Iontophoresis: A non-invasive ocular drug delivery

Journal of Controlled Release

Volumn 110, Issue 3, 2006, Pages 479-489

  Eljarrat Binstock, Esther ^a   Domb, Abraham J ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Eye; Hydrogel; Iontophoresis; Ocular delivery

Indexed keywords

BIOMEDICAL EQUIPMENT; DRUG PRODUCTS; NONINVASIVE MEDICAL PROCEDURES; OPHTHALMOLOGY; PHARMACOKINETICS; TOXICITY;

IONTOPHORESIS; OCULAR DRUG DELIVERY; OCULAR IONTOPHORETIC DEVICE;

CONTROLLED DRUG DELIVERY;

ACETYLSALICYLIC ACID; AMIKACIN; CARBOPLATIN; CEFAZOLIN; CIPROFLOXACIN; DEXAMETHASONE; DICLOFENAC; FLUOROURACIL; FOSCARNET; GENTAMICIN; KETOCONAZOLE; METHYLPREDNISOLONE; OLIGONUCLEOTIDE; TICARCILLIN; TOBRAMYCIN; VANCOMYCIN; VIDARABINE;

BURN; CORNEA; DEVICE; DRUG DELIVERY SYSTEM; DRUG RETENTION; EDEMA; ELECTRIC CURRENT; ELECTRODE; HUMAN; HYDROGEL; IN VITRO STUDY; INFLAMMATION; IONTOPHORESIS; NON INVASIVE PROCEDURE; NONHUMAN; PRIORITY JOURNAL; RABBIT; REVIEW; VISUAL SYSTEM;

ADMINISTRATION, TOPICAL; ANIMALS; DRUG DELIVERY SYSTEMS; EYE; EYE DISEASES; HUMANS; IONTOPHORESIS;

EID: 31544465937     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.09.049     Document Type: Review

References (64)

1. V. Baeyens, C. Percicot, and M. Zignani Ocular drug delivery in veterinary medicine Advanced Drug Delivery Reviews 28 3 1997 335 361
2. R. Wirtz Die ionentherapie in der augenheilkunde Klinische Monatsblätter für Augenheilkunde 46 1908 543 579
3. M.E. Myles, J.M. Loutsch, and S. Higaki Ocular iontophoresis A.K. Mitra Ophthalmic Drug Delivery Systems vol. 130 2003 Marcel Dekker, Inc. New York 365 408
4. R.H. Guy, Y.N. Kalia, and M.B. Delgado-Charro Iontophoresis: electrorepulsion and electroosmosis Journal of Controlled Release 64 2000 129 132
5. R. Burnette, and D. Marrero Comparison between the iontophoretic and passive transport of thyrotropin releasing hormone across excised nude mouse skin Journal of Pharmaceutical Sciences 75 1986 738 743
6. L. Gangarosa, N. Park, and C. Wiggins Increased penetration of non-electrolytes into mouse skin during iontophoretic water transport (iontohydrokinesis) Journal of Pharmacology and Experimental Therapeutics 212 1980 377 381
7. G.B. Kasting Theoretical models for iontophoretic delivery Advanced Drug Delivery Reviews 9 1992 177 199
8. M.J. Pikal The role of electroosmotic flow in transdermal iontophoresis Advanced Drug Delivery Reviews 46 1-3 2001 281 305
9. Y.N. Kalia, A. Naik, and J. Garrison Iontophoretic drug delivery Advanced Drug Delivery Reviews 56 5 2004 619 658
10. T. Asahara, K. Shinomiya, and T. Naito Induction of gene into the rabbit eye by iontophoresis: preliminary report Japanese Journal of Ophthalmology 45 1 2001 31 39
11. F.F. Behar-Cohen, J.M. Parel, and Y. Pouliquen Iontophoresis of dexamethasone in the treatment of endotoxin-induced-uveitis in rats Experimental Eye Research 65 1997 533 545
12. D. Sarraf, and D.A. Lee The role of iontophoresis in ocular drug-delivery Journal of Ocular Pharmacology 10 1 1994 69 81
13. T.T. Lam, D.P. Edward, and X.A. Zhu Transscleral iontophoresis of dexamethasone Archives of Ophthalmology 107 9 1989 1368 1371
14. M. Barza Transscleral iontophoresis of cefazolin, cicarcillin, and gentamicin in the rabbit Ophthalmology 93 1986 133 139
15. F.F. Behar-Cohen, A. El Aouni, and S. Gautier Transscleral Coulomb-controlled iontophoresis of methyl prednisolone into the rabbit eye: Influence of duration of treatment, current intensity and drug concentration on ocular tissue and fluid levels Experimental Eye Research 74 1 2002 51 59
16. B.C. Hayden, M.E. Jockovich, and T.G. Murray Pharmacokinetics of systemic versus focal carboplatin chemotherapy in the rabbit eye: possible implication in the treatment of retinoblastoma Investigative Ophthalmology & Visual Science 45 2004 3644 3649
17. M. Voigt, M. Kralinger, and G. Kieselbach Ocular aspirin distribution: a comparison of intravenous, topical, and coulomb-controlled iontophoresis administration Investigative Ophthalmology & Visual Science 43 10 2002 3299 3306
18. R.F. Jones, and D.M. Maurice New methods of measuring the rate of aqueous flow in man with fluorescein Experimental Eye Research 5 1966 208 220
19. R. Grossman, D.F. Chu, and D.A. Lee Regional ocular gentamicin levels after transcorneal and transscleral iontophoresis Investigative Ophthalmology & Visual Science 31 1990 909 916
20. J. Frucht-Pery, D. Goren, and A. Solomon The distribution of gentamicin in the rabbit cornea following iontophoresis to the central cornea Journal of Ocular Pharmacology and Therapeutics 15 3 1999 251 256
21. J. Frucht-Pery, A. Solomon, and R. Doron Efficacy of iontophoresis in the rat cornea Graefe's Archive for Clinical and Experimental Ophthalmology 234 1996 765 769
22. G.A. Fischer, T.M. Parkinson, and M.A. Szlek OcuPhor-the future of ocular drug delivery Drug Delivery Technology 2 2002 50 52
23. T.M. Parkinson, E. Ferguson, and S. Febbraro Tolerance of ocular iontophoresis in healthy volunteers Journal of Ocular Pharmacology and Therapeutics 19 2 2003 145 151
24. T.M. Parkinson, D.J. Miller, and L.B. Lloyd The effects of in vivo iontophoresis on rabbit eye structure and retinal function Investigative Ophthalmology & Visual Science 41 2000 S772
25. D.L. Vollmer, M.A. Szlek, and K. Kolb In vivo transscleral iontophores is of amikacin to rabbit eyes Journal of Ocular Pharmacology and Therapeutics 18 6 2002 549 558
26. M.S. Hastings, S.K. Li, and D.J. Miller Visulex: advancing iontophoresis for effective noninvasive back-to-the-eye therapeutics Drug Delivery Technology 4 3 2004 53 57
27. E. Eljarrat-Binstock, F. Raiskup, and J. Frucht-Pery Transcorneal and transscleral iontophoresis of dexamethasone phosphate in rabbits using drug loaded hydrogel Journal of Controlled Release 106 3 2005 386 390
28. E. Eljarrat-Binstock, F. Raiskup, and J. Frucht-Pery Hydrogel probe for iontophoresis drug delivery to the eye Journal of Biomaterials Science. Polymer Ed. 15 4 2004 397 413
29. E. Eljarrat-Binstock, F. Raiskup, and D. Stepensky Delivery of gentamicin to the rabbit eye by drug-loaded hydrogel iontophoresis Investigative Ophthalmology & Visual Science 45 8 2004 2543 2548
30. J. Frucht-Pery, H. Mechoulam, and C.S. Siganos Iontophoresis-gentamicin delivery into the rabbit cornea, using a hydrogel delivery probe Experimental Eye Research 78 3 2004 745 749
31. F. Brouneus, K. Karami, and P. Beronius Diffusive transport properties of some local anesthetics applicable for iontophoretic formulation of the drugs International Journal of Pharmaceutics 218 1-2 2001 57 62
32. C.R. Anderson, R.L. Morris, and S.D. Boeh Effects of iontophoresis current magnitude and duration on dexamethasone deposition and localized drug retention Physical Therapy 83 2 2003 161 170
33. S.S. Kamath, and L.P. Gangarosa Electrophoretic evaluation of the mobility of drugs suitable for iontophoresis Methods and Findings in Experimental and Clinical Pharmacology 17 4 1995 227 232
34. D. Monti, L. Saccomani, and P. Chetoni Effect of iontophoresis on transcorneal permeation 'in vitro' of two beta-blocking agents, and on corneal hydration International Journal of Pharmaceutics 250 2 2003 423 429
35. 2 esters across cornea in vitro International Journal of Pharmaceutics 29 1986 259 266
36. P.H. Fishman, W.M. Jay, and J.P. Rissing Iontophoresis of gentamicin into aphasic rabbit eyes Investigative Ophthalmology & Visual Science 25 1984 343 345
37. T.B. Choi, and D.A. Lee Transscleral and transcorneal iontophoresis of vancomycin in rabbit eyes Journal of Ocular Pharmacology 4 2 1988 153 164
38. D.S. Rootman, J.A. Jantzen, and J.R. Gonzalez Pharmacokinetics and safety of transcorneal iontophoresis of tobramycin in the rabbit Investigative Ophthalmology & Visual Science 29 9 1988 1397 1401
39. J. Frucht-Pery, F. Raiskup, H. Mechoulam, et al., Iontophoretic treatment of experimental pseudomonas keratitis in rabbit eye using gentamicin-loaded hydrogel, (submitted for publication).
40. J.A. Hobden, R.J. Ocallaghan, and J.M. Hill Tobramycin iontophoresis into corneas infected with drug-resistant pseudomonas-aeruginosa Current Eye Research 8 11 1989 1163 1169
41. J.A. Hobden, J.J. Reidy, and R.J. Ocallaghan Ciprofloxacin iontophoresis for aminoglycoside-resistant pseudomonal keratitis Investigative Ophthalmology & Visual Science 31 10 1990 1940 1944
42. D.S. Rootman, J.A. Hobden, and J.A. Jantzen Iontophoresis of tobramycin for the treatment of experimental pseudomonas keratitis in the rabbit Archives of Ophthalmology 106 2 1988 262 265
43. M. Berdugo, F. Valamanesh, and C. Andrieu Delivery of antisense oligonucleotide to the cornea by iontophoresis Antisense & Nucleic Acid Drug Development 13 2 2003 107 114
44. D.H. Geroski, and H.F. Edelhauser Transscleral drug delivery for posterior segment disease Advanced Drug Delivery Reviews 52 1 2001 37 48
45. M. Barza, C. Peckman, and J. Baum Transscleral iontophoresis as an adjunctive treatment for experimental endophthalmitis Archives of Ophthalmology 105 10 1987 1418 1420
46. P. Chapon, M. Voigt, and S. Gautier Intraocular tissues pharmacokinetics of ganciclovir transscleral Coulomb controlled iontophoresis in rabbits Investigative Ophthalmology & Visual Science 40 4 1999 S189
47. T.T. Lam, J. Fu, and R. Chu Intravitreal delivery of ganciclovir in rabbits by transscleral iontophoresis Journal of Ocular Pharmacology 10 3 1994 571 575
48. M.T. Kralinger, M. Voigt, and G.F. Kieselbach Ocular delivery of acetylsalicylic acid by repetitive Coulomb-controlled iontophoresis Ophthalmic Research 35 2 2003 102 110
49. D. Sarraf, R.A. Equi, and G.N. Holland Transscleral iontophoresis of foscarnet American Journal of Ophthalmology 115 6 1993 748 754
50. D. Chauvaud, F.F. Behar-Cohen, and J.M. Parel Transscleral Iontophoresis of cortcicosteoids: Phase II clinical trial Investigative Ophthalmology & Visual Science 41 4 2000 S79
51. M. Halhal, G. Renard, and R.A. Bejjani Corneal graft rejection and corticoid iontophoresis: 3 case reports Journal Français D'Ophtalmologie 26 4 2003 391 395
52. F.F. Behar-Cohen, M. Halhal, and D. BenEzra Reversal of corneal graft rejection by iontophoresis of methylprednisolone Investigative Ophthalmology & Visual Science 43 2002 U504
53. M. Halhal, G. Renard, and Y. Courtois Iontophoresis: from the lab to the bed side Experimental Eye Research 78 3 2004 751 757
54. J. Horwath-Winter, O. Schmut, and E.M. Haller-Schober Iodide iontophoresis as a treatment for dry eye syndrome British Journal of Ophthalmology 89 1 2005 40 44
55. J.M. Hill, N. Park, and L.P. Gangarosa Iontophoresis of vidarabine monophosphate into rabbit eyes. Investigative Ophthalmology & Visual Science 17 1978 473 476
56. L. Hughes, and D.M. Maurice A fresh look at iontophoresis Archives of Ophthalmology 102 1984 1825 1829
57. R. Grossman, and D.A. Lee Transscleral and transcorneal iontophoresis of ketoconazole in the rabbit eye Ophthalmology 96 5 1989 724 729
58. D.M. Maurice Iontophoresis of fluorescein into the posterior segment of the rabbit eye Ophthalmology 93 1 1986 128 132
59. M. Barza, C. Peckman, and J. Baum Transscleral iontophoresis of gentamicin in monkeys Investigative Ophthalmology & Visual Science 28 6 1987 1033 1036
60. T.T. Lam, J. Fu, and M.O.M. Tso A histopathologic study of retinal lesions inflicted by transscleral iontophoresis Graefe's Archive for Clinical and Experimental Ophthalmology 229 4 1991 389 394
61. N.L. Burstein, I.H. Leopold, and D.B. Bernacchi Trans-scleral iontophoresis of gentamicin Journal of Ocular Pharmacology 1 1985 363 368
62. M.O. Yoshizumi, D. Cohen, and I. Verbukh Experimental transscleral iontophoresis of ciprofloxacin Journal of Ocular Pharmacology 7 2 1991 163 167
63. M.O. Yoshizumi, J.A. Roca, and D.A. Lee Ocular lontophoretic supplementation of intravenous foscarnet therapy American Journal of Ophthalmology 122 1 1996 86 90
64. M. Kondo, and M. Araie Iontophoresis of 5-fluorouracil into the conjunctiva and sclera Investigative Ophthalmology & Visual Science 30 3 1989 583 585