Characteristics of cardiac hypertrophy in the juvenile visceral steatosis mouse with systemic carnitine deficiency

Journal of Molecular and Cellular Cardiology

Volumn 30, Issue 4, 1998, Pages 773-781

  Kuwajima, Masamichi ^a   Lu, Kang Mo ^a   Sei, Masako ^a   Ono, Akira ^b   Hayashi, Miyuki ^a   Ishiguro, Kirie ^a   Ozaki, Kiyokazu ^c   Hotta, Kikuko ^b   Okita, Kohei ^b   Murakami, Takashi ^a   Miyagawa, Jun Ichiro ^b   Narama, Isao ^c   Nikaido, Hiroko ^d   Hayakawa, Jun Ichiro ^d   Nakajima, Hiromu ^b   Namba, Mitsuyoshi ^b   Hanafusa, Toshiaki ^b   Matsuzawa, Yuji ^b   Shima, Kenji ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c SETSUNAN UNIVERSITY   (Japan)

^d KANAZAWA UNIVERSITY   (Japan)

Author keywords

Cardiomyopathy; Carnitine; Lipid droplet; Mitochondria; Mouse

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; CARNITINE; LIPID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CARNITINE DEFICIENCY; CELL GROWTH; CONTROLLED STUDY; ELECTRON MICROSCOPY; ENERGY; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE SEPTUM; HEART VENTRICLE WALL; HEART WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEATOSIS; VISCERA;

ANIMALIA;

EID: 0032054618     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0641     Document Type: Article

References (40)

1. BELTRAMI CA, FINATO N, ROCCO M, FERUGLIO GA, PURICELLI C, CIGOLA E, QUAINI F, SONNENBLICK EH, OLIVETTI G, ANVERSA P, 1994. Structural basis of end-stage failure in ischemic cardiomyopathy in humans. Circulation 89: 151-163.
2. BÖHMER T, EIKLID K, JONSEN J, 1977. Carnitine uptake into human heart cells in culture. Biochim Biophys Acta 465: 627-633.
3. BREMER J, 1983. Carnitine - metabolism and functions. Physiol Rev 63: 1420-1480.
4. BRODERICK TL, QUINNEY HA, BARKER CC, LOPASCHUK GD, 1993. Beneficial effect of carnitine on mechanical recovery of rat hearts reperfused after a transient period of global ischemia is accompanied by a stimulation of glucose oxidation. Circulation 87: 972-981.
5. BROWNELL AKW, ENGEL AG, 1978. Experimental lipid storage myopathy. J Neurol Sci 35: 31-41.
6. FOSTER KA, O'ROURKE B, REIBEL DK, 1985. Altered carnitine metabolism in spontaneously hypertensive rats. Am J Physiol 249: E183-E186.
7. o mice. Mouse Genome 86: 261.
8. HORIUCHI M, YOSHIDA H, KOBAYASHI K, KURIWAKI K, YOSHIMINE K, TOMOMURA M, KOIZUMI T, NIKAIDO H, HAYAKAWA J, KUWAJIMA M, SAHEKI T, 1993. Cardiac hypertrophy in juvenile visceral steatosis (jvs) mice with systemic carnitine deficiency. FEBS Lett 326: 267-271.
9. HORIUCHI M, KOBAYASHI K, YAMAGUCHI S, SHIMIZU N, KOIZUMI T, NIKAIDO H, HAYAKAWA J, KUWAJIMA M, SAHEKI T, 1994. Primary defect of juvenile visceral steatosis (jvs) mouse with systemic carnitine deficiency is probably in renal carnitine transport system. Biochim Biophys Acta 1226: 25-30.
10. KELLY DP, STRAUSS AW, 1994. Inherited cardiomyopathies. N Engl J Med 330: 913-919.
11. KOBAYASHI A, MASUMURA Y, YAMAZAKI N, 1992. L-carnitine treatment for congestive heart failure -experimental and clinical study. Jpn Circ J 56: 86-94.
12. o strain of mouse with similarities to Reye's syndrome. Laboratory Animals 22: 83-87.
13. KURIBAYASHI T, 1987. Spontaneously occurring hypertrophic cardiomyopathy in the rat. I. Pathologic features. Jpn Circ J 51: 573-588.
14. o strain of mouse associated with juvenile visceral steatosis. Biochem Biophys Res Commun 174: 1090-1094.
15. KUWAJIMA M, LU K-M, HARASHIMA H, ONO A, SATO I, MIZUNO A, MURAKAMI T, NAKAJIMA H, MIYAGAWA J, NAMBA M, HANAFUSA T, HAYAKAWA J, MATSUZAWA Y, SHIMA K, 1996. Carnitine transport defect in flbroblasts of juvenile visceral steatosis (JVS) mouse. Biochem Biophys Res Commun 223: 283-287.
16. LISSONI P, GALLI MA, TANCINI G, BARNI S, 1993. Prevention by L-carnitine of interleukin-2-related cardiac toxicity during cancer immunotherapy. Tumori 79: 202-204.
17. LOPASCHUK GD, BELKE DD, GAMBLE J, ITOI T, SCHÖNEKESS BO, 1994. Regulation of fatty acid oxidation in the mammalian heart in health and disease. Biochim Biophys Acta 1213: 263-276.
18. MATSUISHI T, HIRATA K, TERASAWA K, KATO H, YOSHINO M, OHTAKI E, HIROSE F, 1985. Successful carnitine treatment in two siblings having lipid storage myopathy with hypertrophic cardiomyopathy. Neuropediatrics 16: 6-12.
19. MATSUMORI A, KAWAI C, 1982. An animal model of congestive (dilated) cardiomyopathy: dilatation and hypertrophy of the heart in the chronic stage in DBA/2 mice with myocarditis caused by encephalomyocarditis virus. Circulation 66: 355-360.
20. MCGARRY JD, FOSTER DW, 1976. An improved and simplified radioisotopic assay for the determination of free and esterifled carnitine. J Lipid Res 17: 277-281.
21. MCGARRY JD, WOELTJE KF, KUWAJIMA M, FOSTER DW, 1989. Regulation of ketogenesis and the renaissance of carnitine palmitoyltransferase. Diabetes/Metab Rev 5: 271-284.
22. MCHOWAT J, YAMADA KA, WU J, YAN G-X, CORR PB, 1993. Recent insights pertaining to sarcolemmal phospholipid alterations underlying arrhythmogenesis in the ischemic heart. J Cardiovasc Electrophysiol 4: 288-310.
23. MICHELETTI R, DI PAOLA ED, SCHIAVONE A, ENGLISH E, BENATTI P, CAPASSO JM, ANVERSA P, BIANCHI G, 1993. Propionyl-L-carnitine limits chronic ventricular dilation after myocardial infarction in rats. Am J Physiol 264: H1111-H1117.
24. MIYAGAWA J, KUWAJIMA M, HANAFUSA T, OZAKI K, FUJIMURA H, ONO A, UENAKA R, NARAMA I, OUE T, YAMAMOTO K, KAIDOH M, NIKAIDO H, HAYAKAWA J, HORIUCHI M, SAHEKI T, MATSUZAWA Y, 1995. Mitochondrial abnormalities of muscle tissue in mice with juvenile visceral steatosis associated with systemic carnitine deficiency. Virchows Archiv 426: 271-279.
25. NEELY JR, MORGAN HE, 1974. Relationship between carbohydrate and lipid metabolism and the energy balance of heart muscle. Ann Rev Physiol 36: 413-459.
26. NEELY JR, ROVETTO MJ, ORAM JF, 1972. Myocardial utilization of carbohydrate and lipids. Prog Cardiovasc Diseases 15: 289-329.
27. OPIE LH, 1968. Metabolism of the heart in health and disease. Part I. Am Heart J 76: 685-698.
28. OPIE LH, 1979. Role of carnitine in fatty acid metabolism of normal and ischemic myocardium. Am Heart J 97: 375-388.
29. PANDE SV, BLANCHAER MC, 1971. Reversible inhibition of mitochondrial adenosine diphosphate phosphorylation by long chain acyl coenzyme A esters. J Biol Chem 246: 402-411.
30. PYERITZ RE, 1997. Carnitine deficiency. In: Braunwald E (ed.). Heart Disease. 5th ed. Philadelphia: W.B. Saunders, 1674.
31. REGITZ V, MÜLLER M, SCHÜLER S, YANKAH CA, HETZER R, SHUG AL, FLECK E, 1987. Carnitinstoffwechsel -Veränderungen im Endstadium der dilatativen Kardiomyopathie und der ischämischen Herzmuskelerkrankung. Z Kardiol 76 (Suppl. 5): 1-8.
32. REIBEL DK, UBOH CE, KENT RL, 1983. Altered coenzyme A and carnitine metabolism in pressure-overload hypertrophied hearts. Am J Physiol 244: H839-H843.
33. RODRIGUES B, ROSS JR, FARAHBAKSHIAN S, MCNEILL JH, 1990. Effects of in vivo and in vitro treatment with L-carnitine on isolated hearts from chronically diabetic rats. Can J Physiol Pharmacol 68: 1085-1092.
34. SCHOLTE HR, PEREIRA RR, DE JONGE PC, LUYT-HOUWEN IEM, VERDUIN MHM, ROSS JD, 1990. Primary carnitine deficiency. J Clin Chem Clin Biochem 28: 351-357.
35. TEIN I, DE VIVO DC, BIERMAN F, PULVER P, DE MEIRLEIR LJ, CVITANOVIC-SOJAT L, PAGON RA, BERTINI E, DIONISIVICI C, SERVIDEI S, DIMAURO S, 1990. Impaired skin fibroblast carnitine uptake in primary systemic carnitine deficiency manifested by childhood carnitine-responsive cardiomyopathy. Pediatr Res 28: 247-255.
36. TOWBIN J, ROBERTS R, 1994. Carnitine deficiency. In: Schlant RC and Alexander RW (eds). The Heart. 8th ed. New York: McGraw-Hill, 1741.
37. TREEM WR, STANLEY CA, FINEGOLD DN, HALE DE, COATES PM, 1988. Primary carnitine deficiency due to a failure of carnitine transport in kidney, muscle, and fibroblasts. N Engl J Med 319: 1331-1336.
38. TRIPP ME, KATCHER ML, PETERS HA, GILBERT EF, ARYA S, HODACH RJ, SHUG AL, 1981. Systemic carnitine deficiency presenting as familial endocardial fibroelastosis. A treatable cardiomyopathy. N Engl J Med 305: 385-390.
39. WEIBEL ER, 1979. Couting in thick slices. In: Stereological methods. Vol. 1. Practical methods for biological morphometry. London: Academic Press, 46-47.
40. YORK CM, CANTRELL CR, BORUM PR, 1983. Cardiac carnitine deficiency and altered carnitine transport in cardiomyopathic hamsters. Arch Biochem Biophys 221: 526-533.