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Volumn 16, Issue 7, 2004, Pages 1001-1007

An increased frequency of autoantibody-inducing CD4+ T cells in pre-diseased lupus-prone mice

Author keywords

Autoantibodies; B lymphocytes; Lupus; T lymphocytes

Indexed keywords

ANTINUCLEAR ANTIBODY; AUTOANTIBODY; CD4 ANTIGEN;

EID: 3242714248     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxh101     Document Type: Article
Times cited : (7)

References (39)
  • 1
    • 0034816964 scopus 로고    scopus 로고
    • Delineating the genetic basis of systemic lupus erythematosus
    • Walkeland, E. K., Liu, K., Graham, R. R. and Behrens, T. W. 2001. Delineating the genetic basis of systemic lupus erythematosus. Immunity 15:397.
    • (2001) Immunity , vol.15 , pp. 397
    • Walkeland, E.K.1    Liu, K.2    Graham, R.R.3    Behrens, T.W.4
  • 2
    • 0035555022 scopus 로고    scopus 로고
    • The genetics of complex autoimmune diseases: Non-MHC susceptibility genes
    • Wanstrat, A. and Walkeland, E. 2001. The genetics of complex autoimmune diseases: non-MHC susceptibility genes. Nat. Immunol. 2:802.
    • (2001) Nat. Immunol. , vol.2 , pp. 802
    • Wanstrat, A.1    Walkeland, E.2
  • 3
    • 0034815595 scopus 로고    scopus 로고
    • Murine lupus genetics: Lessons learned
    • Mohan, C. 2001. Murine lupus genetics: lessons learned. Curr. Opin. Pheumatol. 13:352.
    • (2001) Curr. Opin. Pheumatol. , vol.13 , pp. 352
    • Mohan, C.1
  • 4
    • 0034610973 scopus 로고    scopus 로고
    • High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: Mechanisms of selection of the self-reactive repertoire
    • Anderson, A. C., Nicholson, L. B., Legge, K. L., Turchin, V., Zaghouani, H. and Kuchroo, V. K. 2000. High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire. J. Exp. Med. 191:761.
    • (2000) J. Exp. Med. , vol.191 , pp. 761
    • Anderson, A.C.1    Nicholson, L.B.2    Legge, K.L.3    Turchin, V.4    Zaghouani, H.5    Kuchroo, V.K.6
  • 5
    • 0033984067 scopus 로고    scopus 로고
    • Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells
    • Klein, L., Klugmann, M., Nave, K. A., Tuohy, V. K. and Kyewski, B. 2000. Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells. Nat. Med. 6:56.
    • (2000) Nat. Med. , vol.6 , pp. 56
    • Klein, L.1    Klugmann, M.2    Nave, K.A.3    Tuohy, V.K.4    Kyewski, B.5
  • 6
    • 0035175577 scopus 로고    scopus 로고
    • A defect in central tolerance in NOD mice
    • Kishimoto, H. and Sprent, J. 2001. A defect in central tolerance in NOD mice. Nat. Immunol. 2:1025.
    • (2001) Nat. Immunol. , vol.2 , pp. 1025
    • Kishimoto, H.1    Sprent, J.2
  • 7
    • 0018118725 scopus 로고
    • Individual antigen-specific T lymphocytes: Helper function in enabling the expression of multiple antibody isotypes
    • Pierce, S. K., Cancro, M. P. and Klinman, N. R. 1978. Individual antigen-specific T lymphocytes: helper function in enabling the expression of multiple antibody isotypes. J. Exp. Med. 148:759.
    • (1978) J. Exp. Med. , vol.148 , pp. 759
    • Pierce, S.K.1    Cancro, M.P.2    Klinman, N.R.3
  • 9
    • 0035920510 scopus 로고    scopus 로고
    • Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells
    • Bensinger, S. J., Bandeira, A., Jordan, M. S., Caton, A. J. and Laufer, T. M. 2001. Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells. J. Exp. Med. 194:427.
    • (2001) J. Exp. Med. , vol.194 , pp. 427
    • Bensinger, S.J.1    Bandeira, A.2    Jordan, M.S.3    Caton, A.J.4    Laufer, T.M.5
  • 10
    • 0347986780 scopus 로고    scopus 로고
    • Activation of diverse repertoires of autoreactive T cells enhances the loss of anti-dsDNA B cell tolerance
    • Busser, B. W., Adair, B. S., Erikson, J. and Laufer, T. M. 2003. Activation of diverse repertoires of autoreactive T cells enhances the loss of anti-dsDNA B cell tolerance. J. Clin. Invest. 112:1361.
    • (2003) J. Clin. Invest. , vol.112 , pp. 1361
    • Busser, B.W.1    Adair, B.S.2    Erikson, J.3    Laufer, T.M.4
  • 11
    • 0025011972 scopus 로고
    • Subnucleosome structures as substrates in enzyme-linked immunosorbent assays
    • Burlingame, R. W. and Rubin, R. L. 1990. Subnucleosome structures as substrates in enzyme-linked immunosorbent assays. J. Immunol. Methods 134:187.
    • (1990) J. Immunol. Methods , vol.134 , pp. 187
    • Burlingame, R.W.1    Rubin, R.L.2
  • 12
    • 0026772133 scopus 로고
    • A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells
    • Noelle, R. J., Roy, M., Shepherd, D. M., Stamenkovic, I., Ledbetter, J. A. and Aruffo, A. 1992. A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. Proc. Natl Acad. Sci. USA 89:6550.
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 6550
    • Noelle, R.J.1    Roy, M.2    Shepherd, D.M.3    Stamenkovic, I.4    Ledbetter, J.A.5    Aruffo, A.6
  • 14
    • 0018935423 scopus 로고
    • Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice
    • Steinberg, A. D., Roths, J. B., Murphy, E. D., Steinberg, R. T. and Raveche, E. S. 1980. Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice. J. Immunol. 125:871.
    • (1980) J. Immunol. , vol.125 , pp. 871
    • Steinberg, A.D.1    Roths, J.B.2    Murphy, E.D.3    Steinberg, R.T.4    Raveche, E.S.5
  • 15
    • 0021940256 scopus 로고
    • Treatment of murine lupus with monoclonal anti-T cell antibody
    • Wofsy, D., Ledbetter, J. A., Hendler, P. L. and Seaman, W. E. 1985. Treatment of murine lupus with monoclonal anti-T cell antibody. J. Immunol. 134:852.
    • (1985) J. Immunol. , vol.134 , pp. 852
    • Wofsy, D.1    Ledbetter, J.A.2    Hendler, P.L.3    Seaman, W.E.4
  • 16
    • 0028326095 scopus 로고
    • Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice
    • Jevnikar, A. M., Grusby, M. J. and Glimcher, L. H. 1994. Prevention of nephritis in major histocompatibility complex class II-deficient MRL-lpr mice. J. Exp. Med. 179:1137.
    • (1994) J. Exp. Med. , vol.179 , pp. 1137
    • Jevnikar, A.M.1    Grusby, M.J.2    Glimcher, L.H.3
  • 17
    • 0019475616 scopus 로고
    • Multiple B cell stimulation by individual antigen-specific T lymphocytes
    • Pierce, S. K. and Klinman, N. R. 1981. Multiple B cell stimulation by individual antigen-specific T lymphocytes. Eur. J. Immunol. 11:71.
    • (1981) Eur. J. Immunol. , vol.11 , pp. 71
    • Pierce, S.K.1    Klinman, N.R.2
  • 20
    • 0023223942 scopus 로고
    • Clonal analysis of the anti-DNA repertoire of murine B lymphocytes
    • Conger, J. D., Pike, B. L. and Nossal, G. J. 1987. Clonal analysis of the anti-DNA repertoire of murine B lymphocytes. Proc. Natl Acad. Sci. USA 84:2931.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 2931
    • Conger, J.D.1    Pike, B.L.2    Nossal, G.J.3
  • 22
    • 0029939451 scopus 로고    scopus 로고
    • Autoimmune lpr/lpr mice deficient in CD40 ligand: Spontaneous Ig class switching with dichotomy of autoantilbody responses
    • Ma, J., Xu, J., Madaio, M. P., Peng, Q., Zhang, J., Grewal, I. S., Flavell, R. A. and Craft, J. 1996. Autoimmune lpr/lpr mice deficient in CD40 ligand: spontaneous Ig class switching with dichotomy of autoantilbody responses. J. Immunol. 157:417.
    • (1996) J. Immunol. , vol.157 , pp. 417
    • Ma, J.1    Xu, J.2    Madaio, M.P.3    Peng, Q.4    Zhang, J.5    Grewal, I.S.6    Flavell, R.A.7    Craft, J.8
  • 23
    • 0028852328 scopus 로고
    • Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis
    • Mohan, C., Shi, Y., Laman, J. D. and Datta, S. K. 1995. Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. J. Immunol. 154:1470.
    • (1995) J. Immunol. , vol.154 , pp. 1470
    • Mohan, C.1    Shi, Y.2    Laman, J.D.3    Datta, S.K.4
  • 24
    • 0035171545 scopus 로고    scopus 로고
    • Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
    • Derbinski, J., Schulte, A., Kyewski, B. and Klein, L. 2001. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self. Nat. Immunol. 2:1032.
    • (2001) Nat. Immunol. , vol.2 , pp. 1032
    • Derbinski, J.1    Schulte, A.2    Kyewski, B.3    Klein, L.4
  • 26
    • 1842870735 scopus 로고    scopus 로고
    • The chronic graft-versus-host model of systemic autoimmunity
    • Eisenberg, R. 2003. The chronic graft-versus-host model of systemic autoimmunity. Curr. Dir. Autoimmun. 6:228.
    • (2003) Curr. Dir. Autoimmun. , vol.6 , pp. 228
    • Eisenberg, R.1
  • 27
    • 0033151971 scopus 로고    scopus 로고
    • Genetic dissection of Sle pathogenesis: Sle3 on murine chromosome 7 impacts T cell activation, differentiation and cell death
    • Mohan, C., Yu, Y., Morel, L., Yang, P. and Wakeland, E. K. 1999. Genetic dissection of Sle pathogenesis: Sle3 on murine chromosome 7 impacts T cell activation, differentiation and cell death. J. Immunol. 162:6492.
    • (1999) J. Immunol. , vol.162 , pp. 6492
    • Mohan, C.1    Yu, Y.2    Morel, L.3    Yang, P.4    Wakeland, E.K.5
  • 28
    • 0035808778 scopus 로고    scopus 로고
    • CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: A model to explain spontaneous T cell activation in lupus
    • Vratsanos, G. S., Jung, S., Park, Y. M. and Craft, J. 2001. CD4(+) T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: a model to explain spontaneous T cell activation in lupus. J. Exp. Med. 193:329.
    • (2001) J. Exp. Med. , vol.193 , pp. 329
    • Vratsanos, G.S.1    Jung, S.2    Park, Y.M.3    Craft, J.4
  • 29
    • 0036560022 scopus 로고    scopus 로고
    • Abnormal T cell signal transduction in systemic lupus erythematosus
    • Kammer, G. M., Perl, A., Richardson, B. C. and Tsokos, G. C. 2002. Abnormal T cell signal transduction in systemic lupus erythematosus. Arthritis Rheum. 46:1139.
    • (2002) Arthritis Rheum. , vol.46 , pp. 1139
    • Kammer, G.M.1    Perl, A.2    Richardson, B.C.3    Tsokos, G.C.4
  • 30
    • 0026671268 scopus 로고
    • Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice
    • Zhou, T., Bluethmann, H., Zhang, J., Edwards, C. K. III and Mountz, J. D. 1992. Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice. J. Exp. Med. 176:1063.
    • (1992) J. Exp. Med. , vol.176 , pp. 1063
    • Zhou, T.1    Bluethmann, H.2    Zhang, J.3    Edwards III, C.K.4    Mountz, J.D.5
  • 32
    • 0027266844 scopus 로고
    • Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice
    • Scott, D. E., Kisch, W. J. and Steinberg, A. D. 1993. Studies of T cell deletion and T cell anergy following in vivo administration of SEB to normal and lupus-prone mice. J. Immunol. 150:664.
    • (1993) J. Immunol. , vol.150 , pp. 664
    • Scott, D.E.1    Kisch, W.J.2    Steinberg, A.D.3
  • 33
    • 0032402260 scopus 로고    scopus 로고
    • Central T cell tolerance in lupus-prone mice: Influence of autoimmune background and the lpr mutation
    • Fatenejad, S., Peng, S. L., Disorbo, O. and Craft, J. 1998. Central T cell tolerance in lupus-prone mice: influence of autoimmune background and the lpr mutation. J. Immunol. 161:6427.
    • (1998) J. Immunol. , vol.161 , pp. 6427
    • Fatenejad, S.1    Peng, S.L.2    Disorbo, O.3    Craft, J.4
  • 34
    • 0037417978 scopus 로고    scopus 로고
    • Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation
    • Zhan, Y., Purton, J. F., Godfrey, D. I., Cole, T. J., Heath, W. R. and Lew, A. M. 2003. Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation. Proc. Natl Acad. Sci. USA 100: 1197.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 1197
    • Zhan, Y.1    Purton, J.F.2    Godfrey, D.I.3    Cole, T.J.4    Heath, W.R.5    Lew, A.M.6
  • 35
    • 0028294682 scopus 로고
    • Positive and negative thymocyte selection induced by different concentrations of a single peptide
    • Sebzda, E., Wallace, V. A., Mayer, J., Yeung, R. S., Mak, T. W. and Ohashi, P. S. 1994. Positive and negative thymocyte selection induced by different concentrations of a single peptide. Science 263:1615.
    • (1994) Science , vol.263 , pp. 1615
    • Sebzda, E.1    Wallace, V.A.2    Mayer, J.3    Yeung, R.S.4    Mak, T.W.5    Ohashi, P.S.6
  • 36
    • 0036595050 scopus 로고    scopus 로고
    • T-cell signalling and autoimmunity: Molecular mechanisms of disease
    • Ohashi, P. S. 2002. T-cell signalling and autoimmunity: molecular mechanisms of disease. Nat. Rev. Immunol. 2:427.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 427
    • Ohashi, P.S.1
  • 37
    • 0037438466 scopus 로고    scopus 로고
    • CD4+ T cells from lupus-prone mice avoid antigen-specific tolerance induction in vivo
    • Bouzahzah, F., Jung, S. and Craft, J. 2003. CD4+ T cells from lupus-prone mice avoid antigen-specific tolerance induction in vivo. J. Immunol. 170:741.
    • (2003) J. Immunol. , vol.170 , pp. 741
    • Bouzahzah, F.1    Jung, S.2    Craft, J.3
  • 38
    • 0031179651 scopus 로고    scopus 로고
    • Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity
    • Mohan, C., Morel, L., Yang, P. and Walkeland, E. K. 1997. Genetic dissection of systemic lupus erythematosus pathogenesis: Sle2 on murine chromosome 4 leads to B cell hyperactivity. J. Immunol. 159:454.
    • (1997) J. Immunol. , vol.159 , pp. 454
    • Mohan, C.1    Morel, L.2    Yang, P.3    Walkeland, E.K.4
  • 39
    • 0032520923 scopus 로고    scopus 로고
    • Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes
    • Mohan, C., Alas, E., Morel, L., Yang, P. and Wakeland, E. K. 1998. Genetic dissection of SLE pathogenesis. Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes. J. Clin. Invest. 101:1362.
    • (1998) J. Clin. Invest. , vol.101 , pp. 1362
    • Mohan, C.1    Alas, E.2    Morel, L.3    Yang, P.4    Wakeland, E.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.