Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction

Chemistry and Biology

Volumn 8, Issue 12, 2001, Pages 1231-1237

  Ogle, James M ^a   Clifton, Ian J ^a   Rutledge, Peter J ^a   Elkins, Jonathan M ^a   Burzlaff, Nicolai I ^a   Adlington, Robert M ^a   Roach, Peter L ^b   Baldwin, Jack E ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Enzymic oxidation; High pressure oxygen; Non haem iron enzyme; Penicillin biosynthesis; Time resolved crystallography

Indexed keywords

ISOPENICILLIN N SYNTHETASE; OXIDOREDUCTASE;

ARTICLE; CHEMISTRY; ENZYME SPECIFICITY; OXIDATION REDUCTION REACTION; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; OXIDATION-REDUCTION; OXIDOREDUCTASES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T;

EID: 0035542858     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(01)00090-4     Document Type: Article

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