Reductive half-reaction of nitroalkane oxidase: Effect of mutation of the active site aspartate to glutamate

Biochemistry

Volumn 42, Issue 19, 2003, Pages 5850-5856

  Valley, Michael P ^a   Fitzpatrick, Paul F ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; CATALYSIS; CHEMICAL BONDS; KETONES; REDUCTION;

FLAVOENZYMES;

ENZYMES;

ACYL COENZYME A; ASPARTIC ACID; GLUTAMIC ACID; NITROALKANE;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CHEMICAL MODIFICATION; DECOMPOSITION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME SUBSTRATE; MOLECULAR CLONING; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; REACTION ANALYSIS; STEADY STATE;

AMINO ACID SUBSTITUTION; ASPARTIC ACID; CATALYTIC DOMAIN; DIOXYGENASES; FUSARIUM; GLUTAMIC ACID; KINETICS; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; OXYGENASES; THERMODYNAMICS;

EID: 0038613012     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi034061w     Document Type: Article

References (22)

1. Kido, T., Hashizume, K., and Soda, K. (1978) J. Bacteriol. 133, 53-58.
2. Porter, D. J. T., Voet, J. G., and Bright, H. J. (1972) Z. Naturforsch. 27b, 1052-1053.
3. Heasley, C. J., and Fitzpatrick, P. F. (1996) Biochem. Biophys. Res. Commun. 225, 6-10.
4. Gadda, G., and Fitzpatrick, P. F. (1999) Arch. Biochem. Biophys. 363, 309-313.
5. Gadda, G., and Fitzpatrick, P. F. (2000) Biochemistry 39, 1400-1405.
6. Gadda, G., Edmondson, R. D., Russel, D. H., and Fitzpatrick, P. F. (1997) J. Biol. Chem. 272, 5563-5570.
7. Daubner, S. C., Gadda, G., Valley, M. P., and Fitzpatrick, P. F. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 2702-2707.
8. Thorpe, C., and Kim, J. P. (1995) FASEB J. 9, 718-725.
9. Gadda, G., Banerjee, A., and Fitzpatrick, P. F. (2000) Biochemistry 39, 1162-1168.
10. Gadda, G., Banerjee, A., Dangott, L. J., and Fitzpatrick, P. F. (2000) J. Biol. Chem. 275, 31891-31895.
11. Gadda, G., Choe, D. Y., and Fitzpatrick, P. F. (2000) Arch. Biochem. Biophys. 382, 138-144.
12. Gadda, G., and Fitzpatrick, P. F. (1998) Biochemistry 37, 6154-6164.
13. Palmer, G., and Massey, V. (1968) in Biological Oxidation (Singer, T. P., Ed.) pp 263-300, John Wiley and Sons, New York.
14. Bright, H. J., and Porter, D. J. T. (1975) in The Enzymes (Boyer, P., Ed.) 3rd ed., Vol. XII, pp 421-505, Academic Press, New York.
15. Emanuele, J. J., Jr., and Fitzpatrick, P. F. (1995) Biochemistry 34, 3710-3715.
16. Porter, D. J. T., Voet, J. G., and Bright, H. J. (1977) J. Biol. Chem. 252, 4464-4473.
17. Weibel, M. K., and Bright, H. J. (1971) J. Biol. Chem. 246, 2734-2744.
18. Gadda, G., and Fitzpatrick, P. F. (2000) Biochemistry 39, 1406-1410.
19. Strickland, S., Palmer, G., and Massey, V. (1975) J. Biol. Chem. 250, 4048-4052.
20. Raines, R. T., Sutton, E. L., Straus, D. R., Gilbert, W., and Knowles, J. R. (1986) Biochemistry 25, 7142-7154.
21. Battaile, K. P., Mohsen, A. A., and Vockley, J. (1996) Biochemistry 35, 15356-15363.
22. Peterson, K. L., Galitz, D. S., and Srivastava, D. K. (1998) Biochemistry 37, 1697-1705.