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Volumn 2, Issue 4, 2005, Pages 241-264

Production and secretion of insulin by the pancreatic β-cell;Production et sécrétion de l'insuline par la cellule β pancréatique

Author keywords

Exocytosis; Glucose metabolism; Incretins; Loop of regulation; Nervous factors; Primary stimuli; Secondary stimuli

Indexed keywords


EID: 32544449351     PISSN: 17425653     EISSN: 17425653     Source Type: Journal    
DOI: 10.1016/j.emcend.2005.07.001     Document Type: Short Survey
Times cited : (6)

References (77)
  • 1
    • 0000851240 scopus 로고
    • The structure of pig and sheep insulins
    • Brown H, Sanger F, Kitai R. The structure of pig and sheep insulins. Biochem J 1955;60:556-65.
    • (1955) Biochem J , vol.60 , pp. 556-565
    • Brown, H.1    Sanger, F.2    Kitai, R.3
  • 2
    • 0036210550 scopus 로고    scopus 로고
    • Regulation of insulin gene transcription
    • Melloul D, Marshak S, Cerasi E. Regulation of insulin gene transcription. Diabetologia 2002;45:309-26.
    • (2002) Diabetologia , vol.45 , pp. 309-326
    • Melloul, D.1    Marshak, S.2    Cerasi, E.3
  • 3
    • 0037303635 scopus 로고    scopus 로고
    • Brain insulin: Regulation, mechanisms of action and functions
    • 200
    • Gerozissis K. Brain insulin: regulation, mechanisms of action and functions. Cell Mol Neurobiol 200;23:1-25.
    • Cell Mol Neurobiol , vol.23 , pp. 1-25
    • Gerozissis, K.1
  • 6
    • 0027944249 scopus 로고
    • Transcriptional regulation of the human insulin gene Is dependent on the homeodomain protein STF1 /IPF1 acting through the CT boxes
    • Petersen HV, Serup P, Leonard J, Michelsen BK, Madsen OD. Transcriptional regulation of the human insulin gene Is dependent on the homeodomain protein STF1 /IPF1 acting through the CT boxes. Proc Natl Acad Sci USA 1994;91:10465-9.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10465-10469
    • Petersen, H.V.1    Serup, P.2    Leonard, J.3    Michelsen, B.K.4    Madsen, O.D.5
  • 7
    • 0027384997 scopus 로고
    • IPF1, a homeodomain-containing transactivator of the insulin gene
    • Ohlsson H, Karlsson K, Edlund T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 1993; 12:4251-9.
    • (1993) EMBO J , vol.12 , pp. 4251-4259
    • Ohlsson, H.1    Karlsson, K.2    Edlund, T.3
  • 8
    • 0027371952 scopus 로고
    • The helix-loop-helix transcription factor USF binds to a regulatory sequence of the human insulin gene enhancer
    • Read ML, Clark AR, Docherty K. The helix-loop-helix transcription factor USF binds to a regulatory sequence of the human insulin gene enhancer. Biochem J 1993;295:233-7.
    • (1993) Biochem J , vol.295 , pp. 233-237
    • Read, M.L.1    Clark, A.R.2    Docherty, K.3
  • 9
    • 0016245969 scopus 로고
    • Stimulation by D-glucose of cyclic adenosine 3′-5′- monophosphate accumulation and insulin release in isolated pancreatic islet of the rat
    • Grill V, Cerasi E. Stimulation by D-glucose of cyclic adenosine 3′-5′-monophosphate accumulation and insulin release in isolated pancreatic islet of the rat. J Biol Chem 1974;249:4196-201.
    • (1974) J Biol Chem , vol.249 , pp. 4196-4201
    • Grill, V.1    Cerasi, E.2
  • 10
    • 0344357096 scopus 로고
    • Glucagon like peptide i stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line
    • Drucker DJ, Philippe J, Mojsov S, Chick WL, Habener JF. Glucagon like peptide I stimulates insulin gene expression and increases cyclic AMP levels In a rat islet cell line. Proc Natl Acad Sci USA 1987;84:3434-8.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 3434-3438
    • Drucker, D.J.1    Philippe, J.2    Mojsov, S.3    Chick, W.L.4    Habener, J.F.5
  • 11
    • 0033597915 scopus 로고    scopus 로고
    • The cyclic AMP response element modulator family regulates the insulin gene transcription by interacting with transcription factor IID
    • Inada A, Someya Y, Yamada Y, Ihara Y, Kubota A, Ban N, et al. The cyclic AMP response element modulator family regulates the insulin gene transcription by interacting with transcription factor IID. J Biol Chem 1999;274:21095-103.
    • (1999) J Biol Chem , vol.274 , pp. 21095-21103
    • Inada, A.1    Someya, Y.2    Yamada, Y.3    Ihara, Y.4    Kubota, A.5    Ban, N.6
  • 12
    • 0028567837 scopus 로고
    • Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF1
    • Peers B, Leonard J, Sharma S, Teitelman G, Montminy MR. Insulin expression in pancreatic islet cells relies on cooperative interactions between the helix loop helix factor E47 and the homeobox factor STF1. Mol Endocrinol 1994; 8:1798-806.
    • (1994) Mol Endocrinol , vol.8 , pp. 1798-1806
    • Peers, B.1    Leonard, J.2    Sharma, S.3    Teitelman, G.4    Montminy, M.R.5
  • 13
    • 0029166081 scopus 로고
    • The homeodomain protein IPF1/STF1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site
    • Serup P, Petersen HV, Pedersen EE, Edlund H, Leonard J, Petersen JS, et al. The homeodomain protein IPF1/STF1 is expressed in a subset of islet cells and promotes rat insulin 1 gene expression dependent on an intact E1 helix-loop-helix factor binding site. Biochem J 1995;310(Pt3):997-1003.
    • (1995) Biochem J , vol.310 , Issue.PART 3 , pp. 997-1003
    • Serup, P.1    Petersen, H.V.2    Pedersen, E.E.3    Edlund, H.4    Leonard, J.5    Petersen, J.S.6
  • 14
    • 0031009805 scopus 로고    scopus 로고
    • Functional characterization of the transactivation properties of the PDX-1 homeodomain protein
    • Peshavaria M, Henderson E, Sharma A, Wright CV, Stein R. Functional characterization of the transactivation properties of the PDX-1 homeodomain protein. Mol Cell Biol 1997; 17:3987-96.
    • (1997) Mol Cell Biol , vol.17 , pp. 3987-3996
    • Peshavaria, M.1    Henderson, E.2    Sharma, A.3    Wright, C.V.4    Stein, R.5
  • 15
    • 0029147620 scopus 로고
    • A silencer and an adjacent positive element interact to modulate the activity of the human insulin promoter
    • Clark AR, Wilson ME, Leibiger I, Scott V, Docherty K. A silencer and an adjacent positive element interact to modulate the activity of the human insulin promoter. Eur J Biochem 1995;232:627-32.
    • (1995) Eur J Biochem , vol.232 , pp. 627-632
    • Clark, A.R.1    Wilson, M.E.2    Leibiger, I.3    Scott, V.4    Docherty, K.5
  • 16
    • 0028014549 scopus 로고
    • Nutrient regulation of insulin gene expression
    • Docherty K, Clark AR. Nutrient regulation of insulin gene expression. FASEB J 1994;8:20-7.
    • (1994) FASEB J , vol.8 , pp. 20-27
    • Docherty, K.1    Clark, A.R.2
  • 17
    • 0027154077 scopus 로고
    • Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters
    • Melloul D, Ben-Neriah Y, Cerasi E. Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters. Proc Natl Sci Acad USA 1993;90:3865-9.
    • (1993) Proc Natl Sci Acad USA , vol.90 , pp. 3865-3869
    • Melloul, D.1    Ben-Neriah, Y.2    Cerasi, E.3
  • 18
    • 0027183946 scopus 로고
    • Signals derived from glucose metabolism are required for glucose regulation of pancreatic islet GLTU2 mRNA and protein
    • Ferrer J, Gomis R, Fernandez Alvarez J, Casamitjana R, Vilardell E. Signals derived from glucose metabolism are required for glucose regulation of pancreatic islet GLTU2 mRNA and protein. Diabetes 1993;42:1273-80.
    • (1993) Diabetes , vol.42 , pp. 1273-1280
    • Ferrer, J.1    Gomis, R.2    Fernandez Alvarez, J.3    Casamitjana, R.4    Vilardell, E.5
  • 19
    • 0034637083 scopus 로고    scopus 로고
    • Glucagon like peptide 1 increases glucose-dependent activity of the homeoprotein IDX-1 transactivating domain in pancreatic beta-cells
    • Hussain MA, Habener JF. Glucagon like peptide 1 increases glucose-dependent activity of the homeoprotein IDX-1 transactivating domain in pancreatic beta-cells. Biochem Biophys Res Commun 2000;274:616-9.
    • (2000) Biochem Biophys Res Commun , vol.274 , pp. 616-619
    • Hussain, M.A.1    Habener, J.F.2
  • 21
    • 0033572844 scopus 로고    scopus 로고
    • Insulin stimulates pancreatic-duodenal homeobox factor 1 (PDX1) DNA-binding activity and insulin promoter activity in pancreatic beta cells
    • Wu H, MacFarlane WM, Tadayyon M, Arch JR, James RF, Docherty K. Insulin stimulates pancreatic-duodenal homeobox factor 1 (PDX1) DNA-binding activity and insulin promoter activity in pancreatic beta cells. Biochem J 1999;344(Pt3):813-8.
    • (1999) Biochem J , vol.344 , Issue.PART 3 , pp. 813-818
    • Wu, H.1    MacFarlane, W.M.2    Tadayyon, M.3    Arch, J.R.4    James, R.F.5    Docherty, K.6
  • 22
    • 0034730756 scopus 로고    scopus 로고
    • Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription
    • Leibiger B, Wahlander K, Berggren PO, Leibiger IB. Glucose-stimulated insulin biosynthesis depends on insulin-stimulated insulin gene transcription. J Biol Chem 2000;275:30153-6.
    • (2000) J Biol Chem , vol.275 , pp. 30153-30156
    • Leibiger, B.1    Wahlander, K.2    Berggren, P.O.3    Leibiger, I.B.4
  • 23
    • 0033582239 scopus 로고    scopus 로고
    • Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice
    • Seufert J, Kieffer TJ, Habener JF. Leptin inhibits insulin gene transcription and reverses hyperinsulinemia in leptin-deficient ob/ob mice. Proc Natl Acad Sci USA 1999;96: 674-9.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 674-679
    • Seufert, J.1    Kieffer, T.J.2    Habener, J.F.3
  • 24
    • 0031590317 scopus 로고    scopus 로고
    • Inhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptin
    • Roduit R, Thorens B. Inhibition of glucose-induced insulin secretion by long-term preexposure of pancreatic islets to leptin. FEBS Lett 1997;415:179-82.
    • (1997) FEBS Lett , vol.415 , pp. 179-182
    • Roduit, R.1    Thorens, B.2
  • 25
    • 0842284789 scopus 로고    scopus 로고
    • Leptin effects on pancreatic beta-cell gene expression and function
    • Seufert J. Leptin effects on pancreatic beta-cell gene expression and function. Diabetes 2004;53(suppl1): S152-8.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Seufert, J.1
  • 26
    • 32544432464 scopus 로고    scopus 로고
    • Signalisation intracellulaire et exocytose de l'insuline
    • Portha B. Signalisation intracellulaire et exocytose de l'insuline. MTE 2000;2:37-46.
    • (2000) MTE , vol.2 , pp. 37-46
    • Portha, B.1
  • 27
    • 0042744682 scopus 로고    scopus 로고
    • What is the role of SNARE proteins in membrane fusion?
    • Duman H, Forte JG. What is the role of SNARE proteins in membrane fusion? Am J Physiol Cell Physiol 2003;285: C237-C249.
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Duman, H.1    Forte, J.G.2
  • 28
    • 0036311144 scopus 로고    scopus 로고
    • Molecular determinants of regulated exocytosis
    • Gerber SH, Sudhof TC. Molecular determinants of regulated exocytosis. Diabetes 2002;51(suppl1):S3-S11.
    • (2002) Diabetes , vol.51 , Issue.SUPPL. 1
    • Gerber, S.H.1    Sudhof, T.C.2
  • 31
    • 0029939234 scopus 로고    scopus 로고
    • Pancreatic islet B-cell individual variability rather than subpopulation heterogeneity
    • Mercan D, Malaisse WJ. Pancreatic islet B-cell individual variability rather than subpopulation heterogeneity. Mol Cell Endocrinol 1996;118:163-71.
    • (1996) Mol Cell Endocrinol , vol.118 , pp. 163-171
    • Mercan, D.1    Malaisse, W.J.2
  • 34
    • 0035130310 scopus 로고    scopus 로고
    • Sialylated form of the neural cell adhesion molecule (NCAM): A new tool for the identification and sorting of beta-cell subpopulations with different functional activity
    • Bernard-Kargar C, Kassis N, Berthault MF, Pralong W, Ktorza A. Sialylated form of the neural cell adhesion molecule (NCAM): a new tool for the identification and sorting of beta-cell subpopulations with different functional activity. Diabetes 2001; 50(suppl1 ):S125-30.
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 1
    • Bernard-Kargar, C.1    Kassis, N.2    Berthault, M.F.3    Pralong, W.4    Ktorza, A.5
  • 37
    • 0015324585 scopus 로고
    • Decreased sensitivity of the pancreatic beta cells to glucose in predlabetic and diabetic subjects. A glucose dose-response study
    • Cerasi E, Luft R, Efendic S. Decreased sensitivity of the pancreatic beta cells to glucose in predlabetic and diabetic subjects. A glucose dose-response study. Diabetes 1972; 21:224-34.
    • (1972) Diabetes , vol.21 , pp. 224-234
    • Cerasi, E.1    Luft, R.2    Efendic, S.3
  • 38
    • 9444259786 scopus 로고    scopus 로고
    • Pathways in β-cell stimulus secretion coupling as targets for therapeutic insulin secretagogues
    • Henquin JC. Pathways in β-cell stimulus secretion coupling as targets for therapeutic insulin secretagogues. Diabetes 2004;53(suppl3):S48-58.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 3
    • Henquin, J.C.1
  • 39
    • 0034499724 scopus 로고    scopus 로고
    • Endosulfin: Novel regulators of insulin secretion
    • Bataille D. Endosulfin: novel regulators of insulin secretion. Drug News Perspect 2000; 13:453-62.
    • (2000) Drug News Perspect , vol.13 , pp. 453-462
    • Bataille, D.1
  • 40
    • 0025155731 scopus 로고
    • Physiology and pathology of the pancreatic B-cell glucose-sensor device
    • Amsterdam: Elsevier
    • Malaisse W. Physiology and pathology of the pancreatic B-cell glucose-sensor device. Diabetes, obesity and hyperlipidemia. Amsterdam: Elsevier; 1990.
    • (1990) Diabetes, Obesity and Hyperlipidemia
    • Malaisse, W.1
  • 41
    • 0021809272 scopus 로고
    • Participation of endogenous fatty acids in the secretory activity of the pancreatic B-cell
    • Malaisse WJ, Malaisse-Lagae F, Sener A, Hellerstrom C. Participation of endogenous fatty acids in the secretory activity of the pancreatic B-cell. Biochem J 1985;227:995-1002.
    • (1985) Biochem J , vol.227 , pp. 995-1002
    • Malaisse, W.J.1    Malaisse-Lagae, F.2    Sener, A.3    Hellerstrom, C.4
  • 42
    • 0023525741 scopus 로고
    • 2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion
    • 2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion. Physiol Rev 1987;67:1185-248.
    • (1987) Physiol Rev , vol.67 , pp. 1185-1248
    • Prentki, M.1    Matschinsky, F.M.2
  • 43
    • 0034668772 scopus 로고    scopus 로고
    • Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell
    • Maechler P, Wollheim CB. Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell. J Physiol 2000;529(Pt1):49-56.
    • (2000) J Physiol , vol.529 , Issue.PART 1 , pp. 49-56
    • Maechler, P.1    Wollheim, C.B.2
  • 45
    • 0023677913 scopus 로고
    • 2+ from a membrane store co-localized with pancreatic islet-cell plasma membrane
    • 2+ from a membrane store co-localized with pancreatic islet-cell plasma membrane. Biochem J 1988;253:67-72.
    • (1988) Biochem J , vol.253 , pp. 67-72
    • Dunlop, M.E.1    Larkins, R.G.2
  • 46
    • 0021645993 scopus 로고
    • 2+ in insulin secreting cells and its regulation by isolated organelles
    • 2+ in insulin secreting cells and its regulation by isolated organelles. Experientia 1984;40:1052-60.
    • (1984) Experientia , vol.40 , pp. 1052-1060
    • Prentki, M.1    Wollhelm, C.B.2
  • 47
    • 0018829711 scopus 로고
    • Glucagon release Induced by ventrolateral hypothalamic stimulation in the rat
    • Helman A, Amira R, Nicolaïdis S, Assan R. Glucagon release Induced by ventrolateral hypothalamic stimulation In the rat. Endocrinology 1980;106:1612-9.
    • (1980) Endocrinology , vol.106 , pp. 1612-1619
    • Helman, A.1    Amira, R.2    Nicolaïdis, S.3    Assan, R.4
  • 48
    • 0016705303 scopus 로고
    • Potentiation of Insulin release by glucose in man
    • Cerasi E, Grill V. Potentiation of Insulin release by glucose in man. Acta Endocrinol (Copenh) 1975;79:483-501.
    • (1975) Acta Endocrinol (Copenh) , vol.79 , pp. 483-501
    • Cerasi, E.1    Grill, V.2
  • 49
    • 0026751462 scopus 로고
    • Short-term hyperglycemia and hyperinsulinemia Improve insulin action but do not alter glucose action in normal humans
    • Kahn SE, Bergman RN, Schwartz MW, Taborsky Jr. GJ, Porte Jr. D. Short-term hyperglycemia and hyperinsulinemia Improve insulin action but do not alter glucose action In normal humans. Am J Physiol 1992;262(4Pt1):E518-E523.
    • (1992) Am J Physiol , vol.262 , Issue.4 PART 1
    • Kahn, S.E.1    Bergman, R.N.2    Schwartz, M.W.3    Taborsky Jr., G.J.4    Porte Jr., D.5
  • 50
    • 0018148325 scopus 로고
    • Immediate and time-dependent effects of glucose on insulin release from rat pancreatic tissue. Evidence for different mechanisms of action
    • Grill V, Adamson U, Cerasi E. Immediate and time-dependent effects of glucose on insulin release from rat pancreatic tissue. Evidence for different mechanisms of action. J Clin Invest 1978;61:1034-43.
    • (1978) J Clin Invest , vol.61 , pp. 1034-1043
    • Grill, V.1    Adamson, U.2    Cerasi, E.3
  • 51
    • 0035570732 scopus 로고    scopus 로고
    • Nutrient-secretion coupling in the pancreatic islet beta-cell: Recent advances
    • Rutter GA. Nutrient-secretion coupling in the pancreatic islet beta-cell: recent advances. Mol Aspects Med 2001;22: 247-84.
    • (2001) Mol Aspects Med , vol.22 , pp. 247-284
    • Rutter, G.A.1
  • 52
    • 18844480439 scopus 로고    scopus 로고
    • Junctional communication of pancreatic beta-cells contributes to the control of insulin secretion and glucose tolerance
    • Charollais A, Gjinovci A, Huarte J, Bauquis J, Nadal A, Martin F, et al. Junctional communication of pancreatic beta-cells contributes to the control of insulin secretion and glucose tolerance. J Clin Invest 2000; 106:235-43.
    • (2000) J Clin Invest , vol.106 , pp. 235-243
    • Charollais, A.1    Gjinovci, A.2    Huarte, J.3    Bauquis, J.4    Nadal, A.5    Martin, F.6
  • 53
    • 1542306440 scopus 로고    scopus 로고
    • Beta-cell crosstalk: A further dimension in the stimulus-secretion coupling of glucose-induced insulin secretion
    • Caton D, Calabrese A, Mas C, Serre-Beinier V, Wonkam A, Meda P. Beta-cell crosstalk: a further dimension in the stimulus-secretion coupling of glucose-induced insulin secretion. Diabetes Metab 2002;28(6Pt2):S45-53.
    • (2002) Diabetes Metab , vol.28 , Issue.6 PART 2
    • Caton, D.1    Calabrese, A.2    Mas, C.3    Serre-Beinier, V.4    Wonkam, A.5    Meda, P.6
  • 55
    • 0028348472 scopus 로고
    • Effect of fatty acids on insulin release: Role of chain length and degree of unsaturation
    • Opara EC, Garfinkel M, Hubbard VS, Burch WM, Akwari OE. Effect of fatty acids on insulin release: role of chain length and degree of unsaturation. Am J Physiol 1994;266(4Pt1 ): E635-E639.
    • (1994) Am J Physiol , vol.266 , Issue.4 PART 1
    • Opara, E.C.1    Garfinkel, M.2    Hubbard, V.S.3    Burch, W.M.4    Akwari, O.E.5
  • 56
    • 0030876806 scopus 로고    scopus 로고
    • The insulinotropic potency of fatty acids is Influenced profoundly by their chain length and degree of saturation
    • Stein DT, Stevenson BE, Chester MW, Basit M, Daniels MB, Turley SD, et al. The insulinotropic potency of fatty acids is Influenced profoundly by their chain length and degree of saturation. J Clin Invest 1997; 100:398-403.
    • (1997) J Clin Invest , vol.100 , pp. 398-403
    • Stein, D.T.1    Stevenson, B.E.2    Chester, M.W.3    Basit, M.4    Daniels, M.B.5    Turley, S.D.6
  • 57
    • 0036092239 scopus 로고    scopus 로고
    • Banting lecture 2001: Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes
    • McGarry JD. Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 2002;51:7-18.
    • (2002) Diabetes , vol.51 , pp. 7-18
    • McGarry, J.D.1
  • 58
    • 0034737731 scopus 로고    scopus 로고
    • Acute stimulation with long chain acylCoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells)
    • Deeney JT, Gromada J, Hoy M, Olsen HL, Rhodes CJ, Prentki M, et al. Acute stimulation with long chain acylCoA enhances exocytosis In insulin-secreting cells (HIT T-15 and NMRI beta-cells). J Biol Chem 2000;275:9363-8.
    • (2000) J Biol Chem , vol.275 , pp. 9363-9368
    • Deeney, J.T.1    Gromada, J.2    Hoy, M.3    Olsen, H.L.4    Rhodes, C.J.5    Prentki, M.6
  • 59
    • 0032825684 scopus 로고    scopus 로고
    • Receptor-mediated signaling pathways: Potential targets of modulation by dietary fatty acids
    • Hwang D, Rhee SH. Receptor-mediated signaling pathways: potential targets of modulation by dietary fatty acids. Am J Clin Nutr 1999;70:545-56.
    • (1999) Am J Clin Nutr , vol.70 , pp. 545-556
    • Hwang, D.1    Rhee, S.H.2
  • 60
    • 0028224736 scopus 로고
    • Regulation of enzymatic activity by active site fatty acylation. A new role for long chain fatty acid acylation of proteins
    • Berthiaume L, Deichaite I, Peseckis S, Resh MD. Regulation of enzymatic activity by active site fatty acylation. A new role for long chain fatty acid acylation of proteins. J Biol Chem 1994;269:6498-505.
    • (1994) J Biol Chem , vol.269 , pp. 6498-6505
    • Berthiaume, L.1    Deichaite, I.2    Peseckis, S.3    Resh, M.D.4
  • 61
    • 0032497835 scopus 로고    scopus 로고
    • Signalling functions of protein palmitoylation
    • Dunphy JT, Linder ME. Signalling functions of protein palmitoylation. Biochim Biophys Acta 1998; 1436:245-61.
    • (1998) Biochim Biophys Acta , vol.1436 , pp. 245-261
    • Dunphy, J.T.1    Linder, M.E.2
  • 62
    • 0037434991 scopus 로고    scopus 로고
    • Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40
    • Itoh Y, Kawamata Y, Harada M, Kobayashi M, Fujii R, Fukusumi S, et al. Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40. Nature 2003;422:173-6.
    • (2003) Nature , vol.422 , pp. 173-176
    • Itoh, Y.1    Kawamata, Y.2    Harada, M.3    Kobayashi, M.4    Fujii, R.5    Fukusumi, S.6
  • 63
    • 0013597788 scopus 로고
    • The amino acids-induced secretion of glucagon
    • Lefebvre P, editor. Berlin: Springer Verlag
    • Assan R, Marre M, Gormley P. The amino acids-induced secretion of glucagon. In: Lefebvre P, editor. Glucagon. Berlin: Springer Verlag; 1983. p. 19-39.
    • (1983) Glucagon , pp. 19-39
    • Assan, R.1    Marre, M.2    Gormley, P.3
  • 64
    • 32544447325 scopus 로고    scopus 로고
    • Incrétines, sécrétion d'insuline et diabète
    • Thorens B. Incrétines, sécrétion d'insuline et diabète. Med/Sci 2003; 19:8-9.
    • (2003) Med/Sci , vol.19 , pp. 8-9
    • Thorens, B.1
  • 65
    • 0021909432 scopus 로고
    • Prolonged hyperglycaemia during infusion of glucose and somatostatin Impairs pancreatic A and B-cell responses to decrements in plasma glucose in normal man
    • Dimitriatis G, Cryer P, Gerich J. Prolonged hyperglycaemia during infusion of glucose and somatostatin Impairs pancreatic A and B-cell responses to decrements In plasma glucose in normal man. Diabetologia 1985;28:63-9.
    • (1985) Diabetologia , vol.28 , pp. 63-69
    • Dimitriatis, G.1    Cryer, P.2    Gerich, J.3
  • 66
    • 0035490887 scopus 로고    scopus 로고
    • Insulin activates ATP-sensltlve K+ channels in pancreatic beta-cells through a phosphatidylinositol 3-kinase-dependent pathway
    • Kahn FA, Goforth PB, Zhang M, Satin LS. Insulin activates ATP-sensltlve K+ channels in pancreatic beta-cells through a phosphatidylinositol 3-kinase-dependent pathway. Diabetes 2001;50:2192-8.
    • (2001) Diabetes , vol.50 , pp. 2192-2198
    • Kahn, F.A.1    Goforth, P.B.2    Zhang, M.3    Satin, L.S.4
  • 67
    • 0037021433 scopus 로고    scopus 로고
    • Insulin feedback action on pancreatic beta-cell function
    • Leibiger IB, Leibiger B, Berggren PO. Insulin feedback action on pancreatic beta-cell function. FEBS Lett 2002; 532:1-6.
    • (2002) FEBS Lett , vol.532 , pp. 1-6
    • Leibiger, I.B.1    Leibiger, B.2    Berggren, P.O.3
  • 68
    • 0036068885 scopus 로고    scopus 로고
    • Miniglucagon (glucagon 19-29): A novel regulator of the pancreatic islet physiology
    • Dalle S, Fontes G, Lajoix AD, LeBrigand L, Gross R, Ribes G, et al. Miniglucagon (glucagon 19-29): a novel regulator of the pancreatic islet physiology. Diabetes 2002;51:406-12.
    • (2002) Diabetes , vol.51 , pp. 406-412
    • Dalle, S.1    Fontes, G.2    Lajoix, A.D.3    Lebrigand, L.4    Gross, R.5    Ribes, G.6
  • 69
    • 0031838744 scopus 로고    scopus 로고
    • GH signalling in pancreatic beta-cells
    • Sekine N, Wollhelm CB, Fujita T. GH signalling in pancreatic beta-cells. Endocr J 1998;45(suppl):S33-40.
    • (1998) Endocr J , vol.45 , Issue.SUPPL.
    • Sekine, N.1    Wollhelm, C.B.2    Fujita, T.3
  • 71
    • 1542284737 scopus 로고    scopus 로고
    • Adiponectin counteracts cytokine- And fatty acid-induced apoptosis in the pancreatic beta-cell line INS-1
    • Rakatzi I, Mueller H, Ritzeler O, Tennagels N, Eckel J. Adiponectin counteracts cytokine- and fatty acid-induced apoptosis In the pancreatic beta-cell line INS-1. Diabetologia 2004;47:249-58.
    • (2004) Diabetologia , vol.47 , pp. 249-258
    • Rakatzi, I.1    Mueller, H.2    Ritzeler, O.3    Tennagels, N.4    Eckel, J.5
  • 72
    • 0034001450 scopus 로고    scopus 로고
    • Autonomic regulation of islet hormone secretion-implication for health and disease
    • Ahren B. Autonomic regulation of islet hormone secretion-implication for health and disease. Diabetologia 2000;43: 393-410.
    • (2000) Diabetologia , vol.43 , pp. 393-410
    • Ahren, B.1
  • 73
    • 0022869282 scopus 로고
    • Neuropeptidergic versus cholinergic and adrenergic regulation of Islet hormone secretion
    • Ahren B, Taborsky Jr. GJ, Porte Jr. D. Neuropeptidergic versus cholinergic and adrenergic regulation of Islet hormone secretion. Diabetologia 1986;29:827-36.
    • (1986) Diabetologia , vol.29 , pp. 827-836
    • Ahren, B.1    Taborsky Jr., G.J.2    Porte Jr., D.3
  • 74
    • 0028905951 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide (PACAP) and Its receptors: Neuroendocrine and endocrine Interaction
    • Arimura A, Shioda S. Pituitary adenylate cyclase activating polypeptide (PACAP) and Its receptors: neuroendocrine and endocrine Interaction. Front Neuroendocrinol 1995; 16:53-88.
    • (1995) Front Neuroendocrinol , vol.16 , pp. 53-88
    • Arimura, A.1    Shioda, S.2
  • 75
    • 32544449744 scopus 로고
    • Molecular analysis of a2-adrenoreceptor gene expression in rat pancreatic A and B-cells
    • Chan S, Morgan N. Molecular analysis of a2-adrenoreceptor gene expression in rat pancreatic A and B-cells. Diabetologia 1995;38(suppl1):504.
    • (1995) Diabetologia , vol.38 , Issue.SUPPL. 1 , pp. 504
    • Chan, S.1    Morgan, N.2
  • 76
    • 0026778976 scopus 로고
    • Galanin and the regulation of islet hormone secretion
    • Ahren B, Lindskog S. Galanin and the regulation of islet hormone secretion. Int J Pancreatol 1992;11:147-60.
    • (1992) Int J Pancreatol , vol.11 , pp. 147-160
    • Ahren, B.1    Lindskog, S.2
  • 77
    • 0024205186 scopus 로고
    • Galanin-sympathetic neurotransmitter in endocrine pancreas?
    • Dunning B, Taborsky Jr. G. Galanin-sympathetic neurotransmitter in endocrine pancreas? Diabetes 1988;37:1157-62.
    • (1988) Diabetes , vol.37 , pp. 1157-1162
    • Dunning, B.1    Taborsky Jr., G.2


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