-
1
-
-
1542377424
-
A Toll-like receptor that prevents infection by uropathogenic bacteria
-
Zhang, D., G. Zhang, M. S. Hayden, M. B. Greenblatt, C. Bussey, R. A. Flavell, and S. Ghosh. 2004. A Toll-like receptor that prevents infection by uropathogenic bacteria. Science 303:1522.
-
(2004)
Science
, vol.303
, pp. 1522
-
-
Zhang, D.1
Zhang, G.2
Hayden, M.S.3
Greenblatt, M.B.4
Bussey, C.5
Flavell, R.A.6
Ghosh, S.7
-
2
-
-
0033844166
-
Toll-like receptors: A growing family of immune receptors that are differentially expressed and regulated by different leukocytes
-
Muzio, M., N. Polentarutti, D. Bosisio, M. K. Prahladan, and A. Mantovani. 2000. Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes. J. Leukocyte Biol. 67:450.
-
(2000)
J. Leukocyte Biol.
, vol.67
, pp. 450
-
-
Muzio, M.1
Polentarutti, N.2
Bosisio, D.3
Prahladan, M.K.4
Mantovani, A.5
-
3
-
-
0031905311
-
A family of human receptors structurally related to Drosophila Toll
-
Rock, F. L., G. Hardiman, J. C. Timans, R. A. Kastelein, and J. F. Bazan. 1998. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. USA 95:588.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 588
-
-
Rock, F.L.1
Hardiman, G.2
Timans, J.C.3
Kastelein, R.A.4
Bazan, J.F.5
-
4
-
-
0033614428
-
TLR6: A novel member of an expanding Toll-like receptor family
-
Takeuchi, O., T. Kawai, H. Sanjo, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, K. Takeda, and S. Akira. 1999. TLR6: a novel member of an expanding Toll-like receptor family. Gene 231:59.
-
(1999)
Gene
, vol.231
, pp. 59
-
-
Takeuchi, O.1
Kawai, T.2
Sanjo, H.3
Copeland, N.G.4
Gilbert, D.J.5
Jenkins, N.A.6
Takeda, K.7
Akira, S.8
-
5
-
-
0033574415
-
Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction
-
Chow, J. C., D. W. Young, D. T. Golenbock, W. J. Christ, and F. Gusovsky. 1999. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J. Biol. Chem. 274:10689.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10689
-
-
Chow, J.C.1
Young, D.W.2
Golenbock, D.T.3
Christ, W.J.4
Gusovsky, F.5
-
6
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
-
Shimazu, R., S. Akashi, H. Ogata, Y. Nagai, K. Fukudome, K. Miyake, and M. Kimoto. 1999. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189:1777.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1777
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
Nagai, Y.4
Fukudome, K.5
Miyake, K.6
Kimoto, M.7
-
7
-
-
0033213590
-
Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
-
Takeuchi, O., K. Hoshino, T. Kawai, H. Sanjo, H. Takada, T. Ogawa, K. Takeda, and S. Akira. 1999. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11:443.
-
(1999)
Immunity
, vol.11
, pp. 443
-
-
Takeuchi, O.1
Hoshino, K.2
Kawai, T.3
Sanjo, H.4
Takada, H.5
Ogawa, T.6
Takeda, K.7
Akira, S.8
-
8
-
-
0033580949
-
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2
-
Schwandner, R., R. Dziarski, H. Wesche, M. Rothe, and C. J. Kirschning. 1999. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by Toll-like receptor 2. J. Biol. Chem. 274:17406.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17406
-
-
Schwandner, R.1
Dziarski, R.2
Wesche, H.3
Rothe, M.4
Kirschning, C.J.5
-
9
-
-
0033592748
-
The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
-
Underbill, D. M., A. Ozinsky, A. M. Hajjar, A. Stevens, C. B. Wilson, M. Bassetti, and A. Aderem. 1999. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 401:811.
-
(1999)
Nature
, vol.401
, pp. 811
-
-
Underbill, D.M.1
Ozinsky, A.2
Hajjar, A.M.3
Stevens, A.4
Wilson, C.B.5
Bassetti, M.6
Aderem, A.7
-
10
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi, F., K. D. Smith, A. Ozinsky, T. R. Hawn, E. C. Yi, D. R. Goodlett, J. K. Eng, S. Akira, D. M. Underbill, and A. Aderem. 2001. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410:1099.
-
(2001)
Nature
, vol.410
, pp. 1099
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
Eng, J.K.7
Akira, S.8
Underbill, D.M.9
Aderem, A.10
-
11
-
-
0037177833
-
HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway
-
Vabulas, R. M., P. Ahmad-Nejad, S. Ghose, C. J. Kirschning, R. D. Issels, and H. Wagner. 2002. HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway. J. Biol. Chem. 277:15107.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15107
-
-
Vabulas, R.M.1
Ahmad-Nejad, P.2
Ghose, S.3
Kirschning, C.J.4
Issels, R.D.5
Wagner, H.6
-
12
-
-
0034650427
-
Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the Toll-like receptor-4 complex
-
Ohashi, K., V. Burkart, S. Flohe, and H. Kolb. 2000. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the Toll-like receptor-4 complex. J. Immunol. 164:558.
-
(2000)
J. Immunol.
, vol.164
, pp. 558
-
-
Ohashi, K.1
Burkart, V.2
Flohe, S.3
Kolb, H.4
-
13
-
-
0034610291
-
The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors
-
Ozinsky, A., D. M. Underhill, J. D. Fontenot, A. M. Hajjar, K. D. Smith, C. B. Wilson, L. Schroeder, and A. Aderem. 2000. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors. Proc. Natl. Acad. Sci. USA 97:13766.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 13766
-
-
Ozinsky, A.1
Underhill, D.M.2
Fontenot, J.D.3
Hajjar, A.M.4
Smith, K.D.5
Wilson, C.B.6
Schroeder, L.7
Aderem, A.8
-
14
-
-
0035165287
-
Cutting edge: Functional interactions between Toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin
-
Hajjar, A. M., D. S. O'Mahony, A. Ozinsky, D. M. Underhill, A. Aderem, S. J. Klebanoff, and C. B. Wilson. 2001. Cutting edge: functional interactions between Toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin. J. Immunol 166:15.
-
(2001)
J. Immunol.
, vol.166
, pp. 15
-
-
Hajjar, A.M.1
O'Mahony, D.S.2
Ozinsky, A.3
Underhill, D.M.4
Aderem, A.5
Klebanoff, S.J.6
Wilson, C.B.7
-
15
-
-
0036344106
-
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
-
Alexopoulou, L., V. Thomas, M. Schnare, Y. Lobet, J. Anguita, R. T. Schoen, R. Medzhitov, E. Fikrig, and R. A. Flavell. 2002. Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. Nat. Med 8:878.
-
(2002)
Nat. Med.
, vol.8
, pp. 878
-
-
Alexopoulou, L.1
Thomas, V.2
Schnare, M.3
Lobet, Y.4
Anguita, J.5
Schoen, R.T.6
Medzhitov, R.7
Fikrig, E.8
Flavell, R.A.9
-
16
-
-
0035339861
-
Endotoxin-induced maturation of MyD88-deficient dendritic cells
-
Kaisho, T., O. Takeuchi, T. Kawai, K. Hoshino, and S. Akira. 2001. Endotoxin-induced maturation of MyD88-deficient dendritic cells. J. Immunol. 166:5688.
-
(2001)
J. Immunol.
, vol.166
, pp. 5688
-
-
Kaisho, T.1
Takeuchi, O.2
Kawai, T.3
Hoshino, K.4
Akira, S.5
-
17
-
-
0033166472
-
Unresponsiveness of MyD88-deficient mice to endotoxin
-
Kawai, T., O. Adachi, T. Ogawa, K. Takeda, and S. Akira. 1999. Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11:115.
-
(1999)
Immunity
, vol.11
, pp. 115
-
-
Kawai, T.1
Adachi, O.2
Ogawa, T.3
Takeda, K.4
Akira, S.5
-
18
-
-
0031423761
-
MyD88: An adapter that recruits IRAK to the IL-1 receptor complex
-
Wesche, H., W. J. Henzel, W. Shillinglaw, S. Li, and Z. Cao. 1997. MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. Immunity 7:837.
-
(1997)
Immunity
, vol.7
, pp. 837
-
-
Wesche, H.1
Henzel, W.J.2
Shillinglaw, W.3
Li, S.4
Cao, Z.5
-
19
-
-
0030694108
-
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling
-
Muzio, M., J. Ni, P. Feng, and V. M. Dixit. 1997. IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. Science 278:1612.
-
(1997)
Science
, vol.278
, pp. 1612
-
-
Muzio, M.1
Ni, J.2
Feng, P.3
Dixit, V.M.4
-
20
-
-
0035084913
-
Micrococci and peptidoglycan activate TLR2→MyD88→IRAK→ TRAF→NIK→IKK→ NF-κB signal transduction pathway that induces transcription of interleukin-8
-
Wang, Q., R. Dziarski, C. J. Kirschning, M. Muzio, and D. Gupta. 2001. Micrococci and peptidoglycan activate TLR2→MyD88→IRAK→TRAF→ NIK→IKK→ NF-κB signal transduction pathway that induces transcription of interleukin-8. Infect. Immun. 69:2270.
-
(2001)
Infect. Immun.
, vol.69
, pp. 2270
-
-
Wang, Q.1
Dziarski, R.2
Kirschning, C.J.3
Muzio, M.4
Gupta, D.5
-
21
-
-
0029836383
-
Differential activation of extracellular signal-regulated kinase (ERK) 1, ERK2, p38, and c-Jun NH2-terminal kinase mitogen-activated protein kinases by bacterial peptidoglycan
-
Dziarski, R., Y. P. Jin, and D. Gupta. 1996. Differential activation of extracellular signal-regulated kinase (ERK) 1, ERK2, p38, and c-Jun NH2-terminal kinase mitogen-activated protein kinases by bacterial peptidoglycan. J. Infect. Dis. 174:777.
-
(1996)
J. Infect. Dis.
, vol.174
, pp. 777
-
-
Dziarski, R.1
Jin, Y.P.2
Gupta, D.3
-
22
-
-
0035469890
-
Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation and Egr-1 expression
-
Guha, M., M. A. O'Connell, R. Pawlinski, A. Hollis, P. McGovern, S. F. Yan, D. Stern, and N. Mackman. 2001. Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation and Egr-1 expression. Blood 98:1429.
-
(2001)
Blood
, vol.98
, pp. 1429
-
-
Guha, M.1
O'Connell, M.A.2
Pawlinski, R.3
Hollis, A.4
McGovern, P.5
Yan, S.F.6
Stern, D.7
Mackman, N.8
-
23
-
-
0033583034
-
Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes
-
Zhang, F. X., C. J. Kirschning, R. Mancinelli, X. P. Xu, Y. Jin, E. Faure, A. Mantovani, M. Rothe, M. Muzio, and M. Arditi. 1999. Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J. Biol. Chem. 274:7611.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7611
-
-
Zhang, F.X.1
Kirschning, C.J.2
Mancinelli, R.3
Xu, X.P.4
Jin, Y.5
Faure, E.6
Mantovani, A.7
Rothe, M.8
Muzio, M.9
Arditi, M.10
-
24
-
-
0013965646
-
Mechanisms of endotoxin tolerance. IV. Specificity of the pyrogenic refractory state during continuous intravenous infusions of endotoxin
-
Greisman, S. E., E. J. Young, and W. E. Woodward. 1966. Mechanisms of endotoxin tolerance. IV. Specificity of the pyrogenic refractory state during continuous intravenous infusions of endotoxin. J. Exp. Med. 124:983.
-
(1966)
J. Exp. Med.
, vol.124
, pp. 983
-
-
Greisman, S.E.1
Young, E.J.2
Woodward, W.E.3
-
25
-
-
0037183979
-
Induction of bacterial lipoprotein tolerance is associated with suppression of Toll-like receptor 2 expression
-
Wang, J. H., M. Doyle, B. J. Manning, Q. D. Wu, S. Blankson, and H. P. Redmond. 2002. Induction of bacterial lipoprotein tolerance is associated with suppression of Toll-like receptor 2 expression. J. Biol. Chem. 277:36068.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36068
-
-
Wang, J.H.1
Doyle, M.2
Manning, B.J.3
Wu, Q.D.4
Blankson, S.5
Redmond, H.P.6
-
26
-
-
20244384395
-
Cutting edge: Endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression
-
Nomura, F., S. Akashi, Y. Sakao, S. Sato, T. Kawai, M. Matsumoto, K. Nakanishi, M. Kimoto, K. Miyake, K. Takeda, and S. Akira. 2000. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface Toll-like receptor 4 expression. J. Immunol. 164:3476.
-
(2000)
J. Immunol.
, vol.164
, pp. 3476
-
-
Nomura, F.1
Akashi, S.2
Sakao, Y.3
Sato, S.4
Kawai, T.5
Matsumoto, M.6
Nakanishi, K.7
Kimoto, M.8
Miyake, K.9
Takeda, K.10
Akira, S.11
-
27
-
-
0034725584
-
Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells
-
Li, L., S. Cousart, J. Hu, and C. E. McCall. 2000. Characterization of interleukin-1 receptor-associated kinase in normal and endotoxin-tolerant cells. J. Biol. Chem. 275:23340.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23340
-
-
Li, L.1
Cousart, S.2
Hu, J.3
McCall, C.E.4
-
28
-
-
0037151080
-
Gram-negative flagellin-induced self-tolerance is associated with a block in IRAK release from TLR5
-
Mizel, S. B., and J. A. Snipes. 2002. Gram-negative flagellin-induced self-tolerance is associated with a block in IRAK release from TLR5. J. Biol. Chem. 177:22414.
-
(2002)
J. Biol. Chem.
, vol.177
, pp. 22414
-
-
Mizel, S.B.1
Snipes, J.A.2
-
29
-
-
0036319517
-
A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways
-
Sato, S., O. Takeuchi, T. Fujita, H. Tomizawa, K. Takeda, and S. Akira. 2002. A variety of microbial components induce tolerance to lipopolysaccharide by differentially affecting MyD88-dependent and -independent pathways. Int. Immunol. 14:783.
-
(2002)
Int. Immunol.
, vol.14
, pp. 783
-
-
Sato, S.1
Takeuchi, O.2
Fujita, T.3
Tomizawa, H.4
Takeda, K.5
Akira, S.6
-
30
-
-
0026582215
-
Anti-endotoxin monoclonal antibodies: A second look
-
Wenzel, R. P. 1992. Anti-endotoxin monoclonal antibodies: a second look. N. Engl. J. Med. 326:1151.
-
(1992)
N. Engl. J. Med.
, vol.326
, pp. 1151
-
-
Wenzel, R.P.1
-
31
-
-
0022538733
-
Phenotypic comparison of Pseudomonas aeruginosa strains isolated from a variety of clinical isolates
-
Woods, D. E., M. S. Schaffer, H. R. Rabin, G. D. Campbell, and P. A. Sokol. 1986. Phenotypic comparison of Pseudomonas aeruginosa strains isolated from a variety of clinical isolates. J. Clin. Microbiol. 24:260.
-
(1986)
J. Clin. Microbiol.
, vol.24
, pp. 260
-
-
Woods, D.E.1
Schaffer, M.S.2
Rabin, H.R.3
Campbell, G.D.4
Sokol, P.A.5
-
32
-
-
0021795933
-
Role of exoenzyme S in chronic Pseudomonas aeruginosa lung infections
-
Nicas, T. I., D. W. Frank, J. D. Lile, and B. H. Iglewski. 1985. Role of exoenzyme S in chronic Pseudomonas aeruginosa lung infections. Eur. J. Clin. Microbiol. 4:175.
-
(1985)
Eur. J. Clin. Microbiol.
, vol.4
, pp. 175
-
-
Nicas, T.I.1
Frank, D.W.2
Lile, J.D.3
Iglewski, B.H.4
-
33
-
-
0024854885
-
Subinhibitory antibiotics reduce Pseudomonas aeruginosa tissue injury in the rat lung model
-
Grimwood, K., M. To, H. R. Rabin, and D. E. Woods. 1989. Subinhibitory antibiotics reduce Pseudomonas aeruginosa tissue injury in the rat lung model. J. Antimicrob. Chemother. 24:937.
-
(1989)
J. Antimicrob. Chemother.
, vol.24
, pp. 937
-
-
Grimwood, K.1
To, M.2
Rabin, H.R.3
Woods, D.E.4
-
34
-
-
0023936185
-
Alteration of pulmonary structure by Pseudomonas aeruginosa exoenzyme S
-
Woods, D. E., W. S. Hwang, M. S. Shahrabadi, and J. U. Que. 1988. Alteration of pulmonary structure by Pseudomonas aeruginosa exoenzyme S. J. Med. Microbiol. 26:131.
-
(1988)
J. Med. Microbiol.
, vol.26
, pp. 131
-
-
Woods, D.E.1
Hwang, W.S.2
Shahrabadi, M.S.3
Que, J.U.4
-
35
-
-
0030922964
-
Intracellular targeting of exoenzyme S of Pseudomonas aeruginosa via type III-dependent translocation induces phagocytosis resistance, cytotoxicity and disruption of actin microfilaments
-
Frithz-Lindsten, E., Y. Du, R. Rosqvist, and A. Forsberg. 1997. Intracellular targeting of exoenzyme S of Pseudomonas aeruginosa via type III-dependent translocation induces phagocytosis resistance, cytotoxicity and disruption of actin microfilaments. Mol. Microbiol. 25:1125.
-
(1997)
Mol. Microbiol.
, vol.25
, pp. 1125
-
-
Frithz-Lindsten, E.1
Du, Y.2
Rosqvist, R.3
Forsberg, A.4
-
36
-
-
0035171524
-
How the Pseudomonas aeruginosa ExoS toxin downregulates Rac
-
Wurtele, M., E. Wolf, K. J. Pederson, G. Buchwald, M. R. Ahmadian, J. T. Barbieri, and A. Wittinghofer. 2001. How the Pseudomonas aeruginosa ExoS toxin downregulates Rac. Nat. Struct. Biol. 8:23.
-
(2001)
Nat. Struct. Biol.
, vol.8
, pp. 23
-
-
Wurtele, M.1
Wolf, E.2
Pederson, K.J.3
Buchwald, G.4
Ahmadian, M.R.5
Barbieri, J.T.6
Wittinghofer, A.7
-
37
-
-
0030858819
-
Ecto-ADP-ribosyltransferase activity of Pseudomonas aeruginosa exoenzyme S
-
Knight, D. A., and J. T. Barbieri. 1997. Ecto-ADP-ribosyltransferase activity of Pseudomonas aeruginosa exoenzyme S. Infect. Immun. 65:3304.
-
(1997)
Infect. Immun.
, vol.65
, pp. 3304
-
-
Knight, D.A.1
Barbieri, J.T.2
-
38
-
-
0030731178
-
Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon
-
Yahr, T. L., L. M. Mende-Mueller, M. B. Friese, and D. W. Frank. 1997. Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon. J. Bacteriol. 179:7165.
-
(1997)
J. Bacteriol.
, vol.179
, pp. 7165
-
-
Yahr, T.L.1
Mende-Mueller, L.M.2
Friese, M.B.3
Frank, D.W.4
-
39
-
-
0032962344
-
Regulation of ExoS production and secretion by Pseudomonas aeruginosa in response to tissue culture conditions
-
Vallis, A. J., T. L. Vahr, J. T. Barbieri, and D. W. Frank. 1999. Regulation of ExoS production and secretion by Pseudomonas aeruginosa in response to tissue culture conditions. Infect. Immun. 67:914.
-
(1999)
Infect. Immun.
, vol.67
, pp. 914
-
-
Vallis, A.J.1
Vahr, T.L.2
Barbieri, J.T.3
Frank, D.W.4
-
40
-
-
0033579479
-
The N-terminal domain of Pseudomonas aeruginosa exoenzyme S is a GTPase-activating protein for Rho GTPases
-
Goehring, U. M., G. Schmidt, K. J. Pederson, K. Aktories, and J: T. Barbieri. 1999. The N-terminal domain of Pseudomonas aeruginosa exoenzyme S is a GTPase-activating protein for Rho GTPases. J. Biol. Chem. 274:36369.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36369
-
-
Goehring, U.M.1
Schmidt, G.2
Pederson, K.J.3
Aktories, K.4
Barbieri, J.T.5
-
41
-
-
0031816676
-
Pseudomonas aeruginosa exoenzyme S is a mitogen but not a superantigen for human T lymphocytes
-
Bruno, T. F., D. E. Buser, R. M. Syme, D. E. Woods, and C. H. Mody. 1998. Pseudomonas aeruginosa exoenzyme S is a mitogen but not a superantigen for human T lymphocytes. Infect. Immun. 66:3072.
-
(1998)
Infect. Immun.
, vol.66
, pp. 3072
-
-
Bruno, T.F.1
Buser, D.E.2
Syme, R.M.3
Woods, D.E.4
Mody, C.H.5
-
42
-
-
0036521729
-
Distinct fates of monocytes and T cells directly activated by Pseudomonas aeruginosa exoenzyme S
-
Epelman, S., G. G. Neely, L. L. Ma, M. Gjomarkaj, E. Pace, M. Melis, D. E. Woods, and C. H. Mody. 2002. Distinct fates of monocytes and T cells directly activated by Pseudomonas aeruginosa exoenzyme S. J. Leukocyte Biol. 71:458.
-
(2002)
J. Leukocyte Biol.
, vol.71
, pp. 458
-
-
Epelman, S.1
Neely, G.G.2
Ma, L.L.3
Gjomarkaj, M.4
Pace, E.5
Melis, M.6
Woods, D.E.7
Mody, C.H.8
-
43
-
-
0033306494
-
Recombinant Pseudomonas exoenzyme S and exoenzyme S from Pseudomonas aeruginosa strain DG1 share the ability to stimulate T lymphocyte proliferation
-
Bruno, T. F., D. E. Woods, D. G. Storey, and C. H. Mody. 1999. Recombinant Pseudomonas exoenzyme S and exoenzyme S from Pseudomonas aeruginosa strain DG1 share the ability to stimulate T lymphocyte proliferation. Can. J. Microbiol. 45:607.
-
(1999)
Can. J. Microbiol.
, vol.45
, pp. 607
-
-
Bruno, T.F.1
Woods, D.E.2
Storey, D.G.3
Mody, C.H.4
-
44
-
-
0033929391
-
Pseudomonas aeruginosa exoenzyme S induces transcriptional expression of proinflammatory cytokines and chemokines
-
Epelman, S., T. F. Bruno, G. G. Neely, D. E. Woods, and C. H. Mody. 2000. Pseudomonas aeruginosa exoenzyme S induces transcriptional expression of proinflammatory cytokines and chemokines. Infect. Immun. 68:4811.
-
(2000)
Infect. Immun.
, vol.68
, pp. 4811
-
-
Epelman, S.1
Bruno, T.F.2
Neely, G.G.3
Woods, D.E.4
Mody, C.H.5
-
46
-
-
0029099069
-
Functional domains of Pseudomonas aeruginosa exoenzyme S
-
Knight, D. A., V. Finck-Barbancon, S. M. Kulich, and J. T. Barbieri. 1995. Functional domains of Pseudomonas aeruginosa exoenzyme S. Infect. Immun. 63:3182.
-
(1995)
Infect. Immun.
, vol.63
, pp. 3182
-
-
Knight, D.A.1
Finck-Barbancon, V.2
Kulich, S.M.3
Barbieri, J.T.4
-
47
-
-
0029973636
-
FACS-optimized mutants of the green fluorescent protein (GFP)
-
Cormack, B. P., R. H. Valdivia, and S. Falkow. 1996. FACS-optimized mutants of the green fluorescent protein (GFP). Gene 173:33.
-
(1996)
Gene
, vol.173
, pp. 33
-
-
Cormack, B.P.1
Valdivia, R.H.2
Falkow, S.3
-
48
-
-
0034662239
-
Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine Toll-like receptor 2
-
Hirschfeld, M., Y. Mil, J. H. Weis, S. N. Vogel, and J. J. Weis. 2000. Cutting edge: repurification of lipopolysaccharide eliminates signaling through both human and murine Toll-like receptor 2. J. Immunol. 165:618.
-
(2000)
J. Immunol.
, vol.165
, pp. 618
-
-
Hirschfeld, M.1
Mil, Y.2
Weis, J.H.3
Vogel, S.N.4
Weis, J.J.5
-
49
-
-
0033027546
-
ADP-ribosylation of oncogenic Ras proteins by Pseudomonas aeruginosa exoenzyme S in vivo
-
Vincent, T. S., J. E. Fraylick, E. M. McGuffie, and J. C. Olson. 1999. ADP-ribosylation of oncogenic Ras proteins by Pseudomonas aeruginosa exoenzyme S in vivo. Mol. Microbiol. 32:1054.
-
(1999)
Mol. Microbiol.
, vol.32
, pp. 1054
-
-
Vincent, T.S.1
Fraylick, J.E.2
McGuffie, E.M.3
Olson, J.C.4
-
50
-
-
0032476602
-
CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by nonspecific endocytosis ard endosomal maturation
-
Hacker, H., H. Mischak, T. Miethke, S. Liptay, R. Schmid, T. Sparwasser, K. Heeg, G. B. Lipford, and H. Wagner. 1998. CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by nonspecific endocytosis ard endosomal maturation. EMBO J. 17:6230.
-
(1998)
EMBO J.
, vol.17
, pp. 6230
-
-
Hacker, H.1
Mischak, H.2
Miethke, T.3
Liptay, S.4
Schmid, R.5
Sparwasser, T.6
Heeg, K.7
Lipford, G.B.8
Wagner, H.9
-
51
-
-
0034730624
-
Epidermal growth factor-mediated caveolin recruitment to early endosomes and MAPK activation: Role of cholesterol and actin cytoskeleton
-
Pol, A., A. Lu, M. Pons, S. Peiro, and C. Enrich. 2000. Epidermal growth factor-mediated caveolin recruitment to early endosomes and MAPK activation: role of cholesterol and actin cytoskeleton. J. Biol. Chem. 275:30566.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30566
-
-
Pol, A.1
Lu, A.2
Pons, M.3
Peiro, S.4
Enrich, C.5
-
52
-
-
0035871626
-
Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators
-
166.5161
-
Lehner, M. D., S. Morath, K. S. Michelsen, R. R. Schumann, and T. Härtung. 2001. Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators. J. Immunol. 166.5161.
-
(2001)
J. Immunol.
-
-
Lehner, M.D.1
Morath, S.2
Michelsen, K.S.3
Schumann, R.R.4
Härtung, T.5
-
53
-
-
0033021299
-
Lipopolysaccharide tolerance in murine peritoneal macrophages induces downregulation of the lipopolysaccharide signal transduction pathway through mitogen-activated protein kinase and nuclear factor-κB cascades, but not lipopolysaccharide-incorporation steps
-
Tominaga, K., S. Saito, M. Matsuura, and M. Nakano. 1999. Lipopolysaccharide tolerance in murine peritoneal macrophages induces downregulation of the lipopolysaccharide signal transduction pathway through mitogen-activated protein kinase and nuclear factor-κB cascades, but not lipopolysaccharide-incorporation steps. Biochim. Biophys. Acta 1450:130.
-
(1999)
Biochim. Biophys. Acta
, vol.1450
, pp. 130
-
-
Tominaga, K.1
Saito, S.2
Matsuura, M.3
Nakano, M.4
-
54
-
-
0033968625
-
Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades
-
Takeuchi, O., K. Takeda, K. Hoshino, O. Adachi, T. Ogawa, and S. Akira. 2000. Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades. Int. Immunol. 12:113.
-
(2000)
Int. Immunol.
, vol.12
, pp. 113
-
-
Takeuchi, O.1
Takeda, K.2
Hoshino, K.3
Adachi, O.4
Ogawa, T.5
Akira, S.6
-
55
-
-
0032806197
-
Lipopolysaccharide-induced tumor necrosis factor α production by human monocytes involves the raf-1/MEK1-MEK2/ERK1-ERK2 pathway
-
van der Bruggen, T., S. Nijenhuis, E. van Raaij, J. Verhoef, and B. S. van Asbeck. 1999. Lipopolysaccharide-induced tumor necrosis factor α production by human monocytes involves the raf-1/MEK1-MEK2/ERK1-ERK2 pathway. Infect. Immun. 67:3824.
-
(1999)
Infect. Immun.
, vol.67
, pp. 3824
-
-
Van Der Bruggen, T.1
Nijenhuis, S.2
Van Raaij, E.3
Verhoef, J.4
Van Asbeck, B.S.5
-
56
-
-
0033913828
-
Intracellular localization and processing of Pseudomonas aeruginosa ExoS in eukaryotic cells
-
Pederson, K. J., S. Pal, A. J. Valus, D. W. Frank, and J. T. Barbieri. 2000. Intracellular localization and processing of Pseudomonas aeruginosa ExoS in eukaryotic cells. Mol. Microbiol. 37:287.
-
(2000)
Mol. Microbiol.
, vol.37
, pp. 287
-
-
Pederson, K.J.1
Pal, S.2
Valus, A.J.3
Frank, D.W.4
Barbieri, J.T.5
-
57
-
-
0032805052
-
Pseudomonas aeruginosa exoenzyme S stimulates murine lymphocyte proliferation in vitro
-
Barclay, N. G., J. C. Spurrell, T. F. Bruno, D. G. Storey, D. E. Woods, and C. H. Mody. 1999. Pseudomonas aeruginosa exoenzyme S stimulates murine lymphocyte proliferation in vitro. Infect. Immun. 67:4613.
-
(1999)
Infect. Immun.
, vol.67
, pp. 4613
-
-
Barclay, N.G.1
Spurrell, J.C.2
Bruno, T.F.3
Storey, D.G.4
Woods, D.E.5
Mody, C.H.6
-
58
-
-
0028954763
-
Pseudomonas aeruginosa exoenzyme S induces proliferation of human T lymphocytes
-
Mody, C. H., D. E. Buser, R. M. Syme, and D. E. Woods. 1995. Pseudomonas aeruginosa exoenzyme S induces proliferation of human T lymphocytes. Infect. Immun. 63:1800.
-
(1995)
Infect. Immun.
, vol.63
, pp. 1800
-
-
Mody, C.H.1
Buser, D.E.2
Syme, R.M.3
Woods, D.E.4
-
59
-
-
0036318851
-
Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
-
Ahmad-Nejad, P., H. Hacker, M. Rutz, S. Bauer, R. M. Vabulas, and H. Wagner. 2002. Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur. J. Immunol. 32:1958.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 1958
-
-
Ahmad-Nejad, P.1
Hacker, H.2
Rutz, M.3
Bauer, S.4
Vabulas, R.M.5
Wagner, H.6
-
60
-
-
0033618630
-
Cell activation and apoptosis by bacterial lipoproteins through Toll-like receptor-2
-
Aliprantis, A. O., R. B. Yang, M. R. Mark, S. Suggett, B. Devaux, J. D. Radolf, G. R. Klimpel, P. Godowski, and A. Zychlinsky. 1999. Cell activation and apoptosis by bacterial lipoproteins through Toll-like receptor-2. Science 285:736.
-
(1999)
Science
, vol.285
, pp. 736
-
-
Aliprantis, A.O.1
Yang, R.B.2
Mark, M.R.3
Suggett, S.4
Devaux, B.5
Radolf, J.D.6
Klimpel, G.R.7
Godowski, P.8
Zychlinsky, A.9
-
62
-
-
0029048442
-
Peptidoglycan induces transcription and secretion of TNF-α and activation of lyn, extracellular signal-regulated kinase, and rsk signal transduction proteins in mouse macrophages
-
Gupta, D., Y. P. Jin, and R. Dziarski. 1995. Peptidoglycan induces transcription and secretion of TNF-α and activation of lyn, extracellular signal-regulated kinase, and rsk signal transduction proteins in mouse macrophages. J. Immunol. 155:2620.
-
(1995)
J. Immunol.
, vol.155
, pp. 2620
-
-
Gupta, D.1
Jin, Y.P.2
Dziarski, R.3
-
63
-
-
0036180692
-
Cytokine induction by purified lipoteichoic acids from various bacterial species-role of LBP, SCD14, CD14 and failure to induce IL-12 and subsequent IFN-γ release
-
Hermann, C., I. Spreitzer, N. W. Schroder, S. Morath, M. D. Lehner, W. Fischer, C. Schutt, R. R. Schumann, and T. Hartung. 2002. Cytokine induction by purified lipoteichoic acids from various bacterial species-role of LBP, SCD14, CD14 and failure to induce IL-12 and subsequent IFN-γ release. Eur. J. Immunol. 32:541.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 541
-
-
Hermann, C.1
Spreitzer, I.2
Schroder, N.W.3
Morath, S.4
Lehner, M.D.5
Fischer, W.6
Schutt, C.7
Schumann, R.R.8
Hartung, T.9
-
64
-
-
0035865058
-
Mycoplasma fermentons lipoprotein M161Ag-induced cell activation is mediated by Toll-like receptor 2: Role of N-terminal hydrophobic portion in its multiple functions
-
Nishiguchi, M., M. Matsumoto, T. Takao, M. Hoshino, Y. Shimonishi, S. Tsuji, N. A. Begum, O. Takeuchi, S. Akira, K. Toyoshima, and T. Seya. 2001. Mycoplasma fermentons lipoprotein M161Ag-induced cell activation is mediated by Toll-like receptor 2: role of N-terminal hydrophobic portion in its multiple functions. J. Immunol. 166:2610.
-
(2001)
J. Immunol.
, vol.166
, pp. 2610
-
-
Nishiguchi, M.1
Matsumoto, M.2
Takao, T.3
Hoshino, M.4
Shimonishi, Y.5
Tsuji, S.6
Begum, N.A.7
Takeuchi, O.8
Akira, S.9
Toyoshima, K.10
Seya, T.11
-
65
-
-
0018331361
-
Lymphocytes binding and T cell mitogenic properties of group A streptococcal lipoteichoic acid
-
Beachey, E. H., J. B. Dale, S. Grebe, A. Ahmed, W. A. Simpson, and I. Ofek. 1979. Lymphocytes binding and T cell mitogenic properties of group A streptococcal lipoteichoic acid. J. Immunol. 122:189.
-
(1979)
J. Immunol.
, vol.122
, pp. 189
-
-
Beachey, E.H.1
Dale, J.B.2
Grebe, S.3
Ahmed, A.4
Simpson, W.A.5
Ofek, I.6
-
66
-
-
0020053235
-
Cell walls, peptidoglycans, and teichoic acids of Gram-positive bacteria as polyclonal inducers and immunomodulators of proliferative and lymphokine responses of human B and T lymphocytes
-
Rasanen, L., and H. Arvilommi. 1982. Cell walls, peptidoglycans, and teichoic acids of Gram-positive bacteria as polyclonal inducers and immunomodulators of proliferative and lymphokine responses of human B and T lymphocytes. Infect. Immun. 35:523.
-
(1982)
Infect. Immun.
, vol.35
, pp. 523
-
-
Rasanen, L.1
Arvilommi, H.2
-
68
-
-
0035213773
-
Effect of cross-tolerance between endotoxin and TNF-α or IL-1β on cellular signaling and mediator production
-
Ferlito, M., O. G. Romanenko, S. Ashton, F. Squadrito, P. V. Halushka, and J. A. Cook. 2001. Effect of cross-tolerance between endotoxin and TNF-α or IL-1β on cellular signaling and mediator production. J. Leukocyte Biol. 70:821.
-
(2001)
J. Leukocyte Biol.
, vol.70
, pp. 821
-
-
Ferlito, M.1
Romanenko, O.G.2
Ashton, S.3
Squadrito, F.4
Halushka, P.V.5
Cook, J.A.6
-
69
-
-
0036521725
-
Toll-like receptor 9 mediates CpG-DNA signaling
-
Chuang, T. H., J. Lee, L. Kline, J. C. Mathison, and R. J. Ulevitch. 2002. Toll-like receptor 9 mediates CpG-DNA signaling. J. Leukocyte Biol. 71:538.
-
(2002)
J. Leukocyte Biol.
, vol.71
, pp. 538
-
-
Chuang, T.H.1
Lee, J.2
Kline, L.3
Mathison, J.C.4
Ulevitch, R.J.5
-
70
-
-
0035877718
-
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex: Transfer from CD14 to TLR4 and MD-2
-
da Silva, C. J., K. Soldau, U. Christen, P. S. Tobias, and R. J. Ulevitch. 2001. Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex: transfer from CD14 to TLR4 and MD-2. J. Biol Chem. 276:21129.
-
(2001)
J. Biol Chem.
, vol.276
, pp. 21129
-
-
Da Silva, C.J.1
Soldau, K.2
Christen, U.3
Tobias, P.S.4
Ulevitch, R.J.5
-
71
-
-
0034292364
-
Lipopolysaccharide induces physical proximity between CD14 and Toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-κB
-
Jiang, Q., S. Akashi, K. Miyake, and H. R. Petty. 2000. Lipopolysaccharide induces physical proximity between CD14 and Toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-κB. J. Immunol. 165:3541.
-
(2000)
J. Immunol.
, vol.165
, pp. 3541
-
-
Jiang, Q.1
Akashi, S.2
Miyake, K.3
Petty, H.R.4
-
72
-
-
0035070198
-
CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin
-
Basu, S., R. J. Binder, T. Ramalingam, and P. K. Srivastava. 2001. CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin. Immunity 14:303.
-
(2001)
Immunity
, vol.14
, pp. 303
-
-
Basu, S.1
Binder, R.J.2
Ramalingam, T.3
Srivastava, P.K.4
-
73
-
-
0032544089
-
A peptidoglycan recognition protein in innate immunity conserved from insects to humans
-
Kang, D., G. Liu, A. Lundstrom, E. Gelius, and H. Steiner. 1998. A peptidoglycan recognition protein in innate immunity conserved from insects to humans. Proc. Natl. Acad. Sci. USA 95:10078.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 10078
-
-
Kang, D.1
Liu, G.2
Lundstrom, A.3
Gelius, E.4
Steiner, H.5
-
75
-
-
0032533817
-
CD11/CD18 and CD14 share a common lipid A signaling pathway
-
Ingalls, R. R., B. G. Monks, R. J. Savedra, W. J. Christ, R. L. Delude, A. E. Medvedev, T. Espevik, and D. T. Golenbock. 1998. CD11/CD18 and CD14 share a common lipid A signaling pathway. J. Immunol. 161:5413.
-
(1998)
J. Immunol.
, vol.161
, pp. 5413
-
-
Ingalls, R.R.1
Monks, B.G.2
Savedra, R.J.3
Christ, W.J.4
Delude, R.L.5
Medvedev, A.E.6
Espevik, T.7
Golenbock, D.T.8
-
76
-
-
0034671772
-
Synergy and cross-tolerance between Toll-like receptor (TLR 2-and TLR4-mediated signaling pathways
-
Sato, S., F. Nomura, T. Kawai, O. Takeuchi, P. F. Muhlradt, K. Takeda, and S. Akira. 2000. Synergy and cross-tolerance between Toll-like receptor (TLR 2-and TLR4-mediated signaling pathways. J. Immunol. 165:7096.
-
(2000)
J. Immunol.
, vol.165
, pp. 7096
-
-
Sato, S.1
Nomura, F.2
Kawai, T.3
Takeuchi, O.4
Muhlradt, P.F.5
Takeda, K.6
Akira, S.7
-
77
-
-
0033023632
-
Interruption of multiple cellular processes in HT-29 epithelial cells by Pseudomonas aeruginosa exoenzyme S
-
Olson, J. C, J. E. Fraylick, E. M. McGuffie, K. M. Dolan, T. L. Yahr, D. W. Frank, and T. S. Vincent. 1999. Interruption of multiple cellular processes in HT-29 epithelial cells by Pseudomonas aeruginosa exoenzyme S. Infect. Immun. 67:2847.
-
(1999)
Infect. Immun.
, vol.67
, pp. 2847
-
-
Olson, J.C.1
Fraylick, J.E.2
McGuffie, E.M.3
Dolan, K.M.4
Yahr, T.L.5
Frank, D.W.6
Vincent, T.S.7
-
78
-
-
0028842110
-
Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors
-
Daeron, M., O. Malbec, S. Latour, M. Arock, and W. H. Fridman. 1995. Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors. J. Clin. Invest. 95:577.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 577
-
-
Daeron, M.1
Malbec, O.2
Latour, S.3
Arock, M.4
Fridman, W.H.5
|