Metalloporphyrin-based superoxide dismutase mimic attenuates the nuclear translocation of apoptosis-inducing factor and the subsequent DNA fragmentation after permanent focal cerebral ischemia in mice

Stroke

Volumn 36, Issue 12, 2005, Pages 2712-2717

  Lee, Byung I ^a   Chan, Pak H ^b   Kim, Gyung W ^a  

^a Yonsei University   (South Korea)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antioxidants; Apoptosis; Cerebral ischemia, focal; Mice

Indexed keywords

APOPTOSIS INDUCING FACTOR; BENZOIC ACID DERIVATIVE; CASPASE 3; CASPASE INHIBITOR; DNA FRAGMENT; MANGANESE TETRAKIS(4 BENZOIC ACID)PORPHYRIN; METALLOPORPHYRIN; PORPHYRIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; CASP3 PROTEIN, MOUSE; CASPASE; MANGANESE(III) TETRAKIS(4 BENZOIC ACID)PORPHYRIN; MANGANESE(III)-TETRAKIS(4-BENZOIC ACID)PORPHYRIN; PDCD8 PROTEIN, MOUSE;

ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN VENTRICLE; ENZYME ACTIVITY; ENZYME INHIBITION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PULSED FIELD GEL ELECTROPHORESIS; WESTERN BLOTTING; ANIMAL; CELL DEATH; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; GENE TRANSLOCATION; GENETICS; IN VITRO STUDY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM;

ANIMALS; APOPTOSIS INDUCING FACTOR; BLOTTING, WESTERN; BRAIN ISCHEMIA; CASPASE 3; CASPASES; CELL DEATH; DNA FRAGMENTATION; FLUORESCENT ANTIBODY TECHNIQUE; MALE; METALLOPORPHYRINS; MICE; MICE, INBRED ICR; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TRANSLOCATION, GENETIC;

EID: 33644663413     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.0000190001.97140.cf     Document Type: Article

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