Cytochrome P450-dependent metabolism of trichloroethylene in rat kidney

Toxicological Sciences

Volumn 60, Issue 1, 2001, Pages 11-19

  Cummings, Brian S ^a   Parker, Jean C ^b   Lash, Lawrence H ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Cytochrome P450; Enzyme induction; Kidney; Metabolism; Proximal tubular cells; Trichloroethylene

Indexed keywords

CHLORAL HYDRATE; CHLORZOXAZONE; CLOFIBRATE; CYTOCHROME P450; CYTOCHROME P450 2C11; CYTOCHROME P450 2E1; PROADIFEN; PYRIDINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TRICHLOROETHYLENE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ISOLATION; CONTROLLED STUDY; ENZYME SUBSTRATE; KIDNEY DISTAL TUBULE; KIDNEY HOMOGENATE; KIDNEY METABOLISM; KIDNEY MICROSOME; KIDNEY PROXIMAL TUBULE; LIVER HOMOGENATE; LIVER METABOLISM; LIVER MICROSOME; MALE; MEASUREMENT; METABOLITE; NONHUMAN; PROTEIN EXPRESSION; RAT; TIME;

ANIMALS; BLOTTING, WESTERN; CHLORAL HYDRATE; CHLORZOXAZONE; CLOFIBRATE; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME INDUCTION; KIDNEY TUBULES, DISTAL; KIDNEY TUBULES, PROXIMAL; MALE; MICROSOMES, LIVER; PROADIFEN; PYRIDINES; RATS; RATS, INBRED F344; TRICHLOROETHYLENE;

ANIMALIA;

EID: 0035092716     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/60.1.11     Document Type: Article

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