-
1
-
-
0029849620
-
Cancer cell cycles
-
Washington DC
-
Sherr, C. J. Cancer cell cycles. Science (Washington DC), 274: 1672-1677, 1996.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
3
-
-
0028982932
-
INK4A transcript
-
INK4A transcript. Cancer Res., 55: 2995-2997, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 2995-2997
-
-
Mao, L.1
Merlo, A.2
Bedi, G.3
Shapiro, G.I.4
Edwardsn, C.D.5
Rollins, B.J.6
Sidransky, D.7
-
4
-
-
0029060657
-
Complex structure and regulation of the p16 (MTS1) locus
-
Stone, S., Jiang, P., Dayananth., P., Tavtigian, S. V., Katcher, H., Parry, D., Peters, G., and Kamb, A. Complex structure and regulation of the p16 (MTS1) locus. Cancer Res., 55: 2988-2994, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 2988-2994
-
-
Stone, S.1
Jiang, P.2
Dayananth, P.3
Tavtigian, S.V.4
Katcher, H.5
Parry, D.6
Peters, G.7
Kamb, A.8
-
5
-
-
0029587551
-
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
-
Quelle, D. E., Zindy, F., Ashmun, R. A., and Sherr, C. J. Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest. Cell, 83: 993-100, 1995.
-
(1995)
Cell
, vol.83
, pp. 993-1100
-
-
Quelle, D.E.1
Zindy, F.2
Ashmun, R.A.3
Sherr, C.J.4
-
6
-
-
0031297713
-
INK4A/MTS1/CDKN2 locus to human malignancies
-
Meijer L., Guidet S., and Philipp M. (eds.), New York: Plenum Press
-
INK4A/MTS1/CDKN2 locus to human malignancies. In: Meijer L., Guidet S., and Philipp M. (eds.), Progress in Cell Cycle Research, Vol. 3, pp. 109-124. New York: Plenum Press, 1997.
-
(1997)
Progress in Cell Cycle Research
, vol.3
, pp. 109-124
-
-
Larsen, C.J.1
-
7
-
-
9544251503
-
p16 and p16β are potent growth suppressors of head and neck squamous carcinoma cells in vitro
-
Liggett, W. H., Sewell, D. A., Rocco, J., Ahrendt, S. A., Koch, W., and Sidransky, D. p16 and p16β are potent growth suppressors of head and neck squamous carcinoma cells in vitro. Cancer Res., 56: 4119-4123, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 4119-4123
-
-
Liggett, W.H.1
Sewell, D.A.2
Rocco, J.3
Ahrendt, S.A.4
Koch, W.5
Sidransky, D.6
-
8
-
-
0029658666
-
Loss of the p16INK4a and p15INK4b genes, as well as neighboring 9p21 markers, in sporadic melanoma
-
Flores, J. F., Walker, G. J., Glendening, J. M., Haluska, F. G., Castresana, J. S., Rubio, M-P., Pastorfide, G. C., Boyer, L. A., Kao, W. H., Bulyk, M., Barnhill, R. L., Hayward, N. K., Housman, D. E., and Fountain, J. W. Loss of the p16INK4a and p15INK4b genes, as well as neighboring 9p21 markers, in sporadic melanoma. Cancer Res., 56: 5023-5032, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 5023-5032
-
-
Flores, J.F.1
Walker, G.J.2
Glendening, J.M.3
Haluska, F.G.4
Castresana, J.S.5
Rubio, M.-P.6
Pastorfide, G.C.7
Boyer, L.A.8
Kao, W.H.9
Bulyk, M.10
Barnhill, R.L.11
Hayward, N.K.12
Housman, D.E.13
Fountain, J.W.14
-
9
-
-
0029921317
-
Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer
-
Halls, M., and Peters, G. Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer. Adv. Cancer Res., 68: 67-108, 1996.
-
(1996)
Adv. Cancer Res.
, vol.68
, pp. 67-108
-
-
Halls, M.1
Peters, G.2
-
10
-
-
0028121279
-
A cell cycle regulator potentially involved in genesis of many tumor types
-
Washington DC
-
Kamb, A., Gruis, N. A., Weaver-Feldhaus, J., Liu, J., Harshman, K., Tavtigian, S. V., Stocjert, E., Day, R. S., Johnson, B. E., and Skolnick, M. H. A cell cycle regulator potentially involved in genesis of many tumor types. Science (Washington DC), 264: 436-440, 1994.
-
(1994)
Science
, vol.264
, pp. 436-440
-
-
Kamb, A.1
Gruis, N.A.2
Weaver-Feldhaus, J.3
Liu, J.4
Harshman, K.5
Tavtigian, S.V.6
Stocjert, E.7
Day, R.S.8
Johnson, B.E.9
Skolnick, M.H.10
-
11
-
-
0028275733
-
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
-
Nobori, T., Miura, K., Wu, D. J., Lois, A., Takabayashi, K., and Carson, D. A. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature (Lond.), 368: 753-756, 1994.
-
(1994)
Nature (Lond.)
, vol.368
, pp. 753-756
-
-
Nobori, T.1
Miura, K.2
Wu, D.J.3
Lois, A.4
Takabayashi, K.5
Carson, D.A.6
-
12
-
-
0029091503
-
Frequency of homozygous deletion at p16/CDKN2 in primary human tumors
-
Cairns, P., Polascik, T. J., Eby, Y., Tokino, K., Califano, J., Merlo, A., Mao, L., Herath, J., Jenkins, R., Westra, W., Rutter, J. L., Buckler, A., Gabrielson, E., Tockman, M., Cho, K. R., Hedrick, L., Bova, G. S., Isaacs, W., Koch, W., Schwab, D., and Sidransky, D. Frequency of homozygous deletion at p16/CDKN2 in primary human tumors. Nat. Genet., 11: 210-212, 1995.
-
(1995)
Nat. Genet.
, vol.11
, pp. 210-212
-
-
Cairns, P.1
Polascik, T.J.2
Eby, Y.3
Tokino, K.4
Califano, J.5
Merlo, A.6
Mao, L.7
Herath, J.8
Jenkins, R.9
Westra, W.10
Rutter, J.L.11
Buckler, A.12
Gabrielson, E.13
Tockman, M.14
Cho, K.R.15
Hedrick, L.16
Bova, G.S.17
Isaacs, W.18
Koch, W.19
Schwab, D.20
Sidransky, D.21
more..
-
13
-
-
0027938776
-
Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemias
-
Hebert, J., Cayuela, J. M., Berkeley, J., and Sigaux, F. Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T-but not from B-cell lineage acute lymphoblastic leukemias. Blood, 84: 4038-4044, 1994.
-
(1994)
Blood
, vol.84
, pp. 4038-4044
-
-
Hebert, J.1
Cayuela, J.M.2
Berkeley, J.3
Sigaux, F.4
-
14
-
-
0028899626
-
Homozygous MTS1 (p16INK4A) deletion in primary tumor cells of 163 leukemic patients
-
Cayuela, J. M., Hebert, J., and Sigaux, F. Homozygous MTS1 (p16INK4A) deletion in primary tumor cells of 163 leukemic patients. Blood, 85: 854, 1995.
-
(1995)
Blood
, vol.85
, pp. 854
-
-
Cayuela, J.M.1
Hebert, J.2
Sigaux, F.3
-
15
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo, A., Herman, J. G., Mao, L., Lee, D. J., Gabrielson, E., Burger, P. C., Baylin, S. B., and Sidransky, D. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med., 1: 686-692, 1995.
-
(1995)
Nat. Med.
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
16
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman, J. G., Merlo, A., Mao, L., Lapidus, R. G., Issa, J. P. J., Davidson, N. E., Sidransky, D., and Baylin, S. B. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res., 55: 4525-4530, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
Lapidus, R.G.4
Issa, J.P.J.5
Davidson, N.E.6
Sidransky, D.7
Baylin, S.B.8
-
17
-
-
0028875205
-
Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
-
Gonzales-Zulueta, M., Bender, C. M., Yang, A. S., Nguyen, T., Beart, R. W., Van Turnout, J. M., and Jones, P. A. Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res., 55: 4531-4535, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4531-4535
-
-
Gonzales-Zulueta, M.1
Bender, C.M.2
Yang, A.S.3
Nguyen, T.4
Beart, R.W.5
Van Turnout, J.M.6
Jones, P.A.7
-
18
-
-
0030612751
-
INK4a and p16β transcripts in B-lymphoblastoid cells from members of hereditary melanoma families without CDKN2 exon mutations
-
INK4a and p16β transcripts in B-lymphoblastoid cells from members of hereditary melanoma families without CDKN2 exon mutations. Oncogene, 15: 515-523, 1997.
-
(1997)
Oncogene
, vol.15
, pp. 515-523
-
-
Rizos, H.1
Becker, T.M.2
Holland, E.A.3
Kefford, R.F.4
Graham, J.M.5
-
20
-
-
0030728468
-
ARF
-
ARF. Cell. 91: 649-659, 1997.
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
21
-
-
9444276546
-
Prevalence of germ-line mutations in p16. p19ARF, and CDK4 in familial melanoma: Analysis of a clinic-based population
-
Fitzgerald, M. G., Harkin, D. P., Silva-Arrieta, S., Macdonald, D. J., Lucchina, L. C., Unsal, H., O'Neill, E., Koh, J., Finkelstein, D. M., Isselbacher, K. J., Sober, A. J., and Haber, D. A. Prevalence of germ-line mutations in p16. p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population. Proc. Natl. Acad. Sci. USA, 93: 8541-8545, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 8541-8545
-
-
Fitzgerald, M.G.1
Harkin, D.P.2
Silva-Arrieta, S.3
Macdonald, D.J.4
Lucchina, L.C.5
Unsal, H.6
O'Neill, E.7
Koh, J.8
Finkelstein, D.M.9
Isselbacher, K.J.10
Sober, A.J.11
Haber, D.A.12
-
22
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Zhang, Y., Xiong, Y., and Yarbrough, W. G. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell, 92: 725-734, 1998.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
23
-
-
0032549704
-
ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell, 92: 713-723, 1998.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liégeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon-Cardo, C.11
DePinho, R.A.12
-
24
-
-
0001163006
-
Molecular biology of lung cancer
-
V. T. DeVila, S. Hellman, and S. A. Rosenberg (eds.), Philadelphia: Lippincott
-
Minna, J. D., Sekido, Y., Fong, K., and Gazdar, A. F. Molecular biology of lung cancer. In: V. T. DeVila, S. Hellman, and S. A. Rosenberg (eds.), Cancer: Principles and Practice of Oncology, pp. 849-857. Philadelphia: Lippincott, 1997.
-
(1997)
Cancer: Principles and Practice of Oncology
, pp. 849-857
-
-
Minna, J.D.1
Sekido, Y.2
Fong, K.3
Gazdar, A.F.4
-
25
-
-
0032576630
-
Mechanisms of p16INK4A inactivation in non small cell lung cancer
-
Gazzeri, S., Gouyer, V., Vourc'h, C. Brambilla, C., and Brambilla, E. Mechanisms of p16INK4A inactivation in non small cell lung cancer. Oncogene. 16: 497-505, 1998.
-
(1998)
Oncogene
, vol.16
, pp. 497-505
-
-
Gazzeri, S.1
Gouyer, V.2
Vourc'h, C.3
Brambilla, C.4
Brambilla, E.5
-
26
-
-
0026787741
-
Basal cell (basaloid) carcinoma of the lung
-
Brambilla, E., Moro, D., Veale, D., Brichon, P. Y., Stoebner, P., Paramelle, B., and Brambilla, C. Basal cell (basaloid) carcinoma of the lung. Hum. Pathol., 23: 993-1003, 1992.
-
(1992)
Hum. Pathol.
, vol.23
, pp. 993-1003
-
-
Brambilla, E.1
Moro, D.2
Veale, D.3
Brichon, P.Y.4
Stoebner, P.5
Paramelle, B.6
Brambilla, C.7
-
27
-
-
0025768416
-
Neuroendocrine lumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma
-
Travis, W. D., Linnoila, R. I., Tsokos, M. G., Hitchkock, C. L., Cutler, G. B., Nieman, L., Chrousos, G., Pass, H., and Doppman, J. Neuroendocrine lumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma. Am. J. Surg. Pathol., 15: 529-553, 1991.
-
(1991)
Am. J. Surg. Pathol.
, vol.15
, pp. 529-553
-
-
Travis, W.D.1
Linnoila, R.I.2
Tsokos, M.G.3
Hitchkock, C.L.4
Cutler, G.B.5
Nieman, L.6
Chrousos, G.7
Pass, H.8
Doppman, J.9
-
29
-
-
0002948749
-
Mechanism of retinoblastoma gene inactivation in the spectrum of neuroendocrine lung tumors
-
Gouyer, V., Gazzeri, S., Bolon, I., Drevet, C., Brambilla, C., and Brambilla, E. Mechanism of retinoblastoma gene inactivation in the spectrum of neuroendocrine lung tumors. Am. J. Respir. Cell Mol. Biol., 17: 1-9, 1997.
-
(1997)
Am. J. Respir. Cell Mol. Biol.
, vol.17
, pp. 1-9
-
-
Gouyer, V.1
Gazzeri, S.2
Bolon, I.3
Drevet, C.4
Brambilla, C.5
Brambilla, E.6
-
30
-
-
0030025518
-
Compilation of somatic mutations of the CDKN2 gene in human cancers: Non-random distribution of base substitution
-
Pollock, P., Pearson, J. V., and Hayward. N. K. Compilation of somatic mutations of the CDKN2 gene in human cancers: non-random distribution of base substitution. Genes Chromosomes Cancer, 15: 77-88, 1996.
-
(1996)
Genes Chromosomes Cancer
, vol.15
, pp. 77-88
-
-
Pollock, P.1
Pearson, J.V.2
Hayward, N.K.3
-
31
-
-
0027717341
-
Immunohistochemical study of p53 in human lung carcinoma
-
Brambilla, E., Gazzeri, S., Moro, D., Caron De Fromentel, C., Gouyer, V., Jacrot, M., and Brambilla, C. Immunohistochemical study of p53 in human lung carcinoma. Am. J. Pathol., 143: 199-210, 1993.
-
(1993)
Am. J. Pathol.
, vol.143
, pp. 199-210
-
-
Brambilla, E.1
Gazzeri, S.2
Moro, D.3
Caron De Fromentel, C.4
Gouyer, V.5
Jacrot, M.6
Brambilla, C.7
-
32
-
-
0029052951
-
Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition
-
Koh, J., Enders, G. H., Dynlacht, B. D., and Harlow, E. Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition. Nature (Lond.), 375: 506-510, 1995.
-
(1995)
Nature (Lond.)
, vol.375
, pp. 506-510
-
-
Koh, J.1
Enders, G.H.2
Dynlacht, B.D.3
Harlow, E.4
-
33
-
-
0028236395
-
p53 genetic abnormalities and myc activation in human lung carcinoma
-
Gazzeri, S., Brambilla, E., Caron De Fromentel, C., Gouyer, V., Moro, D., Perron, P., Berger, F., and Brambilla, C. p53 genetic abnormalities and myc activation in human lung carcinoma. Int. J. Cancer, 58: 24-32, 1994.
-
(1994)
Int. J. Cancer
, vol.58
, pp. 24-32
-
-
Gazzeri, S.1
Brambilla, E.2
Caron De Fromentel, C.3
Gouyer, V.4
Moro, D.5
Perron, P.6
Berger, F.7
Brambilla, C.8
-
34
-
-
0026068396
-
The p53 gene is very frequently mutated in small-cell lung cancer with a distinct nucleotide substitution pattern
-
Takahashi, T., Takahashi, T., Suzuki, H., Hida, T., Sekido, Y., Ariyoshi, Y., and Ueda, R. The p53 gene is very frequently mutated in small-cell lung cancer with a distinct nucleotide substitution pattern. Oncogene, 6: 1775-1778, 1991.
-
(1991)
Oncogene
, vol.6
, pp. 1775-1778
-
-
Takahashi, T.1
Takahashi, T.2
Suzuki, H.3
Hida, T.4
Sekido, Y.5
Ariyoshi, Y.6
Ueda, R.7
-
35
-
-
0026508613
-
High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors
-
D'Amico, D., Carbone, D., Mitsudomi, T., Nau, M., Fedorko, J., Russel, E., Johnson, B., Buchhagen, D., Bodner, S., Phelps, R., Gazdar, A., and Minna, J. D. High frequency of somatically acquired p53 mutations in small-cell lung cancer cell lines and tumors. Oncogene, 7: 339-346, 1992.
-
(1992)
Oncogene
, vol.7
, pp. 339-346
-
-
D'Amico, D.1
Carbone, D.2
Mitsudomi, T.3
Nau, M.4
Fedorko, J.5
Russel, E.6
Johnson, B.7
Buchhagen, D.8
Bodner, S.9
Phelps, R.10
Gazdar, A.11
Minna, J.D.12
-
36
-
-
0032080297
-
The human oncoprotein MDM2 arrests the cell cycle: Elimination of its cell-cycle-inhibitory function induces tumorigenesis
-
Brown, D. R., Thomas, C. A., and Deb, S. P. The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis. EMBO J., 17: 2513-2525, 1998.
-
(1998)
EMBO J.
, vol.17
, pp. 2513-2525
-
-
Brown, D.R.1
Thomas, C.A.2
Deb, S.P.3
-
37
-
-
0029028353
-
Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein
-
Martin, K., Trouche, D., Hagemeier, C., Sorensen, T. S., La Thangue, N. B., and Kouzarides, T. Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein. Nature (Lond.), 375: 691-694, 1995.
-
(1995)
Nature (Lond.)
, vol.375
, pp. 691-694
-
-
Martin, K.1
Trouche, D.2
Hagemeier, C.3
Sorensen, T.S.4
La Thangue, N.B.5
Kouzarides, T.6
-
38
-
-
0029028354
-
Interaction between the retinoblastoma protein and the oncoprotein MDM2
-
Xiao, Z. X., Chen, J., Levine, A. J., Modjtahedi, N., Xing, J., Sellers, W. R., and Livingston, D. M. Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature (Lond.), 375: 694-698, 1995.
-
(1995)
Nature (Lond.)
, vol.375
, pp. 694-698
-
-
Xiao, Z.X.1
Chen, J.2
Levine, A.J.3
Modjtahedi, N.4
Xing, J.5
Sellers, W.R.6
Livingston, D.M.7
|