Gene silencing of HIV chemokine receptors using ribozymes and single-stranded antisense RNA

Biochemical Journal

Volumn 394, Issue 2, 2006, Pages 511-518

  Qureshi, Amer ^a,b   Zheng, Richard ^b,c   Parlett, Terry ^a   Shi, Xiaoju ^a,b   Balaraman, Priyadhashini ^a,b   Cheloufi, Sihem ^a   Murphy, Brendan ^b   Guntermann, Christine ^b,d   Eagles, Peter ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c UNIVERSITY OF EAST LONDON   (United Kingdom)

^d TeGenero ImmunoTherapeutics AG   (Germany)

Author keywords

Antisense RNA; Chemokine receptor; Gene silencing; Hammerhead ribozyme; HIV; Ribozyme

Indexed keywords

BLOOD; CELL CULTURE; RNA; VIRUSES;

ANTISENSE RNA; CHEMOKINE RECEPTOR; GENE SILENCE; RIBOZYME;

GENES;

ANTIGEN P24; CELL SURFACE RECEPTOR; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; COMPLEMENTARY RNA; HAMMERHEAD RIBOZYME; MESSENGER RNA; RIBOZYME; RNA POLYMERASE;

ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS REPLICATION;

CELLS, CULTURED; DNA-DIRECTED RNA POLYMERASES; FLOW CYTOMETRY; GENE EXPRESSION; GENE SILENCING; HIV-1; HUMANS; LEUKOCYTES, MONONUCLEAR; RECEPTORS, CCR5; RECEPTORS, CXCR4; RNA, ANTISENSE; RNA, CATALYTIC; RNA, MESSENGER; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 33644773580     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20051268     Document Type: Article

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