Nonsteroidal anti-inflammatory drugs potentiate 1-methyl-4-phenylpyridinium (MPP+)-induced cell death by promoting the intracellular accumulation of MPP+ in PC12 cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 2, 2004, Pages 800-807

  Morioka, Norimitsu ^a   Kumagai, Kei ^a   Morita, Katsuya ^a   Kitayama, Shigeo ^b   Dohi, Toshihiro ^a,c  

^a HIROSHIMA UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c NONE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 2 CHLORO 5 NITROBENZANILIDE; ACETYLASPARTYLGLUTAMYLVALYLASPARTALDEHYDE; ACETYLCYSTEINE; ACETYLSALICYLIC ACID; ANTIOXIDANT; BENZAMIDE DERIVATIVE; CASPASE 3 INHIBITOR; DICLOFENAC; DNA FRAGMENT; IBUPROFEN; INDOMETACIN; KETOPROFEN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N TERT BUTYL ALPHA PHENYLNITRONE; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTICATED RECEPTOR GAMMA ANTAGONIST; RECEPTOR BLOCKING AGENT; SCAVENGER; UNCLASSIFIED DRUG; VERLUKAST;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL TRANSPORT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; NONHUMAN; PRIORITY JOURNAL; RAT;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL DEATH; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; INTRACELLULAR FLUID; PC12 CELLS; RATS;

EID: 3342950145     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.065300     Document Type: Article

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