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Volumn 36, Issue 6, 2000, Pages 489-497

Effect of 1-methyl-4-phenylpyridinium on glutathione in rat pheochromocytoma PC 12 cells

Author keywords

1 methyl 4 phenylpyridinium; Glutathione; Rat pheochromocytoma PC 12 cells; Reactive oxygen intermediates

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; GLUTATHIONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); ROTENONE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 0033976655     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-0186(99)00156-4     Document Type: Article
Times cited : (41)

References (45)
  • 1
    • 0025043947 scopus 로고
    • Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples
    • Baker M.A., Cerniglia G.J., Zaman A. Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples. Anal. Biochem. 190:1990;360-365.
    • (1990) Anal. Biochem. , vol.190 , pp. 360-365
    • Baker, M.A.1    Cerniglia, G.J.2    Zaman, A.3
  • 2
    • 0028834192 scopus 로고
    • L-dopa cytotoxicity to PC12 cells in culture is via its autoxidation
    • Basma A.N., Morris E.J., Nicklas W.J., Geller H.M. L-dopa cytotoxicity to PC12 cells in culture is via its autoxidation. J. Neurochem. 64:1995;825-832.
    • (1995) J. Neurochem. , vol.64 , pp. 825-832
    • Basma, A.N.1    Morris, E.J.2    Nicklas, W.J.3    Geller, H.M.4
  • 3
    • 0028064964 scopus 로고
    • Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: Evidence for a primary involvement of energy depletion
    • Bates T.E., Heales S.J., Davies S.E., Boakye P., Clark J.B. Effects of 1-methyl-4-phenylpyridinium on isolated rat brain mitochondria: evidence for a primary involvement of energy depletion. J. Neurochem. 63:1994;640-648.
    • (1994) J. Neurochem. , vol.63 , pp. 640-648
    • Bates, T.E.1    Heales, S.J.2    Davies, S.E.3    Boakye, P.4    Clark, J.B.5
  • 4
    • 0029125857 scopus 로고
    • Aging, energy, and oxidative stress in neurodegenerative diseases
    • Beal M.F. Aging, energy, and oxidative stress in neurodegenerative diseases. Ann. Neurol. 38:1995;3566-3573.
    • (1995) Ann. Neurol. , vol.38 , pp. 3566-3573
    • Beal, M.F.1
  • 5
    • 0030057990 scopus 로고    scopus 로고
    • Age-dependent sensitivity of cultured peripheral sympathetic neurons to 1-methyl-4-phenylpyridinium: Role of glutathione
    • Bhave S.V., Johannessen J.N., Lash L.H., Wakade T.D., Wakade A.R. Age-dependent sensitivity of cultured peripheral sympathetic neurons to 1-methyl-4-phenylpyridinium: role of glutathione. J. Neurochem. 67:1996;557-565.
    • (1996) J. Neurochem. , vol.67 , pp. 557-565
    • Bhave, S.V.1    Johannessen, J.N.2    Lash, L.H.3    Wakade, T.D.4    Wakade, A.R.5
  • 6
    • 0031455734 scopus 로고    scopus 로고
    • Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease
    • Cassarino D.S., Fall C.P., Swerdlow R.H., Smith T.S., Halvorsen E.M., Miller S.W., et al. Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease. Biochim. Biophys. Acta. 1362:1997;77-86.
    • (1997) Biochim. Biophys. Acta , vol.1362 , pp. 77-86
    • Cassarino, D.S.1    Fall, C.P.2    Swerdlow, R.H.3    Smith, T.S.4    Halvorsen, E.M.5    Miller, S.W.6
  • 7
    • 0032951125 scopus 로고    scopus 로고
    • The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism
    • Cassarino D.S., Parks J.K., Parker W.D. Jr, Bennett J.P. Jr. The parkinsonian neurotoxin MPP+ opens the mitochondrial permeability transition pore and releases cytochrome c in isolated mitochondria via an oxidative mechanism. Biochim. Biophys. Acta. 1453:1999;49-62.
    • (1999) Biochim. Biophys. Acta , vol.1453 , pp. 49-62
    • Cassarino, D.S.1    Parks, J.K.2    Parker W.D., Jr.3    Bennett J.P., Jr.4
  • 8
    • 0026598930 scopus 로고
    • Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: Evidence for free radical involvement
    • Cleeter M.W., Cooper J.M., Schapira A.H. Irreversible inhibition of mitochondrial complex I by 1-methyl-4-phenylpyridinium: evidence for free radical involvement. J. Neurochem. 58:1992;786-789.
    • (1992) J. Neurochem. , vol.58 , pp. 786-789
    • Cleeter, M.W.1    Cooper, J.M.2    Schapira, A.H.3
  • 10
    • 0023185105 scopus 로고
    • A dopaminergic cell line variant resistant to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Denton T., Howard B.D. A dopaminergic cell line variant resistant to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J. Neurochem. 49:1987;622-630.
    • (1987) J. Neurochem. , vol.49 , pp. 622-630
    • Denton, T.1    Howard, B.D.2
  • 11
    • 0029003506 scopus 로고
    • Neuronal antioxidant system and MPTP-induced oxidative stress in the striatum and brain stem of the rat
    • Desole M.S., Miele M., Esposito G., Fresu L.G., Migheli R., Zangani D., et al. Neuronal antioxidant system and MPTP-induced oxidative stress in the striatum and brain stem of the rat. Pharmacol. Biochem. Behav. 51:1995;581-592.
    • (1995) Pharmacol. Biochem. Behav. , vol.51 , pp. 581-592
    • Desole, M.S.1    Miele, M.2    Esposito, G.3    Fresu, L.G.4    Migheli, R.5    Zangani, D.6
  • 12
    • 0023653496 scopus 로고
    • Increased efflux rather than oxidation is the mechanism of glutathione depletion by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
    • Di Monte D., Sandy M.S., Smith M.T. Increased efflux rather than oxidation is the mechanism of glutathione depletion by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Biochem. Biophys. Res. Commun. 148:1987;153-160.
    • (1987) Biochem. Biophys. Res. Commun. , vol.148 , pp. 153-160
    • Di Monte, D.1    Sandy, M.S.2    Smith, M.T.3
  • 13
    • 0026694525 scopus 로고
    • Glutathione in Parkinson's disease: A link between oxidative stress and mitochondrial damage?
    • Di Monte D.A., Chan P., Sandy M.S. Glutathione in Parkinson's disease: a link between oxidative stress and mitochondrial damage? Ann. Neurol. 32:1992;S111-S115.
    • (1992) Ann. Neurol. , vol.32
    • Di Monte, D.A.1    Chan, P.2    Sandy, M.S.3
  • 14
    • 0030984429 scopus 로고    scopus 로고
    • Involvement of a caspase-3-like cysteine protease in 1-methyl-4-phenylpyridinium-mediated apoptosis of cultured cerebellar granule neurons
    • Du Y., Dodel R.C., Bales K.R., Jemmerson R., Hamilton Byrd E., Paul S.M. Involvement of a caspase-3-like cysteine protease in 1-methyl-4-phenylpyridinium-mediated apoptosis of cultured cerebellar granule neurons. J. Neurochem. 69:1997;1382-1388.
    • (1997) J. Neurochem. , vol.69 , pp. 1382-1388
    • Du, Y.1    Dodel, R.C.2    Bales, K.R.3    Jemmerson, R.4    Hamilton Byrd, E.5    Paul, S.M.6
  • 15
    • 0033569747 scopus 로고    scopus 로고
    • Bcl-2 and Mitochondrial Oxygen Radicals. New approaches with reactive oxygen species-sensitive probes
    • Esposti M.D., Hatzinisiriou I., McLennan H., Ralph S. Bcl-2 and Mitochondrial Oxygen Radicals. New approaches with reactive oxygen species-sensitive probes. J. Biol. Chem. 274:1999;29,831-29,837.
    • (1999) J. Biol. Chem. , vol.274 , pp. 29
    • Esposti, M.D.1    Hatzinisiriou, I.2    McLennan, H.3    Ralph, S.4
  • 16
    • 0027484368 scopus 로고
    • Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductase
    • Estornell E., Fato R., Pallotti F., Lenaz G. Assay conditions for the mitochondrial NADH:coenzyme Q oxidoreductase. FEBS Lett. 332:1993;127-131.
    • (1993) FEBS Lett. , vol.332 , pp. 127-131
    • Estornell, E.1    Fato, R.2    Pallotti, F.3    Lenaz, G.4
  • 17
    • 0029656203 scopus 로고    scopus 로고
    • Acute MPTP treatment produces no changes in mitochondrial complex activities and indices of oxidative damage in the common marmoset ex vivo one week after exposure to the toxin
    • Gerlach M., Gotz M., Dirr A., Kupsch A., Janetzky B., Oertel W., et al. Acute MPTP treatment produces no changes in mitochondrial complex activities and indices of oxidative damage in the common marmoset ex vivo one week after exposure to the toxin. Neurochem. Int. 28:1996;41-49.
    • (1996) Neurochem. Int. , vol.28 , pp. 41-49
    • Gerlach, M.1    Gotz, M.2    Dirr, A.3    Kupsch, A.4    Janetzky, B.5    Oertel, W.6
  • 18
    • 0026718965 scopus 로고
    • Quantitative autoradiography of dihydrorotenone binding to complex I of the electron transport chain
    • Greenamyre J.T., Higgins D.S., Eller R.V. Quantitative autoradiography of dihydrorotenone binding to complex I of the electron transport chain. J. Neurochem. 59:1992;746-749.
    • (1992) J. Neurochem. , vol.59 , pp. 746-749
    • Greenamyre, J.T.1    Higgins, D.S.2    Eller, R.V.3
  • 19
    • 0018800337 scopus 로고
    • Inhibition of glutathione biosynthesis by prothionine sulfoximine (S-n-propyl homocysteine sulfoximine), a selective inhibitor of gamma-glutamylcysteine synthetase
    • Griffith O.W., Anderson M.E., Meister A. Inhibition of glutathione biosynthesis by prothionine sulfoximine (S-n-propyl homocysteine sulfoximine), a selective inhibitor of gamma-glutamylcysteine synthetase. J. Biol. Chem. 254:1979;1205-1220.
    • (1979) J. Biol. Chem. , vol.254 , pp. 1205-1220
    • Griffith, O.W.1    Anderson, M.E.2    Meister, A.3
  • 20
    • 0030969014 scopus 로고    scopus 로고
    • Interaction of the mitochondrial NADH-ubiquinone reductase with rotenone as related to the enzyme active/inactive transition
    • Grivennikova V.G., Maklashina E.O., Gavrikova E.V., Vinogradov A.D. Interaction of the mitochondrial NADH-ubiquinone reductase with rotenone as related to the enzyme active/inactive transition. Biochim. Biophys. Acta. 1319:1997;223-232.
    • (1997) Biochim. Biophys. Acta , vol.1319 , pp. 223-232
    • Grivennikova, V.G.1    Maklashina, E.O.2    Gavrikova, E.V.3    Vinogradov, A.D.4
  • 21
    • 0030059868 scopus 로고    scopus 로고
    • L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress
    • Han S.K., Mytilineou C., Cohen G. L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress. J. Neurochem. 66:1996;501-510.
    • (1996) J. Neurochem. , vol.66 , pp. 501-510
    • Han, S.K.1    Mytilineou, C.2    Cohen, G.3
  • 22
    • 84975751684 scopus 로고
    • Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: Relevance to Parkinson's disease
    • Hartley A., Stone J.M., Heron C., Cooper J.M., Schapira A.H. Complex I inhibitors induce dose-dependent apoptosis in PC12 cells: relevance to Parkinson's disease. J. Neurochem. 63:1994;1987-1990.
    • (1994) J. Neurochem. , vol.63 , pp. 1987-1990
    • Hartley, A.1    Stone, J.M.2    Heron, C.3    Cooper, J.M.4    Schapira, A.H.5
  • 23
    • 0029553558 scopus 로고
    • 1-Methyl-4-phenylpyridinium (MPP+) inhibits mitochondrial oxygen consumption mediated by succinate as well as malate in rat pheochromocytoma PC12 cells
    • Hasegawa E., Asagami H., Kang D., Minakami S., Takeshige K. 1-Methyl-4-phenylpyridinium (MPP+) inhibits mitochondrial oxygen consumption mediated by succinate as well as malate in rat pheochromocytoma PC12 cells. Biochem. Mol. Biol. Int. 35:1995;409-413.
    • (1995) Biochem. Mol. Biol. Int. , vol.35 , pp. 409-413
    • Hasegawa, E.1    Asagami, H.2    Kang, D.3    Minakami, S.4    Takeshige, K.5
  • 25
    • 0024997609 scopus 로고
    • 1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles
    • Hasegawa E., Takeshige K., Oishi T., Minakami S. 1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles. Biochem. Biophys. Res. Commun. 170:1990;1049-1055.
    • (1990) Biochem. Biophys. Res. Commun. , vol.170 , pp. 1049-1055
    • Hasegawa, E.1    Takeshige, K.2    Oishi, T.3    Minakami, S.4
  • 26
    • 0342872019 scopus 로고    scopus 로고
    • Elevated expression of glutathione peroxidase in PC12 cells results in protection against methamphetamine but not MPTP toxicity
    • Hom D.J., Jiang D., Hong E.J., Mo J.Q., Andersen J.K. Elevated expression of glutathione peroxidase in PC12 cells results in protection against methamphetamine but not MPTP toxicity. Brain Res. Mol. Brain Res. 46:1997;154-160.
    • (1997) Brain Res. Mol. Brain Res. , vol.46 , pp. 154-160
    • Hom, D.J.1    Jiang, D.2    Hong, E.J.3    Mo, J.Q.4    Andersen, J.K.5
  • 28
    • 0026554428 scopus 로고
    • Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress
    • LeBel C.P., Ischiropoulos H., Bondy S.C. Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem. Res. Toxicol. 5:1992;227-231.
    • (1992) Chem. Res. Toxicol. , vol.5 , pp. 227-231
    • Lebel, C.P.1    Ischiropoulos, H.2    Bondy, S.C.3
  • 32
    • 0030016523 scopus 로고    scopus 로고
    • Oxidative damage caused by free radicals produced during catecholamine autoxidation: Protective effects of O-methylation and melatonin
    • Miller J.W., Selhub J., Joseph J.A. Oxidative damage caused by free radicals produced during catecholamine autoxidation: protective effects of O-methylation and melatonin. Free Radic. Biol. Med. 21:1996;241-249.
    • (1996) Free Radic. Biol. Med. , vol.21 , pp. 241-249
    • Miller, J.W.1    Selhub, J.2    Joseph, J.A.3
  • 33
    • 0026720018 scopus 로고
    • Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes
    • Mithofer K., Sandy M.S., Smith M.T., Di Monte D. Mitochondrial poisons cause depletion of reduced glutathione in isolated hepatocytes. Arch. Biochem. Biophys. 295:1992;132-136.
    • (1992) Arch. Biochem. Biophys. , vol.295 , pp. 132-136
    • Mithofer, K.1    Sandy, M.S.2    Smith, M.T.3    Di Monte, D.4
  • 34
    • 0023111239 scopus 로고
    • Inhibition of mitochondrial alpha-ketoglutarate dehydrogenase by 1-methyl-4-phenylpyridinium ion
    • Mizuno Y., Saitoh T., Sone N. Inhibition of mitochondrial alpha-ketoglutarate dehydrogenase by 1-methyl-4-phenylpyridinium ion. Biochem. Biophys. Res. Commun. 143:1987;971-976.
    • (1987) Biochem. Biophys. Res. Commun. , vol.143 , pp. 971-976
    • Mizuno, Y.1    Saitoh, T.2    Sone, N.3
  • 35
    • 0030604251 scopus 로고    scopus 로고
    • Protective effect of carbidopa on hydroxyl radical generation in the rat striatum by dopamine
    • Obata T., Yamanaka Y. Protective effect of carbidopa on hydroxyl radical generation in the rat striatum by dopamine. Neurosci. Lett. 221:1996;13-16.
    • (1996) Neurosci. Lett. , vol.221 , pp. 13-16
    • Obata, T.1    Yamanaka, Y.2
  • 36
    • 0026100563 scopus 로고
    • Interaction of 1-methyl-4-phenylpyridinium ion (MPP+) and its analogs with the rotenone/piericidin binding site of NADH dehydrogenase
    • Ramsay R.R., Krueger M.J., Youngster S.K., Gluck M.R., Casida J.E., Singer T.P. Interaction of 1-methyl-4-phenylpyridinium ion (MPP+) and its analogs with the rotenone/piericidin binding site of NADH dehydrogenase. J. Neurochem. 56:1991;1184-1190.
    • (1991) J. Neurochem. , vol.56 , pp. 1184-1190
    • Ramsay, R.R.1    Krueger, M.J.2    Youngster, S.K.3    Gluck, M.R.4    Casida, J.E.5    Singer, T.P.6
  • 38
    • 0033515794 scopus 로고    scopus 로고
    • Differential effects of L-buthionine sulfoximine and ethacrynic acid on glutathione levels and mitochondrial function in PC12 cells
    • Seyfried J., Soldner F., Schulz J.B., Klockgether T., Kovar K.A., Wullner U. Differential effects of L-buthionine sulfoximine and ethacrynic acid on glutathione levels and mitochondrial function in PC12 cells. Neurosci. Lett. 264:1999;1-4.
    • (1999) Neurosci. Lett. , vol.264 , pp. 1-4
    • Seyfried, J.1    Soldner, F.2    Schulz, J.B.3    Klockgether, T.4    Kovar, K.A.5    Wullner, U.6
  • 39
    • 0028075410 scopus 로고
    • Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia
    • Sian J., Dexter D.T., Lees A.J., Daniel S., Agid Y., Agid F. Javoy, et al. Alterations in glutathione levels in Parkinson's disease and other neurodegenerative disorders affecting basal ganglia. Ann. Neurol. 36:1994;348-355.
    • (1994) Ann. Neurol. , vol.36 , pp. 348-355
    • Sian, J.1    Dexter, D.T.2    Lees, A.J.3    Daniel, S.4    Agid, Y.5    Agid, F.J.6
  • 40
    • 0028350560 scopus 로고
    • L-dopa increases nigral production of hydroxyl radicals in vivo: Potential L-dopa toxicity?
    • Smith T.S., Parker W.D. Jr, Bennett J.P. Jr. L-dopa increases nigral production of hydroxyl radicals in vivo: potential L-dopa toxicity? Neuroreport. 5:1994;1009-1011.
    • (1994) Neuroreport , vol.5 , pp. 1009-1011
    • Smith, T.S.1    Parker W.D., Jr.2    Bennett J.P., Jr.3
  • 41
    • 0033542739 scopus 로고    scopus 로고
    • MPP+ inhibits proliferation of PC12 cells by a p21(WAF1/Cip1)-dependent pathway and induces cell death in cells lacking p21(WAF1/Cip1)
    • Soldner F., Weller M., Haid S., Beinroth S., Miller S.W., U Wl, et al. MPP+ inhibits proliferation of PC12 cells by a p21(WAF1/Cip1)-dependent pathway and induces cell death in cells lacking p21(WAF1/Cip1). Exp. Cell. Res. 250:1999;75-85.
    • (1999) Exp. Cell. Res. , vol.250 , pp. 75-85
    • Soldner, F.1    Weller, M.2    Haid, S.3    Beinroth, S.4    Miller, S.W.5    U., W.6
  • 42
    • 0030888286 scopus 로고    scopus 로고
    • In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining
    • Tatton N.A., Kish S.J. In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining. Neuroscience. 77:1997;1037-1048.
    • (1997) Neuroscience , vol.77 , pp. 1037-1048
    • Tatton, N.A.1    Kish, S.J.2
  • 43
    • 0014481378 scopus 로고
    • Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues
    • Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal. Biochem. 27:1969;502-522.
    • (1969) Anal. Biochem. , vol.27 , pp. 502-522
    • Tietze, F.1
  • 45
    • 0029949789 scopus 로고    scopus 로고
    • Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones
    • Wüllner U., Löschmann P.A., Schulz J.B., Schmid A., Dringen R., Eblen F., et al. Glutathione depletion potentiates MPTP and MPP+ toxicity in nigral dopaminergic neurones. Neuroreport. 7:1996;921-923.
    • (1996) Neuroreport , vol.7 , pp. 921-923
    • Wüllner, U.1    Löschmann, P.A.2    Schulz, J.B.3    Schmid, A.4    Dringen, R.5    Eblen, F.6


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