-
2
-
-
0028844134
-
Cathelicidins: A novel protein family with a common proregion and a variable C-terminal antimicrobial domain
-
Zanetti M. Gennaro R. Romeo D. Cathelicidins: a novel protein family with a common proregion and a variable C-terminal antimicrobial domain FEBS Lett. 374 1995 1-5
-
(1995)
FEBS Lett.
, vol.374
, pp. 1-5
-
-
Zanetti, M.1
Gennaro, R.2
Romeo, D.3
-
3
-
-
0032319580
-
Human salivary histatins: Promising anti-fungal therapeutic agents
-
Tsai H. Bobek L.A. Human salivary histatins: promising anti-fungal therapeutic agents Crit. Rev. Oral Biol. Med. 9 1998 480-497
-
(1998)
Crit. Rev. Oral Biol. Med.
, vol.9
, pp. 480-497
-
-
Tsai, H.1
Bobek, L.A.2
-
4
-
-
0035198723
-
Dermcidin: A novel human antibiotic peptide secreted by sweat glands
-
Schittek B. Hipfel R. Sauer B. Bauer J. Kalbacher H. Stevanovic S. Schirle M. Schroeder K. Blin N. Meier F. Rassner G. Garbe C. Dermcidin: a novel human antibiotic peptide secreted by sweat glands Nat. Immunol. 2 2001 1133-1137
-
(2001)
Nat. Immunol.
, vol.2
, pp. 1133-1137
-
-
Schittek, B.1
Hipfel, R.2
Sauer, B.3
Bauer, J.4
Kalbacher, H.5
Stevanovic, S.6
Schirle, M.7
Schroeder, K.8
Blin, N.9
Meier, F.10
Rassner, G.11
Garbe, C.12
-
5
-
-
0030845025
-
Small, anionic, and charge-neutralizing propeptide fragments of zymogens are antimicrobial
-
Brogden K.A. Ackermann M. Huttner K.M. Small, anionic, and charge-neutralizing propeptide fragments of zymogens are antimicrobial Antimicrob. Agents Chemother. 41 1997 1615-1617
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1615-1617
-
-
Brogden, K.A.1
Ackermann, M.2
Huttner, K.M.3
-
7
-
-
0032942727
-
In vitro antibacterial properties of pexiganan, an analog of magainin
-
Ge Y. MacDonald D.L. Holroyd K.J. Thornsberry C. Wexler H. Zasloff M. In vitro antibacterial properties of pexiganan, an analog of magainin Antimicrob. Agents Chemother. 43 1999 782-788
-
(1999)
Antimicrob. Agents Chemother.
, vol.43
, pp. 782-788
-
-
Ge, Y.1
MacDonald, D.L.2
Holroyd, K.J.3
Thornsberry, C.4
Wexler, H.5
Zasloff, M.6
-
8
-
-
0030855146
-
Protegrin-1: A broad-spectrum, rapidly microbicidal peptide with in vivo activity
-
Steinberg D.A. Hurst M.A. Fujii C.A. Kung A.H. Ho J.F. Cheng F.C. Loury D.J. Fiddes J.C. Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity Antimicrob. Agents Chemother. 41 1997 1738-1742
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1738-1742
-
-
Steinberg, D.A.1
Hurst, M.A.2
Fujii, C.A.3
Kung, A.H.4
Ho, J.F.5
Cheng, F.C.6
Loury, D.J.7
Fiddes, J.C.8
-
9
-
-
0034116709
-
Evaluation of the inactivation of infectious Herpes simplex virus by host-defense peptides
-
Yasin B. Pang M. Turner J.S. Cho Y. Dinh N.N. Waring A.J. Lehrer R.I. Wagar E.A. Evaluation of the inactivation of infectious Herpes simplex virus by host-defense peptides Eur. J. Clin. Microbiol. Infect. Dis. 19 2000 187-194
-
(2000)
Eur. J. Clin. Microbiol. Infect. Dis.
, vol.19
, pp. 187-194
-
-
Yasin, B.1
Pang, M.2
Turner, J.S.3
Cho, Y.4
Dinh, N.N.5
Waring, A.J.6
Lehrer, R.I.7
Wagar, E.A.8
-
10
-
-
0029616370
-
Magainin-induced cytotoxicity in eukaryotic cells: Kinetics, dose-response and channel characteristics
-
Haimovich B. Tanaka J.C. Magainin-induced cytotoxicity in eukaryotic cells: kinetics, dose-response and channel characteristics Biochim. Biophys. Acta 1240 1995 149-158
-
(1995)
Biochim. Biophys. Acta
, vol.1240
, pp. 149-158
-
-
Haimovich, B.1
Tanaka, J.C.2
-
11
-
-
0021142387
-
Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes
-
Selsted M.E. Szklarek D. Lehrer R.I. Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes Infect. Immun. 45 1984 150-154
-
(1984)
Infect. Immun.
, vol.45
, pp. 150-154
-
-
Selsted, M.E.1
Szklarek, D.2
Lehrer, R.I.3
-
13
-
-
0023945703
-
Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations
-
Lehrer R.I. Ganz T. Szklarek D. Selsted M.E. Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations J. Clin. Invest. 81 1988 1829-1835
-
(1988)
J. Clin. Invest.
, vol.81
, pp. 1829-1835
-
-
Lehrer, R.I.1
Ganz, T.2
Szklarek, D.3
Selsted, M.E.4
-
14
-
-
0022886732
-
In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes
-
Lichtenstein A. Ganz T. Selsted M.E. Lehrer R.I. In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes Blood 68 1986 1407-1410
-
(1986)
Blood
, vol.68
, pp. 1407-1410
-
-
Lichtenstein, A.1
Ganz, T.2
Selsted, M.E.3
Lehrer, R.I.4
-
15
-
-
0023905142
-
Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity
-
Lichtenstein A.K. Ganz T. Nguyen T.M. Selsted M.E. Lehrer R.I. Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity J. Immunol. 140 1988 2686-2694
-
(1988)
J. Immunol.
, vol.140
, pp. 2686-2694
-
-
Lichtenstein, A.K.1
Ganz, T.2
Nguyen, T.M.3
Selsted, M.E.4
Lehrer, R.I.5
-
16
-
-
0025738532
-
Mechanism of mammalian cell lysis mediated by peptide defensins. Evidence for an initial alteration of the plasma membrane
-
Lichtenstein A. Mechanism of mammalian cell lysis mediated by peptide defensins. Evidence for an initial alteration of the plasma membrane J. Clin. Invest. 88 1991 93-100
-
(1991)
J. Clin. Invest.
, vol.88
, pp. 93-100
-
-
Lichtenstein, A.1
-
17
-
-
0021792199
-
Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes
-
Lehrer R.I. Daher K. Ganz T. Selsted M.E. Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes J. Virol. 54 1985 467-472
-
(1985)
J. Virol.
, vol.54
, pp. 467-472
-
-
Lehrer, R.I.1
Daher, K.2
Ganz, T.3
Selsted, M.E.4
-
18
-
-
0022977989
-
Direct inactivation of viruses by human granulocyte defensins
-
Daher K.A. Selsted M.E. Lehrer R.I. Direct inactivation of viruses by human granulocyte defensins J. Virol. 60 1986 1068-1074
-
(1986)
J. Virol.
, vol.60
, pp. 1068-1074
-
-
Daher, K.A.1
Selsted, M.E.2
Lehrer, R.I.3
-
19
-
-
0034713831
-
Action of antimicrobial peptides: Two-state model
-
Huang H.W. Action of antimicrobial peptides: two-state model Biochemistry 39 2000 8347-8352
-
(2000)
Biochemistry
, vol.39
, pp. 8347-8352
-
-
Huang, H.W.1
-
20
-
-
0032717886
-
Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides
-
Shai Y. Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides Biochim. Biophys. Acta 1462 1999 55-70
-
(1999)
Biochim. Biophys. Acta
, vol.1462
, pp. 55-70
-
-
Shai, Y.1
-
21
-
-
0031740520
-
Magainins as paradigm for the mode of action of pore forming polypeptides
-
Matsuzaki K. Magainins as paradigm for the mode of action of pore forming polypeptides Biochim. Biophys. Acta 1376 1998 391-400
-
(1998)
Biochim. Biophys. Acta
, vol.1376
, pp. 391-400
-
-
Matsuzaki, K.1
-
23
-
-
0025021992
-
Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes
-
Kagan B.L. Selsted M.E. Ganz T. Lehrer R.I. Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes Proc. Natl Acad. Sci. USA 87 1990 210-214
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 210-214
-
-
Kagan, B.L.1
Selsted, M.E.2
Ganz, T.3
Lehrer, R.I.4
-
24
-
-
0027218376
-
Defensins promote fusion and lysis of negatively charged membranes
-
Fujii G. Selsted M.E. Eisenberg D. Defensins promote fusion and lysis of negatively charged membranes Protein Sci. 2 1993 1301-1312
-
(1993)
Protein Sci.
, vol.2
, pp. 1301-1312
-
-
Fujii, G.1
Selsted, M.E.2
Eisenberg, D.3
-
25
-
-
0028061984
-
Interactions between human defensins and lipid bilayers: Evidence for formation of multimeric pores
-
Wimley W.C. Selsted M.E. White S.H. Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores Protein Sci. 3 1994 1362-1373
-
(1994)
Protein Sci.
, vol.3
, pp. 1362-1373
-
-
Wimley, W.C.1
Selsted, M.E.2
White, S.H.3
-
26
-
-
0031034840
-
Differential scanning microcalorimetry indicates that human defensin, HNP-2, interacts specifically with biomembrane mimetic systems
-
Lohner K. Latal A. Lehrer R.I. Ganz T. Differential scanning microcalorimetry indicates that human defensin, HNP-2, interacts specifically with biomembrane mimetic systems Biochemistry 36 1997 1525-1531
-
(1997)
Biochemistry
, vol.36
, pp. 1525-1531
-
-
Lohner, K.1
Latal, A.2
Lehrer, R.I.3
Ganz, T.4
-
28
-
-
0025903814
-
Crystal structure of defensin HNP-3, an amphiphilic dimer: Mechanisms of membrane permeabilization
-
Hill C.P. Yee J. Selsted M.E. Eisenberg D. Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization Science 251 1991 1481-1485
-
(1991)
Science
, vol.251
, pp. 1481-1485
-
-
Hill, C.P.1
Yee, J.2
Selsted, M.E.3
Eisenberg, D.4
-
30
-
-
0026468973
-
NMR studies of defensin antimicrobial peptides. 2. Three- dimensional structures of rabbit NP-2 and human HNP-1
-
Pardi A. Zhang X.L. Selsted M.E. Skalicky J.J. Yip P.F. NMR studies of defensin antimicrobial peptides. 2. Three- dimensional structures of rabbit NP-2 and human HNP-1 Biochemistry 31 1992 11357-11364
-
(1992)
Biochemistry
, vol.31
, pp. 11357-11364
-
-
Pardi, A.1
Zhang, X.L.2
Selsted, M.E.3
Skalicky, J.J.4
Yip, P.F.5
-
31
-
-
0026490907
-
NMR studies of defensin antimicrobial peptides. 1. Resonance assignment and secondary structure determination of rabbit NP-2 and human HNP-1
-
Zhang X.L. Selsted M.E. Pardi A. NMR studies of defensin antimicrobial peptides. 1. Resonance assignment and secondary structure determination of rabbit NP-2 and human HNP-1 Biochemistry 31 1992 11348-11356
-
(1992)
Biochemistry
, vol.31
, pp. 11348-11356
-
-
Zhang, X.L.1
Selsted, M.E.2
Pardi, A.3
-
32
-
-
0027981211
-
Structure and dynamics of the neutrophil defensins NP-2, NP-5, and HNP-1: NMR studies of amide hydrogen exchange kinetics
-
Skalicky J.J. Selsted M.E. Pardi A. Structure and dynamics of the neutrophil defensins NP-2, NP-5, and HNP-1: NMR studies of amide hydrogen exchange kinetics Proteins 20 1994 52-67
-
(1994)
Proteins
, vol.20
, pp. 52-67
-
-
Skalicky, J.J.1
Selsted, M.E.2
Pardi, A.3
-
33
-
-
0028825285
-
Solution structure of bovine neutrophil beta-defensin-12: The peptide fold of the beta-defensins is identical to that of the classical defensins
-
Zimmermann G.R. Legault P. Selsted M.E. Pardi A. Solution structure of bovine neutrophil beta-defensin-12: the peptide fold of the beta-defensins is identical to that of the classical defensins Biochemistry 34 1995 13663-13671
-
(1995)
Biochemistry
, vol.34
, pp. 13663-13671
-
-
Zimmermann, G.R.1
Legault, P.2
Selsted, M.E.3
Pardi, A.4
-
35
-
-
0035799314
-
The NMR structure of human beta-defensin-2 reveals a novel alpha- helical segment
-
Sawai M.V. Jia H.P. Liu L. Aseyev V. Wiencek J.M. McCray P.B. Ganz T.Jr. Kearney W.R. Tack B.F. The NMR structure of human beta-defensin-2 reveals a novel alpha- helical segment Biochemistry 40 2001 3810-3816
-
(2001)
Biochemistry
, vol.40
, pp. 3810-3816
-
-
Sawai, M.V.1
Jia, H.P.2
Liu, L.3
Aseyev, V.4
Wiencek, J.M.5
McCray, P.B.6
Ganz Jr., T.7
Kearney, W.R.8
Tack, B.F.9
-
36
-
-
0024511945
-
Determination of the disulfide array in the human defensin HNP-2. A covalently cyclized peptide
-
Selsted M.E. Harwig S.S. Determination of the disulfide array in the human defensin HNP-2. A covalently cyclized peptide J. Biol. Chem. 264 1989 4003-4007
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 4003-4007
-
-
Selsted, M.E.1
Harwig, S.S.2
-
37
-
-
0027414945
-
Characterization of the disulfide motif in BNBD-12, an antimicrobial beta-defensin peptide from bovine neutrophils
-
Tang Y.Q. Selsted M.E. Characterization of the disulfide motif in BNBD-12, an antimicrobial beta-defensin peptide from bovine neutrophils J. Biol. Chem. 268 1993 6649-6653
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 6649-6653
-
-
Tang, Y.Q.1
Selsted, M.E.2
-
38
-
-
0033569410
-
A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins
-
see comments
-
Tang Y.Q. Yuan J. Osapay G. Osapay K. Tran D. Miller C.J. Ouellette A.J. Selsted M.E. A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins Science 286 1999 498-502 see comments
-
(1999)
Science
, vol.286
, pp. 498-502
-
-
Tang, Y.Q.1
Yuan, J.2
Osapay, G.3
Osapay, K.4
Tran, D.5
Miller, C.J.6
Ouellette, A.J.7
Selsted, M.E.8
-
39
-
-
0031213832
-
The human β-defensin-1 and α-defensins are encoded by adjacent genes: Two peptide families with differing disulfide topology share a common ancestry
-
Liu L. Zhao C. Heng H.H.Q. Ganz T. The human β-defensin-1 and α-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry Genomics 43 1997 316-320
-
(1997)
Genomics
, vol.43
, pp. 316-320
-
-
Liu, L.1
Zhao, C.2
Heng, H.H.Q.3
Ganz, T.4
-
40
-
-
0000255408
-
Antibacterial and enzymic basic proteins from leukocyte lysosomes: Separation and identification
-
Zeya H.I. Spitznagel J.K. Antibacterial and enzymic basic proteins from leukocyte lysosomes: separation and identification Science 142 1963 1085-1087
-
(1963)
Science
, vol.142
, pp. 1085-1087
-
-
Zeya, H.I.1
Spitznagel, J.K.2
-
41
-
-
0020562530
-
Antibacterial activity of microbicidal cationic proteins 1 and 2, natural peptide antibiotics of rabbit lung macrophages
-
Lehrer R.I. Selsted M.E. Szklarek D. Fleischmann J. Antibacterial activity of microbicidal cationic proteins 1 and 2, natural peptide antibiotics of rabbit lung macrophages Infect. Immun. 42 1983 10-14
-
(1983)
Infect. Immun.
, vol.42
, pp. 10-14
-
-
Lehrer, R.I.1
Selsted, M.E.2
Szklarek, D.3
Fleischmann, J.4
-
42
-
-
0021032178
-
Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages
-
Selsted M.E. Brown D.M. DeLange R.J. Lehrer R.I. Primary structures of MCP-1 and MCP-2, natural peptide antibiotics of rabbit lung macrophages J. Biol. Chem. 258 1983 14485-14489
-
(1983)
J. Biol. Chem.
, vol.258
, pp. 14485-14489
-
-
Selsted, M.E.1
Brown, D.M.2
DeLange, R.J.3
Lehrer, R.I.4
-
43
-
-
0024521812
-
Developmental regulation of cryptdin, a corticostatin/defensin precursor mRNA in mouse small intestinal crypt epithelium
-
Ouellette A.J. Greco R.M. James M. Frederick D. Naftilan J. Fallon J.T. Developmental regulation of cryptdin, a corticostatin/defensin precursor mRNA in mouse small intestinal crypt epithelium J. Cell Biol. 108 1989 1687-1695
-
(1989)
J. Cell Biol.
, vol.108
, pp. 1687-1695
-
-
Ouellette, A.J.1
Greco, R.M.2
James, M.3
Frederick, D.4
Naftilan, J.5
Fallon, J.T.6
-
44
-
-
0025811874
-
Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: Peptide isolation and cloning of a cDNA
-
Diamond G. Zasloff M. Eck H. Brasseur M. Maloy W.L. Bevins C.L. Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa: peptide isolation and cloning of a cDNA Proc. Natl Acad. Sci. USA 88 1991 3952-3956
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 3952-3956
-
-
Diamond, G.1
Zasloff, M.2
Eck, H.3
Brasseur, M.4
Maloy, W.L.5
Bevins, C.L.6
-
45
-
-
0028211686
-
Gallinacins: Cysteine-rich antimicrobial peptides of chicken leukocytes
-
Harwig S.S. Swiderek K.M. Kokryakov V.N. Tan L. Lee T.D. Panyutich E.A. Aleshina G.M. Shamova O.V. Lehrer R.I. Gallinacins: cysteine-rich antimicrobial peptides of chicken leukocytes FEBS Lett. 342 1994 281-285
-
(1994)
FEBS Lett.
, vol.342
, pp. 281-285
-
-
Harwig, S.S.1
Swiderek, K.M.2
Kokryakov, V.N.3
Tan, L.4
Lee, T.D.5
Panyutich, E.A.6
Aleshina, G.M.7
Shamova, O.V.8
Lehrer, R.I.9
-
46
-
-
0035078646
-
Gallinacin-3, an inducible epithelial beta-defensin in the chicken
-
Zhao C. Nguyen T. Liu L. Sacco R.E. Brogden K.A. Lehrer R.I. Gallinacin-3, an inducible epithelial beta-defensin in the chicken Infect. Immun. 69 2001 2684-2691
-
(2001)
Infect. Immun.
, vol.69
, pp. 2684-2691
-
-
Zhao, C.1
Nguyen, T.2
Liu, L.3
Sacco, R.E.4
Brogden, K.A.5
Lehrer, R.I.6
-
48
-
-
0031694275
-
Characterization of beta-defensin prepropeptide mRNA from chicken and turkey bone marrow
-
Brockus C.W. Jackwood M.W. Harmon B.G. Characterization of beta-defensin prepropeptide mRNA from chicken and turkey bone marrow Anim. Genet. 29 1998 283-289
-
(1998)
Anim. Genet.
, vol.29
, pp. 283-289
-
-
Brockus, C.W.1
Jackwood, M.W.2
Harmon, B.G.3
-
49
-
-
3242776891
-
Snake venom growth arresting peptide
-
Seattle, WA, US Patent No. 4774318-A
-
H. Marquardt, G.J. Todaro, D.R. Twardzik, Snake venom growth arresting peptide, Oncogen, Seattle, WA, US Patent No. 4774318-A 3, 9-27-1988
-
(1988)
Oncogen
, vol.3
, pp. 9-27
-
-
Marquardt, H.1
Todaro, G.J.2
Twardzik, D.R.3
-
50
-
-
0023098960
-
Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes
-
Ganz T. Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes Infect. Immun. 55 1987 568-571
-
(1987)
Infect. Immun.
, vol.55
, pp. 568-571
-
-
Ganz, T.1
-
54
-
-
0033023402
-
Porcine epithelial beta-defensin 1 is expressed in the dorsal tongue at antimicrobial concentrations
-
Shi J. Zhang G. Wu H. Ross C. Blecha F. Ganz T. Porcine epithelial beta-defensin 1 is expressed in the dorsal tongue at antimicrobial concentrations Infect. Immun. 67 1999 3121-3127
-
(1999)
Infect. Immun.
, vol.67
, pp. 3121-3127
-
-
Shi, J.1
Zhang, G.2
Wu, H.3
Ross, C.4
Blecha, F.5
Ganz, T.6
-
57
-
-
0024396994
-
The structure of the rabbit macrophage defensin genes and their organ-specific expression
-
Ganz T. Rayner J.R. Valore E.V. Tumolo A. Talmadge K. Fuller F. The structure of the rabbit macrophage defensin genes and their organ-specific expression J. Immunol. 143 1989 1358-1365
-
(1989)
J. Immunol.
, vol.143
, pp. 1358-1365
-
-
Ganz, T.1
Rayner, J.R.2
Valore, E.V.3
Tumolo, A.4
Talmadge, K.5
Fuller, F.6
-
58
-
-
0031882530
-
Expression of beta-defensin genes in bovine alveolar macrophages
-
Ryan L.K. Rhodes J. Bhat M. Diamond G. Expression of beta-defensin genes in bovine alveolar macrophages Infect. Immun. 66 1998 878-881
-
(1998)
Infect. Immun.
, vol.66
, pp. 878-881
-
-
Ryan, L.K.1
Rhodes, J.2
Bhat, M.3
Diamond, G.4
-
59
-
-
0034806603
-
Inhibition of hBD-3, but not hBD-1 and hBD-2, mRNA expression by corticosteroids
-
Duits L.A. Rademaker M. Ravensbergen B. van Sterkenburg M.A. van Strijen E. Hiemstra P.S. Nibbering P.H. Inhibition of hBD-3, but not hBD-1 and hBD-2, mRNA expression by corticosteroids Biochem. Biophys. Res. Commun. 280 2001 522-525
-
(2001)
Biochem. Biophys. Res. Commun.
, vol.280
, pp. 522-525
-
-
Duits, L.A.1
Rademaker, M.2
Ravensbergen, B.3
van Sterkenburg, M.A.4
van Strijen, E.5
Hiemstra, P.S.6
Nibbering, P.H.7
-
60
-
-
0034332193
-
The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations
-
Agerberth B. Charo J. Werr J. Olsson B. Idali F. Lindbom L. Kiessling R. Jornvall H. Wigzell H. Gudmundsson G.H. The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations Blood 96 2000 3086-3093
-
(2000)
Blood
, vol.96
, pp. 3086-3093
-
-
Agerberth, B.1
Charo, J.2
Werr, J.3
Olsson, B.4
Idali, F.5
Lindbom, L.6
Kiessling, R.7
Jornvall, H.8
Wigzell, H.9
Gudmundsson, G.H.10
-
62
-
-
0025096413
-
Characterization of defensin resistance phenotypes associated with mutations in the phoP virulence regulon of Salmonella typhimurium
-
Miller S.I. Pulkkinen W.S. Selsted M.E. Mekalanos J.J. Characterization of defensin resistance phenotypes associated with mutations in the phoP virulence regulon of Salmonella typhimurium Infect. Immun. 58 1990 3706-3710
-
(1990)
Infect. Immun.
, vol.58
, pp. 3706-3710
-
-
Miller, S.I.1
Pulkkinen, W.S.2
Selsted, M.E.3
Mekalanos, J.J.4
-
63
-
-
0025733456
-
PhoP/PhoQ: Macrophage-specific modulators of Salmonella virulence?
-
Miller S.I. PhoP/PhoQ: macrophage-specific modulators of Salmonella virulence? Mol. Microbiol. 5 1991 2073-2078
-
(1991)
Mol. Microbiol.
, vol.5
, pp. 2073-2078
-
-
Miller, S.I.1
-
64
-
-
0026584772
-
Molecular genetic analysis of the Escherichia coli phoP locus
-
Groisman E.A. Heffron F. Solomon F. Molecular genetic analysis of the Escherichia coli phoP locus J. Bacteriol. 174 1992 486-491
-
(1992)
J. Bacteriol.
, vol.174
, pp. 486-491
-
-
Groisman, E.A.1
Heffron, F.2
Solomon, F.3
-
66
-
-
0033919460
-
A PhoP-regulated outer membrane protease of Salmonella enterica serovar typhimurium promotes resistance to alpha-helical antimicrobial peptides
-
Guina T. Yi E.C. Wang H. Hackett M. Miller S.I. A PhoP-regulated outer membrane protease of Salmonella enterica serovar typhimurium promotes resistance to alpha-helical antimicrobial peptides J. Bacteriol. 182 2000 4077-4086
-
(2000)
J. Bacteriol.
, vol.182
, pp. 4077-4086
-
-
Guina, T.1
Yi, E.C.2
Wang, H.3
Hackett, M.4
Miller, S.I.5
-
67
-
-
0032539553
-
Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family
-
Shafer W.M. Qu X. Waring A.J. Lehrer R.I. Modulation of Neisseria gonorrhoeae susceptibility to vertebrate antibacterial peptides due to a member of the resistance/nodulation/division efflux pump family Proc. Natl Acad. Sci. USA 95 1998 1829-1833
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 1829-1833
-
-
Shafer, W.M.1
Qu, X.2
Waring, A.J.3
Lehrer, R.I.4
-
68
-
-
0033605557
-
Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides
-
Peschel A. Otto M. Jack R.W. Kalbacher H. Jung G. Gotz F. Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides J. Biol. Chem. 274 1999 8405-8410
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8405-8410
-
-
Peschel, A.1
Otto, M.2
Jack, R.W.3
Kalbacher, H.4
Jung, G.5
Gotz, F.6
-
69
-
-
0035821289
-
Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine
-
Peschel A. Jack R.W. Otto M. Collins L.V. Staubitz P. Nicholson G. Kalbacher H. Nieuwenhuizen W.F. Jung G. Tarkowski A. van Kessel K.P. van Strijp J.A. Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine J. Exp. Med. 193 2001 1067-1076
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1067-1076
-
-
Peschel, A.1
Jack, R.W.2
Otto, M.3
Collins, L.V.4
Staubitz, P.5
Nicholson, G.6
Kalbacher, H.7
Nieuwenhuizen, W.F.8
Jung, G.9
Tarkowski, A.10
van Kessel, K.P.11
van Strijp, J.A.12
-
70
-
-
0024797674
-
Monocyte-chemotactic activity of defensins from human neutrophils
-
Territo M.C. Ganz T. Selsted M.E. Lehrer R. Monocyte-chemotactic activity of defensins from human neutrophils J. Clin. Invest. 84 1989 2017-2020
-
(1989)
J. Clin. Invest.
, vol.84
, pp. 2017-2020
-
-
Territo, M.C.1
Ganz, T.2
Selsted, M.E.3
Lehrer, R.4
-
71
-
-
0030038197
-
Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8- stimulated neutrophils
-
Chertov O. Michiel D.F. Xu L. Wang J.M. Tani K. Murphy W.J. Longo D.L. Taub D.D. Oppenheim J.J. Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8- stimulated neutrophils J. Biol. Chem. 271 1996 2935-2940
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2935-2940
-
-
Chertov, O.1
Michiel, D.F.2
Xu, L.3
Wang, J.M.4
Tani, K.5
Murphy, W.J.6
Longo, D.L.7
Taub, D.D.8
Oppenheim, J.J.9
-
72
-
-
0033569408
-
Beta-defensins: Linking innate and adaptive immunity through dendritic and T cell CCR6
-
see comments
-
Yang D. Chertov O. Bykovskaia S.N. Chen Q. Buffo M.J. Shogan J. Anderson M. Schroder J.M. Wang J.M. Howard O.M. Oppenheim J.J. Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6 Science 286 1999 525-528 see comments
-
(1999)
Science
, vol.286
, pp. 525-528
-
-
Yang, D.1
Chertov, O.2
Bykovskaia, S.N.3
Chen, Q.4
Buffo, M.J.5
Shogan, J.6
Anderson, M.7
Schroder, J.M.8
Wang, J.M.9
Howard, O.M.10
Oppenheim, J.J.11
-
73
-
-
0033844287
-
Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells
-
Yang D. Chen Q. Chertov O. Oppenheim J.J. Human neutrophil defensins selectively chemoattract naive T and immature dendritic cells J. Leukoc. Biol. 68 2000 9-14
-
(2000)
J. Leukoc. Biol.
, vol.68
, pp. 9-14
-
-
Yang, D.1
Chen, Q.2
Chertov, O.3
Oppenheim, J.J.4
-
74
-
-
0023636937
-
The corticostatic (anti-ACTH) and cytotoxic activity of peptides isolated from fetal, adult and tumor-bearing lung
-
Zhu Q.Z. Singh A.V. Bateman A. Esch F. Solomon S. The corticostatic (anti-ACTH) and cytotoxic activity of peptides isolated from fetal, adult and tumor-bearing lung J. Steroid. Biochem. 27 1987 1017-1022
-
(1987)
J. Steroid. Biochem.
, vol.27
, pp. 1017-1022
-
-
Zhu, Q.Z.1
Singh, A.V.2
Bateman, A.3
Esch, F.4
Solomon, S.5
-
75
-
-
0024381745
-
Isolation and biological activity of corticostatic peptides (anti-ACTH)
-
Zhu Q. Bateman A. Singh A. Solomon S. Isolation and biological activity of corticostatic peptides (anti-ACTH) Endocr. Res. 15 1989 129-149
-
(1989)
Endocr. Res.
, vol.15
, pp. 129-149
-
-
Zhu, Q.1
Bateman, A.2
Singh, A.3
Solomon, S.4
-
79
-
-
15844422471
-
The isolation and characterization of a novel corticostatin/defensin-like peptide from the kidney
-
Bateman A. MacLeod R.J. Lembessis P. Hu J. Esch F. Solomon S. The isolation and characterization of a novel corticostatin/defensin-like peptide from the kidney J. Biol. Chem. 271 1996 10654-10659
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10654-10659
-
-
Bateman, A.1
MacLeod, R.J.2
Lembessis, P.3
Hu, J.4
Esch, F.5
Solomon, S.6
-
81
-
-
0035000423
-
Cryptdin-3 induces novel apical conductance(s) in Cl-secretory, including cystic fibrosis, epithelia
-
D. Merlin, G. Yue, W.L. Lencer, M.E. Selsted, J.L. Madara, Cryptdin-3 induces novel apical conductance(s) in Cl-secretory, including cystic fibrosis, epithelia Am. J. Physiol. Cell Physiol. 280 2001 C296-C302
-
(2001)
Am. J. Physiol. Cell Physiol.
, vol.280
-
-
Merlin, D.1
Yue, G.2
Lencer, W.L.3
Selsted, M.E.4
Madara, J.L.5
-
82
-
-
0342804468
-
Multiple promoter and splicing mRNA variants of the epididymis-specific gene EP2
-
Frohlich O. Po C. Murphy T. Young L.G. Multiple promoter and splicing mRNA variants of the epididymis-specific gene EP2 J. Androl. 21 2000 421-430
-
(2000)
J. Androl.
, vol.21
, pp. 421-430
-
-
Frohlich, O.1
Po, C.2
Murphy, T.3
Young, L.G.4
-
83
-
-
0035793879
-
An antimicrobial peptide gene found in the male reproductive system of rats
-
Li P. Chan H.C. He B. So S.C. Chung Y.W. Shang Q. Zhang Y.D. Zhang Y.L. An antimicrobial peptide gene found in the male reproductive system of rats Science 291 2001 1783-1785
-
(2001)
Science
, vol.291
, pp. 1783-1785
-
-
Li, P.1
Chan, H.C.2
He, B.3
So, S.C.4
Chung, Y.W.5
Shang, Q.6
Zhang, Y.D.7
Zhang, Y.L.8
-
84
-
-
0037235102
-
Expression of antimicrobial defensins in the male reproductive tract of rats, mice, and humans
-
Com E. Bourgeon F. Evrard B. Ganz T. Colleu D. Jegou B. Pineau C. Expression of antimicrobial defensins in the male reproductive tract of rats, mice, and humans Biol. Reprod. 68 2003 95-104
-
(2003)
Biol. Reprod.
, vol.68
, pp. 95-104
-
-
Com, E.1
Bourgeon, F.2
Evrard, B.3
Ganz, T.4
Colleu, D.5
Jegou, B.6
Pineau, C.7
-
85
-
-
0024708162
-
Assignment of defensin gene(s) to human chromosome 8p23
-
R.S. Sparkes, M. Kronenberg, C. Heinzmann, K.A. Daher, I. Klisak, T. Ganz, T. Mohandas, Assignment of defensin gene(s) to human chromosome 8p23 Genomics 5 1989 240-244
-
(1989)
Genomics
, vol.5
, pp. 240-244
-
-
Sparkes, R.S.1
Kronenberg, M.2
Heinzmann, C.3
Daher, K.A.4
Klisak, I.5
Ganz, T.6
Mohandas, T.7
-
87
-
-
0032548181
-
Structure and mapping of the human β-defensin HBD-2 gene and its expression at sites of inflammation
-
Liu L. Wang L. Jia H.P. Zhao C. Heng H.H.Q. Schutte B.C. McCray P.B.J. Ganz T. Structure and mapping of the human β-defensin HBD-2 gene and its expression at sites of inflammation Gene 222 1998 237-244
-
(1998)
Gene
, vol.222
, pp. 237-244
-
-
Liu, L.1
Wang, L.2
Jia, H.P.3
Zhao, C.4
Heng, H.H.Q.5
Schutte, B.C.6
McCray, P.B.J.7
Ganz, T.8
-
88
-
-
0032815762
-
A 450-kb contig of defensin genes on human chromosome 8p23
-
Linzmeier R. Ho C.H. Hoang B.V. Ganz T. A 450-kb contig of defensin genes on human chromosome 8p23 Gene 233 1999 205-211
-
(1999)
Gene
, vol.233
, pp. 205-211
-
-
Linzmeier, R.1
Ho, C.H.2
Hoang, B.V.3
Ganz, T.4
-
89
-
-
0037133295
-
Discovery of five conserved beta-defensin gene clusters using a computational search strategy
-
Schutte B.C. Mitros J.P. Bartlett J.A. Walters J.D. Jia H.P. Welsh M.J. Casavant T.L. McCray Jr. P.B. Discovery of five conserved beta-defensin gene clusters using a computational search strategy Proc. Natl Acad. Sci. USA 99 2002 2129-2133
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 2129-2133
-
-
Schutte, B.C.1
Mitros, J.P.2
Bartlett, J.A.3
Walters, J.D.4
Jia, H.P.5
Welsh, M.J.6
Casavant, T.L.7
McCray Jr., P.B.8
-
90
-
-
0029616710
-
Inheritance of unequal numbers of the genes encoding the human neutrophil defensins HP-1 and HP-3
-
Mars W.M. Patmasiriwat P. Maity T. Huff V. Weil M.M. Saunders G.F. Inheritance of unequal numbers of the genes encoding the human neutrophil defensins HP-1 and HP-3 J. Biol. Chem. 270 1995 30371-30376
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 30371-30376
-
-
Mars, W.M.1
Patmasiriwat, P.2
Maity, T.3
Huff, V.4
Weil, M.M.5
Saunders, G.F.6
-
91
-
-
0042387792
-
Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster
-
Hollox E.J. Armour J.A. Barber J.C. Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster Am. J. Hum. Genet. 73 2003 591-600
-
(2003)
Am. J. Hum. Genet.
, vol.73
, pp. 591-600
-
-
Hollox, E.J.1
Armour, J.A.2
Barber, J.C.3
-
93
-
-
0026652575
-
Cationic defensins arise from charge-neutralized propeptides: A mechanism for avoiding leukocyte autocytotoxicity?
-
Michaelson D. Rayner J. Couto M. Ganz T. Cationic defensins arise from charge-neutralized propeptides: a mechanism for avoiding leukocyte autocytotoxicity? J. Leukoc. Biol. 51 1992 634-639
-
(1992)
J. Leukoc. Biol.
, vol.51
, pp. 634-639
-
-
Michaelson, D.1
Rayner, J.2
Couto, M.3
Ganz, T.4
-
94
-
-
0029978338
-
Intramolecular inhibition of human defensin HNP-1 by its propiece
-
Valore E.V. Martin E. Harwig S.S. Ganz T. Intramolecular inhibition of human defensin HNP-1 by its propiece J. Clin. Invest. 97 1996 1624-1629
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 1624-1629
-
-
Valore, E.V.1
Martin, E.2
Harwig, S.S.3
Ganz, T.4
-
95
-
-
0028898423
-
The pro region of human neutrophil defensin contains a motif that is essential for normal subcellular sorting
-
Liu L. Ganz T. The pro region of human neutrophil defensin contains a motif that is essential for normal subcellular sorting Blood 85 1995 1095-1103
-
(1995)
Blood
, vol.85
, pp. 1095-1103
-
-
Liu, L.1
Ganz, T.2
-
97
-
-
0031756983
-
Timing, targeting and sorting of azurophil granule proteins in human myeloid cells
-
Arnljots K. Sorensen O. Lollike K. Borregaard N. Timing, targeting and sorting of azurophil granule proteins in human myeloid cells Leukemia 12 1998 1789-1795
-
(1998)
Leukemia
, vol.12
, pp. 1789-1795
-
-
Arnljots, K.1
Sorensen, O.2
Lollike, K.3
Borregaard, N.4
-
98
-
-
0033405818
-
The individual regulation of granule protein mRNA levels during neutrophil maturation explains the heterogeneity of neutrophil granules
-
Cowland J.B. Borregaard N. The individual regulation of granule protein mRNA levels during neutrophil maturation explains the heterogeneity of neutrophil granules J. Leukoc. Biol. 66 1999 989-995
-
(1999)
J. Leukoc. Biol.
, vol.66
, pp. 989-995
-
-
Cowland, J.B.1
Borregaard, N.2
-
99
-
-
0026535104
-
Posttranslational processing of defensins in immature human myeloid cells
-
Valore E.V. Ganz T. Posttranslational processing of defensins in immature human myeloid cells Blood 79 1992 1538-1544
-
(1992)
Blood
, vol.79
, pp. 1538-1544
-
-
Valore, E.V.1
Ganz, T.2
-
100
-
-
0026609053
-
Characterization of defensin precursors in mature human neutrophils
-
Harwig S.S. Park A.S. Lehrer R.I. Characterization of defensin precursors in mature human neutrophils Blood 79 1992 1532-1537
-
(1992)
Blood
, vol.79
, pp. 1532-1537
-
-
Harwig, S.S.1
Park, A.S.2
Lehrer, R.I.3
-
101
-
-
0028832566
-
Differences in the interaction of heparin with arginine and lysine and the importance of these basic amino acids in the binding of heparin to acidic fibroblast growth factor
-
Fromm J.R. Hileman R.E. Caldwell E.E. Weiler J.M. Linhardt R.J. Differences in the interaction of heparin with arginine and lysine and the importance of these basic amino acids in the binding of heparin to acidic fibroblast growth factor Arch. Biochem. Biophys. 323 1995 279-287
-
(1995)
Arch. Biochem. Biophys.
, vol.323
, pp. 279-287
-
-
Fromm, J.R.1
Hileman, R.E.2
Caldwell, E.E.3
Weiler, J.M.4
Linhardt, R.J.5
-
102
-
-
0032006909
-
Glycosaminoglycan-protein interactions: Definition of consensus sites in glycosaminoglycan binding proteins
-
Hileman R.E. Fromm J.R. Weiler J.M. Linhardt R.J. Glycosaminoglycan-protein interactions: definition of consensus sites in glycosaminoglycan binding proteins Bioessays 20 1998 156-167
-
(1998)
Bioessays
, vol.20
, pp. 156-167
-
-
Hileman, R.E.1
Fromm, J.R.2
Weiler, J.M.3
Linhardt, R.J.4
-
103
-
-
0033214433
-
Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense
-
Wilson C.L. Ouellette A.J. Satchell D.P. Ayabe T. Lopez-Boado Y.S. Stratman J.L. Hultgren S.J. Matrisian L.M. Parks W.C. Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense Science 286 1999 113-117
-
(1999)
Science
, vol.286
, pp. 113-117
-
-
Wilson, C.L.1
Ouellette, A.J.2
Satchell, D.P.3
Ayabe, T.4
Lopez-Boado, Y.S.5
Stratman, J.L.6
Hultgren, S.J.7
Matrisian, L.M.8
Parks, W.C.9
-
104
-
-
0037417311
-
Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin
-
Salzman N.H. Ghosh D. Huttner K.M. Paterson Y. Bevins C.L. Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin Nature 422 2003 522-526
-
(2003)
Nature
, vol.422
, pp. 522-526
-
-
Salzman, N.H.1
Ghosh, D.2
Huttner, K.M.3
Paterson, Y.4
Bevins, C.L.5
-
105
-
-
0036259887
-
Characterization of the mouse beta defensin 1, Defb1, mutant mouse model
-
Morrison G. Kilanowski F. Davidson D. Dorin J. Characterization of the mouse beta defensin 1, Defb1, mutant mouse model Infect. Immun. 70 2002 3053-3060
-
(2002)
Infect. Immun.
, vol.70
, pp. 3053-3060
-
-
Morrison, G.1
Kilanowski, F.2
Davidson, D.3
Dorin, J.4
-
107
-
-
0035936156
-
Innate antimicrobial peptide protects the skin from invasive bacterial infection
-
Nizet V. Ohtake T. Lauth X. Trowbridge J. Rudisill J. Dorschner R.A. Pestonjamasp V. Piraino J. Huttner K. Gallo R.L. Innate antimicrobial peptide protects the skin from invasive bacterial infection Nature 414 2001 454-457
-
(2001)
Nature
, vol.414
, pp. 454-457
-
-
Nizet, V.1
Ohtake, T.2
Lauth, X.3
Trowbridge, J.4
Rudisill, J.5
Dorschner, R.A.6
Pestonjamasp, V.7
Piraino, J.8
Huttner, K.9
Gallo, R.L.10
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