Epstein-Barr Virus-infected Akata cells are sensitive to histone deacetylase inhibitor TSA-provoked apoptosis

Journal of Biochemistry and Molecular Biology

Volumn 38, Issue 6, 2005, Pages 755-762

  Kook, Song Ho ^a   Son, Young Ok ^a   Han, Seong Kyu ^a   Lee, Hyung Soon ^a   Kim, Beom Tae ^a   Jang, Yong Suk ^a   Choi, Ki Choon ^b   Lee, Keun Soo ^a   Kim, So Soon ^a   Lim, Ji Young ^a   Jeon, Young Mi ^a   Kim, Jong Ghee ^a   Lee, Jeong Chae ^a  

^a Chonbuk National University   (South Korea)

^b Korea University College of Medicine   (South Korea)

Author keywords

Akata cells; Apoptosis induction; Epstein Barr virus; Trichostatin A

Indexed keywords

HUMAN HERPESVIRUS 4;

EID: 32644433901     PISSN: 12258687     EISSN: 12258687     Source Type: Journal    
DOI: 10.5483/bmbrep.2005.38.6.755     Document Type: Review

References (38)

1. Adrain, C. and Martin, S. J. (2001) The mitochondrial apoptosome: a killer unleashed by the cytochrome seas. Trends Biochem. Sci. 26, 390-397.
2. Ailenberg, M. and Silverman, M. (2003) Differential effects of trichostatin A on gelatinase A expression in 3T3 fibroblasts and HT-1080 fibrosarcoma cells: implications for use of TSA in cancer therapy. Biochem. Biophys. Res. Commun. 302, 181-185.
3. Annunziato, L., Amoroso, S., Pannaccione, A., Cataldi, M., Pignataro, G., D'Alessio, A., Sirabella, R., Secondo, A., Sibaud, L. and Di Renzo, G. F. (2003) Apoptosis induced in neuronal cells by oxidative stress: role played by caspases and intracellular calcium ions. Toxicol. Lett. 139, 125-133.
4. Arends, M. J., Morris, R. G. and Wyllie, A. H. (1990) Apoptosis: the role of endonucleases. Am. J. Pathol. 136, 593-608.
5. Bouillet, P. and Strasser, A. (2002) BH3-only proteins-evolutionarily conserved proapoptotic Bcl-2 family members essential for initiating programmed cell death. J. Cell Sci. 115, 1567-1574.
6. Bradford, M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
7. Chang, L. K. and Liu, S. T. (2000) Activation of the BRLF1 promoter and lytic cycle of Epstein-Barr virus by histone acetylation. Nucleic Acids Res. 28, 3918-3925.
8. Davies, A. H., Grand, R. J., Evans, F. J. and Rickinson, A. B. (1991) Induction of Epstein-Barr virus lytic cycle by tumor-promoting and non-tumor-promoting phorbol esters requires active protein kinase C. J. Virol. 65, 6838-6844.
9. Donadelli, M., Costanzo, C., Faggioli, L., Scupoli, M. T., Moore, P. S., Bassi, C., Scarpa, A. and Palmieri, M. (2003) Trichostatin A, an inhibitor of histone deacetylases, strongly suppresses growth of pancreatic adenocarcinoma cells. Mol. Carcinog. 38, 59-69.
10. Duan, H., Heckman, C. A. and Boxer, L. M. (2005) Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas. Mol. Cell Biol. 25, 1608-1619.
11. Farrell, P. J. (1995) Epstein-Barr virus immortalizing genes. Trends Microbiol. 3, 105-109.
12. wafl/cipl, Bcl-xL, ID1, ID2, ID3, CRAB2, GATA-2, hsp86 and TFIID/TAFII31 mRNA in human lung adenocarcinoma cells. Biol. Chem. 381, 107-112.
13. Epstein, M. A., Achong, B. G. and Barr, Y. M. (1964) Virus particles in cultured lymphoblasts from Burkkit's lymphoma. Lancet 1, 702-703.
14. (Wafl, Cipl, sdil) expression in Hep3B cells. Exp. Cell Res. 253, 618-628.
15. Henderson, C., Mizzau, M., Paroni, G., Maestro, R., Schneider, C. and Brancolini, C. (2003) Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA). J. Biol. Chem. 278, 12579-12589.
16. Herold, C., Ganslmayer, M., Ocker, M., Hermann, M., Geerts, A., Hahn, E. G. and Schuppan, D. (2002) The histone-deacetylase inhibitor Trichostatin A blocks proliferation and triggers apoptotic programs in hepatoma cells. J. Hepatol. 36, 233-240.
17. Kim, D. H., Jim, M. and Kwon, H. J. (2003) Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents. J. Biochem. Mol. Biol. 36, 110-119.
18. Kluck, R. M., Bossy-Wetzel, E., Green, D. R. and Newmeyer, D. D. (1997) The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 275, 1132-1136.
19. Komano, J., Sugiura, M. and Takada, K. (1998) Epstein-Barr virus contributes to the malignant phenotype and to apoptosis resistance in Burkitt's lymphoma cell line Akata. J. Virol. 72, 9150-9156.
20. Kwon, H. J., Owa, T., Hassig, C. A., Shimada, J. and Schreiber, S. L. (1998) Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase. Proc. Natl. Acad. Sci. USA 95, 3356-3361.
21. Kyrylenko, S., Kyrylenko, O., Suuronen, T. and Salminen, A. (2003) Differential regulation of the Sir2 histone deacetylase gene family by inhibitors of class I and II histone deacetylases. Cell. Mol. Life Sci. 60, 1990-1997.
22. Liu, J., Weiss, A., Durrant, D., Chi, N. W. and Lee, R. M. (2004) The cardiolipin-binding domain of Bid affects mitochondrial respiration and enhances cytochrome c release. Apoptosis 9, 533-541.
23. Medina, V., Edmonds, B., Young, G. P., James, R., Appleton, S. and Zalewski, P. D. (1997) Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. Cancer Res. 57, 3697-3707.
24. Miller, C. L., Lee, J. H., Kieff, E. and Longnecker, R. (1994) An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking. Proc. Natl. Acad. Sci. USA 91, 772-776.
25. Papeleu, P., Loyer, P., Vanhaecke, T., Elaut, G., Geerts, A., Guguen-Guillouzo, C. and Rogiers, V. (2003) Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes. J. Hepatol. 39, 374-382.
26. Patel, T., Gores, G. J. and Kaufmann, S. H. (1996) The role of proteases during apoptosis. FASEB J. 10, 587-597.
27. Qu, X. and Qing, L. (2004) Abrin induces HeLa cell apoptosis by cytochrome c release and caspase activation. J. Biochem. Mol. Biol. 37, 445-453.
28. Rahman, M. M., Kukita, A., Kukita, T., Shobuike, T., Nakamura, T. and Kohashi, O. (2003) Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages. Blood 101, 3451-3459.
29. Roh, M. S., Kim, C. W., Park, B. S., Kim, G. C., Jeong, J. H., Kwon, H. C., Suh, D. J., Cho, K. H., Yee, S. B. and Yoo, Y. H. (2004) Mechanism of histone deacetylase inhibitor Trichostatin A induced apoptosis in human osteosarcoma cells. Apoptosis 9, 583-589.
30. Ruefli, A. A., Ausserlechner, M. J., Bernhard, D., Sutton, V. R., Tainton, K. M., Kofler, R., Smyth, M. J. and Johnstone, R. W. (2001) The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species. Proc. Natl. Acad. Sci. USA 98, 10833-10838.
31. Sambucetti, L. C., Fischer, D. D., Zabludoff, S., Kwon, P. O., Chamberlin, H., Trogani, N., Xu, H. and Cohen, D. (1999) Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects. J. Biol. Chem. 274, 34940-34947.
32. Shimizu, N., Tanabe-Tochikura, A., Kuroiwa, Y. and Takada, K. (1994) Isolation of Epstein-Barr virus (EBV)-negative cell clones from the EBV-positive Burkitt's lymphoma (BL) line Akata: malignant phenotypes of BL cells are dependent on EBV. J. Virol. 68, 6069-6073.
33. Steele, V. E. (2003) Current mechanistic approaches to the chemoprevention of cancer. J. Biochem. Mol. Biol. 36, 78-81.
34. Westphal, E. M., Blackstock, W., Feng, W., Israel, B. and Kenney, S. C. (2000) Activation of lytic Epstein-Barr virus (EBV) infection by radiation and sodium butyrate in vitro and in vivo: a potential method for treating EBV positive malignancies. Cancer Res. 60, 5781-5788.
35. Wharton, W., Savell, J., Cress, W. D., Seto, E. and Pledger, W. J. (2000) Inhibition of mitogenesis in Balb/c-3T3 cells by Trichostatin A. Multiple alterations in the induction and activation of cyclin-cyclin-dependent kinase complexes. J. Biol. Chem. 275, 33981-33987.
36. 2+-dependent endonuclease in apoptosis and its inhibition by poly (ADP-ribose) polymerase. J. Biol. Chem. 275, 21302-21308.
37. Yamashita, Y., Shimada, M., Harimoto, N., Rikimura, T., Shirabe, K., Tanaka, S. and Sugimachi, K. (2003) Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells. Int. J. Cancer. 103, 572-576.
38. Zhu, W. G., Lakshmanan, R. R., Beal, M. D. and Otterson, G. A. (2001) DNA methyltransferase inhibition enhances apoptosis induced by histone deacetylase inhibitors. Cancer Res. 61, 1327-1333.