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2+ ions and the hydroxy oxygen atom of the lactate anion in 1 (1.969 and 1.939 Å) clearly support the deprotonation of the OH group.
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77
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32044438648
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note
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2(bdc)(L-lac)(dmf)]), along with a lower ee value (12% in favor of the S enantiomer).
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78
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32044445740
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note
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2(bdc)(L-lac)(dmf)].
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79
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32044474408
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note
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2 for 16 h.
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-
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80
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0026447769
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3CN (10:1). Also see: M. Palucki, P. Hanson, E. N. Jacobsen, Tetrahedron Lett. 1992, 33, 7111-7114.
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Palucki, M.1
Hanson, P.2
Jacobsen, E.N.3
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81
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32044465948
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note
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To better understand the mechanism of the catalytic reaction with 1, we are also investigating the same reaction using an analogous homogeneous catalyst.
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83
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0344845085
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Angew. Chem. Int. Ed. 2003, 42, 5487-5489;
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85
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4644283019
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Angew. Chem. Int. Ed. 2004, 43, 4225-4228.
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