Differential responses of human brain cells to West Nile virus infection

Journal of NeuroVirology

Volumn 11, Issue 6, 2005, Pages 512-524

  Cheeran, Maxim C J ^a   Hu, Shuxian ^a   Sheng, Wen S ^a   Rashid, Ayesha ^a   Peterson, Phillip K ^a   Lokensgard, James R ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

Chemokines; Cytokines; Glia; West Nile virus

Indexed keywords

ALPHA INTERFERON; CHEMOKINE; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ASTROCYTE; BRAIN INFECTION; BRAIN NERVE CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MICROGLIA; NERVE CELL CULTURE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VIROGENESIS; VIRUS REPLICATION; WEST NILE FLAVIVIRUS;

ANIMALS; ASTROCYTES; BRAIN; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CHEMOKINES, CXC; CHEMOTAXIS; CYTOKINES; HUMANS; NEURONS; VERO CELLS; WEST NILE VIRUS;

FLAVIVIRUS; WEST NILE VIRUS;

EID: 31144454437     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.1080/13550280500384982     Document Type: Article

References (62)

1. Ajmone-Cat, M and Nicolini, A and Minghetti, L. (2003) Prolonged exposure of microglia to lipopolysaccharide modifies the intracellular signaling pathways and selectively promotes prostaglandin E2 synthesis J Neurochem, 87, pp. 1193 - 1203. [PUBMED] [INFOTRIEVE] [CSA]
2. Becher, B and Prat, A and Antel, J. (2000) Brain-immune connection: immuno-regulatory properties of CNS-resident cells Glia, 29, pp. 293 - 304. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
3. Ben-Nathan, D and Huitinga, I and Lustig, S and van Rooijen, N and Kobiler, D. (1996) West Nile virus neuroinvasion and encephalitis induced by macrophage depletion in mice Arch Virol, 141, pp. 459 - 469. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
4. Benveniste, E.(1997) Cytokine expression in the nervous system. In Immunology of the nervous system. (pp. 419 - 459). New York: Oxford University Press.
5. Binder, G and Griffin, D. (2003) Immune-mediated clearance of virus from the central nervous system Microbes Infect, 5, pp. 439 - 448. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
6. Cardosa, M and Gordon, S and Hirsch, S and Springer, T and Porterfield, J. (1986) Interaction of West Nile virus with primary murine macrophages: Role of cell activation and receptors for antibody and complement J Virol, 57, pp. 952 - 959. [PUBMED] [INFOTRIEVE] [CSA]
7. Carson, M and Sutcliffe, J. (1999) Balancing function vs. self defense: the CNS as an active regulator of immune responses J Neurosci Res, 55, pp. 1 - 8. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
8. Cartier, L and Hartley, O and Dubois-Dauphin, M and Krause, K. (2005) Chemokine receptors in the central nervous system: Role in brain inflammation and neurodegenerative diseases Brain Res Brain Res Rev, 48, pp. 16 - 42. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
9. Ceccaldi, P and Lucas, M and Despres, P. (2004) New insights on the neuropathology of West Nile virus FEMS Microbiol Lett, 233, pp. 1 - 6. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
10. Chambers, T and Diamond, M. (2003) Pathogenesis of flavivirus encephalitis Adv Virus Res, 60, pp. 273 - 342. [PUBMED] [INFOTRIEVE] [CSA]
11. Chao, C and Gekker, G and Hu, S and Peterson, P. (1994) Human microglial cell defense against Toxoplasma gondii. The role of cytokines J Immunol, 152, pp. 1246 - 1252. [PUBMED] [INFOTRIEVE] [CSA]
12. Chao, C and Hu, S. (1994) Tumor necrosis factor-alpha potentiates glutamate neurotoxicity in human fetal brain cell cultures Dev Neurosci, 16, pp. 172 - 179. [PUBMED] [INFOTRIEVE] [CSA]
13. Cheeran, M and Gekker, G and Hu, S and Palmquist, J and Lokensgard, J. (2005) T cell-mediated restriction of intracerebral murine cytomegalovirus infection displays dependence upon perofrin but not interferon-gamma J NeuroVirol, 11, pp. 274 - 280. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
14. Cheeran, M and Gekker, G and Hu, S and Min, X and Cox, D and Lokensgard, J. (2004) Intracerebral infection with murine cytomegalovirus induces CXCL10 and is restricted by adoptive transfer of splenocytes J NeuroVirol, 10, pp. 152 - 162. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
15. Cheeran, M and Hu, S and Sheng, W and Peterson, P and Lokensgard, J. (2003) CXCL10 production from cytomegalovirus-stimulated microglia is regulated by both human and viral interleukin-10 J Virol, 77, pp. 4502 - 4515. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
16. Cheeran, M and Hu, S and Yager, S and Gekker, G and Peterson, P and Lokensgard, J. (2001) Cytomegalovirus induces cytokine and chemokine production differentially in microglia and astrocytes: Antiviral implications J NeuroVirol, 7, pp. 135 - 147. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
17. Cheng, Y and King, N and Kesson, A. (2004) The role of tumor necrosis factor in modulating responses of murine embryo fibroblasts by flavivirus, West Nile Virology, 329, pp. 361 - 370. [PUBMED] [INFOTRIEVE] [CSA]
18. Christensen, J and Nansen, A and Moos, T and Lu, B and Gerard, C and Christensen, J and Thomsen, A. (2004) Efficient T-cell surveillance of the CNS requires expression of the CXC chemokine receptor 3 J Neurosci, 24, pp. 4849 - 4858. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
19. Chu, J and Ng, M. (2004) Interaction of West Nile virus with alpha v beta 3 integrin mediates virus entry into cells J Biol Chem, 279, pp. 54533 - 54541. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
20. Diamond, M and Shrestha, B and Marri, A and Mahan, D and Engle, M. (2003a) B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus J Virol, 77, pp. 2578 - 2586. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
21. Diamond, M and Sitati, E and Friend, L and Higgs, S and Shrestha, B and Engle, M. (2003b) A critical role for induced IgM in the protection against West Nile virus infection J Exp Med, 198, pp. 1853 - 1862. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
22. Dong, Y and Benveniste, E. (2001) Immune function of astrocytes Glia, 36, pp. 180 - 190. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
23. Edelmann, K and Richardson-Burns, S and Alexopoulou, L and Tyler, K and Flavell, R and Oldstone, M. (2004) Does Toll-like receptor 3 play a biological role in virus infections? Virology, 322, pp. 231 - 238. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
24. Farina, C and Krumbholz, M and Giese, T and Hartmann, G and Aloisi, F and Meinl, E. (2005) Preferential expression and function of Toll-like receptor 3 in human astrocytes J Neuroimmunol, 159, pp. 12 - 19. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
25. Garmendia, A and Van Kruiningen, H and French, R. (2001) The West Nile virus: Its recent emergence in North America Microbes Infect, 3, pp. 223 - 229. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
26. Granwehr, B and Lillibridge, K and Higgs, S and Mason, P and Aronson, J and Campbell, G and Barrett, A. (2004) West Nile virus: Where are we now? Lancet Infect Dis, 4, pp. 547 - 556. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
27. Guarner, J and Shieh, W and Hunter, S and Paddock, C and Morken, T and Campbell, G and Marfin, A and Zaki, S. (2004) Clinicopathologic study and laboratory diagnosis of 23 cases with West Nile virus encephalomyelitis Hum Pathol, 35, pp. 983 - 990. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
28. Guillot, L and Le Goffic, R and Bloch, S and Escriou, N and Akira, S and Chignard, M and Si-Tahar, M. (2005) Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus J Biol Chem, 280, pp. 5571 - 5580. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
29. Halevy, M and Akov, Y and Ben-Nathan, D and Kobiler, D and Lachmi, B and Lustig, S. (1994) Loss of active neuroinvasiveness in attenuated strains of West Nile virus: Pathogenicity in immunocompetent and SCID mice Arch Virol, 137, pp. 355 - 370. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
30. Hesselgesser, J and Horuk, R. (1999) Chemokine and chemokine receptor expression in the central nervous system J NeuroVirol, 5, pp. 13 - 26. [PUBMED] [INFOTRIEVE] [CSA]
31. Johnson, R. (2003) Emerging viral infections of the nervous system J NeuroVirol, 9, pp. 140 - 147. [PUBMED] [INFOTRIEVE] [CSA]
32. Johnston, L and Halliday, G and King, N. (2000) Langerhans cells migrate to local lymph nodes following cutaneous infection with an arbovirus J Invest Dermatol, 114, pp. 560 - 568. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
33. Jordan, I and Briese, T and Fischer, N and Lau, J and Lipkin, W. (2000) Ribavirin inhibits West Nile virus replication and cytopathic effect in neural cells J Infect Dis, 182, pp. 1214 - 1217. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
34. Kim, B and Palma, J and Kwon, D and Fuller, A. (2005) Innate Immune Response Induced by Theiler's Murine Encephalomyelitis Virus Infection Immunol Res, 31, pp. 1 - 12. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
35. Klee, A and Maidin, B and Edwin, B and Poshni, I and Mostashari, F and Fine, A and Layton, M and Nash, D. (2004) Long-term prognosis for clinical West Nile virus infection Emerg Infect Dis, 10, pp. 1405 - 1411. [PUBMED] [INFOTRIEVE] [CSA]
36. Kleinschmidt-DeMasters, B and Marder, B and Levi, M and Laird, S and McNutt, J and Escott, E and Everson, G and Tyler, K. (2004) Naturally acquired West Nile virus encephalomyelitis in transplant recipients: clinical, laboratory, diagnostic, and neuropathological features Arch Neurol, 61, pp. 1210 - 1220. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
37. Kulkarni, A and Mullbacher, A and Blanden, R. (1991) Functional analysis of macrophages, B cells and splenic dendritic cells as antigen-presenting cells in West Nile virus-specific murine T lymphocyte proliferation Immunol Cell Biol, 69, pp. 71 - 80. [PUBMED] [INFOTRIEVE] [CSA]
38. Lanciotti, R and Roehrig, J and Deubel, V and Smith, J and Parker, M and Steele, K and Crise, B and Volpe, K and Crabtree, M and Scherret, J and Hall, R and Mac Kenzie, J and Cropp, C and Panigrahy, B and Ostlund, E and Schmitt, B and Malkinson, M and Banet, C and Weissman, J and Komar, N and Savage, H and Stone, W and McNamara, T and Gubler, D. (1999) Origin of the West Nile virus responsible for an outbreak of encephalitis in the northeastern United States Science, 286, pp. 2333 - 2337. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
39. Liu, Y and Blanden, R and Mullbacher, A. (1989) Identification of cytolytic lymphocytes in West Nile virus-infected murine central nervous system J Gen Virol, 70, pp. 565 - 573. [PUBMED] [INFOTRIEVE] [CSA]
40. Liu, Y and King, N and Kesson, A and Blanden, R and Mullbacher, A. (1988) West Nile virus infection modulates the expression of class I and class II MHC antigens on astrocytes in vitro Ann N Y Acad Sci, 540, pp. 483 - 485. [PUBMED] [INFOTRIEVE] [CSA]
41. Lokensgard, J and Cheeran, M and Hu, S and Gekker, G and Peterson, P. (2002) Glial cell responses to herpesvirus infections: Role in defense and immunopathogenesis J Infect Dis, 186, pp. S171 - S179. Suppl 2 [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
42. Malmgaard, L and Melchjorsen, J and Bowie, A and Mogensen, S and Paludan, S. (2004) Viral activation of macrophages through TLR-dependent and -independent pathways J Immunol:, 173, pp. 6890 - 6898. [CSA]
43. Marques, C and Hu, S and Sheng, W and Cheeran, M and Cox, D and Lokensgard, J. (2004) Interleukin-10 attenuates production of HSV-induced inflammatory mediators by human microglia Glia, 47, pp. 358 - 366. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
44. Oh, J and Schwiebert, L and Benveniste, E. (1999) Cytokine regulation of CC and CXC chemokine expression by human astrocytes J NeuroVirol, 5, pp. 82 - 94. [PUBMED] [INFOTRIEVE] [CSA]
45. Olson, J and Miller, S. (2004) Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs J Immunol, 173, pp. 3916 - 3924. [PUBMED] [INFOTRIEVE] [CSA]
46. Pantelic, L and Sivakumaran, H and Urosevic, N. (2005) Differential induction of antiviral effects against West Nile virus in primary mouse macrophages derived from flavivirus-susceptible and congenic resistant mice by alpha/beta interferon and poly(I-C) J Virol, 79, pp. 1753 - 1764. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
47. Parsons, J. (2003) Focal adhesion kinase: The first ten years J Cell Sci, 116, pp. 1409 - 1416. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
48. Peterson, P and Hu, S and Salak-Johnson, J and Molitor, T and Chao, C. (1997) Differential production of and migratory response to beta chemokines by human microglia and astrocytes J Infect Dis, 175, pp. 478 - 481. [PUBMED] [INFOTRIEVE] [CSA]
49. Pierson, T and Diamond, M and Ahmed, A and Valentine, L and Davis, C and Samuel, M and Hanna, S and Puffer, B and Doms, R. (2005) An infectious West Nile Virus that expresses a GFP reporter gene Virology, 334, pp. 28 - 40. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
50. Poluektova, L and Gorantla, S and Faraci, J and Birusingh, K and Dou, H and Gendelman, H. (2004) Neuroregulatory events follow adaptive immune-mediated elimination of HIV-1-infected macrophages: Studies in a murine model of viral encephalitis J Immunol, 172, pp. 7610 - 7617. [PUBMED] [INFOTRIEVE] [CSA]
51. Rempel, J and Murray, S and Meisner, J and Buchmeier, M. (2004) Differential regulation of innate and adaptive immune responses in viral encephalitis Virology, 318, pp. 381 - 392. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
52. Rock, R and Gekker, G and Hu, S and Sheng, W and Cheeran, M and Lokensgard, J and Peterson, P. (2004) Role of microglia in central nervous system infections Clin Microbiol Rev, 17, pp. 942 - 964. Table of Contents [PUBMED] [INFOTRIEVE] [CSA]
53. Schneider-Schaulies, J and Liebert, U and Dorries, R and Meullen, V.(1997) Establishment and control of viral infections of the nervous system. In Immunology of the nervous system. (pp. 576 - 610). New York: Oxfo rd University Press.
54. Sejvar, J and Haddad, M and Tierney, B and Campbell, G and Marfin, A and Van Gerpen, J and Fleischauer, A and Leis, A and Stokic, D and Petersen, L. (2003) Neurologic manifestations and outcome of West Nile virus infection JAMA, 290, pp. 511 - 515. [PUBMED] [INFOTRIEVE] [CSA]
55. Shirato, K and Kimura, T and Mizutani, T and Kariwa, H and Takashima, I. (2004) Different chemokine expression in lethal and non-lethal murine West Nile virus infection J Med Virol, 74, pp. 507 - 513. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
56. Shrestha, B and Diamond, M. (2004) Role of CD8+ T cells in control of West Nile virus infection J Virol, 78, pp. 8312 - 8321. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
57. Shrestha, B and Gottlieb, D and Diamond, M. (2003) Infection and injury of neurons by West Nile encephalitis virus J Virol, 77, pp. 13203 - 13213. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
58. Wang, T and Scully, E and Yin, Z and Kim, J and Wang, S and Yan, J and Mamula, M and Anderson, J and Craft, J and Fikrig, E. (2003a) IFN-gamma-producing gamma delta T cells help control murine West Nile virus infection J Immunol, 171, pp. 2524 - 2531. [PUBMED] [INFOTRIEVE] [CSA]
59. Wang, T and Town, T and Alexopoulou, L and Anderson, J and Fikrig, E and Flavell, R. (2004) Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis Nat Med, 10, pp. 1366 - 1373. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
60. Wang, Y and Lobigs, M and Lee, E and Mullbacher, A. (2003b) CD8+ T cells mediate recovery and immunopathology in West Nile virus encephalitis J Virol, 77, pp. 13323 - 13334. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
61. Winter, P and Dung, N and Loan, H and Kneen, R and Wills, B and Thu le, T and House, D and White, N and Farrar, J and Hart, C and Solomon, T. (2004) Proinflammatory cytokines and chemokines in humans with Japanese encephalitis J Infect Dis, 190, pp. 1618 - 1626. [PUBMED] [INFOTRIEVE] [CROSSREF] [CSA]
62. Xiao, S and Guzman, H and Zhang, H and Travassos da Rosa, A and Tesh, R. (2001) West Nile virus infection in the golden hamster (Mesocricetus auratus): A model for West Nile encephalitis Emerg Infect Dis, 7, pp. 714 - 721. [PUBMED] [INFOTRIEVE] [CSA]