Increased missegregation and chromosome loss with decreasing chromosome size in vertebrate cells

Chromosoma

Volumn 115, Issue 1, 2006, Pages 60-74

  Spence, Jennifer M ^a   Mills, Walter ^a   Mann, Kathy ^b,c   Huxley, Clare ^b   Farr, Christine J ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c Cytogenetics Department   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AURORA B KINASE; CENTROMERE PROTEIN A; HISTONE; PROTEIN CENP C; UNCLASSIFIED DRUG;

ANAPHASE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CENTROMERE; CHICKEN; CHROMOSOMAL INSTABILITY; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME LOSS; CHROMOSOME SEGREGATION; CHROMOSOME SIZE; CHROMOSOME STRUCTURE; CORRELATION ANALYSIS; GENETIC ENGINEERING; GENETIC STABILITY; HUMAN; HUMAN CELL; MINICHROMOSOME; MITOSIS; MOUSE; NONHUMAN; PULSED FIELD GEL ELECTROPHORESIS; SOUTHERN BLOTTING; VERTEBRATE; X CHROMOSOME;

ANIMALS; BASE SEQUENCE; BLOTTING, SOUTHERN; CENTROMERE; CHICKENS; CHROMOSOMES; CHROMOSOMES, HUMAN, X; DNA PRIMERS; DNA, RECOMBINANT; ELECTROPHORESIS, GEL, PULSED-FIELD; HUMANS; MITOSIS; NUCLEIC ACID HYBRIDIZATION; VERTEBRATES;

ANIMALIA; MUNTIACUS MUNTJAK; VERTEBRATA;

EID: 31344479087     PISSN: 00095915     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00412-005-0032-6     Document Type: Article

References (56)

1. Alazami A, Mejia JE, Larin Monaco Z (2004) Human artificial chromosomes containing chromosome 17 alphoid DNA maintain an active centromere in murine cells but are not stable. Genomics 83:844-851
2. Andrews PD, Ovechkina Y, Morrice N et al (2004) Aurora B regulates MCAK at the mitotic centromere. Dev Cell 6:253-268
3. Araki K, Araki M, Yamamura K-i (1997) Targeted integration of DNA using mutant lox sites in embryonic stem cells. Nucleic Acids Res 25:868-872
4. Basu J, Willard HF (2005) Artificial and engineered chromosomes: non-integrating vectors for gene therapy. Trends Mol Med 11:251-258
5. Burns EM, Christopoulou L, Corish P, Tyler-Smith C (1999) Quantitative measurement of mammalian chromosome mitotic loss rates using the green fluorescent protein. J Cell Sci 112:2705-2714
6. Conese M, Auriche C, Ascenzioni F (2004) Gene therapy progress and prospects: Episomally maintained self-replicating systems. Gene Ther 11:1735-1741
7. Corish P, Tyler-Smith C (1999) Attenuation of green fluorescent protein half-life in mammalian cells. Protein Eng 12:1035-1040
8. Dieken ES, Fournier REK (1996) Homologous modification of human chromosomal genes in chicken B-cell × human microcell hybrids. Methods 9(1):56-63
9. Dieken ES, Epner EM, Fiering S, Fournier REK, Groudine M (1996) Efficient modification of human chromosomal alleles using recombination-proficient chicken/human microcell hybrids. Nat Genet 12:174-182
10. Dunleavy E, Pidoux A, Allshire RC (2005) Centromeric chromatin makes its mark. Trends Biochem Sci 30:172-175
11. Farr CJ, Stevanovic M, Thomson EJ, Goodfellow PN, Cooke HJ (1992) Telomere-associated chromosome fragmentation: Applications in genome manipulation and analysis. Nat Genet 2:275-282
12. Farr CJ, Bayne RAL, Kipling D, Mills W, Critcher R, Cooke HJ (1995) Generation of a human X-derived minichromosome using telomere-associated chromosome fragmentation. EMBO J 14:5444-5454
13. Featherstone T, Huxley C (1993) Extrachromosomal maintenance and amplification of yeast artificial chromosome DNA in mouse cells. Genomics 17:267-278
14. Feinberg AP, Vogelstein B (1984) A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 137:266-267
15. Fukagawa T (2004) Centromere DNA, proteins and kinetochore assembly in vertebrate cells. Chromosome Res 12:557-567
16. Fukagawa T, Pendon C, Morris J, Brown W (1999) CENP-C is necessary but not sufficient to induce formation of a functional centromere. EMBO J 18:4196-4209
17. Fukagawa T, Mikami Y, Nishihashi A et al (2001) CENP-H, a constitutive centromere component, is required for centromere targeting of CENP-C in vertebrate cells. EMBO J 20:4603-4617
18. Fukagawa T, Nogami M, Yoshikawa M et al (2004) Dicer is essential for formation of the heterochromatin structure in vertebrate cells. Nat Cell Biol 6:784-791
19. Grimes BR, Warburton PE, Farr CJ (2002) Chromosome engineering: prospects for gene therapy. Gene Ther 9:713-718
20. Guenatri M, Bailly D, Maison C, Almouzni G (2004) Mouse centric and pericentric satellite repeats form distinct functional heterochromatin. J Cell Biol 166:493-505
21. Hauf S, Cole RW, LaTerra S et al (2003) The small molecule hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint. J Cell Biol 161:281-294
22. He D, Brinkley BR (1996) Structure and dynamic organization of centromeres/prekinetochores in the nucleus of mammalian cells. J Cell Sci 109:2693-2704
23. Howman AE, Fowler KJ, Newson AJ et al (2000) Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice. Proc Natl Acad Sci U S A 97:1148-1153
24. Ikeno M, Grimes B, Okazaki T et al (1998) Construction of YAC-based mammalian artificial chromosomes. Nat Biotechnol 16:431-439
25. Irvine DV, Amor DJ, Perry J et al (2004) Chromosome size and origin as determinants of the level of CENP-A incorporation into human chromosomes. Chromosome Res 12:805-815
26. Kazuki Y, Shinohara T, Tomizuka K et al (2001) Germline transmission of a transferred human chromosome 21 fragment in transchromosomal mice. J Hum Genet 46:600-603
27. Kuroiwa Y, Tomizuka K, Shinohara T et al (2000) Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts. Nature Biotechnol 18:1086-1090
28. Lee JY, Koi M, Stanbridge EJ, Oshimura M, Kumamoto AT, Feinberg AP (1994) Simple purification of human chromosomes to homogeneity using muntjac hybrid cells. Nat Genet 7:29-33
29. Loupart M-L, Shen MH, Smith A (1998) Differential stability of a human mini-chromosome in mouse cell lines. Chromosoma 107:255-259
30. Mellone BG, Allshire RC (2003) Stretching it: Putting the CEN(P-A) in centromere. Curr Opin Genet Dev 13:191-198
31. Mills W, Critcher R, Lee C, Farr CJ (1999) Generation of an approximately 2.4 Mb human X centromere-based minichromosome by targeted telomere-associated chromosome fragmentation in DT40. Hum Mol Genet 8:751-761
32. Murray AW, Schultes NP, Szostak JW (1986) Chromosome length controls mitotic segregation in yeast. Cell 45:529-536
33. Niwa H, Yamamura K-i, Miyazaki J (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108:193-199
34. Pichugin AM, Galkina SA, Potekhin AA, Punina EO, Rautian MS, Rodionov AV (2001) Determination of the minimum size of Gallus gallus domesticus chicken microchromosome by a pulse electrophoresis method. Genetika 37:657-660
35. Regnier V, Novelli J, Fukagawa T, Vagnarelli P, Brown W (2003) Characterization of chicken CENP-A and comparative sequence analysis of vertebrate centromere-specific histone H3-like proteins. Gene 316:39-46
36. Rudd MK, Mays RW, Schwatz S, Willard HF (2003) Human artificial chromosomes with alpha satellite-based de novo centromeres show increased frequency of non-disjunction and anaphase lag. Mol Cell Biol 23:7689-7697
37. Saitoh H, Tomkiel J, Cooke CA et al (1992) CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate. Cell 70:115-125
38. Sauer B, Henderson N (1990) Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase. New Biol 2:441-449
39. Schafer AJ, Farr CJ (1998) Somatic cell hybrid approaches to mapping. In: Spurr NK, Young BD, Bryant SP (eds) The ICRF handbook of genome analysis. Blackwell, Oxford, pp 321-365
40. Schueler MG, Higgins AW, Rudd MK, Gustashaw K, Willard HF (2001) Genomic and genetic definition of a functional human centromere. Science 294:109-115
41. Shen MH, Mee PJ, Nichols J et al (2000) A structurally defined mini-chromosome vector for the mouse germ line. Curr Biol 10:31-34
42. Shen MH, Yang JW, Pendon C, Brown WR (2001) The accuracy of segregation of human mini-chromosomes varies in different vertebrate cell lines, correlates with the extent of centromere formation and provides evidence for a trans-acting centromere maintenance activity. Chromosoma 109:524-535
43. Shinohara T, Tomizuka K, Takehara S et al (2000) Stability of transferred human chromosome fragments in cultured cells and in mice. Chromosome Res 8:713-725
44. Spence JM, Critcher R, Ebersole TA et al (2002) Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array. EMBO J 21:5269-5280
45. Spence JM, Fournier REK, Oshimura M, Regnier V, Farr CJ (2005) Topoisomerase II cleavage activity within the D11Z1 and DXZ1 alpha-satellite arrays. Chromosome Res 13(6):637-648
46. Sullivan BA, Karpen GH (2004) Centromeric chromatin exhibits a histone modification pattern that is distinct from both euchromatin and heterochromatin. Nat Struct Mol Biol 11:1076-1083
47. Sullivan BA, Warburton PE (1999) Studying the progression of vertebrate chromosomes through mitosis by immunofluorescence and FISH. In: Bickmore WA (ed) Chromosome structural analysis: A practical approach. Oxford University Press, Oxford, pp 82-101
48. Taylor SS, Larin Z, Tyler-Smith C (1996) Analysis of extrachromosomal structures containing human centromeric alphoid satellite DNA sequences in mouse cells. Chromosoma 105:70-81
49. Tomizuka K, Yoshida H, Uejima H et al (1997) Functional expression and germline transmission of a human chromosome fragment in chimaeric mice. Nat Genet 16:133-143
50. Tomizuka K, Shinohara T, Yoshida H et al (2000) Double trans-chromosomic mice: Maintenance of two individual human chromosome fragments containing Ig heavy and kappa loci and expression of fully human antibodies. Proc Natl Acad Sci U S A 97:722-727
51. Valdivia MM, Figueroa J, Iglesias C, Ortiz M (1998) A novel centromere monospecific serum to a human autoepitope on the histone H3-like protein CENP-A. FEBS Lett 422:5-9
52. Voet T, Vermeesch J, Carens A et al (2001) Efficient male and female germline transmission of a human chromosomal vector in mice. Genome Res 11:124-136
53. Voet T, Schoenmakers E, Carpentier S, Labaere C, Marynen P (2003) Controlled transgene dosage and PAC-mediated transgenesis in mice using a chromosomal vector. Genomics 82:596-605
54. Wong LH, Saffery R, Anderson MA, Earle E, Quach JM, Stafford AJ, Fowler KJ, Choo KH (2005) Analysis of mitotic and expression properties of human neocentromere-based transchromosomes in mice. J Biol Chem 280(5):3954-3962
55. Yang J, Pendon C, Yang J, Haywood N, Chand A, Brown WRA (2000) Human mini-chromosomes with minimal centromeres. Hum Mol Genet 9:1891-1902
56. Zou Y, Yi X, Wright WE, Shay JW (2002) Human telomerase can immortalize Indian muntjac cells. Exp Cell Res 281:63-76