Inhibition of T cell proliferation by selective block of Ca2+-activated K+ channels

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 19, 1999, Pages 10917-10921

  Jensen, Bo Skaaning ^a,b   Ødum, Niels ^c   Jørgensen, Nanna Koschmieder ^b   Christophersen, Palle ^a   Olesen, Søren Peter ^a,b  

^a NEUROSEARCH A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; CANDIDA ANTIGEN; CHARYBDOTOXIN; CLOTRIMAZOLE; CONCANAVALIN A; CYCLOSPORIN A; GAMMA INTERFERON; KETOCONAZOLE; NITRENDIPINE; PHYTOHEMAGGLUTININ; POTASSIUM CHANNEL; TETANUS TOXIN;

ARTICLE; CALCIUM HOMEOSTASIS; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; LYMPHOCYTE PROLIFERATION; MITOSIS INHIBITION; MOLECULAR DYNAMICS; POTASSIUM CURRENT; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; VOLTAGE CLAMP;

CALCIUM; CALCIUM CHANNEL BLOCKERS; CELLS, CULTURED; CLOTRIMAZOLE; CONCANAVALIN A; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCHEMISTRY; ENZYME INHIBITORS; GROWTH INHIBITORS; HUMANS; INTERFERON TYPE II; KETOCONAZOLE; LYMPHOCYTE ACTIVATION; NITRENDIPINE; PATCH-CLAMP TECHNIQUES; PHYTOHEMAGGLUTININS; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; T-LYMPHOCYTES; TETANUS TOXIN; TIME FACTORS;

CANDIDA; CANDIDA ALBICANS;

EID: 0032873676     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.19.10917     Document Type: Article

References (12)

1. Ishii, T. M., Silvia, C., Hirschberg, B., Bond, C. T., Adelman, J. P. & Maylie, J. (1997) Proc. Natl. Acad. Sci. USA 94, 11651-11656.
2. Jensen, B. S., Strøbæk, D., Christophersen, P., Jørgensen, T. D., Hansen, C., Silahtaroglu, A., Olesen, S.-P. & Ahring, P. K. (1998) Am. J. Physiol. 275, C848-C856.
3. Logsdon, N. J., Kang, J., Togo, J. A., Christian, E. P. & Aiyar, J. (1997) J. Biol. Chem. 272, 32723-32726.
4. Fanger, C. M., Ghanshani, S., Logsdon, N. J., Rauer, H., Kalman, K., Zhou, J., Beckingham, K., Chandy, K. G., Cahalan, M. D. & Aiyar, J. (1999) J. Biol. Chem. 274, 5746-5754.
5. Lin, C. S., Boltz, R. C., Blake, J. T., Nguyen, M., Talento, A., Fischer, P. A., Springer, M. S., Sigal, N. H., Slaughter, R. S., Garcia, M. L., et al. (1993) J. Exp. Med. 177, 637-645.
6. Ødum, N., Hartzman, R., Jacobsen, B. K., Morling, N., Platz, P., Robbins, F.-M., Ryder, L. P. & Svejgaard, A. (1986) Tissue Antigens 28, 105-118.
7. Ødum, N., Hofmann, B., Jakobsen, B., Langhoff, E., Morling, N., Platz, P., Ryder, L. & Svejgaard, A. (1986) Tissue Antigens 27, 32-43.
8. Nielsen, M.-B., Gerwien, J., Nielsen, M., Geisler, C., Ropke, C., Svejgaard, A. & Ødum, N. (1998) Exp. Clin. Immunogenet. 15, 61-68.
9. Nielsen, M., Ødum, N., Bendtzen, K., Ryder, L. P., Jakobsen, B. K. & Svejgaard, A. (1994) Exp. Clin. Immunogenet. 11, 23-32.
10. Benzaquen, L. R., Brugnara, C., Byers, H. R., Gattoni-Celli, S. & Halperin, J. A. (1995) Nat. Med. 1, 534-540.
11. Pedersen, K. A., Schroøder, R. L., Jensen, B. S., Olesen, S.-P., Strøbæk, D. & Christophersen, P. (1999) Biochim. Biophys. Acta, in press.
12. Grissmer, S., Nguyen, A. N. & Cahalan, M. D. (1993) J. Gen. Physiol. 102, 601-630.