., Maruya, M., Sameshima, M., Murakami-Murofushi, K. and Yahara, I. (1999). Hyperosmotic stress-induced reorganization of actin bundles in Dictyostelium cells over-expressing cofilin. Genes Cells 4, 311-324.
5. Alexander, S., Sydow, L. M., Wessels, D. and Soll, D. R. (1992). Discoidin proteins of Dictyostelium are necessary for normal cytoskeletal organization and cellular morphology during aggregation. Differentiation 51, 149-161.
6. Bagrodia, S. and Cerione, R. A. (1999). PAK to the future. Trends Cell Biol. 9, 350-355.
7. Hamburg, J. R., McGough, A. and Ono S. (1999). Putting a new twist on actin: ADF/cofilins modulate actin dynamics. Trends Cell Biol. 9, 364-370.
8. Bear, J. E., Rawls, J. F. and Saxe III, C. L. (1998). Scar, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development. J. Cell Biol. 142, 1325-1335.
9. Buczynski, G., Grove, B., Nomura, A., Kleve, M., Bush, J., Firtel, R. A. and Cardelli, J. (1997). Inativation of two Dictyostelium discoideum genes, DdPIKI and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, and actin cytoskeleton organization. J. Cell Biol. 136, 1271-1286.
10. Chen, P., Ostrow, B. D., Tafuri, S. R. and Chisholm, R. L. (1994). Targeted disruption of the Dictyostelium RMLC gene produces cells defective in cytokinesis and development. J. Cell Biol. 127, 1933-1944.
11. Chung, C. Y. and Firtel, R. A. (1999). PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. J. Cell Biol. 147, 559-576.
12. Zischka, H., Oehme, F., Pintsch, T., Ott, A., Keller, H., Kellermann, J. and Schuster, S. C. (1999). Rearrangement of cortex proteins constitutes an osmoprotective mechanism in Dictyostelium. EMBO J. 18, 4241-4249.