Membrane lipids and vesicular traffic

Current Opinion in Cell Biology

Volumn 16, Issue 4, 2004, Pages 373-378

  Van Meer, Gerrit ^a   Sprong, Hein ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

endoplamsic reticulum; ER; glycosylphosphatidylinositol; GPI

Indexed keywords

AMINOPHOSPHOLIPID; LIPID BINDING PROTEIN; MEMBRANE LIPID; PHOSPHOLIPID; POLYPHOSPHOINOSITIDE; SPHINGOLIPID;

CELL METABOLISM; CELL ORGANELLE; CELL TRANSPORT; CELL VACUOLE; CELLULAR DISTRIBUTION; CYTOSOL; ENDOCYTOSIS; MEMBRANE VESICLE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TARGETING; PROTEIN TRANSPORT; REVIEW;

ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CELL MEMBRANE; CYTOPLASMIC VESICLES; ENDOCYTOSIS; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; LIPID METABOLISM; MEMBRANE FUSION; MEMBRANE LIPIDS; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPIDS; VESICULAR TRANSPORT PROTEINS;

EID: 3142516233     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ceb.2004.06.004     Document Type: Review

References (50)

1. Sprong H., van der Sluijs P., van Meer G. How proteins move lipids and lipids move proteins. Nat Rev Mol Cell Biol. 2:2001;504-513
2. Kooijman E.E., Chupin V., de Kruijff B., Burger K.N. Modulation of membrane curvature by phosphatidic acid and lysophosphatidic acid. Traffic. 4:2003;162-174
3. Matsuo H., Chevallier J., Mayran N., Le Blanc I., Ferguson C., Faure J., Blanc N.S., Matile S., Dubochet J., Sadoul R., et al. Role of LBPA and Alix in multivesicular liposome formation and endosome organization. Science. 303:2004;531-534 The biologically active 2, 2′-stereoisomer of lysobisphosphatidic acid has the intrinsic capacity to drive vesicle budding and fission into acidified liposomes, a situation resembling late endosomal structures. Paradoxically, the cytosolic LBPA-binding protein Alix, also found in exosomes, inhibits invagination in vitro, but is required for the biogenesis of multivesicular endosomes in vivo.
4. Modregger J., Schmidt A.A., Ritter B., Huttner W.B., Plomann M. Characterization of Endophilin B1b, a brain-specific membrane-associated lysophosphatidic acid acyl transferase with properties distinct from endophilin A1. J Biol Chem. 278:2003;4160-4167
5. Nardini M., Spano S., Cericola C., Pesce A., Massaro A., Millo E., Luini A., Corda D., Bolognesi M. CtBP/BARS: a dual-function protein involved in transcription co-repression and Golgi membrane fission. EMBO J. 22:2003;3122-3130
6. Shemesh T., Luini A., Malhotra V., Burger K.N., Kozlov M.M. Prefission constriction of Golgi tubular carriers driven by local lipid metabolism: a theoretical model. Biophys J. 85:2003;3813-3827
7. Farge E., Ojcius D.M., Subtil A., Dautry-Varsat A. Enhancement of endocytosis due to aminophospholipid transport across the plasma membrane of living cells. Am J Physiol. 276:1999;C725-C733
8. Chernomordik L.V., Kozlov M.M. Protein-lipid interplay in fusion and fission of biological membranes. Annu Rev Biochem. 72:2003;175-207
9. Baumgart T., Hess S.T., Webb W.W. Imaging coexisting fluid domains in biomembrane models coupling curvature and line tension. Nature. 425:2003;821-824
10. Munro S. Lipid rafts: elusive or illusive? Cell. 115:2003;377-388 A thorough discussion of the limitations of the various methods to study lipid rafts. The author challenges cell biologists to develop adequate tools for assessing the existence of cellular rafts. Unfortunately, the compelling evidence on lipid sorting in vesicular traffic [31, 32, 43] does not receive proper credit from the author.
11. Czech M.P. Dynamics of phosphoinositides in membrane retrieval and insertion. Annu Rev Physiol. 65:2003;791-815
12. Bremser M., Nickel W., Schweikert M., Ravazzola M., Amherdt M., Hughes C.A., Söllner T.H., Rothman J.E., Wieland F.T. Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors. Cell. 96:1999;495-506
13. Bigay J., Gounon P., Robineau S., Antonny B. Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature. Nature. 426:2003;563-566
14. Hua Z., Graham T.R. Requirement for neo1p in retrograde transport from the Golgi complex to the endoplasmic reticulum. Mol Biol Cell. 14:2003;4971-4983
15. Pomorski T., Lombardi R., Riezman H., Devaux P.F., Van Meer G., Holthuis J.C. Drs2p-related P-type ATPases Dnf1p and Dnf2p are required for phospholipid translocation across the yeast plasma membrane and serve a role in endocytosis. Mol Biol Cell. 14:2003;1240-1254
16. •]) is a breakthrough in studies on sphingolipid metabolism and organization in the Golgi. Based on the prediction that the active center would be similar to that of the lipid phosphate phosphatase (LPP) family, the authors employ a functional cloning strategy in yeast to identify two mammalian sphingomyelin synthases, SMS1 in the Golgi and SMS2 at the plasma membrane, where it is presumably active in ceramide/diacylglycerol-mediated signaling events.
17. •], SMS1 is cloned by expression cloning. Using a lymphoid cell line lacking SMS1, it is observed that SMS1 is required for growth under serum-free conditions.
18. •]. CERT has binding sites for ER and Golgi and may function at contact sites.
19. Brügger B., Sandhoff R., Wegehingel S., Gorgas K., Malsam J., Helms J.B., Lehmann W.D., Nickel W., Wieland F.T. Evidence for segregation of sphingomyelin and cholesterol during formation of COPI-coated vesicles. J Cell Biol. 151:2000;507-518
20. Drecktrah D., Chambers K., Racoosin E.L., Cluett E.B., Gucwa A., Jackson B., Brown W.J. Inhibition of a Golgi complex lysophospholipid acyltransferase induces membrane tubule formation and retrograde trafficking. Mol Biol Cell. 14:2003;3459-3469
21. Glebov O.O., Nichols B.J. Lipid raft proteins have a random distribution during localized activation of the T-cell receptor. Nat Cell Biol. 6:2004;238-243
22. Nichols B.J. GM1-containing lipid rafts are depleted within clathrin-coated pits. Curr Biol. 13:2003;686-690
23. Sharma P., Varma R., Sarasij R.C., Ira, Gousset K., Krishnamoorthy G., Rao M., Mayor S. Nanoscale organization of multiple GPI-anchored proteins in living cell membranes. Cell. 116:2004;577-589
24. Zacharias D.A., Violin J.D., Newton A.C., Tsien R.Y. Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells. Science. 296:2002;913-916
25. Stüven E., Porat A., Shimron F., Fass E., Kaloyanova D., Brügger B., Wieland F.T., Elazar Z., Helms J.B. Intra-Golgi protein transport depends on a cholesterol balance in the lipid membrane. J Biol Chem. 278:2003;53112-53122
26. Ying M., Grimmer S., Iversen T.G., Van Deurs B., Sandvig K. Cholesterol loading induces a block in the exit of VSVG from the TGN. Traffic. 4:2003;772-784
27. de Almeida R.F., Fedorov A., Prieto M. Sphingomyelin/phosphatidylcholine/ cholesterol phase diagram: boundaries and composition of lipid rafts. Biophys J. 85:2003;2406-2416
28. Schnabl M., Oskolkova O.V., Holic R., Brezna B., Pichler H., Zagorsek M., Kohlwein S.D., Paltauf F., Daum G., Griac P. Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover. Eur J Biochem. 270:2003;3133-3145
29. Alb J.G. Jr., Cortese J.D., Phillips S.E., Albin R.L., Nagy T.R., Hamilton B.A., Bankaitis V.A. Mice lacking phosphatidylinositol transfer protein-α exhibit spinocerebellar degeneration, intestinal and hepatic steatosis, and hypoglycemia. J Biol Chem. 278:2003;33501-33518
30. Alb J.G. Jr., Phillips S.E., Rostand K., Cui X., Pinxteren J., Cotlin L., Manning T., Guo S., York J.D., Sontheimer H., et al. Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cells. Mol Biol Cell. 13:2002;739-754
31. Singh R.D., Puri V., Valiyaveettil J.T., Marks D.L., Bittman R., Pagano R.E. Selective caveolin-1-dependent endocytosis of glycosphingolipids. Mol Biol Cell. 14:2003;3254-3265
32. Parton R.G. Ultrastructural localization of gangliosides; GM1 is concentrated in caveolae. J Histochem Cytochem. 42:1994;155-166
33. del Pozo M.A., Alderson N.B., Kiosses W.B., Chiang H.H., Anderson R.G., Schwartz M.A. Integrins regulate Rac targeting by internalization of membrane domains. Science. 303:2004;839-842
34. Sharma D.K., Choudhury A., Singh R.D., Wheatley C.L., Marks D.L., Pagano R.E. Glycosphingolipids internalized via caveolar-related endocytosis rapidly merge with the clathrin pathway in early endosomes and form microdomains for recycling. J Biol Chem. 278:2003;7564-7572
35. Fujinaga Y., Wolf A.A., Rodighiero C., Wheeler H., Tsai B., Allen L., Jobling M.G., Rapoport T., Holmes R.K., Lencer W.I. Gangliosides that associate with lipid rafts mediate transport of cholera and related toxins from the plasma membrane to endoplasmic reticulum. Mol Biol Cell. 14:2003;4783-4793
36. Puri V., Jefferson J.R., Singh R.D., Wheatley C.L., Marks D.L., Pagano R.E. Sphingolipid storage induces accumulation of intracellular cholesterol by stimulating SREBP-1 cleavage. J Biol Chem. 278:2003;20961-20970
37. Altmann S.W., Davis H.R. Jr., Zhu L.J., Yao X., Hoos L.M., Tetzloff G., Iyer S.P., Maguire M., Golovko A., Zeng M., et al. Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science. 303:2004;1201-1204 Convincing evidence that this class of sterol-sensing-domain- containing proteins are involved in cholesterol transport. The challenge is to unravel their mechanism of action. Cholesterol may not be the primary substrate and other proteins (and lipids) may be involved. Mammalian sterol-sensing domains may actually sense sterols, whereas in flies such a domain recognizes a sterol-independent membrane property [46].
38. Malathi K., Higaki K., Tinkelenberg A.H., Balderes D.A., Almanzar-Paramio D., Wilcox L.J., Erdeniz N., Redican F., Padamsee M., Liu Y., et al. Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution. J Cell Biol. 164:2004;547-556
39. Mayran N., Parton R.G., Gruenberg J. Annexin II regulates multivesicular endosome biogenesis in the degradation pathway of animal cells. EMBO J. 22:2003;3242-3253
40. Zobiack N., Rescher U., Ludwig C., Zeuschner D., Gerke V. The annexin 2/S100A10 complex controls the distribution of transferrin receptor-containing recycling endosomes. Mol Biol Cell. 14:2003;4896-4908
41. Gagnon E., Duclos S., Rondeau C., Chevet E., Cameron P.H., Steele-Mortimer O., Paiement J., Bergeron J.J., Desjardins M. Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell. 110:2002;119-131
42. De Rosa M.F., Sillence D., Ackerley C., Lingwood C. Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesis. J Biol Chem. 279:2004;7867-7876
43. Maier O., Hoekstra D. Trans-Golgi network and subapical compartment of HepG2 cells display different properties in sorting and exiting of sphingolipids. J Biol Chem. 278:2003;164-173
44. Möbius W., van Donselaar E., Ohno-Iwashita Y., Shimada Y., Heijnen H.F., Slot J.W., Geuze H.J. Recycling compartments and the internal vesicles of multivesicular bodies harbor most of the cholesterol found in the endocytic pathway. Traffic. 4:2003;222-231
45. Murk J.L., Humbel B.M., Ziese U., Griffith J.M., Posthuma G., Slot J.W., Koster A.J., Verkleij A.J., Geuze H.J., Kleijmeer M.J. Endosomal compartmentalization in three dimensions: implications for membrane fusion. Proc Natl Acad Sci USA. 100:2003;13332-13337
46. Dobrosotskaya I.Y., Goldstein J.L., Brown M.S., Rawson R.B. Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs. J Biol Chem. 278:2003;35837-35843
47. Brügger B., Graham C., Leibrecht I., Mombelli E., Jen A., Wieland F., Morris R. The membrane domains occupied by glycosylphosphatidylinositol- anchored prion protein and Thy-1 differ in lipid composition. J Biol Chem. 279:2004;7530-7536
48. Lommerse P.H., Blab G.A., Cognet L., Harms G.S., Snaar-Jagalska B.E., Spaink H.P., Schmidt T. Single-molecule imaging of the H-ras membrane-anchor reveals domains in the cytoplasmic leaflet of the cell membrane. Biophys J. 86:2004;609-616
49. Godi A., Di Campli A., Konstantakopoulos A., Di Tullio G., Alessi D.R., Kular G.S., Daniele T., Marra P., Lucocq J.M., De Matteis M.A. FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P. Nat Cell Biol. 6:2004;393-404
50. Sleat D.E., Wiseman J.A., El-Banna M., Price S.M., Verot L., Shen M.M., Tint G.S., Vanier M.T., Walkley S.U., Lobel P. Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport. Proc Natl Acad Sci U S A. 101:2004;5886-5891