Novel 2-aminotetralin and 3-aminochroman derivatives as selective serotonin 5-HT7 receptor agonists and antagonists

Journal of Medicinal Chemistry

Volumn 47, Issue 16, 2004, Pages 3927-3930

  Holmberg, Pär ^a   Sohn, Daniel ^b   Leideborg, Robert ^b   Caldirola, Patrizia ^a,c   Zlatoidsky, Pavel ^a,d   Hanson, Sverker ^b   Mohell, Nina ^b,c   Rosqvist, Susanne ^b   Nordvall, Gunnar ^b   Johansson, Anette M ^a,e   Johansson, Rolf ^a,b  

^a UPPSALA UNIVERSITY   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

^c BIOVITRUM AB   (Sweden)

^d ASTRAZENECA R AND D   (Sweden)

^e ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOTETRALIN DERIVATIVE; 3 AMINOCHROMAN DERIVATIVE; CHROMAN DERIVATIVE; G PROTEIN COUPLED RECEPTOR; SB 656104; SB 691673; SEROTONIN 7 RECEPTOR; SEROTONIN 7 RECEPTOR AGONIST; SEROTONIN 7 RECEPTOR ANTAGONIST; TETRALIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; NANOTECHNOLOGY; NONHUMAN; RAT; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM; STRUCTURE ACTIVITY RELATION;

ANIMALS; CHO CELLS; CHROMANS; CRICETINAE; CYCLIC AMP; LIGANDS; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDRONAPHTHALENES;

EID: 3242768358     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0498102     Document Type: Article

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