Allelic variation in key peptide-binding pockets discriminates between closely related diabetes-protective and diabetes-susceptible HLA-DQB1*06 alleles

Journal of Immunology

Volumn 176, Issue 3, 2006, Pages 1988-1998

  Ettinger, Ruth A ^a,b,e   Papadopoulos, George K ^c   Moustakas, Antonis K ^d   Nepom, Gerald T ^a,b   Kwok, William W ^a,b  

^a BENAROYA RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c Faculty of Agricultural Technology   (Greece)

^d IONIAN UNIVERSITY   (Greece)

^e UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; ARGININE; AROMATIC COMPOUND; AUTOANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; INSULIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OREXIN; PEPTIDE; VALINE;

ACIDITY; ALLELE; ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL BOND; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISEASE PREDISPOSITION; GENETIC POLYMORPHISM; HUMAN; HUMAN CELL; HYDROPHOBICITY; INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN BINDING; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION; SURFACE CHARGE;

EID: 31344435428     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.3.1988     Document Type: Article

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