메뉴 건너뛰기




Volumn 104, Issue 2, 2004, Pages 535-542

Positive and negative regulatory roles of the WW-like domain in TEL-PDGFβR transformation

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; HYBRID PROTEIN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN TYROSINE KINASE; TEL PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; TEL PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR KINASE; TRYPTOPHAN; UNCLASSIFIED DRUG;

EID: 3142519560     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2004-01-0169     Document Type: Article
Times cited : (8)

References (36)
  • 1
    • 0028224348 scopus 로고
    • Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
    • Golub TR, Barker GF, Lovett M, Gilliland DG. Fusion of PDGF receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell. 1994;77:307-316.
    • (1994) Cell , vol.77 , pp. 307-316
    • Golub, T.R.1    Barker, G.F.2    Lovett, M.3    Gilliland, D.G.4
  • 2
    • 0029966854 scopus 로고    scopus 로고
    • The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways
    • Carroll M, Tomasson MH, Barker GF, Golub TR, Gilliland DG. The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways. Proc Natl Acad Sci U S A. 1996;93:14845-14850.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14845-14850
    • Carroll, M.1    Tomasson, M.H.2    Barker, G.F.3    Golub, T.R.4    Gilliland, D.G.5
  • 3
    • 17144463437 scopus 로고    scopus 로고
    • A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein
    • Jousset C, Carron C, Boureux A, et al. A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein. EMBO J. 1997;16:69-82.
    • (1997) EMBO J , vol.16 , pp. 69-82
    • Jousset, C.1    Carron, C.2    Boureux, A.3
  • 4
    • 0033999917 scopus 로고    scopus 로고
    • Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581
    • Tomasson MH, Sternberg DW, Williams IR, et al. Fatal myeloproliferation, induced in mice by TEL/PDGFbetaR expression, depends on PDGFbetaR tyrosines 579/581. J Clin Invest. 2000;105:423-432.
    • (2000) J Clin Invest , vol.105 , pp. 423-432
    • Tomasson, M.H.1    Sternberg, D.W.2    Williams, I.R.3
  • 5
    • 0033084227 scopus 로고    scopus 로고
    • TEL/PDGFbetaR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor
    • Tomasson MH, Williams IR, Hasserjian R, et al. TEL/PDGFbetaR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor. Blood. 1999;93:1707-1714.
    • (1999) Blood , vol.93 , pp. 1707-1714
    • Tomasson, M.H.1    Williams, I.R.2    Hasserjian, R.3
  • 6
    • 0028589148 scopus 로고
    • Platelet-derived growth factor receptor signals
    • Claesson-Welsh L. Platelet-derived growth factor receptor signals. J Biol Chem. 1994;269:32023-32026.
    • (1994) J Biol Chem , vol.269 , pp. 32023-32026
    • Claesson-Welsh, L.1
  • 7
    • 0032547385 scopus 로고    scopus 로고
    • Signal transduction via platelet-derived growth factor receptors
    • Heldin CH, Ostman A, Ronnstrand L. Signal transduction via platelet-derived growth factor receptors. Biochim Biophys Acta. 1998;1378:F79-F113.
    • (1998) Biochim Biophys Acta , vol.1378
    • Heldin, C.H.1    Ostman, A.2    Ronnstrand, L.3
  • 8
    • 0027211693 scopus 로고
    • Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal
    • Valius M, Kazlauskas A. Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal. Cell. 1993;73:321-334.
    • (1993) Cell , vol.73 , pp. 321-334
    • Valius, M.1    Kazlauskas, A.2
  • 9
    • 0033625358 scopus 로고    scopus 로고
    • TEL/PDGFbetaR fusion protein activates STAT1 and STAT5: A common mechanism for transformation by tyrosine kinase fusion proteins
    • Wilbanks AM, Mahajan S, Frank DA, Druker BJ, Gilliland DG, Carroll M. TEL/PDGFbetaR fusion protein activates STAT1 and STAT5: a common mechanism for transformation by tyrosine kinase fusion proteins. Exp Hematol. 2000;28:584-593.
    • (2000) Exp Hematol , vol.28 , pp. 584-593
    • Wilbanks, A.M.1    Mahajan, S.2    Frank, D.A.3    Druker, B.J.4    Gilliland, D.G.5    Carroll, M.6
  • 10
    • 0035542766 scopus 로고    scopus 로고
    • The TEL/PDGFbetaR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways
    • Sternberg DW, Tomasson MH, Carroll M, et al. The TEL/PDGFbetaR fusion in chronic myelomonocytic leukemia signals through STAT5-dependent and STAT5-independent pathways. Blood. 2001;98:3390-3397.
    • (2001) Blood , vol.98 , pp. 3390-3397
    • Sternberg, D.W.1    Tomasson, M.H.2    Carroll, M.3
  • 11
    • 0035877975 scopus 로고    scopus 로고
    • H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor beta gene in atypical chronic myeloid leukemia with t(5; 10)(q33;q22)
    • Schwaller J, Anastasiadou E, Cain D, et al. H4(D10S170), a gene frequently rearranged in papillary thyroid carcinoma, is fused to the platelet-derived growth factor receptor beta gene in atypical chronic myeloid leukemia with t(5; 10)(q33;q22). Blood. 2001;97:3910-3918.
    • (2001) Blood , vol.97 , pp. 3910-3918
    • Schwaller, J.1    Anastasiadou, E.2    Cain, D.3
  • 12
    • 0033529599 scopus 로고    scopus 로고
    • Transforming properties of the Huntingtin interacting protein 1/platelet-derived growth factor beta receptor fusion protein
    • Ross TS, Gilliland DG. Transforming properties of the Huntingtin interacting protein 1/platelet-derived growth factor beta receptor fusion protein. J Biol Chem. 1999;274:22328-22336.
    • (1999) J Biol Chem , vol.274 , pp. 22328-22336
    • Ross, T.S.1    Gilliland, D.G.2
  • 13
    • 0031864246 scopus 로고    scopus 로고
    • Fusion of Huntingtin interacting protein 1 to platelet-derived growth factor beta receptor (PDGFbetaR) in chronic myelomonocytic leukemia with t(5;7)(q33;q11.2)
    • Ross TS, Bernard OA, Berger R, Gilliland DG. Fusion of Huntingtin interacting protein 1 to platelet-derived growth factor beta receptor (PDGFbetaR) in chronic myelomonocytic leukemia with t(5;7)(q33;q11.2). Blood. 1998;91:4419-4426.
    • (1998) Blood , vol.91 , pp. 4419-4426
    • Ross, T.S.1    Bernard, O.A.2    Berger, R.3    Gilliland, D.G.4
  • 14
    • 0035889128 scopus 로고    scopus 로고
    • Rabaptin-5 is a novel fusion partner to platelet-derived growth factor beta receptor in chronic myelomonocytic leukemia
    • Magnusson MK, Meade KE, Brown KE, et al. Rabaptin-5 is a novel fusion partner to platelet-derived growth factor beta receptor in chronic myelomonocytic leukemia. Blood. 2001;98:2518-2525.
    • (2001) Blood , vol.98 , pp. 2518-2525
    • Magnusson, M.K.1    Meade, K.E.2    Brown, K.E.3
  • 15
    • 0032401747 scopus 로고    scopus 로고
    • A single amino acid substitution in a WW-like domain of diverse members of the PDGF receptor subfamily of tyrosine kinases causes constitutive receptor activation
    • Irusta PM, DiMaio D. A single amino acid substitution in a WW-like domain of diverse members of the PDGF receptor subfamily of tyrosine kinases causes constitutive receptor activation. EMBO J. 1998;17:6912-6923.
    • (1998) EMBO J , vol.17 , pp. 6912-6923
    • Irusta, P.M.1    DiMaio, D.2
  • 16
    • 0037064087 scopus 로고    scopus 로고
    • Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor
    • Irusta PM, Luo Y, Bakht O, Lai CC, Smith SO, DiMaio D. Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor. J Biol Chem. 2002;277:38627-38634.
    • (2002) J Biol Chem , vol.277 , pp. 38627-38634
    • Irusta, P.M.1    Luo, Y.2    Bakht, O.3    Lai, C.C.4    Smith, S.O.5    DiMaio, D.6
  • 17
    • 0028283579 scopus 로고
    • Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product
    • Sudol M. Yes-associated protein (YAP65) is a proline-rich phosphoprotein that binds to the SH3 domain of the Yes proto-oncogene product. Oncogene. 1994;9:2145-2152.
    • (1994) Oncogene , vol.9 , pp. 2145-2152
    • Sudol, M.1
  • 18
    • 0029146950 scopus 로고
    • Characterization of a novel protein-binding module - The WW domain
    • Sudol M, Chen HI, Bougeret C, Einbond A, Bork P. Characterization of a novel protein-binding module - the WW domain. FEBS Lett. 1995;369:67-71.
    • (1995) FEBS Lett , vol.369 , pp. 67-71
    • Sudol, M.1    Chen, H.I.2    Bougeret, C.3    Einbond, A.4    Bork, P.5
  • 19
    • 0034704216 scopus 로고    scopus 로고
    • NeW wrinkles for an old domain
    • Sudol M, Hunter T. NeW wrinkles for an old domain. Cell. 2000;103:1001-1004.
    • (2000) Cell , vol.103 , pp. 1001-1004
    • Sudol, M.1    Hunter, T.2
  • 20
    • 0027988814 scopus 로고
    • The WW domain: A signalling site in dystrophin?
    • Bork P, Sudol M. The WW domain: a signalling site in dystrophin? Trends Biochem Sci. 1994;19:531-533.
    • (1994) Trends Biochem Sci , vol.19 , pp. 531-533
    • Bork, P.1    Sudol, M.2
  • 21
    • 0032541641 scopus 로고    scopus 로고
    • From Src Homology domains to other signaling modules: Proposal of the 'protein recognition code'
    • Sudol M. From Src Homology domains to other signaling modules: proposal of the 'protein recognition code'. Oncogene. 1998;17:1469-1474.
    • (1998) Oncogene , vol.17 , pp. 1469-1474
    • Sudol, M.1
  • 22
    • 15644363454 scopus 로고    scopus 로고
    • Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors
    • Hirota S, Isozaki K, Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors. Science. 1998;279:577-580.
    • (1998) Science , vol.279 , pp. 577-580
    • Hirota, S.1    Isozaki, K.2    Moriyama, Y.3
  • 23
    • 0031848146 scopus 로고    scopus 로고
    • Familial gastrointestinal stromal tumours with germline mutation of the KIT gene
    • Nishida T, Hirota S, Taniguchi M, et al. Familial gastrointestinal stromal tumours with germline mutation of the KIT gene. Nat Genet. 1998;19:323-324.
    • (1998) Nat Genet , vol.19 , pp. 323-324
    • Nishida, T.1    Hirota, S.2    Taniguchi, M.3
  • 24
    • 0030032943 scopus 로고    scopus 로고
    • Constitutive activation of c-kit in FMA3 murine mastocytoma cells caused by deletion of seven amino acids at the juxtamembrane domain
    • Tsujimura T, Morimoto M, Hashimoto K, et al. Constitutive activation of c-kit in FMA3 murine mastocytoma cells caused by deletion of seven amino acids at the juxtamembrane domain. Blood. 1996;87:273-283.
    • (1996) Blood , vol.87 , pp. 273-283
    • Tsujimura, T.1    Morimoto, M.2    Hashimoto, K.3
  • 25
    • 0028258512 scopus 로고
    • Activating mutations of the c-kit proto-oncogene in a human mast cell leukemia cell line
    • Kanakura Y, Furitsu T, Tsujimura T, et al. Activating mutations of the c-kit proto-oncogene in a human mast cell leukemia cell line. Leukemia. 1994;8(suppl 1):S18-S22.
    • (1994) Leukemia , vol.8 , Issue.SUPPL. 1
    • Kanakura, Y.1    Furitsu, T.2    Tsujimura, T.3
  • 26
    • 0028959163 scopus 로고
    • Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines
    • Kitayama H, Kanakura Y, Furitsu T, et al. Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines. Blood. 1995;85:790-798.
    • (1995) Blood , vol.85 , pp. 790-798
    • Kitayama, H.1    Kanakura, Y.2    Furitsu, T.3
  • 27
    • 0035871889 scopus 로고    scopus 로고
    • Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies
    • Yamamoto Y, Kiyoi H, Nakano Y, et al. Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies. Blood. 2001;97:2434-2439.
    • (2001) Blood , vol.97 , pp. 2434-2439
    • Yamamoto, Y.1    Kiyoi, H.2    Nakano, Y.3
  • 28
    • 0030451722 scopus 로고    scopus 로고
    • Internal tandem duplication of the flt3 gene found in acute myeloid leukemia
    • Nakao M, Yokota S, Iwai T, et al. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia. Leukemia. 1996;10:1911-1918.
    • (1996) Leukemia , vol.10 , pp. 1911-1918
    • Nakao, M.1    Yokota, S.2    Iwai, T.3
  • 29
    • 16944365287 scopus 로고    scopus 로고
    • Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies: A study on a large series of patients and cell lines
    • Yokota S, Kiyoi H, Nakao M, et al. Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies: a study on a large series of patients and cell lines. Leukemia. 1997;11:1605-1609.
    • (1997) Leukemia , vol.11 , pp. 1605-1609
    • Yokota, S.1    Kiyoi, H.2    Nakao, M.3
  • 30
    • 0032530972 scopus 로고    scopus 로고
    • Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
    • Schwaller J, Frantsve J, Aster J, et al. Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes. EMBO J. 1998;17:5321-5333.
    • (1998) EMBO J , vol.17 , pp. 5321-5333
    • Schwaller, J.1    Frantsve, J.2    Aster, J.3
  • 31
    • 0034678609 scopus 로고    scopus 로고
    • Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia
    • Liu Q, Schwaller J, Kutok J, et al. Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia. EMBO J. 2000;19:1827-1838.
    • (2000) EMBO J , vol.19 , pp. 1827-1838
    • Liu, Q.1    Schwaller, J.2    Kutok, J.3
  • 32
    • 0030921664 scopus 로고    scopus 로고
    • Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo
    • Persons DA, Allay JA, Allay ER, et al. Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo. Blood. 1997;90:1777-1786.
    • (1997) Blood , vol.90 , pp. 1777-1786
    • Persons, D.A.1    Allay, J.A.2    Allay, E.R.3
  • 33
    • 0033607151 scopus 로고    scopus 로고
    • Characterization of the structure and function of W → F WW domain variants: Identification of a natively unfolded protein that folds upon ligand binding
    • Koepf EK, Petrassi HM, Ratnaswamy G, Huff ME, Sudol M, Kelly JW. Characterization of the structure and function of W → F WW domain variants: identification of a natively unfolded protein that folds upon ligand binding. Biochemistry. 1999;38:14338-14351.
    • (1999) Biochemistry , vol.38 , pp. 14338-14351
    • Koepf, E.K.1    Petrassi, H.M.2    Ratnaswamy, G.3    Huff, M.E.4    Sudol, M.5    Kelly, J.W.6
  • 34
    • 0030424581 scopus 로고    scopus 로고
    • Structure and function of the WW domain
    • Sudol M. Structure and function of the WW domain. Prog Biophys Mol Biol. 1996;65:113-132.
    • (1996) Prog Biophys Mol Biol , vol.65 , pp. 113-132
    • Sudol, M.1
  • 35
    • 0029775570 scopus 로고    scopus 로고
    • Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide
    • Macias MJ, Hyvonen M, Baraldi E, et al. Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide. Nature. 1996;382:646-649.
    • (1996) Nature , vol.382 , pp. 646-649
    • Macias, M.J.1    Hyvonen, M.2    Baraldi, E.3
  • 36
    • 0030858496 scopus 로고    scopus 로고
    • Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands
    • Chen HI, Einbond A, Kwak SJ, et al. Characterization of the WW domain of human yes-associated protein and its polyproline-containing ligands. J Biol Chem. 1997;272:17070-17077.
    • (1997) J Biol Chem , vol.272 , pp. 17070-17077
    • Chen, H.I.1    Einbond, A.2    Kwak, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.