A convenient synthesis of N1-substituted 3,4-dihydropyrimidin-2(1H)-ones by cyclocondensation of α-chlorobenzyl isocyanates with ethyl N-alkyl(aryl)-β-aminocrotonates

Synlett

Volumn , Issue 3, 2006, Pages 375-378

  Sukach, Volodymyr A ^a   Bol'but, Andriy V ^a   Sinitsa, Anatoliy D ^a   Vovk, Mykhaylo V ^a  

^a INSTITUTE OF HYDROBIOLOGY   (Ukraine)

Author keywords

chloroalkyl isocyanates; aminocrotonic esters; Cyclocondensation; Dihydropyrimidones; Regioselectivity

Indexed keywords

ALKYL GROUP; CROTONIC ACID DERIVATIVE; ISOCYANIC ACID DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PYRIMIDINE DERIVATIVE;

ARTICLE; BIGINELLI REACTION; CHEMICAL STRUCTURE; POLYMERIZATION; SUBSTITUTION REACTION; SYNTHESIS;

EID: 33344466917     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-926241     Document Type: Article

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42. 2SO]: δ = 14.47, 16.50, 45.43, 52.44, 60.22, 103.65, 126.62, 127.35, 128.62, 128.85, 128.95, 132.47, 139.06, 143.38, 150.30, 153.34, 165.91.
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45. 2SO]: δ = 14.45, 30.46, 52.62, 61.05, 102.91, 122.35, 125.51, 126.14, 126.73, 127.92, 129.17, 129.63, 130.68, 131.11, 131.60, 135.04, 145.78, 150.24, 151.86, 165.17.