L-Carnitine suppresses the onset of neuromuscular degeneration and increases the life span of mice with familial amyotrophic lateral sclerosis

Brain Research

Volumn 1070, Issue 1, 2006, Pages 206-214

  Kira, Yukimi ^a   Nishikawa, Manabu ^a   Ochi, Akemi ^a   Sato, Eisuke ^a   Inoue, Masayasu ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Amyotrophic lateral sclerosis; Apoptosis; Carnitine; Mitochondrion; Neuron; Oxidative stress; SOD1

Indexed keywords

CARNITINE; COPPER ZINC SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG TISSUE LEVEL; FAMILIAL DISEASE; FATTY ACID OXIDATION; FEMALE; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; LIFESPAN; MALE; MITOCHONDRION; MOTOR ACTIVITY; MOUSE; MUTAGENESIS; NEUROMUSCULAR DISEASE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE; TRANSGENIC MOUSE;

ADENINE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; APOPTOSIS; CARNITINE; DISEASE PROGRESSION; FEMALE; GUANINE; HINDLIMB; HUMANS; INJECTIONS, SUBCUTANEOUS; LONGEVITY; MALE; MICE; MICE, TRANSGENIC; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUTATION; NERVE DEGENERATION; NERVE TISSUE PROTEINS; OXIDATION-REDUCTION; SPINAL CORD; SUPEROXIDE DISMUTASE; VITAMIN B COMPLEX;

ANIMALIA; MUS MUSCULUS;

EID: 32644466209     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.11.052     Document Type: Article

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