-
1
-
-
0032549704
-
ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell, 92: 713-723, 1998.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.-W.10
Cordon-Cardo, C.11
DePinho, R.A.12
-
2
-
-
0027769876
-
A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK 4
-
Serrano, M., Hannon, G. J., and Beach, D. A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK 4. Nature (Lond.), 366: 704-707, 1993.
-
(1993)
Nature (Lond.)
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
3
-
-
0029033861
-
The retinoblastoma protein and cell cycle control
-
Weinberg, R. A. The retinoblastoma protein and cell cycle control. Cell, 81: 323-330, 1995.
-
(1995)
Cell
, vol.81
, pp. 323-330
-
-
Weinberg, R.A.1
-
4
-
-
0030728468
-
ARF
-
ARF. Cell, 91: 649-659, 1997.
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
5
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Zhang, Y., Xiong, Y., and Yarbrough, W. G. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell, 92: 725-734, 1998.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
7
-
-
0029888514
-
Biological and clinical importance of the p53 tumor suppressor gene
-
Velculescu, V. E., and El-Deiry, W. S. Biological and clinical importance of the p53 tumor suppressor gene. Clin. Chem., 42: 858-868, 1996.
-
(1996)
Clin. Chem.
, vol.42
, pp. 858-868
-
-
Velculescu, V.E.1
El-Deiry, W.S.2
-
8
-
-
0030965946
-
Regulation of p53 stability by Mdm2
-
Kubbutat, M. H., Jones, S. N., and Vousden, K. H. Regulation of p53 stability by Mdm2. Nature (Lond.), 387: 299-303, 1997.
-
(1997)
Nature (Lond.)
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.1
Jones, S.N.2
Vousden, K.H.3
-
9
-
-
0027222956
-
Mapping of the p53 and mdm-2 interaction domains
-
Chen, J., Marechal, V., and Levine, A. J. Mapping of the p53 and mdm-2 interaction domains. Mol. Cell. Biol., 13: 4107-4114, 1993.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 4107-4114
-
-
Chen, J.1
Marechal, V.2
Levine, A.J.3
-
10
-
-
0027244853
-
The p53-mdm-2 autoregulatory feedback loop
-
Wu, X., Bayle, J. H., Olson, D., and Levine, A. J. The p53-mdm-2 autoregulatory feedback loop. Genes Dev., 7: 1126-1132, 1993.
-
(1993)
Genes Dev.
, vol.7
, pp. 1126-1132
-
-
Wu, X.1
Bayle, J.H.2
Olson, D.3
Levine, A.J.4
-
11
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo, A., Herman, J. G., Mao, L., Lee, D. J., Gabrielson, E., Burger, P. C., Baylin, S. B., and Sidransky, D. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat. Med., 1: 686-692, 1995.
-
(1995)
Nat. Med.
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
12
-
-
0029554989
-
The spectrum of mutations at the p53 locus
-
Levine, A. J., Wu, M. C., Chang, A., Silver, A., Attiyeh, E. F., Lin, J., and Epstein, C. B. The spectrum of mutations at the p53 locus. Ann. NY Acad. Sci., 768: 111-128, 1995.
-
(1995)
Ann. NY Acad. Sci.
, vol.768
, pp. 111-128
-
-
Levine, A.J.1
Wu, M.C.2
Chang, A.3
Silver, A.4
Attiyeh, E.F.5
Lin, J.6
Epstein, C.B.7
-
13
-
-
0019960812
-
A point mutation is responsible for the aquisition of transforming properties by the T24 human bladder carcinoma oncogene
-
Reddy, E. P., Reynolds, R. K., Santos, E., and Barbacid, M. A point mutation is responsible for the aquisition of transforming properties by the T24 human bladder carcinoma oncogene. Nature (Lond.), 300: 149-152, 1982.
-
(1982)
Nature (Lond.)
, vol.300
, pp. 149-152
-
-
Reddy, E.P.1
Reynolds, R.K.2
Santos, E.3
Barbacid, M.4
-
14
-
-
0026446686
-
Identification of a minimal transforming domain of p53: Negative dominance through abrogation of sequence-specific DNA binding
-
Shaulian, E., Zauberman, A., Ginsberg, D., and Oren, M. Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding. Mol. Cell. Biol., 12: 5581-5592, 1992.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 5581-5592
-
-
Shaulian, E.1
Zauberman, A.2
Ginsberg, D.3
Oren, M.4
-
15
-
-
0027410585
-
The transforming and suppressor functions of p53 alleles: Effects of mutations that disrupt phosphorylation, oligomerization and nuclear translocation
-
Slingerland, J. M., Jenkins, J. R., and Benchimol, S. The transforming and suppressor functions of p53 alleles: effects of mutations that disrupt phosphorylation, oligomerization and nuclear translocation. EMBO J., 12: 1029-1037, 1993.
-
(1993)
EMBO J.
, vol.12
, pp. 1029-1037
-
-
Slingerland, J.M.1
Jenkins, J.R.2
Benchimol, S.3
-
16
-
-
0025739379
-
Simplified mammalian DNA isolation procedure
-
Laird, P. W., Zijderveld, A., Linders, K., Rudnicki, M. A., Jaenisch, R., and Berns, A. Simplified mammalian DNA isolation procedure. Nucleic Acids Res., 19: 4293, 1991.
-
(1991)
Nucleic Acids Res.
, vol.19
, pp. 4293
-
-
Laird, P.W.1
Zijderveld, A.2
Linders, K.3
Rudnicki, M.A.4
Jaenisch, R.5
Berns, A.6
-
17
-
-
0030738231
-
Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)
-
Gonzalgo, M. L., and Jones, P. A. Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE). Nucleic Acids Res., 25: 2529-2531, 1997.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 2529-2531
-
-
Gonzalgo, M.L.1
Jones, P.A.2
-
18
-
-
0028108985
-
Database of p53 gene somatic mutations in human tumors and cell lines
-
Hollstein, M., Rice, K., Greenblatt, M. S., Soussi, T., Fuchs, R., Sørlie, T., Hovig, E., Smith-Sørensen, B., Montesano, R., and Harris, C. C. Database of p53 gene somatic mutations in human tumors and cell lines. Nucleic Acids Res., 22: 3551-3555, 1994.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 3551-3555
-
-
Hollstein, M.1
Rice, K.2
Greenblatt, M.S.3
Soussi, T.4
Fuchs, R.5
Sørlie, T.6
Hovig, E.7
Smith-Sørensen, B.8
Montesano, R.9
Harris, C.C.10
-
19
-
-
0028070985
-
p16 gene in uncultured tumors
-
Spruck, C. H., III, Gonzalez-Zulueta, M., Shibata, A., Simoneau, A. R., Lin, M. F., Gonzales, F., Tsai, Y. C., and Jones, P. A. p16 gene in uncultured tumors. Nature (Lond.), 370: 183-184, 1994.
-
(1994)
Nature (Lond.)
, vol.370
, pp. 183-184
-
-
Spruck III, C.H.1
Gonzalez-Zulueta, M.2
Shibata, A.3
Simoneau, A.R.4
Lin, M.F.5
Gonzales, F.6
Tsai, Y.C.7
Jones, P.A.8
-
20
-
-
0023709002
-
A variation in the structure of the protein-coding region of the human p53 gene
-
Amst.
-
Buchman, V. L., Chumakov, P. M., Ninkina, N. N., Samarina, O. P., and Georgiev, G. P. A variation in the structure of the protein-coding region of the human p53 gene. Gene (Amst.), 70: 245-252, 1988.
-
(1988)
Gene
, vol.70
, pp. 245-252
-
-
Buchman, V.L.1
Chumakov, P.M.2
Ninkina, N.N.3
Samarina, O.P.4
Georgiev, G.P.5
-
21
-
-
0028875205
-
Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing
-
Gonzalez-Zulueta, M., Bender, C. M., Yang, A. S., Nguyen, T., Beart, R. W., Van Tornout, J. M., and Jones, P. A. Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res., 55: 4531-4535, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 4531-4535
-
-
Gonzalez-Zulueta, M.1
Bender, C.M.2
Yang, A.S.3
Nguyen, T.4
Beart, R.W.5
Van Tornout, J.M.6
Jones, P.A.7
-
22
-
-
0032521402
-
The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines
-
Gonzalgo, M. L., Hayashida, T., Bender, C. M., Pao, M. M., Tsai, Y. C., Gonzales, F. A., Nguyen, H. D., Nguyen, T. T., and Jones, P. A. The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines. Cancer Res., 58: 1245-1252, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 1245-1252
-
-
Gonzalgo, M.L.1
Hayashida, T.2
Bender, C.M.3
Pao, M.M.4
Tsai, Y.C.5
Gonzales, F.A.6
Nguyen, H.D.7
Nguyen, T.T.8
Jones, P.A.9
-
23
-
-
0030778842
-
ARF
-
ARF. Cell, 91: 555-558, 1997.
-
(1997)
Cell
, vol.91
, pp. 555-558
-
-
Haber, D.A.1
-
24
-
-
0028036255
-
Two molecular pathways to transitional cell carcinoma of the bladder
-
Spruck, C. H., III, Ohneseit, P. F., Gonzalez-Zulueta, M., Esrig, D., Miyao, N., Tsai, Y. C., Lerner, S. P., Schmütte, C., Yang, A. S., Cote, R., Dubeau, L., Nichols, P., Hermann, G. G., Steven, K., Horn, T., Skinner, D. G., and Jones, P. A. Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res., 54: 784-788, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 784-788
-
-
Spruck III, C.H.1
Ohneseit, P.F.2
Gonzalez-Zulueta, M.3
Esrig, D.4
Miyao, N.5
Tsai, Y.C.6
Lerner, S.P.7
Schmütte, C.8
Yang, A.S.9
Cote, R.10
Dubeau, L.11
Nichols, P.12
Hermann, G.G.13
Steven, K.14
Horn, T.15
Skinner, D.G.16
Jones, P.A.17
-
25
-
-
0030920089
-
Alterations of tumor suppressor genes in bladder cancer
-
Cordon-Cardo, C., and Reuter, V. E. Alterations of tumor suppressor genes in bladder cancer. Semin. Diagn. Pathol., 14: 123-132, 1997.
-
(1997)
Semin. Diagn. Pathol.
, vol.14
, pp. 123-132
-
-
Cordon-Cardo, C.1
Reuter, V.E.2
-
26
-
-
0026504931
-
Frequent association of p53 gene mutation in invasive bladder cancer
-
Fujimoto, K., Yamada, Y., Okajima, E., Kakizoe, T., Sasaki, H., Sugimura, T., and Terada, M. Frequent association of p53 gene mutation in invasive bladder cancer. Cancer Res., 52: 1393-1398, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 1393-1398
-
-
Fujimoto, K.1
Yamada, Y.2
Okajima, E.3
Kakizoe, T.4
Sasaki, H.5
Sugimura, T.6
Terada, M.7
-
27
-
-
0029005856
-
Genetic evidence in melanoma and bladder cancers that p16 and p53 function in separate pathways of tumor suppression
-
Gruis, N. A., Weaver-Feldhaus, J., Liu, Q., Frye, C., Eeles, R., Orlow, I., Lacombe, L., Ponce-Castaneda, V., Lianes, P., Latres, E., Skolnick, M., Cordon-Cardo, C., and Kamb, A. Genetic evidence in melanoma and bladder cancers that p16 and p53 function in separate pathways of tumor suppression. Am. J. Pathol., 146: 1199-1206, 1995.
-
(1995)
Am. J. Pathol.
, vol.146
, pp. 1199-1206
-
-
Gruis, N.A.1
Weaver-Feldhaus, J.2
Liu, Q.3
Frye, C.4
Eeles, R.5
Orlow, I.6
Lacombe, L.7
Ponce-Castaneda, V.8
Lianes, P.9
Latres, E.10
Skolnick, M.11
Cordon-Cardo, C.12
Kamb, A.13
-
28
-
-
15444339879
-
Overcoming cellular senescence in human cancer pathogenesis
-
Yeager, T. R., DeVries, S., Jarrard, D. F., Kao, C., Nakada, S. Y., Moon, T. D., Bruskewitz, R., Stadler, W. M., Meisner, L. F., Gilchrist, K. W., Newton, M. A., Waldman, F. M., and Reznikoff, C. A. Overcoming cellular senescence in human cancer pathogenesis. Genes Dev., 12: 163-174, 1998.
-
(1998)
Genes Dev.
, vol.12
, pp. 163-174
-
-
Yeager, T.R.1
DeVries, S.2
Jarrard, D.F.3
Kao, C.4
Nakada, S.Y.5
Moon, T.D.6
Bruskewitz, R.7
Stadler, W.M.8
Meisner, L.F.9
Gilchrist, K.W.10
Newton, M.A.11
Waldman, F.M.12
Reznikoff, C.A.13
-
29
-
-
0023125537
-
Primary structure polymorphism at amino acid residue 72 of human p53
-
Matlashewski, G. J., Tuck, S., Pim, D., Lamb, P., Schneider, J., and Crawford, L. V. Primary structure polymorphism at amino acid residue 72 of human p53. Mol. Cell. Biol., 7: 961-963, 1987.
-
(1987)
Mol. Cell. Biol.
, vol.7
, pp. 961-963
-
-
Matlashewski, G.J.1
Tuck, S.2
Pim, D.3
Lamb, P.4
Schneider, J.5
Crawford, L.V.6
-
30
-
-
7144250518
-
Role of a p53 polymorphism in the development of human papillomavirus associated cancer
-
Storey, A., Thomas, M., Kalita, A., Harwood, C., Gardiol, D., Mantovani, F., Breuer, J., Leigh, I. M., Matlashewski, G., and Banks, L. Role of a p53 polymorphism in the development of human papillomavirus associated cancer. Nature (Lond.), 393: 229-234, 1998.
-
(1998)
Nature (Lond.)
, vol.393
, pp. 229-234
-
-
Storey, A.1
Thomas, M.2
Kalita, A.3
Harwood, C.4
Gardiol, D.5
Mantovani, F.6
Breuer, J.7
Leigh, I.M.8
Matlashewski, G.9
Banks, L.10
-
31
-
-
0029670840
-
CDKN2 expression and its implications for cell immortalization and senescence
-
CDKN2 expression and its implications for cell immortalization and senescence. Mol. Cell. Biol., 16: 859-867, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 859-867
-
-
Hara, E.1
Smith, R.2
Parry, D.3
Tahara, H.4
Stone, S.5
Peters, G.6
-
32
-
-
0029980043
-
p53 in growth control and neoplasia
-
Gottlieb, T. M., and Oren, M. p53 in growth control and neoplasia. Biochim. Biophys. Acta, 1287: 77-102, 1996.
-
(1996)
Biochim. Biophys. Acta
, vol.1287
, pp. 77-102
-
-
Gottlieb, T.M.1
Oren, M.2
-
33
-
-
0029972806
-
p53: Puzzle and paradigm
-
Ko, L. J., and Prives, C. p53: puzzle and paradigm. Genes Dev., 10: 1054-1072, 1996.
-
(1996)
Genes Dev.
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
|