Thermodynamically based profiling of drug metabolism and drug-drug metabolic interactions: A case study of acetaminophen and ethanol toxic interaction

Biophysical Chemistry

Volumn 120, Issue 2, 2006, Pages 121-134

  Yang, Feng ^a   Beard, Daniel A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Acetaminophen hepatotoxicity; Computational model; Drug metabolism; Drug drug interaction; Network thermodynamics

Indexed keywords

ALCOHOL; N ACETYL 1,4 BENZOQUINONE IMINE; PARACETAMOL;

ALCOHOL METABOLISM; ARTICLE; DRUG ALCOHOL INTERACTION; DRUG METABOLISM; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; THERMODYNAMICS;

ACETAMINOPHEN; CELL PHYSIOLOGY; DRUG INTERACTIONS; ENERGY METABOLISM; ETHANOL; MODELS, THEORETICAL; PROTEIN BINDING; THERMODYNAMICS;

EID: 33644784662     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpc.2005.10.013     Document Type: Article

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