-
1
-
-
0023475192
-
The T cell receptor
-
Marrack P, Kappler J: The T cell receptor. Science 1987, 238:1073-1079.
-
(1987)
Science
, vol.238
, pp. 1073-1079
-
-
Marrack, P.1
Kappler, J.2
-
2
-
-
0021678703
-
Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line
-
Weiss A, Stobo JD: Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. J Exp Med 1984, 160:1284-1299.
-
(1984)
J Exp Med
, vol.160
, pp. 1284-1299
-
-
Weiss, A.1
Stobo, J.D.2
-
3
-
-
0034644505
-
Signaling takes shape in the immune system
-
Dustin ML, Chan AC: Signaling takes shape in the immune system. Cell 2000, 103:283-294.
-
(2000)
Cell
, vol.103
, pp. 283-294
-
-
Dustin, M.L.1
Chan, A.C.2
-
4
-
-
0034093737
-
Signal transduction by the TCR for antigen
-
Kane LP, Lin J, Weiss A: Signal transduction by the TCR for antigen. Curr Opin Immunol 2000, 12:242-249.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 242-249
-
-
Kane, L.P.1
Lin, J.2
Weiss, A.3
-
5
-
-
0037204932
-
Control of T cell function by positive and negative regulators
-
Singer AL, Koretzky GA: Control of T cell function by positive and negative regulators. Science 2002, 296:1639-1640.
-
(2002)
Science
, vol.296
, pp. 1639-1640
-
-
Singer, A.L.1
Koretzky, G.A.2
-
7
-
-
0032541062
-
Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell
-
Yablonski D, Kuhne MR, Kadlecek T, Weiss A: Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. Science 1998, 281:413-416.
-
(1998)
Science
, vol.281
, pp. 413-416
-
-
Yablonski, D.1
Kuhne, M.R.2
Kadlecek, T.3
Weiss, A.4
-
8
-
-
0032992072
-
Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line
-
Zhang W, Irvin BJ, Trible RP, Abraham RT, Samelson LE: Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line. Int Immunol 1999, 11:943-950.
-
(1999)
Int Immunol
, vol.11
, pp. 943-950
-
-
Zhang, W.1
Irvin, B.J.2
Trible, R.P.3
Abraham, R.T.4
Samelson, L.E.5
-
9
-
-
0030797223
-
Tetracycline-controlled transcription in eukaryotes: Novel transactivators with graded transactivation potential
-
Baron U, Gossen M, Bujard H: Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential. Nucleic Acids Res 1997, 25:2723-2729.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 2723-2729
-
-
Baron, U.1
Gossen, M.2
Bujard, H.3
-
10
-
-
0030046923
-
Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling
-
Qian D, Mollenauer MN, Weiss A: Dominant-negative zeta-associated protein 70 inhibits T cell antigen receptor signaling. J Exp Med 1996, 183:611-620.
-
(1996)
J Exp Med
, vol.183
, pp. 611-620
-
-
Qian, D.1
Mollenauer, M.N.2
Weiss, A.3
-
11
-
-
0035124549
-
T cell receptor signalling
-
Lin J, Weiss A: T cell receptor signalling. J Cell Sci 2001, 114:243-244.
-
(2001)
J Cell Sci
, vol.114
, pp. 243-244
-
-
Lin, J.1
Weiss, A.2
-
12
-
-
0026705903
-
Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor
-
Straus DB, Weiss A: Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 1992, 70:585-593.
-
(1992)
Cell
, vol.70
, pp. 585-593
-
-
Straus, D.B.1
Weiss, A.2
-
13
-
-
0025835006
-
T-cell antigen receptor ligation induces tyrosine phosphorylation of phospholipase C-gamma 1
-
Secrist JP, Karnitz L, Abraham RT: T-cell antigen receptor ligation induces tyrosine phosphorylation of phospholipase C-gamma 1. J Biol Chem 1991, 266:12135-12139.
-
(1991)
J Biol Chem
, vol.266
, pp. 12135-12139
-
-
Secrist, J.P.1
Karnitz, L.2
Abraham, R.T.3
-
14
-
-
0034461022
-
Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: Reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line
-
Irvin BJ, Williams BL, Nilson AE, Maynor HO, Abraham RT: Pleiotropic contributions of phospholipase C-gamma1 (PLC-gamma1) to T-cell antigen receptor-mediated signaling: reconstitution studies of a PLC-gamma1-deficient Jurkat T-cell line. Mol Cell Biol 2000, 20:9149-9161.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9149-9161
-
-
Irvin, B.J.1
Williams, B.L.2
Nilson, A.E.3
Maynor, H.O.4
Abraham, R.T.5
-
15
-
-
0025311299
-
An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors
-
Hla T, Maciag T: An abundant transcript induced in differentiating human endothelial cells encodes a polypeptide with structural similarities to G-protein-coupled receptors. J Biol Chem 1990, 265:9308-9313.
-
(1990)
J Biol Chem
, vol.265
, pp. 9308-9313
-
-
Hla, T.1
Maciag, T.2
-
16
-
-
0032489574
-
Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1
-
Lee MJ, Van Brocklyn JR, Thangada S, Liu CH, Hand AR, Menzeleev R, Spiegel S, Hla T: Sphingosine-1-phosphate as a ligand for the G protein-coupled receptor EDG-1. Science 1998, 279:1552-1555.
-
(1998)
Science
, vol.279
, pp. 1552-1555
-
-
Lee, M.J.1
Van Brocklyn, J.R.2
Thangada, S.3
Liu, C.H.4
Hand, A.R.5
Menzeleev, R.6
Spiegel, S.7
Hla, T.8
-
17
-
-
0032538463
-
2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition
-
2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition. J Biol Chem 1998, 273:27104-27110.
-
(1998)
J Biol Chem
, vol.273
, pp. 27104-27110
-
-
Okamoto, H.1
Takuwa, N.2
Gonda, K.3
Okazaki, H.4
Chang, K.5
Yatomi, Y.6
Shigematsu, H.7
Takuwa, Y.8
-
18
-
-
0029805324
-
Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways
-
Lim L, Manser E, Leung T, Hall C: Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways. Eur J Biochem 1996, 242:171-185.
-
(1996)
Eur J Biochem
, vol.242
, pp. 171-185
-
-
Lim, L.1
Manser, E.2
Leung, T.3
Hall, C.4
-
19
-
-
0038554077
-
Biology of the p21-activated kinases
-
Bokoch GM: Biology of the p21-activated kinases. Annu Rev Biochem 2003, 72:743-781.
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 743-781
-
-
Bokoch, G.M.1
-
20
-
-
0029056399
-
A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20
-
Martin GA, Bollag G, McCormick F, Abo A: A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20. EMBO J 1995, 14:1970-1978.
-
(1995)
EMBO J
, vol.14
, pp. 1970-1978
-
-
Martin, G.A.1
Bollag, G.2
McCormick, F.3
Abo, A.4
-
21
-
-
0028842508
-
Identification and molecular cloning of a p21 cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets
-
Teo M, Manser E, Lim L: Identification and molecular cloning of a p21 cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets. J Biol Chem 1995, 270:26690-26697.
-
(1995)
J Biol Chem
, vol.270
, pp. 26690-26697
-
-
Teo, M.1
Manser, E.2
Lim, L.3
-
22
-
-
0030918572
-
Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
-
Rudel T, Bokoch GM: Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 1997, 276:1571-1574.
-
(1997)
Science
, vol.276
, pp. 1571-1574
-
-
Rudel, T.1
Bokoch, G.M.2
-
23
-
-
0031907887
-
p21-activated kinase (PAK) is required for Fas-induced JNK activation in Jurkat cells
-
Rudel T, Zenke FT, Chuang TH, Bokoch GM: p21-activated kinase (PAK) is required for Fas-induced JNK activation in Jurkat cells. J Immunol 1998, 160:7-11.
-
(1998)
J Immunol
, vol.160
, pp. 7-11
-
-
Rudel, T.1
Zenke, F.T.2
Chuang, T.H.3
Bokoch, G.M.4
-
24
-
-
0032211713
-
Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76
-
Bubeck Wardenburg J, Pappu R, Bu JY, Mayer B, Chernoff J, Straus D, Chan AC: Regulation of PAK activation and the T cell cytoskeleton by the linker protein SLP-76. Immunity 1998, 9:607-616.
-
(1998)
Immunity
, vol.9
, pp. 607-616
-
-
Bubeck Wardenburg, J.1
Pappu, R.2
Bu, J.Y.3
Mayer, B.4
Chernoff, J.5
Straus, D.6
Chan, A.C.7
-
25
-
-
0032188987
-
A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK
-
Yablonski D, Kane LP, Qian D, Weiss A: A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK. EMBO J 1998, 17:5647-5657.
-
(1998)
EMBO J
, vol.17
, pp. 5647-5657
-
-
Yablonski, D.1
Kane, L.P.2
Qian, D.3
Weiss, A.4
-
26
-
-
0026644391
-
High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains
-
Margolis B, Silvennoinen O, Comoglio F, Roonprapunt C, Skolnik E, Ullrich A, Schlessinger J: High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains. Proc Natl Acad Sci USA 1992, 89:8894-8898.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 8894-8898
-
-
Margolis, B.1
Silvennoinen, O.2
Comoglio, F.3
Roonprapunt, C.4
Skolnik, E.5
Ullrich, A.6
Schlessinger, J.7
-
27
-
-
0035473462
-
The Grb7 family proteins: Structure, interactions with other signaling molecules and potential cellular functions
-
Han DC, Shen TL, Guan JL: The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions. Oncogene 2001, 20:6315-6321.
-
(2001)
Oncogene
, vol.20
, pp. 6315-6321
-
-
Han, D.C.1
Shen, T.L.2
Guan, J.L.3
-
28
-
-
0034266806
-
RING finger proteins: Mediators of ubiquitin ligase activity
-
Joazeiro CA, Weissman AM: RING finger proteins: mediators of ubiquitin ligase activity. Cell 2000, 102:549-552.
-
(2000)
Cell
, vol.102
, pp. 549-552
-
-
Joazeiro, C.A.1
Weissman, A.M.2
-
29
-
-
0036144763
-
Regulatory functions of ubiquitination in the immune system
-
Ben-Neriah Y: Regulatory functions of ubiquitination in the immune system. Nat Immunol 2002, 3:20-26.
-
(2002)
Nat Immunol
, vol.3
, pp. 20-26
-
-
Ben-Neriah, Y.1
-
30
-
-
0034738464
-
Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase
-
Sawasdikosol S, Pratt JC, Meng W, Eck MJ, Burakoff SJ: Adapting to multiple personalities: Cbl is also a RING finger ubiquitin ligase. Biochim Biophys Acta 2000, 1471:M1-M12.
-
(2000)
Biochim Biophys Acta
, vol.1471
-
-
Sawasdikosol, S.1
Pratt, J.C.2
Meng, W.3
Eck, M.J.4
Burakoff, S.J.5
-
31
-
-
0033178733
-
Quantitative measurement of mast cell degranulation using a novel flow cytometric annexin-V binding assay
-
Demo SD, Masuda E, Rossi AB, Throndset BT, Gerard AL, Chan EH, Armstrong RJ, Fox BP, Lorens JB, Payan DG, et al.: Quantitative measurement of mast cell degranulation using a novel flow cytometric annexin-V binding assay. Cytometry 1999, 36:340-348.
-
(1999)
Cytometry
, vol.36
, pp. 340-348
-
-
Demo, S.D.1
Masuda, E.2
Rossi, A.B.3
Throndset, B.T.4
Gerard, A.L.5
Chan, E.H.6
Armstrong, R.J.7
Fox, B.P.8
Lorens, J.B.9
Payan, D.G.10
-
32
-
-
0036311889
-
Sphingosine 1 phosphate induces the chemotaxis of human natural killer cells. Role for heterotrimeric G proteins and phosphoinositide 3 kinases
-
Kveberg L, Bryceson Y, Inngjerdingen M, Rolstad B, Maghazachi AA: Sphingosine 1 phosphate induces the chemotaxis of human natural killer cells. Role for heterotrimeric G proteins and phosphoinositide 3 kinases. Eur J Immunol 2002, 32:1856-1864.
-
(2002)
Eur J Immunol
, vol.32
, pp. 1856-1864
-
-
Kveberg, L.1
Bryceson, Y.2
Inngjerdingen, M.3
Rolstad, B.4
Maghazachi, A.A.5
-
33
-
-
0036551246
-
Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses
-
Idzko M, Panther E, Corinti S, Morelli A, Ferrari D, Herouy Y, Dichmann S, Mockenhaupt M, Gebicke-Haerter P, Di Virgilio F, et al.: Sphingosine 1-phosphate induces chemotaxis of immature and modulates cytokine-release in mature human dendritic cells for emergence of Th2 immune responses. FASEB J 2002, 16:625-627.
-
(2002)
FASEB J
, vol.16
, pp. 625-627
-
-
Idzko, M.1
Panther, E.2
Corinti, S.3
Morelli, A.4
Ferrari, D.5
Herouy, Y.6
Dichmann, S.7
Mockenhaupt, M.8
Gebicke-Haerter, P.9
Di Virgilio, F.10
-
34
-
-
0030614746
-
Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains
-
Frantz JD, Giorgetti-Peraldi S, Ottinger EA, Shoelson SE: Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains. J Biol Chem 1997, 272:2659-2667.
-
(1997)
J Biol Chem
, vol.272
, pp. 2659-2667
-
-
Frantz, J.D.1
Giorgetti-Peraldi, S.2
Ottinger, E.A.3
Shoelson, S.E.4
-
35
-
-
0037077308
-
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
-
Brinkmann V, Davis MD, Heise CE, Albert R, Cottens S, Hof R, Bruns C, Prieschl E, Baumruker T, Hiestand P, et al.: The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J Biol Chem 2002, 277:21453-21457.
-
(2002)
J Biol Chem
, vol.277
, pp. 21453-21457
-
-
Brinkmann, V.1
Davis, M.D.2
Heise, C.E.3
Albert, R.4
Cottens, S.5
Hof, R.6
Bruns, C.7
Prieschl, E.8
Baumruker, T.9
Hiestand, P.10
-
36
-
-
0037066466
-
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
-
Mandala S, Hajdu R, Bergstrom J, Quackenbush E, Xie J, Milligan J, Thornton R, Shei GJ, Card D, Keohane C, et al.: Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists. Science 2002, 296:346-349.
-
(2002)
Science
, vol.296
, pp. 346-349
-
-
Mandala, S.1
Hajdu, R.2
Bergstrom, J.3
Quackenbush, E.4
Xie, J.5
Milligan, J.6
Thornton, R.7
Shei, G.J.8
Card, D.9
Keohane, C.10
-
37
-
-
0028287296
-
The role of Raf-1 in the regulation of extracellular signal-regulated kinase 2 by the T cell antigen receptor
-
Izquierdo M, Bowden S, Cantrell D: The role of Raf-1 in the regulation of extracellular signal-regulated kinase 2 by the T cell antigen receptor. J Exp Med 1994, 180:401-406.
-
(1994)
J Exp Med
, vol.180
, pp. 401-406
-
-
Izquierdo, M.1
Bowden, S.2
Cantrell, D.3
-
38
-
-
0027376035
-
Rapid activation of C-Raf-1 after stimulation of the T-cell receptor or the muscarinic receptor type 1 in resting T cells
-
Siegel JN, June CH, Yamada H, Rapp UR, Samelson LE: Rapid activation of C-Raf-1 after stimulation of the T-cell receptor or the muscarinic receptor type 1 in resting T cells. J Immunol 1993, 151:4116-4127.
-
(1993)
J Immunol
, vol.151
, pp. 4116-4127
-
-
Siegel, J.N.1
June, C.H.2
Yamada, H.3
Rapp, U.R.4
Samelson, L.E.5
-
39
-
-
0028227284
-
SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: The guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T cell antigen receptor-activated tyrosine kinases
-
Reif K, Buday L, Downward J, Cantrell DA: SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: the guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T cell antigen receptor-activated tyrosine kinases. J Biol Chem 1994, 269:14081-14087.
-
(1994)
J Biol Chem
, vol.269
, pp. 14081-14087
-
-
Reif, K.1
Buday, L.2
Downward, J.3
Cantrell, D.A.4
-
40
-
-
0028245832
-
A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells
-
Buday L, Egan SE, Rodriguez Viciana P, Cantrell DA, Downward J: A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells. J Biol Chem 1994, 269:9019-9023.
-
(1994)
J Biol Chem
, vol.269
, pp. 9019-9023
-
-
Buday, L.1
Egan, S.E.2
Rodriguez Viciana, P.3
Cantrell, D.A.4
Downward, J.5
-
41
-
-
0032750417
-
Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex
-
Brown A, Wang X, Sawai E, Cheng-Mayer C: Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex. J Virol 1999, 73:9899-9907.
-
(1999)
J Virol
, vol.73
, pp. 9899-9907
-
-
Brown, A.1
Wang, X.2
Sawai, E.3
Cheng-Mayer, C.4
-
42
-
-
0033518291
-
Identification of the Nef-associated kinase as p21-activated kinase 2
-
Renkema GH, Manninen A, Mann DA, Harris M, Saksela K: Identification of the Nef-associated kinase as p21-activated kinase 2. Curr Biol 1999, 9:1407-1410.
-
(1999)
Curr Biol
, vol.9
, pp. 1407-1410
-
-
Renkema, G.H.1
Manninen, A.2
Mann, D.A.3
Harris, M.4
Saksela, K.5
-
43
-
-
0034469146
-
Lentivirus Nef specifically activates Pak2
-
Arora VK, Molina RP, Foster JL, Blakemore JL, Chernoff J, Fredericksen BL, Garcia JV: Lentivirus Nef specifically activates Pak2. J Virol 2000, 74:11081-11087.
-
(2000)
J Virol
, vol.74
, pp. 11081-11087
-
-
Arora, V.K.1
Molina, R.P.2
Foster, J.L.3
Blakemore, J.L.4
Chernoff, J.5
Fredericksen, B.L.6
Garcia, J.V.7
-
44
-
-
0035711333
-
The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics
-
Lorens JB, Sousa C, Bennett MK, Molineaux SM, Payan DG: The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics. Curr Opin Biotechnol 2001, 12:613-621.
-
(2001)
Curr Opin Biotechnol
, vol.12
, pp. 613-621
-
-
Lorens, J.B.1
Sousa, C.2
Bennett, M.K.3
Molineaux, S.M.4
Payan, D.G.5
-
45
-
-
0035158568
-
Dominant effector genetics in mammalian cells
-
Xu X, Leo C, Jang Y, Chan E, Padilla D, Huang BC, Lin T, Gururaja T, Hitoshi Y, Lorens JB, et al.: Dominant effector genetics in mammalian cells. Nat Genet 2001, 27:23-29.
-
(2001)
Nat Genet
, vol.27
, pp. 23-29
-
-
Xu, X.1
Leo, C.2
Jang, Y.3
Chan, E.4
Padilla, D.5
Huang, B.C.6
Lin, T.7
Gururaja, T.8
Hitoshi, Y.9
Lorens, J.B.10
-
46
-
-
0035173040
-
Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signaling
-
Holland SJ, Liao XC, Mendenhall MK, Zhou X, Pardo J, Chu P, Spencer C, Fu A, Sheng N, Yu P, et al.: Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signaling. J Exp Med 2001, 194:1263-1276.
-
(2001)
J Exp Med
, vol.194
, pp. 1263-1276
-
-
Holland, S.J.1
Liao, X.C.2
Mendenhall, M.K.3
Zhou, X.4
Pardo, J.5
Chu, P.6
Spencer, C.7
Fu, A.8
Sheng, N.9
Yu, P.10
-
47
-
-
0037020080
-
Retrovirally delivered random cyclic peptide libraries yield inhibitors of interleukin-4 signaling in human B cells
-
Kinsella TM, Ohashi CT, Harder AG, Yam GC, Li W, Peelle B, Pali ES, Bennett MK, Molineaux SM, Anderson DA, et al.: Retrovirally delivered random cyclic peptide libraries yield inhibitors of interleukin-4 signaling in human B cells. J Biol Chem 2002, 277:37512-37518.
-
(2002)
J Biol Chem
, vol.277
, pp. 37512-37518
-
-
Kinsella, T.M.1
Ohashi, C.T.2
Harder, A.G.3
Yam, G.C.4
Li, W.5
Peelle, B.6
Pali, E.S.7
Bennett, M.K.8
Molineaux, S.M.9
Anderson, D.A.10
-
48
-
-
0034183694
-
Retroviral delivery of peptide modulators of cellular functions
-
Lorens JB, Bennett MK, Pearsall DM, Throndset WR, Rossi AB, Armstrong RJ, Fox BP, Chan EH, Luo Y, Masuda E, et al.: Retroviral delivery of peptide modulators of cellular functions. Mol Ther 2000, 1:438-447.
-
(2000)
Mol Ther
, vol.1
, pp. 438-447
-
-
Lorens, J.B.1
Bennett, M.K.2
Pearsall, D.M.3
Throndset, W.R.4
Rossi, A.B.5
Armstrong, R.J.6
Fox, B.P.7
Chan, E.H.8
Luo, Y.9
Masuda, E.10
-
49
-
-
0003059314
-
Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems
-
10.17C. Edited by Coligan RCJE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W. Hoboken, NJ: John Wiley and Sons
-
Swift SE, Lorens JB, Achacoso P, Nolan GP: Rapid production of retroviruses for efficient gene delivery to mammalian cells using 293T cell-based systems. In Current Protocols in Immunology, vol 10.17C. Edited by Coligan RCJE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W. Hoboken, NJ: John Wiley and Sons; 2000:1-17.
-
(2000)
Current Protocols in Immunology
, pp. 1-17
-
-
Swift, S.E.1
Lorens, J.B.2
Achacoso, P.3
Nolan, G.P.4
-
50
-
-
0032055478
-
Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells
-
Hitoshi Y, Lorens J, Kitada SI, Fisher J, LaBarge M, Ring HZ, Francke U, Reed JC, Kinoshita S, Nolan GP: Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells. Immunity 1998, 8:461-471.
-
(1998)
Immunity
, vol.8
, pp. 461-471
-
-
Hitoshi, Y.1
Lorens, J.2
Kitada, S.I.3
Fisher, J.4
LaBarge, M.5
Ring, H.Z.6
Francke, U.7
Reed, J.C.8
Kinoshita, S.9
Nolan, G.P.10
-
51
-
-
0242523599
-
-
GenBank [http://www.ncbi.nlm.nih.gov/Genbank/]
-
-
-
-
52
-
-
0033638003
-
On the dynamics of TCR:CD3 complex cell surface expression and down-modulation
-
Liu H, Rhodes M, Wiest DL, Vignali DA: On the dynamics of TCR:CD3 complex cell surface expression and down-modulation. Immunity 2000, 13:665-675.
-
(2000)
Immunity
, vol.13
, pp. 665-675
-
-
Liu, H.1
Rhodes, M.2
Wiest, D.L.3
Vignali, D.A.4
-
53
-
-
0028321540
-
Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex
-
Law CL, Sidorenko SP, Chandran KA, Draves KE, Chan AC, Weiss A, Edelhoff S, Disteche CM, Clark EA: Molecular cloning of human Syk. A B cell protein-tyrosine kinase associated with the surface immunoglobulin M-B cell receptor complex. J Biol Chem 1994, 269:12310-12319.
-
(1994)
J Biol Chem
, vol.269
, pp. 12310-12319
-
-
Law, C.L.1
Sidorenko, S.P.2
Chandran, K.A.3
Draves, K.E.4
Chan, A.C.5
Weiss, A.6
Edelhoff, S.7
Disteche, C.M.8
Clark, E.A.9
-
54
-
-
0031912097
-
Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: Reconstitution studies in a ZAP-70-deficient Jurkat T-cell line
-
Williams BL, Schreiber KL, Zhang W, Wange RL, Samelson LE, Leibson PJ, Abraham RT: Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line. Mol Cell Biol 1998, 18:1388-1399.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1388-1399
-
-
Williams, B.L.1
Schreiber, K.L.2
Zhang, W.3
Wange, R.L.4
Samelson, L.E.5
Leibson, P.J.6
Abraham, R.T.7
-
55
-
-
0028838262
-
Syk mutation in Jurkat E6-derived clones results in lack of p72syk expression
-
Fargnoli J, Burkhardt AL, Laverty M, Kut SA, van Oers NS, Weiss A, Bolen JB: Syk mutation in Jurkat E6-derived clones results in lack of p72syk expression. J Biol Chem 1995, 270:26533-26537.
-
(1995)
J Biol Chem
, vol.270
, pp. 26533-26537
-
-
Fargnoli, J.1
Burkhardt, A.L.2
Laverty, M.3
Kut, S.A.4
Van Oers, N.S.5
Weiss, A.6
Bolen, J.B.7
-
56
-
-
0030764557
-
Severe defects in immunity and hematopoiesis caused by SHP-1 protein-tyrosine-phosphatase deficiency
-
Shultz LD, Rajan TV, Greiner DL: Severe defects in immunity and hematopoiesis caused by SHP-1 protein-tyrosine-phosphatase deficiency. Trends Biotechnol 1997, 15:302-307.
-
(1997)
Trends Biotechnol
, vol.15
, pp. 302-307
-
-
Shultz, L.D.1
Rajan, T.V.2
Greiner, D.L.3
-
57
-
-
0034613151
-
Immune inhibitory receptors
-
Ravetch JV, Lanier LL: Immune inhibitory receptors. Science 2000, 290:84-89.
-
(2000)
Science
, vol.290
, pp. 84-89
-
-
Ravetch, J.V.1
Lanier, L.L.2
-
58
-
-
0034635505
-
Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1
-
Yang J, Cheng Z, Niu T, Liang X, Zhao ZJ, Zhou GW: Structural basis for substrate specificity of protein-tyrosine phosphatase SHP-1. J Biol Chem 2000, 275:4066-4071.
-
(2000)
J Biol Chem
, vol.275
, pp. 4066-4071
-
-
Yang, J.1
Cheng, Z.2
Niu, T.3
Liang, X.4
Zhao, Z.J.5
Zhou, G.W.6
-
59
-
-
0342313755
-
Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation
-
Brdicka T, Pavlistova D, Leo A, Bruyns E, Korinek V, Angelisova P, Scherer J, Shevchenko A, Hilgert I, Cerny J, et al.: Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation. J Exp Med 2000, 191:1591-1604.
-
(2000)
J Exp Med
, vol.191
, pp. 1591-1604
-
-
Brdicka, T.1
Pavlistova, D.2
Leo, A.3
Bruyns, E.4
Korinek, V.5
Angelisova, P.6
Scherer, J.7
Shevchenko, A.8
Hilgert, I.9
Cerny, J.10
-
60
-
-
0034720166
-
Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases
-
Kawabuchi M, Satomi Y, Takao T, Shimonishi Y, Nada S, Nagai K, Tarakhovsky A, Okada M: Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases. Nature 2000, 404:999-1003.
-
(2000)
Nature
, vol.404
, pp. 999-1003
-
-
Kawabuchi, M.1
Satomi, Y.2
Takao, T.3
Shimonishi, Y.4
Nada, S.5
Nagai, K.6
Tarakhovsky, A.7
Okada, M.8
-
61
-
-
0032498231
-
LAT: The ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
-
Zhang W, Sloan-Lancaster J, Kitchen J, Trible RP, Samelson LE: LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998, 92:83-92.
-
(1998)
Cell
, vol.92
, pp. 83-92
-
-
Zhang, W.1
Sloan-Lancaster, J.2
Kitchen, J.3
Trible, R.P.4
Samelson, L.E.5
-
62
-
-
0035800835
-
Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts
-
Torgersen KM, Vang T, Abrahamsen H, Yaqub S, Horejsi V, Schraven B, Rolstad B, Mustelin T, Tasken K: Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts. J Biol Chem 2001, 276:29313-29318.
-
(2001)
J Biol Chem
, vol.276
, pp. 29313-29318
-
-
Torgersen, K.M.1
Vang, T.2
Abrahamsen, H.3
Yaqub, S.4
Horejsi, V.5
Schraven, B.6
Rolstad, B.7
Mustelin, T.8
Tasken, K.9
-
63
-
-
0036143017
-
Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases
-
Hermiston ML, Xu Z, Majeti R, Weiss A: Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases. J Clin Invest 2002, 109:9-14.
-
(2002)
J Clin Invest
, vol.109
, pp. 9-14
-
-
Hermiston, M.L.1
Xu, Z.2
Majeti, R.3
Weiss, A.4
-
64
-
-
0037080345
-
Cutting edge: Negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly
-
Itoh K, Sakakibara M, Yamasaki S, Takeuchi A, Arase H, Miyazaki M, Nakajima N, Okada M, Saito T: Cutting edge: negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly. J Immunol 2002, 168:541-544.
-
(2002)
J Immunol
, vol.168
, pp. 541-544
-
-
Itoh, K.1
Sakakibara, M.2
Yamasaki, S.3
Takeuchi, A.4
Arase, H.5
Miyazaki, M.6
Nakajima, N.7
Okada, M.8
Saito, T.9
-
65
-
-
0034667593
-
Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
-
Kolch W: Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem J 2000, 351:289-305.
-
(2000)
Biochem J
, vol.351
, pp. 289-305
-
-
Kolch, W.1
-
66
-
-
0028287296
-
The role of Raf-1 in the regulation of extracellular signal-regulated kinase 2 by the T cell antigen receptor
-
Izquierdo M, Bowden S, Cantrell D: The role of Raf-1 in the regulation of extracellular signal-regulated kinase 2 by the T cell antigen receptor. J Exp Med 1994, 180:401-406.
-
(1994)
J Exp Med
, vol.180
, pp. 401-406
-
-
Izquierdo, M.1
Bowden, S.2
Cantrell, D.3
-
67
-
-
0028302767
-
The T-cell antigen receptor utilizes Lck, Raf-1, and MEK-1 for activating mitogen-activated protein kinase. Evidence for the existence of a second protein kinase C-dependent pathway in an Lck-negative Jurkat cell mutant
-
Gupta S, Weiss A, Kumar G, Wang S, Nel A: The T-cell antigen receptor utilizes Lck, Raf-1, and MEK-1 for activating mitogen-activated protein kinase. Evidence for the existence of a second protein kinase C-dependent pathway in an Lck-negative Jurkat cell mutant. J Biol Chem 1994, 269:17349-17357.
-
(1994)
J Biol Chem
, vol.269
, pp. 17349-17357
-
-
Gupta, S.1
Weiss, A.2
Kumar, G.3
Wang, S.4
Nel, A.5
-
68
-
-
0025979335
-
Raf-1 protein kinase is required for growth of induced NIH/3T3 cells
-
Kolch W, Heidecker G, Lloyd P, Rapp UR: Raf-1 protein kinase is required for growth of induced NIH/3T3 cells. Nature 1991, 349:426-428.
-
(1991)
Nature
, vol.349
, pp. 426-428
-
-
Kolch, W.1
Heidecker, G.2
Lloyd, P.3
Rapp, U.R.4
-
69
-
-
0027237273
-
A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21 ras
-
Schaap D, van der Wal J, Howe LR, Marshall CJ, van Blitterswijk WJ: A dominant-negative mutant of raf blocks mitogen-activated protein kinase activation by growth factors and oncogenic p21 ras. J Biol Chem 1993, 268:20232-20236.
-
(1993)
J Biol Chem
, vol.268
, pp. 20232-20236
-
-
Schaap, D.1
Van Der Wal, J.2
Howe, L.R.3
Marshall, C.J.4
Van Blitterswijk, W.J.5
-
70
-
-
0024359515
-
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family
-
Cool DE, Tonks NK, Charbonneau H, Walsh KA, Fischer EH, Krebs EG: cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family. Proc Natl Acad Sci USA 1989, 86:5257-5261.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 5257-5261
-
-
Cool, D.E.1
Tonks, N.K.2
Charbonneau, H.3
Walsh, K.A.4
Fischer, E.H.5
Krebs, E.G.6
-
71
-
-
0030703139
-
The noncatalytic C-terminal segment of the T cell protein tyrosine phosphatase regulates activity via an intramolecular mechanism
-
Hao L, Tiganis T, Tonks NK, Charbonneau H: The noncatalytic C-terminal segment of the T cell protein tyrosine phosphatase regulates activity via an intramolecular mechanism. J Biol Chem 1997, 272:29322-29329.
-
(1997)
J Biol Chem
, vol.272
, pp. 29322-29329
-
-
Hao, L.1
Tiganis, T.2
Tonks, N.K.3
Charbonneau, H.4
-
72
-
-
0028350053
-
Expression cloning and characterization of a human IL-10 receptor
-
Liu Y, Wei SH, Ho AS, de Waal Malefyt R, Moore KW: Expression cloning and characterization of a human IL-10 receptor. J Immunol 1994, 152:1821-1829.
-
(1994)
J Immunol
, vol.152
, pp. 1821-1829
-
-
Liu, Y.1
Wei, S.H.2
Ho, A.S.3
De Waal Malefyt, R.4
Moore, K.W.5
-
73
-
-
0024382716
-
The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GP1a): Homology to other integrins and the presence of a possible collagen-binding domain
-
Takada Y, Hemler ME: The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GP1a): homology to other integrins and the presence of a possible collagen-binding domain. J Cell Biol 1989, 109:397-407.
-
(1989)
J Cell Biol
, vol.109
, pp. 397-407
-
-
Takada, Y.1
Hemler, M.E.2
-
74
-
-
0030865394
-
Integrins and inside-out signal transduction: Converging signals from PKC and PIP3
-
Kolanus W, Seed B: Integrins and inside-out signal transduction: converging signals from PKC and PIP3. Curr Opin Cell Biol 1997, 9:725-731.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 725-731
-
-
Kolanus, W.1
Seed, B.2
-
75
-
-
0035937128
-
The molecular adapter SLP-76 relays signals from platelet integrin alpha11bbeta3 to the actin cytoskeleton
-
Obergfell A, Judd BA, del Pozo MA, Schwartz MA, Koretzky GA, Shattil SJ: The molecular adapter SLP-76 relays signals from platelet integrin alpha11bbeta3 to the actin cytoskeleton. J Biol Chem 2001, 276:5916-5923.
-
(2001)
J Biol Chem
, vol.276
, pp. 5916-5923
-
-
Obergfell, A.1
Judd, B.A.2
Del Pozo, M.A.3
Schwartz, M.A.4
Koretzky, G.A.5
Shattil, S.J.6
-
76
-
-
0035929222
-
Coupling of the TCR to integrin activation by Slap-130/Fyb
-
Peterson EJ, Woods ML, Dmowski SA, Derimanov G, Jordan MS, Wu JN, Myung PS, Liu QH, Pribila JT, Freedman BD, et al.: Coupling of the TCR to integrin activation by Slap-130/Fyb. Science 2001, 293:2263-2265.
-
(2001)
Science
, vol.293
, pp. 2263-2265
-
-
Peterson, E.J.1
Woods, M.L.2
Dmowski, S.A.3
Derimanov, G.4
Jordan, M.S.5
Wu, J.N.6
Myung, P.S.7
Liu, Q.H.8
Pribila, J.T.9
Freedman, B.D.10
-
77
-
-
0026453395
-
itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2
-
Siliciano JD, Morrow TA, Desiderio SV: itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2. Proc Natl Acad Sci USA 1992, 89:11194-11198.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11194-11198
-
-
Siliciano, J.D.1
Morrow, T.A.2
Desiderio, S.V.3
-
78
-
-
13344270890
-
Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk
-
Liao XC, Littman DR: Altered T cell receptor signaling and disrupted T cell development in mice lacking Itk. Immunity 1995, 3:757-769.
-
(1995)
Immunity
, vol.3
, pp. 757-769
-
-
Liao, X.C.1
Littman, D.R.2
-
79
-
-
0035868761
-
A novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptor
-
Woods ML, Kivens WJ, Adelsman MA, Qiu Y, August A, Shimizu Y: A novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptor. EMBO J 2001, 20:1232-1244.
-
(2001)
EMBO J
, vol.20
, pp. 1232-1244
-
-
Woods, M.L.1
Kivens, W.J.2
Adelsman, M.A.3
Qiu, Y.4
August, A.5
Shimizu, Y.6
-
80
-
-
0033581478
-
Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail
-
Ivaska J, Reunanen H, Westermarck J, Koivisto L, Kahari VM, Heino J: Integrin alpha2beta1 mediates isoform-specific activation of p38 and upregulation of collagen gene transcription by a mechanism involving the alpha2 cytoplasmic tail. J Cell Biol 1999, 147:401-416.
-
(1999)
J Cell Biol
, vol.147
, pp. 401-416
-
-
Ivaska, J.1
Reunanen, H.2
Westermarck, J.3
Koivisto, L.4
Kahari, V.M.5
Heino, J.6
-
81
-
-
0028802599
-
The yeast tribrid system - genetic detection of trans-phosphorylated ITAM-SH2-interactions
-
Osborne MA, Dalton S, Kochan JP: The yeast tribrid system - genetic detection of trans-phosphorylated ITAM-SH2-interactions. Biotechnology 1995, 13:1474-1478.
-
(1995)
Biotechnology
, vol.13
, pp. 1474-1478
-
-
Osborne, M.A.1
Dalton, S.2
Kochan, J.P.3
-
82
-
-
0029587597
-
Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase
-
Huang X, Li Y, Tanaka K, Moore KG, Hayashi JI: Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase. Proc Natl Acad Sci USA 1995, 92:11618-11622.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 11618-11622
-
-
Huang, X.1
Li, Y.2
Tanaka, K.3
Moore, K.G.4
Hayashi, J.I.5
-
83
-
-
0030812414
-
Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation
-
Yokouchi M, Suzuki R, Masuhara M, Komiya S, Inoue A, Yoshimura A: Cloning and characterization of APS, an adaptor molecule containing PH and SH2 domains that is tyrosine phosphorylated upon B-cell receptor stimulation. Oncogene 1997, 15:7-15.
-
(1997)
Oncogene
, vol.15
, pp. 7-15
-
-
Yokouchi, M.1
Suzuki, R.2
Masuhara, M.3
Komiya, S.4
Inoue, A.5
Yoshimura, A.6
-
84
-
-
0033637359
-
Control of B cell production by the adaptor protein Ink. Definition of a conserved family of signal-modulating proteins
-
Takaki S, Sauer K, Iritani BM, Chien S, Ebihara Y, Tsuji K, Takatsu K, Perlmutter RM: Control of B cell production by the adaptor protein Ink. Definition of a conserved family of signal-modulating proteins. Immunity 2000, 13:599-609.
-
(2000)
Immunity
, vol.13
, pp. 599-609
-
-
Takaki, S.1
Sauer, K.2
Iritani, B.M.3
Chien, S.4
Ebihara, Y.5
Tsuji, K.6
Takatsu, K.7
Perlmutter, R.M.8
-
85
-
-
0033562558
-
Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes
-
Horrevoets AJ, Fontijn RD, van Zonneveld AJ, de Vries CJ, ten Cate JW, Pannekoek H: Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes. Blood 1999, 93:3418-3431.
-
(1999)
Blood
, vol.93
, pp. 3418-3431
-
-
Horrevoets, A.J.1
Fontijn, R.D.2
Van Zonneveld, A.J.3
De Vries, C.J.4
Ten Cate, J.W.5
Pannekoek, H.6
-
86
-
-
0034723360
-
Identification of a novel tumor necrosis factor-alpha-inducible gene, SCC-S2, containing the consensus sequence of a death effector domain of fas-associated death domain-like interleukin-1 beta-converting enzyme-inhibitory protein
-
Kumar D, Whiteside TL, Kasid U: Identification of a novel tumor necrosis factor-alpha-inducible gene, SCC-S2, containing the consensus sequence of a death effector domain of fas-associated death domain-like interleukin-1 beta-converting enzyme-inhibitory protein. J Biol Chem 2000, 275:2973-2978.
-
(2000)
J Biol Chem
, vol.275
, pp. 2973-2978
-
-
Kumar, D.1
Whiteside, T.L.2
Kasid, U.3
|