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ChemBioChem

Volumn 7, Issue 2, 2006, Pages 351-358

Unexpected oxidation of a depsipeptide substrate analogue in crystalline isopenicillin N synthase

(5) Daruzzaman, Adam a Clifton, Ian J a Adlington, Robert M a Baldwin, Jack E a Rutledge, Peter J b

a UNIVERSITY OF OXFORD (United Kingdom)

b UNIVERSITY COLLEGE DUBLIN (Ireland)

Author keywords

Antibiotics; Biosynthesis; Crystallography; Enzyme mechanism; Metalloenzymes; Non heme iron

Indexed keywords

CARBENE; CYSTEINE DERIVATIVE; DEPSIPEPTIDE; ESTER DERIVATIVE; ISOPENICILLIN N SYNTHETASE; OXIDOREDUCTASE; PENICILLIN DERIVATIVE; THIOL DERIVATIVE; VALERIC ACID DERIVATIVE;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE COMPLEX; OXIDATION; PRIORITY JOURNAL; REACTION ANALYSIS; STEREOSPECIFICITY; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DEPSIPEPTIDES; ESTERS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; OXIDOREDUCTASES; PROTEIN CONFORMATION;

EID: 32344453873 PISSN: 14394227 EISSN: None Source Type: Journal
DOI: 10.1002/cbic.200500282 Document Type: Article

Times cited : (26)

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