Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover

European Journal of Biochemistry

Volumn 270, Issue 15, 2003, Pages 3133-3145

  Schnabl, Martina ^a   Oskolkova, Olga V ^a   Holič, Roman ^b   Brežná, Barbara ^b   Pichler, Harald ^d   Zágoršek, Miloš ^b   Kohlwein, Sepp D ^c   Paltauf, Fritz ^a   Daum, Günther ^a   Griač, Peter ^b  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

^c UNIVERSITY OF GRAZ   (Austria)

^d NONE

Author keywords

Phosphatidylcholine; Phospholipase; SEC14; Sec14 homologues; Subcellular localization

Indexed keywords

FUNGAL PROTEIN; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; LYSOPHOSPHOLIPASE; PHOSPHATIDYLCHOLINE; PHOSPHOLIPASE; PHOSPHOLIPASE D1; PROTEIN SEC14; PROTEIN SFH1; PROTEIN SFH2; PROTEIN SFH3; PROTEIN SFH4; PROTEIN SFH5; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; GENE OVEREXPRESSION; METABOLIC REGULATION; MICROSOME; NONHUMAN; PHOSPHOLIPID METABOLISM; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

CARRIER PROTEINS; FUNGAL PROTEINS; GENETIC COMPLEMENTATION TEST; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; MUTATION; PHENOTYPE; PHOSPHATIDYLCHOLINES; PHOSPHOLIPASE D; PHOSPHOLIPID TRANSFER PROTEINS; PHOSPHOLIPIDS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0041767597     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1033.2003.03688.x     Document Type: Article

References (49)

1. Szolderits, G., Hermetter, A., Paltauf, F. & Daum, G. (1989) Membrane properties modulate the activity of a phosphatidylinositol transfer protein from the yeast, Saccharomyces cerevisiae. Biochim. Biophys. Acta 986, 301-309.
2. Bankaitis, V.A., Aitken, J.R., Cleves, A.E. & Dowhan, W. (1990) An essential role for a phospholipid transfer protein in yeast Golgi function. Nature 347, 561-562.
3. Cleves, A.E., McGee, T.P., Whitters, E.A., Champion, K.M., Aitken, J.R., Dowhan, W., Goebl, M. & Bankaitis, V.A. (1991) Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein. Cell 64, 789-800.
4. Xie, Z., Fang, M., Rivas, M.P., Faulkner, A.J., Sternweis, P.C., Engebrecht, J.A. & Bankaitis, V.A. (1998) Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects. Proc. Natl Acad. Sci. USA 95, 12346-12351.
5. Sreenivas, A., Patton-Vogt, J.L., Bruno, V., Griac, P. & Henry, S.A. (1998) A role for phospholipase D (Pld1p) in growth, secretion, and regulation of membrane lipid synthesis in yeast. J. Biol. Chem. 273, 16635-16638.
6. Patton-Vogt, J.L., Griac, P., Sreenivas, A., Bruno, V., Dowd, S., Swede, M.J. & Henry, S.A. (1997) Role of the yeast phosphatidylinositol/phosphatidylcholine transfer protein (Sec14p) in phosphatidylcholine turnover and INO1 regulation. J. Biol. Chem. 272, 20873-20883.
7. Kent, C. & Carman, G.M. (1999) Interactions among pathways for phosphatidylcholine metabolism, CTP synthesis and secretion through the Golgi apparatus. Trends Biochem. Sci. 24, 146-150.
8. Li, X., Xie, Z. & Bankaitis, V.A. (2000) Phosphatidylinositol/phosphatidylcholine transfer proteins in yeast. Biochim. Biophys. Acta 1486, 55-71.
9. Sha, B., Phillips, S.E., Bankaitis, V.A. & Luo, M. (1998) Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer protein. Nature 391, 506-510.
10. Li, X., Routt, S.M., Xie, Z., Cui, X., Fang, M., Kearns, M.A., Bard, M., Kirsch, D.R. & Bankaitis, V.A. (2000) Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth. Mol. Biol. Cell 11, 1989-2005.
11. van den Hazel, H.B., Pichler, H., do Valle Matta, M.A., Leitner, E., Goffeau, A. & Daum, G. (1999) PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugs. J. Biol. Chem. 274, 1934-1941.
12. Wu, W.I., Routt, S., Bankaitis, V.A. & Voelker, D.R. (2000) A new gene involved in the transport-dependent metabolism of phosphatidylserine, PSTB2/PDR17, shares sequence similarity with the gene encoding the phosphatidylinositol/phosphatidylcholine transfer protein, SEC14. J. Biol. Chem. 275, 14446-14456.
13. Santos, B. & Snyder, M. (2000) Sbe2p and Sbe22p, two homologous Golgi proteins involved in yeast cell wall formation. Mol. Biol. Cell 11, 435-452.
14. Lee, K.S., Patton, J.L., Fido, M., Hines, L.K., Kohlwein, S.D., Paltauf, F., Henry, S.A. & Levin, D.E. (1994) The Saccharomyces cerevisiae PLB1 gene encodes a protein required for lysophospholipase and phospholipase B activity. J. Biol. Chem. 269, 19725-19730.
15. Gnamusch, E., Kalaus, C., Hrastnik, C., Paltauf, F. & Daum, G. (1992) Transport of phospholipids between subcellular membranes of wild-type yeast cells and of the phosphatidylinositol transfer protein-deficient strain Saccharomyces cerevisiae sec14. Biochim. Biophys. Acta 1111, 120-126.
16. Griac, P., Swede, M.J. & Henry, S.A. (1996) The role of phosphatidylcholine biosynthesis in the regulation of the INO1 gene of yeast. J. Biol. Chem. 271, 25692-25698.
17. Burke, D., Dawson, D. & Stearns, T. (2000) Methods in Yeast Genetics, a Cold Spring Harbor Laboratory Course Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
18. Gietz, D., St Jean, A., Woods, R.A. & Schiestl, R.H. (1992) Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res. 20, 1425.
19. Gietz, R.D. & Sugino, A. (1988) New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74, 527-534.
20. Wach, A., Brachat, A., Pohlmann, R. & Philippsen, P. (1994) New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast 10, 1793-1808.
21. Wach, A., Brachat, A., Alberti-Segui, C., Rebischung, C. & Philippsen, P. (1997) Heterologous HIS marker and GFP reporter modules for PCR targeting in Saccharomyces cerevisiae. Yeast 13, 1065-1075.
22. Kohlwein, S.D. (2000) The beauty of the yeast: live cell microscopy at the limits of optical resolution. Microsc. Res. Techn. 51, 511-529.
23. 2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria. J. Biol. Chem. 257, 13028-13033.
24. Zinser, E. & Daum, G. (1995) Isolation and biochemical characterization of organelles from the yeast, Saccharomyces cerevisiae. Yeast 11, 493-536.
25. Leber, R., Zinser, E., Zellnig, G., Paltauf, F. & Daum, G. (1994) Characterization of lipid particles of the yeast, Saccharomyces cerevisiae. Yeast 10, 1421-1428.
26. Hurt, E.C., McDowell, A. & Schimmang, T. (1988) Nucleolar and nuclear envelope proteins of the yeast Saccharomyces cerevisiae. Eur. J. Cell Biol. 46, 554-563.
27. Lowry, O.H., Rosebrough, N.J., Farr, A.L. & Randall, R.J. (1951) Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265-275.
28. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
29. Haid, A. & Suissa, M. (1983) Immunochemical identification of membrane proteins after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Methods Enzymol. 96, 192-205.
30. Tang, W.-J.Y. (1993) Blot-affinity purification of antibodies. Methods Cell Biol. 37, 95-104.
31. Folch, J., Lees, M. & Sloane-Stanley, G.H. (1957) A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226, 497-509.
32. Broekhuyse, R.M. (1968) Phospholipids in tissues of the eye: isolation, characterization and quantitative analysis by two-dimensional thin-layer chromatography of diacyl and vinyl-ether phospholipids. Biochim. Biophys. Acta 260, 449-459.
33. Lewis, T.A., Rodriguez, R.J. & Parks, L.W. (1987) Relationship between intracellular sterol content and sterol esterification and hydrolysis in Saccharomyces cerevisiae. Biochim. Biophys. Acta 921, 205-212.
34. Nes, W.D., Xu, S. & Haddon, W.F. (1989) Evidence for similarities and differences in the biosynthesis of fungal sterols. Steroids 53, 533-558.
35. Xu, S., Norton, R.A., Crumley, F.G. & Nes, W.D. (1988) Comparison of the chromatographic properties of sterols, select additional steroids and triterpenoids: gravity-flow column liquid chromatography, thin-layer chromatography, gas-liquid chromatography and high-performance liquid chromatography. J. Chromatogr. 452, 377-398.
36. Patterson, G.W. (1971) Relation between structure and retention time of sterols in gas chromatography. Anal. Chem. 43, 1165-1170.
37. Hawkins, P.T., Stephens, L.R. & Dowens, C.P. (1986) Rapid formation of inositol 1,3,4,5-tetrakisphosphate and inositol 1,3,4-trisphosphate in rat parotid glands may both result indirectly from receptor-stimulated release of inositol 1,4,5-trisphosphate from phosphatidylinositol 4,5-bisphosphate. Biochem. J. 238, 507-516.
38. Cook, S.R. & Wakelam, J.O. (1989) Analysis of the water-soluble products of phosphatidylcholine breakdown by ion-exchange chromatography. Bombesin and TPA (12-O-tetradecanoylphorb.ol-13-acetate) stimulate choline generation in Swiss 3T3 cells by a common mechanism. Biochem. J. 263, 581-587.
39. Dowd, S.R., Bier, M.E. & Patton-Vogt, J.L. (2001) Turnover of phosphatidylcholine in Saccharomyces cerevisiae. J. Biol. Chem. 276, 3756-3763.
40. Pichler, H., Gaigg, B., Hrastnik, C., Achleitner, G., Kohlwein, S.D., Zellnig, G., Perktold, A. & Daum, G. (2001) A subfraction of the yeast endoplasmic reticulum associates with the plasma membrane and has a high capacity to synthesize lipids. Eur. J. Biochem. 268, 2351-2361.
41. Zweytick, D., Athenstaedt, K. & Daum, G. (2000) Intracellular lipid particles of eukaryotic cells. Biochim. Biophys. Acta 1469, 101-12040.
42. Merkel, O., Fido, M., Mayr, J.A., Pruger, H., Raab, F., Zandonella, G., Kohlwein, S.D. & Paltauf, F. (1999) Characterization and function in vivo of two novel phospholipases B/lysophospholipases from Saccharomyces cerevisiae. J. Biol. Chem. 274, 28121-28127.
43. Kim, K., Kim, K.H., Storey, M.K., Voelker, D.R. & Carman, G.M. (1999) Isolation and characterization of the Saccharomyces cerevisiae EKI1 gene encoding ethanolamine kinase. J. Biol. Chem. 274, 14857-1486640.
44. Daum, G., Lees, N.D., Bard, M. & Dickson, R. (1998) Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiae. Yeast 14, 1471-1510.
45. Regnacq, M., Ferreira, T., Puard, J. & Berges, T. (2002) SUT1 suppresses sec14-1 through upregulation of CSR1 in Saccharomyces cerevisiae. FEMS Microbiol. Lett. 216, 165-170.
46. Drawid, A. & Gerstein, J. (2000) A bayesian system integrating expression data with sequence patterns for localizing proteins: comprehensive application to the yeast genome. J. Mol. Biol. 301, 1059-1075.
47. Hirokawa, T., Boon-Chieng, S. & Mitaku, S. (1998) SOSUI: classification and secondary structure prediction system for membrane proteins. Bioinformatics 14, 378-379.
48. De Vries, K.J., Westerman, J., Bastiaens, P.I., Jovin, T.M., Wirtz, K.W. & Snoek, G.T. (1996) Fluorescently labeled phosphatidylinositol transfer protein isoforms (alpha and beta), microinjected into fetal bovine heart endothelial cells, are targeted to distinct intracellular sites. Exp. Cell Res. 227, 33-39.
49. 2+-dependent phosphatidylethanolamine-phospholipase D activity. Eur. J. Biochem. 269, 3821-3830.