A rapid synthesis of hydroxymethylacylfulvene (HMAF) using the allenic Pauson-Khand reaction. A synthetic approach to either enantiomer of this illudane structure

Journal of the American Chemical Society

Volumn 122, Issue 20, 2000, Pages 4915-4920

  Brummond, Kay M ^a   Lu, Jianliang ^a   Petersen, Jeffrey ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 HYDROXYMETHYLACYLFULVENE; ANTINEOPLASTIC AGENT; ILLUDIN M; ILLUDIN S; UNCLASSIFIED DRUG;

ALKYLATION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL REACTION; CLINICAL TRIAL; DRUG STRUCTURE; ENANTIOMER; HUMAN; PHASE 2 CLINICAL TRIAL; RACEMIC MIXTURE; SOLID TUMOR; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

EID: 0034709394     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja000546l     Document Type: Article

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