Ca2+ dysregulation induces mitochondrial depolarization and apoptosis: Role of Na+/Ca2+ exchanger and Akt

Journal of Biological Chemistry

Volumn 280, Issue 46, 2005, Pages 38505-38512

  Miyamoto, Shigeki ^a   Howes, Amy L ^a   Adams, John W ^b   Dorn II, Gerald W ^c   Brown, Joan Heller ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ARENA PHARMACEUTICALS   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CALCIUM; CYTOLOGY; DISEASES; MOLECULAR BIOLOGY; PROTEINS;

APOPTOSIS; MITOCHONDRIAL DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL PERMEABILITY;

CELL MEMBRANES;

CAFFEINE; CALCIUM; DNA FRAGMENT; EGTAZIC ACID; MESSENGER RNA; PROTEIN KINASE B; 1,2 BIS(2 AMINOPHENOXY)ETHANE N,N,N',N' TETRAACETIC ACID ACETOXYMETHYL ESTER; 1,2-BIS(2-AMINOPHENOXY)ETHANE N,N,N',N'-TETRAACETIC ACID ACETOXYMETHYL ESTER; 1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'-TETRAACETIC ACID; DNA; DRUG DERIVATIVE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; SODIUM CALCIUM EXCHANGE PROTEIN;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE PERMEABILITY; CONFOCAL MICROSCOPY; DOWN REGULATION; DRUG ACTIVITY; FLUORESCENCE ACTIVATED CELL SORTING; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NEWBORN; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SARCOPLASMIC RETICULUM; ADENOVIRUS; ANIMAL; CELL CULTURE; CELL MEMBRANE POTENTIAL; CELL SEPARATION; CHEMISTRY; CYTOLOGY; CYTOSOL; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; HEART MUSCLE CELL; METABOLISM; MITOCHONDRION; OSCILLOMETRY; SPECTROFLUOROMETRY; SPRAGUE DAWLEY RAT; TIME;

ADENOVIRIDAE; ANIMALS; APOPTOSIS; CAFFEINE; CALCIUM; CELL SEPARATION; CELLS, CULTURED; CYTOSOL; DNA; DNA FRAGMENTATION; DOWN-REGULATION; EGTAZIC ACID; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; MEMBRANE POTENTIALS; MICROSCOPY, CONFOCAL; MITOCHONDRIA; MYOCYTES, CARDIAC; OSCILLOMETRY; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SARCOPLASMIC RETICULUM; SODIUM-CALCIUM EXCHANGER; SPECTROMETRY, FLUORESCENCE; TIME FACTORS;

EID: 33644686649     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M505223200     Document Type: Article

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