Bioactivation of 1,1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung

Journal of Pharmacology and Experimental Therapeutics

Volumn 310, Issue 3, 2004, Pages 855-864

  Simmonds, Andrea C ^a   Ghanayem, Burhan I ^b   Sharma, Ashish ^a   Reilly, Christopher A ^c   Millen, Brandie ^a   Yost, Garold S ^c   Forkert, Poh Gek ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF UTAH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 NITROPHENOL; 5 PHENYL 1 PENTYNE; CHLORZOXAZONE; CYTOCHROME P450 2E1; CYTOCHROME P450 2F2; CYTOCHROME P450 ISOENZYME; DIALLYL DISULFIDE; DIALLYL SULFONE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG; VINYLIDENE CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHIOLE; CLARA CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME MECHANISM; FEMALE; HYDROXYLATION; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LUNG INJURY; LUNG TOXICITY; MICROSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; WESTERN BLOTTING; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; CHLORZOXAZONE; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; CYTOSOL; DICHLOROETHYLENES; FEMALE; HYDROXYLATION; LUNG; MICE; NITROPHENOLS;

EID: 4143123097     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.068171     Document Type: Article

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