메뉴 건너뛰기




Volumn 108, Issue SUPPL. 2, 2000, Pages 261-264

Pulmonary toxicity and carcinogenicity of trichloroethylene: Species differences and modes of action

Author keywords

Carcinogenicity; Lung; Mode of action; Species comparisons; TCE; Toxicity; Trichloroethylene

Indexed keywords

CARCINOGEN; CHLORAL; CYTOCHROME P450; TRICHLOROETHYLENE;

EID: 0033947180     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.00108s2261     Document Type: Article
Times cited : (41)

References (58)
  • 1
    • 0026346879 scopus 로고
    • Consideration of the target organ toxicity of trichloroethylene in terms of metabolite toxicity and pharmacokinetics
    • Davidson IWF, Beliles RP. Consideration of the target organ toxicity of trichloroethylene in terms of metabolite toxicity and pharmacokinetics. Drug Metab Rev 23:493-599 (1991).
    • (1991) Drug Metab Rev , vol.23 , pp. 493-599
    • Davidson, I.W.F.1    Beliles, R.P.2
  • 2
    • 0021067936 scopus 로고
    • Inhalation carcinogenicity of trichloroethylene in mice and rats
    • Fukuda K, Takemoto K, Tsurata H. Inhalation carcinogenicity of trichloroethylene in mice and rats. Ind Health 21:243-254 (1983).
    • (1983) Ind Health , vol.21 , pp. 243-254
    • Fukuda, K.1    Takemoto, K.2    Tsurata, H.3
  • 3
    • 0003089789 scopus 로고
    • Experimental research on trichloroethylene carcinogenesis
    • (Maltoni C, Mehlman MA, eds). Princeton, NJ:Princeton Scientific Publishing
    • Maltoni C, Lefermine G, Cotti G. Experimental research on trichloroethylene carcinogenesis In: Archives of Research on Industrial Carcinogenesis, Vol 5 (Maltoni C, Mehlman MA, eds). Princeton, NJ:Princeton Scientific Publishing, 1986;1-393.
    • (1986) Archives of Research on Industrial Carcinogenesis , vol.5 , pp. 1-393
    • Maltoni, C.1    Lefermine, G.2    Cotti, G.3
  • 4
    • 0023690866 scopus 로고
    • Long term carcinogenicity bioassays on trichloroethylene administered by inhalation to Sprague-Dawley rats and Swiss and B6C3F1 mice
    • Maltoni C, Lefemine G, Cotti G, Perino G. Long term carcinogenicity bioassays on trichloroethylene administered by inhalation to Sprague-Dawley rats and Swiss and B6C3F1 mice. Ann NY Acad Sci 534:316-342 (1988).
    • (1988) Ann NY Acad Sci , vol.534 , pp. 316-342
    • Maltoni, C.1    Lefemine, G.2    Cotti, G.3    Perino, G.4
  • 5
    • 0004328487 scopus 로고
    • NCI-CG-TR-2. Bethesda, MD:National Cancer Institute
    • NCI. Carcinogenesis Bioassay of Trichloroethylene. NCI-CG-TR-2. Bethesda, MD:National Cancer Institute, 1976.
    • (1976) Carcinogenesis Bioassay of Trichloroethylene
  • 6
    • 0343745233 scopus 로고
    • NTP TR 232. Bethesda, MD:National Toxicology Program
    • 1 mice. NTP TR 232. Bethesda, MD:National Toxicology Program, 1983.
    • (1983) 1 Mice
  • 7
    • 0343558347 scopus 로고
    • NTP TR 243. Research Triangle Park, NC:National Toxicology Program
    • 1 Mice. NTP TR 243. Research Triangle Park, NC:National Toxicology Program, 1990.
    • (1990) 1 Mice
  • 8
    • 0018840773 scopus 로고
    • Carcinogenicity study of trichloroethylene by long term inhalation in three animal species
    • Henschler D, Romen W, Elsasser HM, Reichert D, Eder E, Radwan Z. Carcinogenicity study of trichloroethylene by long term inhalation in three animal species. Arch Toxicol 43:237-248 (1980).
    • (1980) Arch Toxicol , vol.43 , pp. 237-248
    • Henschler, D.1    Romen, W.2    Elsasser, H.M.3    Reichert, D.4    Eder, E.5    Radwan, Z.6
  • 10
    • 0018731176 scopus 로고
    • Correlation of biochemical and morphological changes induced by chemical injury to the lung
    • Stewart BW, Le Mesurier SM, Lykke AWJ. Correlation of biochemical and morphological changes induced by chemical injury to the lung. Chem-Biol Interact 26:321-338 (1979).
    • (1979) Chem-Biol Interact , vol.26 , pp. 321-338
    • Stewart, B.W.1    Le Mesurier, S.M.2    Lykke, A.W.J.3
  • 11
    • 0342688037 scopus 로고
    • Reduced yield of pulmonary surfactant: Patterns of response following adminstration of chemicals to rats by inhalation
    • Le Mesurier SM, Lykke AWJ, Stewart BW. Reduced yield of pulmonary surfactant: patterns of response following adminstration of chemicals to rats by inhalation. Toxicol Lett 589-93 (1980).
    • (1980) Toxicol Lett , pp. 589-593
    • Le Mesurier, S.M.1    Lykke, A.W.J.2    Stewart, B.W.3
  • 12
    • 0021367335 scopus 로고
    • Some effects of trichloroethylene on mouse lungs and livers
    • Lewis GD, Reynolds RC, Johnson AR. Some effects of trichloroethylene on mouse lungs and livers. Gen Pharmacol 15:139-144 (1984).
    • (1984) Gen Pharmacol , vol.15 , pp. 139-144
    • Lewis, G.D.1    Reynolds, R.C.2    Johnson, A.R.3
  • 14
    • 0023927956 scopus 로고
    • Selective damage of pulmonary nonciliated bronchiolar epithelial (Clara) cells by trichloroethylene in rats
    • Kurasawa K. Selective damage of pulmonary nonciliated bronchiolar epithelial (Clara) cells by trichloroethylene in rats. Jpn J Ind Health 30:121-133 (1988).
    • (1988) Jpn J Ind Health , vol.30 , pp. 121-133
    • Kurasawa, K.1
  • 15
    • 0023676340 scopus 로고
    • Pulmonary toxicity of trichloroethylene: Induction of changes in surfactant phospholipids and phospholipsae A2 acivity in the mouse lung
    • Scott JE, Forkert PG, Oulton M, Rasmussen MG, Temple S, Fraser MO, Whitefield S. Pulmonary toxicity of trichloroethylene: induction of changes in surfactant phospholipids and phospholipsae A2 acivity in the mouse lung. Exp Mol Pathol 49:141-150 (1988).
    • (1988) Exp Mol Pathol , vol.49 , pp. 141-150
    • Scott, J.E.1    Forkert, P.G.2    Oulton, M.3    Rasmussen, M.G.4    Temple, S.5    Fraser, M.O.6    Whitefield, S.7
  • 16
    • 0024533367 scopus 로고
    • Pulmonary toxicity of trichloroethylene in mice
    • Forkert PG, Birch DW. Pulmonary toxicity of trichloroethylene in mice. Drug Metab Dispos 17:106-113 (1989).
    • (1989) Drug Metab Dispos , vol.17 , pp. 106-113
    • Forkert, P.G.1    Birch, D.W.2
  • 18
    • 0026785626 scopus 로고
    • A mechanism for the development of Clara cell lesions in the mouse lung after exposure to trichloroethylene
    • Odurr J, Foster JR, Green T. A mechanism for the development of Clara cell lesions in the mouse lung after exposure to trichloroethylene. Chem-Biol Interact 83:135-153 (1992).
    • (1992) Chem-biol Interact , vol.83 , pp. 135-153
    • Odurr, J.1    Foster, J.R.2    Green, T.3
  • 19
    • 0028049877 scopus 로고
    • Trichloroethylene-induced pneumotoxicity in fetal and neonatal mice
    • Das RM, Scott JE. Trichloroethylene-induced pneumotoxicity in fetal and neonatal mice. Toxicol Lett 73:227-239 (1994).
    • (1994) Toxicol Lett , vol.73 , pp. 227-239
    • Das, R.M.1    Scott, J.E.2
  • 20
    • 85033504675 scopus 로고    scopus 로고
    • Trichloroethylene induced lung tumors: Studies of the mode of action and comparisons between species
    • Greer T, Mainwaring GW, Foster JR. Trichloroethylene induced lung tumors: studies of the mode of action and comparisons between species. Fundam Appl Toxicol 37:125-130 (1997).
    • (1997) Fundam Appl Toxicol , vol.37 , pp. 125-130
    • Greer, T.1    Mainwaring, G.W.2    Foster, J.R.3
  • 21
    • 0028216685 scopus 로고
    • Trichloroethylene induces pulmonary fibrosis in mice
    • Forkert PG, Forkert L. Trichloroethylene induces pulmonary fibrosis in mice. Can J Physiol Pharmacol 72:205-210 (1994)
    • (1994) Can J Physiol Pharmacol , vol.72 , pp. 205-210
    • Forkert, P.G.1    Forkert, L.2
  • 22
    • 0020046982 scopus 로고
    • Trichloroethylene and halothane inhibit uptake of 5-hydroxytryptamine in the isolated perfused rat lung
    • Hede AR, Post C. Trichloroethylene and halothane inhibit uptake of 5-hydroxytryptamine in the isolated perfused rat lung. Biochem Pharmacol 31:353-358 (1982).
    • (1982) Biochem Pharmacol , vol.31 , pp. 353-358
    • Hede, A.R.1    Post, C.2
  • 24
    • 0013605366 scopus 로고
    • The cells of the lung
    • (Nettesheim P, Hanna MG, Deatherage JW, eds). Oak Ridge, TN:U.S. Energy Commission
    • Sorokin SP. The cells of the lung. In: Morphology of Experimental Respiratory Carcinogenesis (Nettesheim P, Hanna MG, Deatherage JW, eds). Oak Ridge, TN:U.S. Energy Commission, 1970;3-43.
    • (1970) Morphology of Experimental Respiratory Carcinogenesis , pp. 3-43
    • Sorokin, S.P.1
  • 25
    • 0018374792 scopus 로고
    • Histologic and ultrastructural features of the Clara cell adenoma of the mouse lung
    • Kauffman SL, Alexander L, Sass L. Histologic and ultrastructural features of the Clara cell adenoma of the mouse lung. Lab Invest 40:708-716 (1979).
    • (1979) Lab Invest , vol.40 , pp. 708-716
    • Kauffman, S.L.1    Alexander, L.2    Sass, L.3
  • 26
    • 0018885566 scopus 로고
    • A scanning electron microscope study of the type II and Clara cell adenoma of the mouse lung
    • Sato T, Kauffman SL. A scanning electron microscope study of the type II and Clara cell adenoma of the mouse lung. Lab Invest 43:28-36 (1980).
    • (1980) Lab Invest , vol.43 , pp. 28-36
    • Sato, T.1    Kauffman, S.L.2
  • 27
    • 0019462455 scopus 로고
    • Histogenesis of the papillary Clara cell adenoma
    • Kauffman SL. Histogenesis of the papillary Clara cell adenoma. Am J Pathol 103:174-180 (1981).
    • (1981) Am J Pathol , vol.103 , pp. 174-180
    • Kauffman, S.L.1
  • 28
    • 0022260601 scopus 로고
    • Clara cell adenomas of the mouse lung
    • Palmer KC. Clara cell adenomas of the mouse lung. Am J Pathol 120 455-463 (1985).
    • (1985) Am J Pathol , vol.120 , pp. 455-463
    • Palmer, K.C.1
  • 29
    • 0022633159 scopus 로고
    • Comparative cytotoxicity of naphthalene and its monomethyl and mononitro derivatives in the mouse lung
    • Rasmussen RE, Do DH, Kim TS, Dearden LC. Comparative cytotoxicity of naphthalene and its monomethyl and mononitro derivatives in the mouse lung. J Appl Toxicol 6:13-20 (1986).
    • (1986) J Appl Toxicol , vol.6 , pp. 13-20
    • Rasmussen, R.E.1    Do, D.H.2    Kim, T.S.3    Dearden, L.C.4
  • 31
    • 0026016258 scopus 로고
    • Cells of origin of primary neoplasms in mice: Morphologic and histochemical studies
    • Thaete LG, Malkinson AM. Cells of origin of primary neoplasms in mice: morphologic and histochemical studies. Exp Lung Res 17:219-228 (1991).
    • (1991) Exp Lung Res , vol.17 , pp. 219-228
    • Thaete, L.G.1    Malkinson, A.M.2
  • 32
    • 0343122336 scopus 로고
    • Pathology of tumours in laboratory animals
    • IARC Scientific Publications no 111 Lyon:International Agency for Research or Cancer
    • IARC. Pathology of tumours in laboratory animals. In: Tumours of the Mouse. Vol 2. IARC Scientific Publications no 111 Lyon:International Agency for Research or Cancer (1994).
    • (1994) Tumours of the Mouse , vol.2
  • 33
    • 0021953443 scopus 로고
    • Immunocytochemical localization of the surfactant apoprotein and Clara cell antigen in chemically induced and naturally occurring pulmonary neoplasms in mice
    • Ward JM, Singh G, Katyal SL, Anderson LM, Kovatch RM. Immunocytochemical localization of the surfactant apoprotein and Clara cell antigen in chemically induced and naturally occurring pulmonary neoplasms in mice. Am J Pathol 118:493-499 (1985).
    • (1985) Am J Pathol , vol.118 , pp. 493-499
    • Ward, J.M.1    Singh, G.2    Katyal, S.L.3    Anderson, L.M.4    Kovatch, R.M.5
  • 34
    • 0017032865 scopus 로고
    • Ultrastructural alterations of nonciliated cells after nitrosamine treatment and their significance for pulmonary carcinogenesis
    • Reznik-Schuller H. Ultrastructural alterations of nonciliated cells after nitrosamine treatment and their significance for pulmonary carcinogenesis. Am J Pathol 85:549-552 (1976).
    • (1976) Am J Pathol , vol.85 , pp. 549-552
    • Reznik-Schuller, H.1
  • 37
    • 0021717844 scopus 로고
    • Nondisjunction induced in mouse spermatogenesis by chloral hydrate, a metabolite of trichloroethylene
    • Russo F, Pacchierotti F, Metalli P. Nondisjunction induced in mouse spermatogenesis by chloral hydrate, a metabolite of trichloroethylene. Environ Mutagen 6:695-703 (1984).
    • (1984) Environ Mutagen , vol.6 , pp. 695-703
    • Russo, F.1    Pacchierotti, F.2    Metalli, P.3
  • 38
    • 0025996671 scopus 로고
    • Evaluation of the mutagenicity of chloral hydrate in vitro and in vivo
    • Leuschner J, Leuschner F Evaluation of the mutagenicity of chloral hydrate in vitro and in vivo. Drug Res 41:1101-1103 (1991).
    • (1991) Drug Res , vol.41 , pp. 1101-1103
    • Leuschner, J.1    Leuschner, F.2
  • 39
    • 0021081798 scopus 로고
    • Interactions of trichloroethylene with DNA in vitro and with RNA and DNA of various mouse tissues in vivo
    • Bergman K. Interactions of trichloroethylene with DNA in vitro and with RNA and DNA of various mouse tissues in vivo. Arch Toxicol 54:181-193 (1983).
    • (1983) Arch Toxicol , vol.54 , pp. 181-193
    • Bergman, K.1
  • 40
    • 0018222406 scopus 로고
    • In vivo studies on the relationship between target organ alkylation and the pulmonary toxicity of a chemically reactive metabolite of 4-ipomeanol
    • Boyd MR, Burka LT. In vivo studies on the relationship between target organ alkylation and the pulmonary toxicity of a chemically reactive metabolite of 4-ipomeanol. J Pharmacol Exp Ther 207:687-697 (1978)
    • (1978) J Pharmacol Exp Ther , vol.207 , pp. 687-697
    • Boyd, M.R.1    Burka, L.T.2
  • 41
    • 0018824250 scopus 로고
    • The pulmonary Clara cell as a target for toxic chemicals requiring metabolic activation; studies with carbon tetrachloride
    • Boyd MR, Statham CN, Longo NS. The pulmonary Clara cell as a target for toxic chemicals requiring metabolic activation; studies with carbon tetrachloride J Pharmacol Exp Ther 22:109-114 (1980).
    • (1980) J Pharmacol Exp Ther , vol.22 , pp. 109-114
    • Boyd, M.R.1    Statham, C.N.2    Longo, N.S.3
  • 42
    • 0020062154 scopus 로고
    • 1,1-Dichloroethylene induced pulmonary injury
    • Forkert PG, Reynolds ES. 1,1-Dichloroethylene induced pulmonary injury. Exp Lung Res 3:57-68 (1982).
    • (1982) Exp Lung Res , vol.3 , pp. 57-68
    • Forkert, P.G.1    Reynolds, E.S.2
  • 43
    • 0022402790 scopus 로고
    • Bromobenzene causes Clara cell camage in mice
    • Forkert PG. Bromobenzene causes Clara cell camage in mice. Can J Physiol Pharmacol 63:1480-1484 (1985).
    • (1985) Can J Physiol Pharmacol , vol.63 , pp. 1480-1484
    • Forkert, P.G.1
  • 44
    • 0024212462 scopus 로고
    • Morphogenesis of O,O,S-trimethyl phosphorothioate induced pulmonary injury in mice
    • Durham SK, Imamura T. Morphogenesis of O,O,S-trimethyl phosphorothioate induced pulmonary injury in mice. Toxicol Appl Pharmacol 96:417-428 (1988).
    • (1988) Toxicol Appl Pharmacol , vol.96 , pp. 417-428
    • Durham, S.K.1    Imamura, T.2
  • 45
    • 0026480664 scopus 로고
    • Pulmonary toxicity of acrylonitrile: Covalent interaction and effect on replicative and unscheduled DNA synthesis in the lung
    • Ahmed AE, Abdel-Aziz AH, Abdel-Rahman SZ, Hague AK, Nouraldeen AM, Shouman SA Pulmonary toxicity of acrylonitrile: covalent interaction and effect on replicative and unscheduled DNA synthesis in the lung. Toxicology 76:1-14 (1992).
    • (1992) Toxicology , vol.76 , pp. 1-14
    • Ahmed, A.E.1    Abdel-Aziz, A.H.2    Abdel-Rahman, S.Z.3    Hague, A.K.4    Nouraldeen, A.M.5    Shouman, S.A.6
  • 46
    • 0026695011 scopus 로고
    • Relationship of cytochrome P-450 activity to Clara cell toxicity. I: Histopathologic comparison of respiratory epithelium in mice, rats and hamsters after parenteral administration of naphthalene
    • Plopper CG, Suverkropp C, Morin O, Buckpitt A, Relationship of cytochrome P-450 activity to Clara cell toxicity. I: Histopathologic comparison of respiratory epithelium in mice, rats and hamsters after parenteral administration of naphthalene. J Pharmacol Exp Ther 261:353-363 (1992).
    • (1992) J Pharmacol Exp Ther , vol.261 , pp. 353-363
    • Plopper, C.G.1    Suverkropp, C.2    Morin, O.3    Buckpitt, A.4
  • 47
    • 77957177161 scopus 로고
    • Methylene chloride: An inhalation study to investigate pathological and biochemical events occurring in the lungs of mice over an exposure period of 90 days
    • Foster JR, Green T, Smith LL, Lewis RW, Hext PM, Wyatt I. Methylene chloride: an inhalation study to investigate pathological and biochemical events occurring in the lungs of mice over an exposure period of 90 days. Fundam Appl Toxicol 18:376-388 (1992).
    • (1992) Fundam Appl Toxicol , vol.18 , pp. 376-388
    • Foster, J.R.1    Green, T.2    Smith, L.L.3    Lewis, R.W.4    Hext, P.M.5    Wyatt, I.6
  • 48
    • 0028101990 scopus 로고
    • Methylene chloride: An inhalation study to investigate toxicity in the mouse lung using morphological, biochemical and Clara cell culture techniques
    • Foster JR, Green T, Smith LL, Tittensor S, Wyatt I. Methylene chloride: an inhalation study to investigate toxicity in the mouse lung using morphological, biochemical and Clara cell culture techniques. Toxicology 91:221-234 (1994).
    • (1994) Toxicology , vol.91 , pp. 221-234
    • Foster, J.R.1    Green, T.2    Smith, L.L.3    Tittensor, S.4    Wyatt, I.5
  • 50
    • 0026035519 scopus 로고
    • Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
    • Guengerich FP, Kim D-H, Iwasaki M. Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem Res Toxicol 4:168-179 (1991).
    • (1991) Chem Res Toxicol , vol.4 , pp. 168-179
    • Guengerich, F.P.1    Kim, D.-H.2    Iwasaki, M.3
  • 51
    • 0026764146 scopus 로고
    • Detection of human lung cytochromes P-450 that are immunochemically related to cytochrome P450IIE1 and cytochrome P-450IIIA
    • Wheeler CW, Wrighton SA, Guenthner TM. Detection of human lung cytochromes P-450 that are immunochemically related to cytochrome P450IIE1 and cytochrome P-450IIIA. Biochem Pharmacol 44:183-186 (1992).
    • (1992) Biochem Pharmacol , vol.44 , pp. 183-186
    • Wheeler, C.W.1    Wrighton, S.A.2    Guenthner, T.M.3
  • 53
    • 0031609238 scopus 로고    scopus 로고
    • Expression of xenobiotic metabolising cytochrome P450's in human pulmonary tissue
    • Raunio H, Hakkola J, Pelkonen O, Edwards R, Boobis A, Anttila S. Expression of xenobiotic metabolising cytochrome P450's in human pulmonary tissue. Arch Toxicol 20:465-469 (1998).
    • (1998) Arch Toxicol , vol.20 , pp. 465-469
    • Raunio, H.1    Hakkola, J.2    Pelkonen, O.3    Edwards, R.4    Boobis, A.5    Anttila, S.6
  • 54
    • 0025654905 scopus 로고
    • Spectroscopic quantitation of cytochrome P-450 in human lung microsomes
    • Wheeler CW, Guenthner TM. Spectroscopic quantitation of cytochrome P-450 in human lung microsomes. J Biochem Toxicol 5:1-4 (1990).
    • (1990) J Biochem Toxicol , vol.5 , pp. 1-4
    • Wheeler, C.W.1    Guenthner, T.M.2
  • 55
    • 0028855791 scopus 로고
    • Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. IV: Metabolism of naphthalene to naphthalene oxide in microdissected airways from mice, rats, and hamsters
    • Buckpitt A, Chang A-M, Weir A, Van Winkle L, Duan X, Philpot R, Plopper C. Relationship of cytochrome P-450 activity to Clara cell cytotoxicity. IV: Metabolism of naphthalene to naphthalene oxide in microdissected airways from mice, rats, and hamsters. Mol Pharmacol 47:74-81 (1995).
    • (1995) Mol Pharmacol , vol.47 , pp. 74-81
    • Buckpitt, A.1    Chang, A.-M.2    Weir, A.3    Van Winkle, L.4    Duan, X.5    Philpot, R.6    Plopper, C.7
  • 56
    • 0018360024 scopus 로고
    • The Clara cell: A complete ultrastructural study in mammals
    • Smith MN, Greenberg DS, Spjut HJ. The Clara cell: a complete ultrastructural study in mammals. Am J Anat 155:15-30 (1979).
    • (1979) Am J Anat , vol.155 , pp. 15-30
    • Smith, M.N.1    Greenberg, D.S.2    Spjut, H.J.3
  • 57
    • 0019301282 scopus 로고
    • Infrastructure of the nonciliated bronchiolar epithelial (Clara) cell of mammalian lung. I: A comparison of rabbit, guinea pig, rat, hamster and mouse
    • Plopper CG, Mariassy AT, Hill LH. Infrastructure of the nonciliated bronchiolar epithelial (Clara) cell of mammalian lung. I: A comparison of rabbit, guinea pig, rat, hamster and mouse. Exp Lung Res 1:139-154 (1980).
    • (1980) Exp Lung Res , vol.1 , pp. 139-154
    • Plopper, C.G.1    Mariassy, A.T.2    Hill, L.H.3
  • 58
    • 0019293941 scopus 로고
    • Ultrastructure of the nonciliated bronchiolar epithelial (Clara) cell of mammalian lung. III: A study of man with comparison of 15 mammalian species
    • Plopper CG, Hill LH, Mariassy AT. Ultrastructure of the nonciliated bronchiolar epithelial (Clara) cell of mammalian lung. III: A study of man with comparison of 15 mammalian species. Exp Lung Res 1:171-180 (1980).
    • (1980) Exp Lung Res , vol.1 , pp. 171-180
    • Plopper, C.G.1    Hill, L.H.2    Mariassy, A.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.