Enantiocontrolled synthesis of the epoxycyclohexenone moieties of scyphostatin, a potent and specific inhibitor of neutral sphingomyelinase

Tetrahedron

Volumn 62, Issue 7, 2006, Pages 1590-1608

  Katoh, Tadashi ^a   Izuhara, Takashi ^b   Yokota, Wakako ^c   Inoue, Munenori ^c   Watanabe, Kazuhiro ^a   Nobeyama, Ayaka ^a   Suzuki, Takeyuki ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^c SAGAMI CHEMICAL RESEARCH CENTER   (Japan)

Author keywords

Aldol type coupling; Diels Alder reaction; Sphingomyelinase

Indexed keywords

BENZALDEHYDE; SCYPHOSTATIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELIN PHOSPHODIESTERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG INHIBITION; DRUG MECHANISM; DRUG PURITY; DRUG SYNTHESIS; ENANTIOSELECTIVITY; ENZYME INHIBITION; PRIORITY JOURNAL; STEREOSPECIFICITY;

BETULACEAE;

EID: 30844472661     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2005.10.082     Document Type: Article

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