Co2(CO)8-catalyzed intramolecular hetero-Pauson-Khand reaction of alkynecarbodiimide: Synthesis of (±)-physostigmine

Organic Letters

Volumn 8, Issue 1, 2006, Pages 83-86

  Mukai, Chisato ^a   Yoshida, Tatsunori ^a   Sorimachi, Mao ^a   Odani, Akira ^b  

^a KANAZAWA UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYNE; CYANAMIDE; PHYSOSTIGMINE;

ARTICLE; CATALYSIS; CHEMISTRY; SYNTHESIS;

ALKYNES; CARBODIIMIDES; CATALYSIS; PHYSOSTIGMINE;

EID: 30944460158     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol052562z     Document Type: Article

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55. 8 (20 mol %) was used.
56. 6 (1.2 equiv) and DMSO (10 equiv) afforded the desired 9 in 78% yield along with the urea 7 in 8% yield.
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